cimb-logo

Journal Browser

Journal Browser

The Contribution and Application of Molecular Biology in the Applied Biosciences—Focusing on Medicine, Biomaterials and Tissue Engineering Fields, 3rd Edition

A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Biochemistry, Molecular and Cellular Biology".

Deadline for manuscript submissions: 31 October 2026 | Viewed by 353

Special Issue Editors


E-Mail
Guest Editor
1. Lab of Computing, Medical Informatics and Biomedical Imaging Technologies, School of Medicine, AUTH, 54124 Thessaloniki, Greece
2. Department of Prosthodontics, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
Interests: oxidative stress; reactive oxygen species; antioxidants; genetic profile; immunity; disease pathogenesis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The rapid development of new approaches and techniques in molecular biology has led to new insights in medicine regarding clinical applications and biomaterial science for tissue engineering approaches. More specifically, investigative methods within molecular biology have made progress in uncovering fundamental medical processes that are revealed when we fully understand their molecular details. Cloning tools, CRISPR/Cas9 technology, DNA arrays, and next-generation sequencing (NGS) are some of the tools used in guiding drug discovery and developing diagnostic methods. The information that arises thanks to their use, in addition to patients’ reported outcomes, covers all the elements that we must take into consideration in routine clinical decision-making strategies to optimize treatment benefits for patients. Additionally, as molecular biologists progressively discover the pathogenetic mechanisms that underly several entities, evidence regarding the correct combination of extracellular and intracellular chemical gradients, cellular attachment complexes and other stimuli required to activate tissue regeneration is revealed. The aim of this Special Issue is to gather relevant new insights and updates from the fields of medicine, biomaterials, and tissue engineering under the prism of molecular biology tools to obtain a more comprehensive view of the obstacles and challenges that are raised.

You can read the first volume and second volume of our Special Issue by clicking the following link:

https://www.mdpi.com/journal/cimb/special_issues/0SJG097B17

https://www.mdpi.com/journal/cimb/special_issues/78R334426C

Dr. Ioannis Tsamesidis
Dr. Evangelia Stalika
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • medicine
  • biomaterials
  • tissue engineering
  • molecular biology
  • patients’ reported outcomes
  • personalized medicine

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

27 pages, 2406 KB  
Review
The Potential and Prospects of Hydrogel Applications in Traumatic Brain Injury Treatment
by Cheng Zhong, Jie Li, Dengzhuo Liu, Xinran He, Zihao Fan, Xinxin Guo and Guangwei Wang
Curr. Issues Mol. Biol. 2026, 48(5), 488; https://doi.org/10.3390/cimb48050488 - 8 May 2026
Viewed by 194
Abstract
Traumatic brain injury (TBI) is a prevalent neurological disorder that induces severe neurological dysfunction and markedly reduces quality of life owing to its complex pathophysiology and limited therapeutic options. Conventional pharmacological and surgical interventions show restricted efficacy because of poor blood–brain barrier penetration [...] Read more.
Traumatic brain injury (TBI) is a prevalent neurological disorder that induces severe neurological dysfunction and markedly reduces quality of life owing to its complex pathophysiology and limited therapeutic options. Conventional pharmacological and surgical interventions show restricted efficacy because of poor blood–brain barrier penetration and inability to address secondary injury cascades. In recent years, hydrogels have shown significant potential for TBI repair due to their superior biocompatibility, high water content, and ability to mimic the native extracellular matrix (ECM). This review systematically examines recent advances in hydrogel applications for TBI therapy, focusing on their roles as drug delivery platforms, stem cell scaffolds, neuroregeneration promoters, inflammation modulators, and angiogenesis facilitators. Particular emphasis is placed on the therapeutic benefits and underlying mechanisms of ECM-derived hydrogels, self-assembling peptide (SAP) hydrogels, stimuli-responsive smart hydrogels, and functionalized multicomponent systems. Current challenges and limitations in hydrogel applications are also discussed, along with future research directions, to provide scientific rationale and practical guidance for precision TBI therapy. Full article
Show Figures

Figure 1

Back to TopTop