Zebrafish: A Gateway to Understanding Human Disease
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: 28 February 2026 | Viewed by 5
Special Issue Editors
2. Children's Health Research Institute, London, ON, Canada
Interests: cell and developmental biology; cell signalling; zebrafish embryogenesis; mouse development; Wnt and hedgehog signalling
Interests: brain development and regeneration; development of dopamine and GABA neurons; control of gene expression; transgenic models; evolution of developmental mechanisms; zebrafish models of disease including Parkinson's disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are pleased to host this Special Issue highlighting the importance of Zebrafish and its contributions to science. We are reminded of the excellent study conducted by Bedell et al., 2025 (Commun Biol 8, 739 (2025). https://doi.org/10.1038/s42003-025-07496-z) and other studies highlighting the accolades of this model. This Special Issue aims to provide a collection of papers centered on the utility that Zebrafish has had in developmental biology, specifically regarding human disease. Most human diseases are not fully understood, and their cellular and molecular mechanisms can be addressed using the Zebrafish. Thus, all original research articles and reviews are welcome. Topics may include but are not limited to Zebrafish genes involved in normal development and their use in deciphering the role(s) related to a human malady. Safe and personalized medical procedures are needed to treat patients suffering from these diseases, and given reverse genetics and CRISPR gene editing, the number of publications in this area has skyrocketed. Towards this end, this Special Issue will focus on recent advances in the field. We will also consider highly innovative articles and short communications on how personalized medicine has benefitted from Zebrafish studies.
Please feel free to contact any of the guest editors or the Editorial Office should you have any questions. We look forward to receiving your contributions.
Prof. Dr. Gregory Kelly
Prof. Dr. Marc Ekker
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- zebrafish development
- genetic pathways in zebrafish and humans
- a better understanding of human disease conditions related to zebrafish
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