Personalizing Head and Neck Cancer Care

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Survivorship and Quality of Life".

Deadline for manuscript submissions: 17 July 2026

Special Issue Editors


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Guest Editor
Department of Otorhinolaryngology and Head and Neck Surgery, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
Interests: head and neck cancer; personalized treatment; shared decision making; prehabilitation; prediction; frailty; targeted therapy; surgery

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Guest Editor
Department of Otorhinolaryngology—Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Interests: head and neck oncology; geriatric oncology; sarcopenia; health care pathway
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Special Issue Information

Dear Colleagues, 

An important development in head and neck cancer research lies in personalizing cancer care. Patients with head and neck cancer are at high risk of physical, functional, and psychosocial deterioration and are thus considered vulnerable. They are at high risk of malnutrition, are often sarcopenic, and are generally frailer than patients with other solid malignancies. Identifying frail patients suitable for complex treatments or requiring treatment adaptation is paramount. 

Prediction models and intervention trials aid us in shared decision-making and individualizing treatment. Shared decision-making models are rising in prominence and enable patients to play an active role in shaping their treatment plans. Models should not only address physical aspects of well-being but also functional aspects and overall and disease-specific quality of life. 

Advances in personalized treatment strategies include targeted therapies, immunotherapy, and adaptive radiation techniques, as well as prehabilitation programs addressing nutrition, physical exercise, and psychosocial interventions. 

Lastly, innovations in monitoring head and neck cancer help to personalize follow-up. Developments include tumor mutational burden and circulating tumor DNA, as well as the use of telecommunication and telemedicine. 

Dr. Inge Wegner
Dr. G. B. Halmos
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • head and neck cancer
  • personalized treatment
  • targeted therapy
  • prehabilitation
  • quality of life

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This special issue is now open for submission.
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