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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Prospect of Nanobiotechnology in Cancers
edited by
submission deadline 20 Jan 2026 | Viewed by 158 | Submission Open
Keywords: nanobiotechnology; cancer therapy; targeted drug delivery; tumor microenvironment
(This special issue belongs to the Section Methods and Technologies Development)
Recent Updates on Imaging and Staging of Gynecologic Cancers
edited by and Alexander B. Olawaiye
submission deadline 21 Jan 2026 | 2 articles | Viewed by 2392 | Submission Open
Keywords: imaging; surgical staging; molecular prognostic features; mortality; prognosis
(This special issue belongs to the Section Methods and Technologies Development)
Roles of the Tumor Microenvironment on Liquid Biopsy (2nd Edition)
edited by
submission deadline 22 Jan 2026 | Viewed by 313 | Submission Open
Keywords: liquid biopsy; CTCs; CTC characterization and CTC clustering; ctDNA and ctDNA profiling; exosomes/extracellular vesicles and biology; tumor microenvironment; bone marrow cellular/molecular heterogeneity; CTCs/blood/BM cells crosstalk; analytical validity; clinical validity; and clinical utility of liquid biopsy; liquid biopsy interplaying dormancy and metastasis
(This special issue belongs to the Section Tumor Microenvironment)
Advancements in Salivary Gland Tumors Management: From Diagnostic Imaging to Treatment Strategies
edited by Wioletta Pietruszewska, Małgorzata Wierzbicka and
submission deadline 22 Jan 2026 | Viewed by 233 | Submission Open
Keywords: salivary gland tumors; MRI; CT; and PET; minimally invasive approaches
(This special issue belongs to the Section Cancer Therapy)
Innovative Immunotherapies: CAR-T Cell Therapy for Cancers: 2nd Edition
edited by
submission deadline 23 Jan 2026 | 3 articles | Viewed by 6172 | Submission Open
Keywords: CAR-T; NK-CAR; immunotherapy; cancer; resistance mechanisms
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Targeting Hallmarks of Cancer submission deadline 25 Jan 2026 | Viewed by 725 | Submission Open
Keywords: epigenetic regulators; organotypic culture models; anticancer drugs; hallmarks of cancer
(This special issue belongs to the Section Cancer Biomarkers)
Towards a Personalized Medicine for the Diagnosis and Management of Gynecological Cancers
edited by and Gabriele Centini
submission deadline 30 Jan 2026 | 3 articles | Viewed by 20112 | Submission Open
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
The Advance of Pencil Beam Scanning Proton Beam Therapy in Cancers
edited by , Richard A. Amos and Heng Li
submission deadline 30 Jan 2026 | 7 articles | Viewed by 15489 | Submission Open
Keywords: proton therapy; pencil beam scanning; robustness; adaptive radiotherapy; imaging guidance; radiobiological model; FLASH radiotherapy; spatially fractionated radiotherapy (SFRT); proton arc
(This special issue belongs to the Section Cancer Therapy)
Cancer Disparities: Biological, Social, and Environmental Determinants submission deadline 30 Jan 2026 | 3 articles | Viewed by 5957 | Submission Open
Keywords: cancer epidemiology; cancer etiology; environmental factors; screening and diagnostics; SDGs
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in the Treatment of Upper Gastrointestinal Cancer
edited by Sang-ho Jeong and
submission deadline 30 Jan 2026 | 2 articles | Viewed by 4610 | Submission Open
Keywords: upper gastrointestinal cancer; surgery therapy; chemotherapy therapy; radiation therapy
(This special issue belongs to the Section Cancer Therapy)
Protein Structure and Cancer—2nd Edition submission deadline 30 Jan 2026 | Viewed by 189 | Submission Open
Keywords: protein structure dynamics; structural cancer biology; protein pathways in cancer; structure– function alterations; in silico protein structure prediction; protein interactions; cancer mutations and protein structure alterations
(This special issue belongs to the Section Molecular Cancer Biology)
Metastasis in Tumor Immunity: Current Perspectives
edited by , Sebastian Torke and
submission deadline 30 Jan 2026 | Viewed by 184 | Submission Open
Keywords: immune escape; immune evasion; immune microenvironment; intervention strategies; senescence on metastasis; anti-tumor immunity; cellular interactions; molecular interactions; immune suppression; immune checkpoints
(This special issue belongs to the Section Cancer Metastasis)
Advances in Drug Delivery for Cancer Therapy submission deadline 31 Jan 2026 | 9 articles | Viewed by 37711 | Submission Open
Keywords: cancer; oncology; therapeutic target; drug resistance; immunotherapy; chemotherapy; small molecule inhibitors; drug delivery; nanoparticle
(This special issue belongs to the Section Cancer Drug Development)
How COVID-19 Affects Cancer Patients
edited by
submission deadline 31 Jan 2026 | 15 articles | Viewed by 34140 | Submission Open
Keywords: COVID-19; pandemic; cancer; impact; incidence; mortality; lethality; disparities; gender
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Surgical Advances in Cancer Treatments: Exploring Innovative Approaches and Emerging Perspectives submission deadline 31 Jan 2026 | 16 articles | Viewed by 29978 | Submission Open
Keywords: surgical oncology; surgical innovation; image-guided surgery; robotic-assisted surgery; multidisciplinary oncology; surgical outcomes research; precision surgery; healthcare economics; surgical training and simulation
(This special issue belongs to the Section Cancer Therapy)
Genetics and Epigenetics of Gynecological Cancer
edited by
submission deadline 31 Jan 2026 | 10 articles | Viewed by 28856 | Submission Open
Keywords: gynecologic cancers; epigenetics; genetics; immunogenetics; predisposing mutations; biomarkers; targeted therapies; chemoresistance
(This special issue belongs to the Section Cancer Pathophysiology)
CAR T Cells in Lymphoma and Multiple Myeloma submission deadline 31 Jan 2026 | 7 articles | Viewed by 22708 | Submission Open
Keywords: multiple myeloma; lymphoma; CAR T therapy; bi-specific antibodies; cellular therapy
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Screening, Early Detection and Prevention of Hepato-Pancreato-Biliary (HPB) Cancers
edited by Zaed Z.R. Hamady
submission deadline 31 Jan 2026 | 7 articles | Viewed by 22059 | Submission Open
Keywords: hepatobiliary cancer; pancreatic cancer; early detection; diagnosis; screening; prevention
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Emerging Research on Primary Brain Tumors
edited by Jacob S Young and Mitchel S. Berger
submission deadline 31 Jan 2026 | 6 articles | Viewed by 15857 | Submission Open
Keywords: molecular biomarkers; drug delivery; immunotherapy; personalized medicine; targeted therapies; glioma
(This special issue belongs to the Section Cancer Therapy)
Thyroid Cancer: Diagnosis, Prognosis and Treatment (2nd Edition) submission deadline 31 Jan 2026 | 8 articles | Viewed by 15449 | Submission Open
Keywords: thyroid cancer; ultrasound; molecular imaging; fine-needle aspiration cytology; thyroidectomy; radioactive iodine; radioiodine-refractory thyroid cancer; tyrosine kinase inhibitors
(This special issue belongs to the Section Cancer Therapy)
Empowering Cancer Survivors: A Comprehensive Approach to Supportive Care Through Pharmacological and Non-Pharmacological Approaches Including Exercise, Physical Activity and Nutrition
edited by Kellie Toohey
submission deadline 31 Jan 2026 | 10 articles | Viewed by 12733 | Submission Open
Keywords: cancer; physical activity; exercise; supportive care; holistic care; rehabilitation
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Pathology and Treatment of Triple-Negative Breast Cancer
edited by
submission deadline 31 Jan 2026 | 4 articles | Viewed by 11550 | Submission Open
(This special issue belongs to the Section Cancer Pathophysiology)
Implementation of Physical Activity Promotion in Cancer Care
edited by Sarah Hardcastle
submission deadline 31 Jan 2026 | 4 articles | Viewed by 10079 | Submission Open
Keywords: physical activity; cancer survivors; behaviour change; interventions; cancer care; implementation; health
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
The Tumor Microenvironment: Interplay Between Immune Cells
edited by Jared Rowe and Kristen E. Pauken
submission deadline 31 Jan 2026 | 5 articles | Viewed by 9512 | Submission Open
Keywords: tumor immune microenvironment; metabolic microenvironment; immune cells
(This special issue belongs to the Section Tumor Microenvironment)
Recent Advances and Challenges in Breast Cancer Surgery: 2nd Edition submission deadline 31 Jan 2026 | 6 articles | Viewed by 8023 | Submission Open
Keywords: breast cancer surgery; axillary management; sentinel node oncoplastic surgery; reconstructive surgery; surgical technology; cancer risk reduction surgery; radio-guided surgery
(This special issue belongs to the Section Cancer Therapy)
Recent Advances in Oncology Imaging: 2nd Edition
edited by and
submission deadline 31 Jan 2026 | 4 articles | Viewed by 7580 | Submission Open
Keywords: medical imaging; cancer; oncology; molecular imaging; theragnostics
(This special issue belongs to the Section Methods and Technologies Development)
Biomarkers and Targeted Therapy in Malignant Pleural Mesothelioma
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 5575 | Submission Open
Keywords: malignant mesothelioma; target therapy; biomarkers
(This special issue belongs to the Section Cancer Biomarkers)
The Role of Apoptosis and Autophagy in Cancer
edited by
submission deadline 31 Jan 2026 | 3 articles | Viewed by 4816 | Submission Open
Keywords: apoptosis; cell death; tumor
(This special issue belongs to the Section Molecular Cancer Biology)
Exploring Skin Cancer: Insights into New Diagnostic, Prognostic, and Therapeutic Strategies
edited by
submission deadline 31 Jan 2026 | 4 articles | Viewed by 4779 | Submission Open
Keywords: melanoma; non-melanoma skin cancer; NMSC; Merkel cell carcinoma; tumor microenvironment; prognosis; treatment
Cancer Screening and Primary Care
edited by Marievelisse Soto-Salgado
submission deadline 31 Jan 2026 | 5 articles | Viewed by 4699 | Submission Open
Keywords: screening amenable cancers; screening; primary care; disparities in cancer care; cancer outcomes
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in Lung Ultrasound in Cancer Patients
edited by Helmut Prosch and
submission deadline 31 Jan 2026 | 4 articles | Viewed by 4560 | Submission Open
Keywords: lung ultrasound; neoplastic pleuro-pulmonary lesions; lung cancer; oncologic imaging; ultrasound; CEUS; elastography
(This special issue belongs to the Section Methods and Technologies Development)
Oral Cancer: The Latest Advances in Clinical and Basic Research (Second Edition)
edited by and Fumihiko Uchida
submission deadline 31 Jan 2026 | 4 articles | Viewed by 4247 | Submission Open
Keywords: oral cancer; clinical research; basic research; surgery; radiotherapy; chemotherapy; molecular biology; immune checkpoint inhibitor
(This special issue belongs to the Section Clinical Research of Cancer)
Prediction of Melanoma
edited by
submission deadline 31 Jan 2026 | 3 articles | Viewed by 3934 | Submission Open
Keywords: melanoma; melanoma genetics; biomarkers; predictive tools; risk prediction; risk factors; artificial intelligence
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Clinical Studies and Outcomes in Urologic Cancer
edited by Nikolaos Pyrgidis
submission deadline 31 Jan 2026 | 3 articles | Viewed by 3724 | Submission Open
Keywords: urologic cancer; clinical outcomes; prostate cancer; urothelial cancer; kidney cancer; survival analysis; treatment response; quality of life; novel therapies; oncology
(This special issue belongs to the Section Clinical Research of Cancer)
Recent Advances in Nanomedicine-Based Cancer Immunotherapy
edited by Navin Kumar Verma, and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 2853 | Submission Open
Keywords: cancer nano-therapy; nano-enabled therapeutic; immune checkpoint inhibitors; tumor immunosuppression; adoptive cell therapy; CAR T-cell therapy; tumor-infiltrating lymphocyte therapy; monoclonal antibody therapy for cancer; cancer vaccines; immune system modulators
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Minimally Invasive Approaches in Urological Oncology: Current Trends and Innovations submission deadline 31 Jan 2026 | 3 articles | Viewed by 2764 | Submission Open
Keywords: minimally invasive; robotic; laparoscopic; uro-oncology; prostate cancer; bladder cancer; kidney cancer; testicular cancers; quality of life; penile cancer
(This special issue belongs to the Section Clinical Research of Cancer)
Computational Research in Cancer Neuroscience
edited by Shaolei Teng
submission deadline 31 Jan 2026 | 1 articles | Viewed by 2685 | Submission Open
Keywords: machine learning; large language models; protein structure modeling; omics data analysis; neural– cancer communication; tumor microenvironments; personalized medicine; targeted therapies; cancer neuroscience
(This special issue belongs to the Section Methods and Technologies Development)
Post-Neoadjuvant Strategies in Breast Cancer (2nd Edition)
edited by , Tanja Fehm and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 2325 | Submission Open
Keywords: chemotherapy; prospective trials; clinical investigation; breast tumor; local recurrence; overall survival
(This special issue belongs to the Section Cancer Therapy)
Novel Perspectives in Hepato-Biliary and Pancreatic Cancer
edited by Tudor Mocan and Emil-Ioan Moiș
submission deadline 31 Jan 2026 | 2 articles | Viewed by 2135 | Submission Open
Keywords: HCC; cholangiocarcinoma; surgery; biliary drainage; pancreatic cancer; combination therapies
(This special issue belongs to the Section Cancer Therapy)
Advances and Future Developments in Liver Transplantation for Cancers: 2nd Edition
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 2048 | Submission Open
Keywords: machine perfusion; marginal graft; split liver; immunotherapy; auxiliary liver transplantation; digital twin; modeling; organoid
(This special issue belongs to the Section Transplant Oncology)
Cancers Hijack Immune Surveillance and Tumor Microenvironment Leading to Immune Evasion
edited by , Viktor Umansky and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1914 | Submission Open
Keywords: anti-tumor immunity; cancer immunotherapy; immune evasion; immune response modulation; immunosuppression; immune surveillance; manipulating IR components function and migration; metabolic modulation of the TME; metabolic reprogramming; tumor-associated immune cells; tumor microenvironment (TME)
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Head and Neck Cancer: Survivorship Challenges and Therapeutic Approaches
edited by , Avraham Eisbruch and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1798 | Submission Open
Keywords: head and neck cancer; supportive care; survivorship care; physiotherapy; quality of life; lifestyle interventions
(This special issue belongs to the Section Cancer Therapy)
Clinical Trials and Outcomes for Non-Small Cell Lung Cancer submission deadline 31 Jan 2026 | 2 articles | Viewed by 1588 | Submission Open
Keywords: non-small cell lung cancer; oncogenic alterations; clinical trial; systemic therapy; targeted therapy; immunotherapy; radiotherapy; real-world data; surgery; drug development
(This special issue belongs to the Section Clinical Research of Cancer)
Radiosensitivity and Radiotoxicity in Cancer submission deadline 31 Jan 2026 | 1 articles | Viewed by 1528 | Submission Open
Keywords: radiation therapy; clinical outcome; radiosensitivity; radiotoxicity; biomarkers; bioinformatics; systems biology
(This special issue belongs to the Section Methods and Technologies Development)
Advanced Strategies in the Care of Hepatocellular Carcinoma Patients (2nd Edition) submission deadline 31 Jan 2026 | 1 articles | Viewed by 1380 | Submission Open
Keywords: hepatocellular carcinoma; hepatic resection; hepatectomy; liver resection; liver surgery; parenchymal-sparing liver surgery; intraoperative ultrasound; liver-specific magnetic resonance imaging; trans-arterial therapy; liver function; FibroScan
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Advanced Glycation End-Products and Its Receptors in Cancer Progression
edited by Bhaumik B. Patel
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1366 | Submission Open
Keywords: advanced glycation end products; toxic advanced glycation end products; receptor for advanced glycation end products (RAGEs); glycosaminoglycans; cancer; cancer stem cells (CSCs); tumor immune microenvironment (TME)
(This special issue belongs to the Section Tumor Microenvironment)
Nutrition in Survivors with Advanced Cancer: The Role of Appetite, Muscle Wasting, Obesity, and Altered Body Composition
edited by Egidio Del Fabbro
submission deadline 31 Jan 2026 | 1 articles | Viewed by 867 | Submission Open
Keywords: advanced cancer; nutrition; wasting; body composition; multimodal
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Novel Approaches in the Management of Gynecological Cancers submission deadline 31 Jan 2026 | 1 articles | Viewed by 710 | Submission Open
Keywords: gynecological cancer; ovarian cancer; endometrial cancer; cervical cancer; vulvar cancer; surgical management; clinical management
(This special issue belongs to the Section Cancer Therapy)
Emerging Technologies in Thoracic Surgery
edited by Filippo Lococo and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 706 | Submission Open
Keywords: lung cancer; molecular biology; liquid biopsy; immunotherapy; precision surgery; minimally invasive surgery; new technologies; artificial intelligence
(This special issue belongs to the Section Methods and Technologies Development)
Updates on Imaging of Common Urogenital Neoplasms 2nd Edition
edited by Athina C Tsili
submission deadline 31 Jan 2026 | 1 articles | Viewed by 691 | Submission Open
Keywords: urogenital neoplasms; renal cell carcinoma; prostatic neoplasms; urinary bladder neoplasms; testicular neoplasms; uterine neoplasms; ovarian neoplasms; ultrasonography; computed tomography; magnetic resonance imaging
(This special issue belongs to the Section Methods and Technologies Development)
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