Advancements in Preclinical Models for Solid Cancers
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Clinical Research of Cancer".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 393
Special Issue Editors
Interests: cancer research; cell conditional reprogramming; in vitro models; preclinical disease models; cell culture; rare cancers; HPV; kidney disease
Special Issue Information
Dear Colleagues,
We are pleased to introduce and invite you to a Special Issue that is focused on the latest developments in preclinical modeling of various types of solid cancers. Cancer is a major health burden globally and one of the leading causes of death worldwide. There is an urgent need for novel and effective preclinical methods, both in vitro and in vivo, that can model the disease at any stage, including primary and metastatic cancers. New advanced preclinical models can aid in cancer diagnosis, drug screening and development, and personalized treatment strategies.
Cancer research currently depends on reliable preclinical models that are commonly used in all areas of basic and translational research, including studies on mechanisms of tumorigenesis, the cancer microenvironment, metastasis, molecular biology, structural biology, epigenetics, medicinal chemistry, and precision medicine, to name but a few. However, no preclinical model is ideal and all of them have various limitations to a lesser or greater extent. Thus, there is an urgent need for the development of new models that recapitulate particular stages of various solid cancers and closely resemble pathology and the course of these malignancies in humans.
This Special Issue aims to collect manuscripts describing advances in the development of preclinical models that can provide valuable information for researchers and clinicians strategizing new therapeutic/diagnostic approaches. Original research articles and reviews are both welcome. Research areas may include (but are not limited to) the following:
- Recent advances in preclinical cancer models for solid cancers;
- Development and implementation of patient-derived models for solid cancers;
- Preclinical solid cancer models as a tool in precision and personalized medicine.
I look forward to receiving your contributions.
Dr. Ewa Krawczyk
Dr. Paula Dobosz
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- solid cancers
- preclinical cancer models
- in vitro cancer models
- in vivo cancer models
- translational cancer research
- strengths and limitations of preclinical cancer models
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