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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Biology, Diagnosis and Management of Endometrial Cancer

edited by

Georgios Androutsopoulos

Georgios Michail

and Thomas Vrekoussis

submission deadline 12 Jul 2026 | 5 articles | Viewed by 12939 | Submission Open

Keywords: endometrial cancer; molecular biology; lymph node dissection; sentinel lymph node mapping; sentinel lymph node dissection; surgery; systemic therapy; radiotherapy; fertility preservation; molecular targeted therapies

(This special issue belongs to the Section Molecular Cancer Biology)

The Role of Flow Cytometry in Hematologic Malignancies

edited by

Kristy Wolniak

and Lucy Fu

submission deadline 12 Jul 2026 | 1 articles | Viewed by 1426 | Submission Open

Keywords: flow cytometry; hematology; oncology; malignancy; lymphoma; leukemia; pathology; innovation; methodology; diagnosis

(This special issue belongs to the Section Methods and Technologies Development)

Advances in Hodgkin Lymphoma (HL)

edited by

Antonino Carbone

submission deadline 15 Jul 2026 | 3 articles | Viewed by 9256 | Submission Open

Keywords: classic Hodgkin lymphoma; diagnostic challenges; tumour microenvironment; variability in disease extent; TME-targeted therapies; personalized treatment; relapsed/refractory cHL

(This special issue belongs to the Section Cancer Pathophysiology)

Recent Advances in Liquid Biopsy Biomarkers of Cancer

edited by

Hua-Jun He

submission deadline 15 Jul 2026 | 3 articles | Viewed by 6231 | Submission Open

Keywords: liquid biopsy; circulating tumor cells; circulating tumor DNA; extracellular vesicles; circulating RNA; cfDNA methylation; fragmentome; reference material; miRNA; multi-cancer detection

(This special issue belongs to the Section Cancer Biomarkers)

Tumor Microenvironment of Gynecological Tumors

edited by

Zahid Pranjol

and

Dmitry Aleksandrovich Zinovkin

submission deadline 15 Jul 2026 | 4 articles | Viewed by 4565 | Submission Open

Keywords: tumor microenvironment; gynecological cancers; immunomodulation; cancer-associated fibroblasts; angiogenesis; cancer-like stem cells; extracellular matrix; immune evasion; cell signaling; therapeutics

(This special issue belongs to the Section Tumor Microenvironment)

Penile Cancer and Rare Urogenital Malignancies: From Biology to Clinical Management

edited by

Mateusz Czajkowski

and Marcin Matuszewski

submission deadline 15 Jul 2026 | 3 articles | Viewed by 3879 | Submission Open

Keywords: penile cancer; urethral carcinoma; upper tract urothelial carcinoma; rare urogenital tumors; surgical management; systemic therapy; epidemiology

Tumor Microenvironment of Breast Cancer—2nd Edition

edited by

Masanori Oshi

submission deadline 15 Jul 2026 | 3 articles | Viewed by 3514 | Submission Open

Keywords: breast cancer; tumor microenvironment; TME; stromal cells

(This special issue belongs to the Section Tumor Microenvironment)

Molecular Signatures of Therapy: Biomarkers Predicting Response and Relapse in Cancer

edited by

Antonis Giakountis

submission deadline 15 Jul 2026 | 3 articles | Viewed by 3291 | Submission Open

Keywords: molecular biomarkers; therapeutic response; disease relapse; precision oncology; liquid biopsy; predictive biomarkers; multi-omics integration; minimal residual disease; translational oncology

(This special issue belongs to the Section Cancer Biomarkers)

Integrating Chemotherapy and Immunotherapy for Head and Neck Cancer

edited by Ken Saijo

submission deadline 15 Jul 2026 | 1 articles | Viewed by 2735 | Submission Open

Keywords: head and neck squamous cell carcinomas; HNSCC; immune checkpoint inhibitor; biomarker; chemotherapy

(This special issue belongs to the Section Cancer Metastasis)

Advances in Clinical Surgery for Gynecological Cancers

edited by

Sebastian Szubert

submission deadline 15 Jul 2026 | 1 articles | Viewed by 2617 | Submission Open

Keywords: ovarian cancer; endometrial cancer; cervical cancer; gynecological surgery; gynecological oncology; reconstructive surgery; pelvic exenteration; supportive cancer care

(This special issue belongs to the Section Methods and Technologies Development)

The Survival of Colon and Rectal Cancer (2nd Edition)

edited by

Susanne Merkel

submission deadline 15 Jul 2026 | 2 articles | Viewed by 2374 | Submission Open

Keywords: colorectal cancer; colorectal cancer surgery; multidisciplinary treatment; survival; prognostic factors; distant metastasis; locoregional recurrences; standardisation; individualisation

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Radiologic Imaging of Hepatocellular Carcinomas

edited by

Masakatsu Tsurusaki

submission deadline 15 Jul 2026 | 1 articles | Viewed by 809 | Submission Open

Keywords: machine learning/deep learning; radiomics; imaging biomarkers; hepatocellular carcinoma; CT; MRI; PET/CT; Gd-EOB-DTPA; LI-RADS; therapeutic response assessment

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Robotic Versus Laparoscopic Surgery for Colorectal Cancer

edited by Richard Garfinkle and Nicholas P. McKenna

submission deadline 15 Jul 2026 | Viewed by 327 | Submission Open

Keywords: colon cancer; rectal cancer; colorectal cancer; robotic surgery; laparoscopic surgery; transanal surgery; minimally invasive surgery

(This special issue belongs to the Section Methods and Technologies Development)

Myelodysplastic Neoplasms (MDS) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN): New Insights into Diagnosis and Targeted Therapy

edited by

Ling Zhang

, David Sallman and Deniz Peker

submission deadline 15 Jul 2026 | Viewed by 282 | Submission Open

Keywords: myelodysplastic syndromes/myelodysplastic neoplasms (MDS); myelodysplastic/myeloproliferative neoplasm; chronic myelomonocytic leukemia (CMML); diagnosis; mutations; IPSS-R; IPSS-M; hypomethylation agents; targeted therapy; hematopoietic stem cell transplant (HSCT)

(This special issue belongs to the Section Molecular Cancer Biology)

Thoracic Malignancies: Diagnosis and Therapy

edited by Avinash Aujayeb

submission deadline 15 Jul 2026 | Viewed by 278 | Submission Open

Keywords: lung cancer; small cell lung cancer; non small cell lung cancer; pleural disease; mesothelioma; screening; chemotherapy; radiotherapy; immunotherapy; palliative care

Advances in First-Line and Second-Line Treatment Research for Renal Cell Carcinoma

edited by

Francesco Ditonno

Celeste Manfredi

and Antonio Franco

submission deadline 15 Jul 2026 | Viewed by 226 | Submission Open

Keywords: renal cell carcinoma; immune checkpoint inhibitors; patient selection; precision medicine; biomarkers

(This special issue belongs to the Section Cancer Therapy)

Thermal Ablation in the Management for Colorectal Liver Metastases: 2nd Edition

edited by

Martijn Meijerink

and

Robbert S. S. Puijk

submission deadline 15 Jul 2026 | Viewed by 221 | Submission Open

Keywords: image-guided therapies; colorectal liver metastases (CRLMs); thermal ablation; (non-)thermal and radiation-related treatment; interventional and radiation oncology

(This special issue belongs to the Section Cancer Metastasis)

Robotic and Laparoscopic Techniques for Urologic Cancers: Innovations in Resection and Reconstruction

edited by

Tobias Klatte

submission deadline 15 Jul 2026 | Viewed by 220 | Submission Open

Keywords: robot-assisted surgery; surgical robotics; minimally invasive surgery; artificial intelligence; complications; prognostic and predictive factors; planning; perioperative care

(This special issue belongs to the Section Methods and Technologies Development)

Views and Perspectives of Robot-Assisted Liver Surgery (2nd Edition)

edited by

Andrew A. Gumbs

and Ibrahim Dagher

submission deadline 16 Jul 2026 | 1 articles | Viewed by 1247 | Submission Open

Keywords: robotic; liver surgery; liver resection; hepatectomy; minimally invasive; artificial intelligence

(This special issue belongs to the Section Cancer Therapy)

Personalizing Head and Neck Cancer Care

edited by

Inge Wegner

and

G. B. Halmos

submission deadline 17 Jul 2026 | 3 articles | Viewed by 3299 | Submission Open

Keywords: head and neck cancer; personalized treatment; targeted therapy; prehabilitation; quality of life

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Skin Cancer: Epidemiology, Management and New Therapies

edited by

Gerardo Cazzato

and Francesco Fortarezza

submission deadline 20 Jul 2026 | 3 articles | Viewed by 11060 | Submission Open

Keywords: skin cancer; melanoma; basal cell carcinoma; squamous cell carcinoma; Merkel cell carcinoma; adnexal tumor; metastatic cutaneous neoplasms; epidemiology; management; therapy

(This special issue belongs to the Section Cancer Therapy)

Current Status and Clinical Developments in Lung Cancer: What to Expect from Emerging Drugs? (2nd Edition)

edited by

Federico Pio Fabrizio

submission deadline 20 Jul 2026 | 1 articles | Viewed by 4713 | Submission Open

Keywords: lung cancer; immunotherapy; immune checkpoint inhibitors (ICIs); target therapy; tyrosine kinase inhibitors (TKIs); cancer biomarkers

(This special issue belongs to the Section Cancer Therapy)

Advances in Early Diagnosis and Minimally Invasive Management in Breast Cancer

edited by

Graziella Di Grezia

submission deadline 20 Jul 2026 | 2 articles | Viewed by 4138 | Submission Open

Keywords: precision medicine; breast cancer prevention; cancer detection; early diagnosis; therapeutic strategies; artificial intelligence; image analysis; risk predictors

(This special issue belongs to the Section Methods and Technologies Development)

HIV-Associated Lymphoid Neoplasms (2nd Edition)

edited by

José-Tomás Navarro

and

Kai Hübel

submission deadline 20 Jul 2026 | 1 articles | Viewed by 919 | Submission Open

Keywords: B-cell lymphoma; HIV; AIDS; Epstein– Barr virus; epidemiology; pathogenesis; prognosis

(This special issue belongs to the Section Infectious Agents and Cancer)

Breaking the Cycle: CDK4/6 Inhibitors Take On Cancers

edited by

Navid Sobhani

submission deadline 20 Jul 2026 | Viewed by 298 | Submission Open

Keywords: CDK4/6 inhibitors; p16; targeted therapy; tumor microenvironment

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Pediatric Liver Cancer Research

edited by Sarah E. Woodfield

submission deadline 20 Jul 2026 | Viewed by 217 | Submission Open

Keywords: hepatoblastoma; pediatric hepatocellular carcinoma; fibrolamellar carcinoma; malignant rhabdoid tumor; undifferentiated embryonal sarcoma; chemotherapy; targeted therapy; immunotherapy; surgery

(This special issue belongs to the Section Pediatric Oncology)

Novel Diagnostic and Therapeutic Approaches in Urologic Oncology

edited by

Whi-An Kwon

submission deadline 21 Jul 2026 | 1 articles | Viewed by 5349 | Submission Open

Keywords: urologic oncology; liquid biopsy; immunotherapy; artificial intelligence; targeted therapy

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Current Advances in Surgical and Systemic Treatment of Breast Cancer

edited by

Kwok-Leung Cheung

and

Srinivasan Madhusudan

submission deadline 23 Jul 2026 | Viewed by 327 | Submission Open

Keywords: breast cancer; breast surgery; oncoplastic surgery; systemic therapy; biomarkers; targeted therapy

(This special issue belongs to the Section Clinical Research of Cancer)

Advances in Exosomes and Cancer Biomarkers

edited by

Nathan Wall

submission deadline 24 Jul 2026 | 3 articles | Viewed by 2907 | Submission Open

Keywords: exosomes; cancer biomarkers; liquid biopsy; tumor microenvironment; molecular diagnosis

(This special issue belongs to the Section Cancer Biomarkers)

Antibodies and Their Derivatives in Cancer Immunotherapy for Gastrointestinal Cancers

edited by

Kiran Kundu

and

Susmita Ghosh

submission deadline 24 Jul 2026 | Viewed by 226 | Submission Open

Keywords: gastrointestinal cancer; immunotherapy; immune checkpoint blocker; monoclonal antibody; CAR; bispecific antibody; T cell engager; NK cell engager

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Image Assisted High Precision Radiation Oncology

edited by Christopher Njeh and Senthamizhchelvan Srinivasan

submission deadline 25 Jul 2026 | 3 articles | Viewed by 2329 | Submission Open

Keywords: image-guided radiation therapy (IGRT); MR-guided radiation therapy (MRgRT); adaptive radiation therapy (ART); radiomics and AI in imaging; multi-modal imaging (CT; MRI; PET); treatment planning and verification; real-time tracking and motion management; stereotactic radiotherapy (SBRT/SRS); imaging biomarkers; dose accumulation and image registration

(This special issue belongs to the Section Methods and Technologies Development)

Updates on Urothelial Carcinoma

edited by

Toyonori Tsuzuki

and Yasmin Abu-Ghanem

submission deadline 25 Jul 2026 | 1 articles | Viewed by 1084 | Submission Open

Keywords: urothelial carcinoma; systemic therapy; molecular biomarkers; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Gene Regulation of Immune Checkpoints in Cancer Immunotherapy

edited by Stamatios Theocharis,

Apostolos Zaravinos

and

Maria-Ioanna Christodoulou

submission deadline 25 Jul 2026 | Viewed by 178 | Submission Open

Keywords: immune checkpoint; gene regulation; immune evasion; epigenetic– immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Neoadjuvant Immunotherapy in Genitourinary Tumors (2nd Edition)

edited by

Antonio Tufano

, Nadia Cordua and

Antonio Giordano

submission deadline 26 Jul 2026 | Viewed by 274 | Submission Open

Keywords: immunotherapy; immune checkpoint inhibitor; bladder cancer; urothelial cancer; kidney cancer; renal cell carcinoma; prostate cancer; testicular cancer; penile cancer; adrenocortical carcinoma

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Advances in Lung Ultrasound in Cancer Patients

edited by Helmut Prosch and

Ehsan Safai Zadeh

submission deadline 30 Jul 2026 | 6 articles | Viewed by 8957 | Submission Open

Keywords: lung ultrasound; neoplastic pleuro-pulmonary lesions; lung cancer; oncologic imaging; ultrasound; CEUS; elastography

(This special issue belongs to the Section Methods and Technologies Development)

Machine Learning and Artificial Intelligence in Cancer Diagnostic and Monitoring

edited by

Junfeng Wang

submission deadline 30 Jul 2026 | 4 articles | Viewed by 6211 | Submission Open

Keywords: machine learning; artificial intelligence; implementation; fairness; uncertainty

(This special issue belongs to the Section Methods and Technologies Development)

Precision Medicine and Targeted Therapies in Neuroblastoma

edited by

Nilay Shah

submission deadline 30 Jul 2026 | 3 articles | Viewed by 4704 | Submission Open

Keywords: pediatric oncology; solid tumors; targeted therapies; biomarkers of response; novel combination therapies; tumor microenvironment; integrative diagnostics; theranostics; telomere maintenance mechanisms; neuroblastoma

(This special issue belongs to the Section Clinical Research of Cancer)

Cancer Pain: Advances in Pathophysiology and Management

edited by

Giustino Varrassi

and

Matteo Luigi Giuseppe Leoni

submission deadline 30 Jul 2026 | 1 articles | Viewed by 3813 | Submission Open

Keywords: cancer pain; mixed pain; pathophysiology; sensitization; multimodal analgesia; interventional management

Ovarian Cancer: Pathogenesis, Molecular Mechanism and Opportunities for Interventions

edited by

Apriliana Kartikasari

submission deadline 30 Jul 2026 | 1 articles | Viewed by 2779 | Submission Open

Keywords: ovarian cancer; pathogenesis; therapy; biomarkers; molecular

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Multidisciplinary Approach to Bladder Cancer Treatment and Care

edited by Bente Thoft Jensen and

Susanne Vahr Lauridsen

submission deadline 30 Jul 2026 | 3 articles | Viewed by 2190 | Submission Open

Keywords: non-muscle-invasive bladder cancer; muscle-invasive bladder cancer; health-related quality of life; nutrition; prehabilitation; sexual health; nursing leadership; implementation; new technologies

(This special issue belongs to the Section Cancer Therapy)

The Evolution of Minimally Invasive Surgery in Hepatobiliary Pancreatic Cancers

edited by Asmus Heumann

submission deadline 30 Jul 2026 | 1 articles | Viewed by 704 | Submission Open

Keywords: minimally invasive surgery; biliary tract cancer; perhilar carcinoma; pancreatic cancer; liver transplantation

(This special issue belongs to the Section Cancer Therapy)

Cutting-Edge Nanomedicine Advancements in Cancer Disease

edited by

Ana Isabel Torres-Suárez

and

Ana Isabel Fraguas-Sánchez

submission deadline 30 Jul 2026 | Viewed by 498 | Submission Open

Keywords: active targeting; breast cancer; drug delivery; liposomes; lung cancer; metallic nanoparticles; polymeric nanoparticles; theragnostic

(This special issue belongs to the Section Methods and Technologies Development)

Flow Cytometry and Molecular Studies in Hematological Malignancies

edited by Kirill A. Lyapichev

submission deadline 30 Jul 2026 | Viewed by 398 | Submission Open

Keywords: flow cytometry; molecular studies; hematological neoplasms; lymphoma; leukemia

(This special issue belongs to the Section Molecular Cancer Biology)

Cellular Plasticity, Metabolic Adaptations and Therapeutic Strategies in Breast Cancer

edited by

Kunwar Somesh Vikramdeo

submission deadline 30 Jul 2026 | Viewed by 391 | Submission Open

Keywords: breast cancer; cellular plasticity; metabolic reprogramming; tumor microenvironment; therapy resistance; epithelial– mesenchymal transition (EMT); cancer stem cells; redox metabolism; mitochondrial pathways; targeted therapy

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Surgical Management of Ovarian Cancer

edited by Lina Salman

submission deadline 30 Jul 2026 | Viewed by 296 | Submission Open

Keywords: ovarian cancer; surgical management; complications; HIPEC; survival

(This special issue belongs to the Section Clinical Research of Cancer)

Resection and Reconstruction for Breast Cancer

edited by Radoslaw Tarkowski and

Gilles Houvenaeghel

submission deadline 30 Jul 2026 | Viewed by 266 | Submission Open

Keywords: oncoplastic breast surgery; breast reconstruction; breast cancer

(This special issue belongs to the Section Clinical Research of Cancer)

The New Era of Esophageal Cancer Treatment: Advances in Combination Therapy

edited by

Elena Mazza

submission deadline 30 Jul 2026 | Viewed by 211 | Submission Open

Keywords: esophageal cancer; combination therapy; immunotherapy; targeted agents; Pd-L1; chemotherapy; radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Advancements in Preclinical Models for Solid Cancers

edited by

Ewa Krawczyk

and Paula Dobosz

submission deadline 31 Jul 2026 | 11 articles | Viewed by 24424 | Submission Open

Keywords: solid cancers; preclinical cancer models; in vitro cancer models; in vivo cancer models; translational cancer research; strengths and limitations of preclinical cancer models

(This special issue belongs to the Section Clinical Research of Cancer)

Emerging Research on Primary Brain Tumors

edited by Jacob S Young and Mitchel S. Berger

submission deadline 31 Jul 2026 | 6 articles | Viewed by 24396 | Submission Open

Keywords: molecular biomarkers; drug delivery; immunotherapy; personalized medicine; targeted therapies; glioma

(This special issue belongs to the Section Cancer Therapy)

Systematic Reviews and Meta-Analyses of Genitourinary Cancers (2nd Edition)

edited by

Giorgio Treglia

and Ursula Maria Vogl

submission deadline 31 Jul 2026 | 6 articles | Viewed by 21307 | Submission Open

Keywords: systematic review; meta-analysis; oncology; genitourinary cancers; diagnosis; therapy

(This special issue belongs to the Section Systematic Review or Meta-Analysis in Cancer Research)

Displaying special issue 251-300 on page 6 of 25.

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