Heterocyclic Compounds: Synthesis, Characterization, and Validation
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Chemical Biology".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 20
Special Issue Editor
Interests: medicinal chemistry; organic synthesis; heterocycles; anticancer activity; antimicrobial activity; SAR
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue highlights interdisciplinary research on heterocyclic compounds, which play a key role in organic chemistry, medicinal chemistry, molecular biology, and medical sciences. This Special Issue aims to present the latest advances in the following areas: Innovative synthetic methods, encompassing both classical approaches and strategies utilizing catalysis, flow chemistry, electrochemical methods, photochemical methods, and microwave- or ultrasound-assisted synthesis. Structural and spectroscopic characterization, employing techniques such as NMR, MS, IR, UV-Vis, X-ray structural analysis, and computational methods (DFT and molecular docking), supporting the analysis of physicochemical properties. Biological and medical applications, including the design and evaluation of potential anticancer, antibacterial, antiviral, anti-inflammatory, and neuroprotective drugs, as well as compounds used in imaging diagnostics (e.g., radiopharmaceuticals). Biological and pharmacological validation, including in vitro and in vivo studies, assessment of toxicity, bioavailability, selectivity of action, molecular mechanisms, and translational potential for preclinical and clinical studies. This Special Issue also welcomes review articles that synthesize the current state of knowledge and suggest directions for further research in this dynamically developing field.
Dr. Monika Pitucha
Guest Editor
Manuscript Submission Information
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Keywords
- heterocyclic compounds
- synthesis
- spectroscopy
- molecular modeling
- biological activity
- radiopharmaceuticals
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