Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section
Search by Title/Keyword
 
Order results
Display
Results per page
Zebrafish Models in Cardiovascular and Metabolic Precision Medicine submission deadline 7 Nov 2025 | Viewed by 198 | Submission Open
Keywords: zebrafish models; cardiovascular disease; metabolic disorders; precision medicine; genetic screening; drug discovery; disease modeling; translational research; personalized therapy; high-throughput screening
Protein Structure Prediction in Drug Discovery: 2nd Edition submission deadline 15 Nov 2025 | 6 articles | Viewed by 31585 | Submission Open
Keywords: protein structure prediction; drug design; docking; virtual screening; drug discovery; machine learning; alphafold
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Advances in Neuroproteomics submission deadline 15 Nov 2025 | 10 articles | Viewed by 29574 | Submission Open
Keywords: discovery mass spectrometry; neuroproteomics; mass spectrometry; quantitative proteomics; targeted mass spectrometry
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Interface of Aging and Biomaterials: 2nd Edition
edited by
submission deadline 15 Nov 2025 | 3 articles | Viewed by 13568 | Submission Open
Keywords: aging; senescence; geroscience; biomolecules; biomaterials; biocompatibility; nanoparticles; hydrogels
(This special issue belongs to the Section Bio-Engineered Materials)
Recent Advances in Mass Spectrometry-Based Proteomics
edited by and Simon Devos
submission deadline 15 Nov 2025 | Viewed by 177 | Submission Open
Keywords: LC-MS/MS proteomics; high-throughput; low input proteomics; clinical proteomics; spatial proteomics; immunopeptidomics; post-translational protein modifications; biomarker discovery; drug targets
(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)
Structural Proteomics–Structural Biology Led by Advancements in Mass Spectrometry Techniques
edited by , Corie Ralston and
submission deadline 20 Nov 2025 | 2 articles | Viewed by 7682 | Submission Open
Keywords: hydroxyl radical protein footprinting MS (XFP; FPOP); hydrogen/deuterium exchange MS (HDX-MS); cross-linking MS (XL-MS); covalent labeling MS; top-down MS; native MS
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Advances in the Structure and Function of Microtubule-Associated Motor Proteins
edited by Arne Gennerich
submission deadline 20 Nov 2025 | 1 articles | Viewed by 1561 | Submission Open
Keywords: microtubules; kinesin; dynein; CryoEM; post-translational modifications
(This special issue belongs to the Section Molecular Biophysics: Structure, Dynamics, and Function)
Design and Synthesis of Bioactive Compounds for Therapeutic Applications submission deadline 30 Nov 2025 | 11 articles | Viewed by 21038 | Submission Open
Keywords: drug design and discovery; synthesis of bioactive molecules; biological evaluations and applications; diagnostics; drug delivery
(This special issue belongs to the Section Natural and Bio-derived Molecules)
New Insights into Integrins
edited by
submission deadline 30 Nov 2025 | 6 articles | Viewed by 17732 | Submission Open
Keywords: integrins; growth factors; ligands
(This special issue belongs to the Section Biological Factors)
Experimental and Theoretical Approaches to Protein-Targeting Drug Discovery: 2nd Edition submission deadline 30 Nov 2025 | 6 articles | Viewed by 15442 | Submission Open
Keywords: proteins; peptides; amyloid; aptamers; molecular docking; Alzheimer disease; Parkinson’ s disease; neurodrugs; biotechnological enzymes; antiviral drugs; vaccines; biomolecular targets; COVID-19; SARS-CoV-2; spike protein; peptide aggregation; drug repurposing; natural products; synthetic antivirals; anticancer therapeutics
(This special issue belongs to the Section Chemical Biology)
Molecular Aspects of Female Infertility
edited by
submission deadline 30 Nov 2025 | 6 articles | Viewed by 13267 | Submission Open
Keywords: female infertility; reproduction; ovary; reproductive aging; genetic disorders
(This special issue belongs to the Section Molecular Biology)
Advances in p53 Research submission deadline 30 Nov 2025 | 3 articles | Viewed by 12504 | Submission Open
Keywords: p53; small molecules; tumor suppressor; apoptosis; tumor– host interaction; targeted therapies; tumor microenvironment (TME)
(This special issue belongs to the Section Molecular Biology)
Colorectal and Gastric Cancers: Molecular Mechanisms and Potential Biomarkers submission deadline 30 Nov 2025 | 6 articles | Viewed by 11105 | Submission Open
Keywords: colorectal cancer; gastric cancer; molecular mechanism; biomarkers signalling; molecules gastrointestinal; microbiome; artificial intelligence
(This special issue belongs to the Section Molecular Biomarkers)
The Role of Mechanotransduction in Cellular Biology submission deadline 30 Nov 2025 | 3 articles | Viewed by 8939 | Submission Open
Keywords: cell membrane; cytosol; nuclear membrane; integrin; mechanotransduction; map kinase pathway; ERKs; JNKs; p38/SAPKs; YAP/TAZ; Hippo pathway
(This special issue belongs to the Section Cellular Biochemistry)
Skeletal Muscle in Health, Exercise and Aging
edited by Barbara Munz
submission deadline 30 Nov 2025 | 3 articles | Viewed by 8610 | Submission Open
Keywords: skeletal muscle; molecular mechanisms of exercise adaptation; aging; cachexia; sarcopenia
(This special issue belongs to the Section Molecular Biology)
Microbial Biocontrol and Plant-Microbe Interactions
edited by
submission deadline 30 Nov 2025 | 6 articles | Viewed by 7949 | Submission Open
Keywords: endophytic microbiome for disease management; plant– microbe interactions; plant– insect– pathogen interactions; microbial and plant metabolites against pathogens; pathogen signaling; microbial communities shift for disease prevention; omics approaches; abiotic stress response
(This special issue belongs to the Section Cellular Biochemistry)
Mass Spectrometry Imaging in Neuroscience
edited by Nhu Thi Ngoc Phan
submission deadline 30 Nov 2025 | 2 articles | Viewed by 5048 | Submission Open
Keywords: mass spectrometry imaging; secondary ion mass spectrometry (SIMS); matrix-assisted laser desorption/ionization (MALDI); desorption electrospray ionization (DESI); laser ablation– inductively coupled plasma– mass spectrometry imaging (LA-ICP-MSI); multi-isotope imaging mass spectrometry (MIMS); molecular and organelle turnover; brain; neurons; synapses; neuronal stem cells; membrane lipids; synaptic proteins; neural peptides; metabolites; diseases; disorders
(This special issue belongs to the Section Molecular Medicine)
Metabolic Inflammation and Insulin Resistance in Obesity
edited by Bingxian Xie
submission deadline 30 Nov 2025 | 2 articles | Viewed by 4652 | Submission Open
Keywords: obesity-linked inflammation; insulin resistance; adipose tissue
(This special issue belongs to the Section Lipids)
Properties and Functions of Endometrial Stromal Cells submission deadline 30 Nov 2025 | 2 articles | Viewed by 4299 | Submission Open
Keywords: endometrium; endometriosis; molecular reproduction; implantation; decidualization; placentation; inflammation; reproductive endocrinology; assisted reproductive technology; molecular reproductive biology
(This special issue belongs to the Section Molecular Reproduction)
Molecular Advances in Platelet Disease, Thrombosis and Hemostasis
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 4179 | Submission Open
Keywords: platelets; hemostasis and thrombosis; inherited platelet disorders; coagulation; immunothrombosis; miRNA; GPVI; Runx1; antiplatelet therapy
(This special issue belongs to the Section Molecular Biology)
Advances in Cancer and Glycosylation
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 3740 | Submission Open
Keywords: glycosylation; glycobiology; N-glycans; O-glycans; glycosyltransferases; glycosidases
(This special issue belongs to the Section Molecular Medicine)
Recent Advances in Cellular and Non-Cellular Treatment of Stroke
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 3692 | Submission Open
Keywords: stroke; treatment; therapy; biomolecules; stem cells
(This special issue belongs to the Section Molecular Medicine)
Tumor Microenvironment, Immunology and Precision Medicine of Liver Cancer
edited by Lynn Jeanette Savic
submission deadline 30 Nov 2025 | 2 articles | Viewed by 3677 | Submission Open
Keywords: hepatocellular carcinoma; hypoxia; tumor microenvironment; immunometabolic crosstalk; tumor-associated macrophages
(This special issue belongs to the Section Biological Factors)
New Insights into Neuroimmunology submission deadline 30 Nov 2025 | 1 articles | Viewed by 3647 | Submission Open
Keywords: neuroimmunology (in health and disease); multiple sclerosis (MS); experimental autoimmune encephalomyelitis (EAE); acute disseminated encephalomyelitis (ADEM); neuromyelitis optica spectrum disorders (NMOSD); transverse myelitis; anti-NMDA receptor encephalitis (NMDAR encephalitis); paraneoplastic autoimmune diseases; neurodegenerative diseases with immunological components; Parkinson’ s disease; Alzheimer’ s disease; neuroinfections
(This special issue belongs to the Section Cellular Biochemistry)
Antioxidant and Anti-Inflammatory Activities of Phytochemicals
edited by and
submission deadline 30 Nov 2025 | 2 articles | Viewed by 2649 | Submission Open
Keywords: antioxidants; plant bioactives; inflammation; free radicals
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Recent Developments in the Biology of Extracellular or Cell-Free DNA, 2nd Edition
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2295 | Submission Open
Keywords: neutrophil extracellular traps; DNase; toll-like receptor 9; exosomes; autoimmunity
(This special issue belongs to the Section Molecular Biology)
Advances in Nano-Based Drug Delivery Systems submission deadline 30 Nov 2025 | 2 articles | Viewed by 2259 | Submission Open
Keywords: drug delivery system; nanotechnology; nanomedicine; nanocarriers; nanoparticles; nanoformulation; biomolecules
(This special issue belongs to the Section Molecular Medicine)
Pluripotent Stem Cell Models of Human Disease
edited by Satish Kumar
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2106 | Submission Open
Keywords: pluripotent stem cells; cellular reprogramming; cellular differentiation; 2D and 3D cell models of human disease; cellular phenotypes; biomarkers; disease gene; multi-omics approaches; genome editing; drug screening and discovery
(This special issue belongs to the Section Cellular Biochemistry)
Impact of Exercise Physiology and Diet on Adipokines in Health and Diseases
edited by Aurora Daniele and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2066 | Submission Open
Keywords: adipose tissue; adiponectin; adiponectin receptors; physical exercise; exercise; health; disease
(This special issue belongs to the Section Biological Factors)
New Insights into Cardiometabolic Diseases, 2nd Edition
edited by and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1938 | Submission Open
Keywords: metabolic diseases; hypertension; obesity; type-2 diabetes; vascular diseases; acute vascular events
(This special issue belongs to the Section Molecular Medicine)
Biomolecules and Materials from Agro-Industrial Wastes, 2nd Edition submission deadline 30 Nov 2025 | 1 articles | Viewed by 1742 | Submission Open
Keywords: bioactive molecules from discarded plant parts; new extraction methodologies; green solvents; green chemistry; bioenergy; biorefinery; biofibres
(This special issue belongs to the Section Bio-Engineered Materials)
Industrial Microorganisms and Enzyme Technologies
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 1671 | Submission Open
Keywords: enzyme engineering; enzyme kinetics and optimization; industrial biotechnology; industrial microbiology; microbial metabolism
(This special issue belongs to the Section Enzymology)
New Insights into Stem Cell-Derived Exosomes in Human Health and Disease
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1634 | Submission Open
Keywords: stem cells; exosomes; regenerative medicine; diagnostics
(This special issue belongs to the Section Cellular Biochemistry)
Protein Self-Assembly in Diseases and Function
edited by , Srivastav Ranganathan and Maria del Carmen Fernandez Ramirez
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1497 | Submission Open
Keywords: protein folding; protein aggregation; amyloids; biomolecular condensates
(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)
Defects in the Transport Mechanism of Membrane Proteins and Related Diseases, 2nd Edition
edited by Daniela Valeria Miniero
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1402 | Submission Open
Keywords: function; structure and folding of membrane transport proteins; pathological mutations; mechanism of transport; neurological and metabolic disease; transport of nanoparticles; organelle membranes; cellular function and signaling; bioenergetics; neuroinflammation; nanoformulations for drug targets
(This special issue belongs to the Section Cellular Biochemistry)
Acute Kidney Injury and Mitochondrial Involvement
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1282 | Submission Open
Keywords: acute kidney injury; mitochondrial dysfunction; mitochondrial dynamics; mitophagy; biomarkers
(This special issue belongs to the Section Chemical Biology)
Recent Advances in Retroviruses and Endogenous Retroviruses (ERVs) in Mammalian Placenta and Beyond 2025 submission deadline 30 Nov 2025 | 1 articles | Viewed by 1134 | Submission Open
Keywords: retroviruses; ERVs (endogenous retroviruses); placental diversity; organ development (stem cells); immunoregulation
(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)
Molecular and Cellular Mechanisms of Megakaryocyte and Platelet Production
edited by Pedro J. Real and
submission deadline 30 Nov 2025 | Viewed by 485 | Submission Open
Keywords: megakaryocytes; platelets; omics; platelet disorders; inflammation
(This special issue belongs to the Section Cellular Biochemistry)
Thyroid Cancer: Molecular Mechanisms and Targeted Therapies submission deadline 30 Nov 2025 | Viewed by 406 | Submission Open
Keywords: differentiated thyroid cancer; medullary thyroid cancer; anaplastic thyroid carcinoma; advanced/metastatic thyroid cancer; refractory thyroid cancer; molecular biomarkers; oncogenic signaling pathways; thyroid cytology; targeted therapy; tyrosine kinase inhibitors; immune checkpoint inhibitors; therapeutic strategies; thyroid cancer prognosis; epigenomics in thyroid cancer
(This special issue belongs to the Section Molecular Medicine)
New Insight into the Structures and Host Cell Interactions of Emerging Viruses
edited by and
submission deadline 30 Nov 2025 | Viewed by 271 | Submission Open
Keywords: emerging viruses; virus structure; structural biology; Cryo-EM/Cryo-ET/CLEM; virus– host interactions; viral receptor binding and entry; viral assembly; maturation; and egress; immune evasion; molecular dynamics simulation; antiviral targets
(This special issue belongs to the Section Molecular Biophysics: Structure, Dynamics, and Function)
Cancer Biology: Machine Learning and Bioinformatics
edited by Annalisa Santucci, and
submission deadline 30 Nov 2025 | Viewed by 237 | Submission Open
Keywords: cancer biology; bioinformatics; machine learning; big data
(This special issue belongs to the Section Bioinformatics and Systems Biology)
New Technologies and Translational Approach for an Early Diagnosis of Bipolar Spectrum and Hyperactive and Novelty Seeking Profiles
edited by , Serdar Dursun and
submission deadline 30 Nov 2025 | Viewed by 232 | Submission Open
Keywords: psychiatry; mental health; bipolar disorders; mood; biomarkers; new technology; BD
Advances in Molecular Mechanisms in Chronic Kidney Disease
edited by and María J. Izquierdo
submission deadline 30 Nov 2025 | Viewed by 232 | Submission Open
Keywords: chronic kidney disease; end-stage kidney disease; etiological diagnosis; biomarkers; personalized medicine; humans
(This special issue belongs to the Section Molecular Biomarkers)
Deciphering Biomolecular Multimeric Systems: Computational Advances in Structure, Dynamics, and Function
edited by , Jinping Lei and Hui Wang
submission deadline 30 Nov 2025 | Viewed by 226 | Submission Open
Keywords: molecular glue; molecular simulations; PROTAC; binding affinity; binding mode; MSM; membrane
Novel Evidence About Hydrogen Sulfide (H2S)-Donor Molecules as Innovative Therapeutical Tools 2025
edited by
submission deadline 30 Nov 2025 | Viewed by 215 | Submission Open
Keywords: hydrogen sulfide (H2S)-donor; H2S-releasing molecule; H2S-hybrid drug; hydrogen sulfide; therapeutical tool
(This special issue belongs to the Section Chemical Biology)
Genetic Insights into Biological Mechanisms Governing Aging
edited by and Duilio Michele Potenza
submission deadline 30 Nov 2025 | Viewed by 208 | Submission Open
Keywords: aging; genetics; cellular senescence; oxidative stress; inflammation; mitochondrial function
(This special issue belongs to the Section Molecular Genetics)
Mitochondrial Dysfunction: Mechanisms and Advances submission deadline 30 Nov 2025 | Viewed by 197 | Submission Open
Keywords: mitochondrial disease; neurological disorders; cancer; targeted therapy
Molecular Mechanisms of Olfactory and Gustatory System
edited by
submission deadline 30 Nov 2025 | Viewed by 187 | Submission Open
Keywords: olfaction; smell; taste; chemical stimuli; sensation; perception; Volabolome; advanced diagnostic techniques
(This special issue belongs to the Section Molecular Biology)
Advances in Type 2 Diabetes: Molecular Mechanisms and Therapeutic Innovations
edited by Orien L. Tulp
submission deadline 30 Nov 2025 | Viewed by 170 | Submission Open
Keywords: type 2 diabetes (T2DM); insulin resistance; GLUT4; sirtuins; epigenetic expression; nutrition; pharmacotherapeutics
(This special issue belongs to the Section Molecular Medicine)
Multiple Sclerosis Pathogenesis: Bridging Innate and Adaptive Immunity
edited by Jo Anne Stratton and Stephanie Zandee
submission deadline 30 Nov 2025 | Viewed by 156 | Submission Open
Keywords: multiple sclerosis; innate– adaptive immune crosstalk; glial biology and complement; cellular immunology; biomarkers
(This special issue belongs to the Section Molecular Medicine)
Back to TopTop