Molecular Mechanism and Regulation of Adipogenesis, Adipose Tissue Inflammation and Metabolism
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Biological Factors".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 1448
Special Issue Editor
Interests: immunometabolism; obesity; adipogenesis; adipose tissue inflammation; adipose immune microenvironment
Special Issue Information
Dear Colleagues,
The obesity epidemic has spread across the world and poses a health risk to the entire globe. Obesity leads to the development of several metabolic abnormalities, including cardiovascular disease, type 2 diabetes mellitus (T2DM), and various immune-mediated disorders. Obesity is also associated with increased immune cell infiltration in the adipose tissue (AT). AT infiltrates macrophages, neutrophils, natural killer cells (NK), and T cells that exhibit distinct phenotypes in healthy and obese conditions. AT-resident macrophages synergistically coordinate with adipocytes to orchestrate the body’s energy metabolism. The immune functions during AT inflammation and whether there is cross-talk between adipocytes and immune cells during obesity remains unclear. Thus, resetting the key signaling in AT during obesity and adipogenesis will provide an innovative approach to the management and therapeutics of obesity.
This Special Issue aims to highlight recent advances made in the immunometabolism field that are useful in preventing the individual risk of developing metabolic disease and providing invaluable help for advancing therapeutic strategies to combat obesity and metabolic disease.
We encourage people interested in these topics to present original research articles, the molecular mechanism underlying the regulation of adipogenesis, immunometabolism, and specific targets in the progression and development of obesity. A few critical and systematic review articles in this area of research that provide a few unique concluding remarks will be considered for inclusion in this Special Issue.
Prof. Dr. Udai P Singh
Guest Editor
Manuscript Submission Information
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Keywords
- immunometabolism
- obesity
- adipogenesis
- adipose tissue inflammation
- adipose immune microenvironment
- immune-adipose tissue cross-talk
- hormones
- high-fat diet
- metabolic disease
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