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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pharmacokinetics and Pharmacodynamics of Antibacterial and Antivirulence Drugs, 2nd Edition

edited by

Takahisa Yano

submission deadline 30 Nov 2025 | 4 articles | Viewed by 4021 | Submission Open

Keywords: pharmacokinetics; pharmacodynamics; clinical trials; antimicrobial resistance; antibacterials; antivirulence drugs; pathoblockers; antimicrobial use; drug utilization studies; PK/PD modeling; PBPK-modeling

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)

Antimicrobial Susceptibility of Veterinary Origin Bacteria

edited by Luchao Lv and Jing Wang

submission deadline 30 Nov 2025 | 3 articles | Viewed by 3816 | Submission Open

Keywords: antimicrobial resistance; animal-derived resistant; antimicrobial-resistant bacteria; foodborne pathogens

(This special issue belongs to the Section Antibiotics in Animal Health)

Spread of Multidrug-Resistant Microorganisms, 2nd Edition

edited by

Mara Di Giulio

and

Silvia Di Lodovico

submission deadline 30 Nov 2025 | 1 articles | Viewed by 3689 | Submission Open

Keywords: multidrug-resistant organisms; MDR; antibiotic resistance gene; nosocomial infections; new marker of resistance

Innovations in Plant-Based Antibiotic and Antiviral Agents

edited by

Margherita-Gabriella De Biasi

and

Irene Dini

submission deadline 30 Nov 2025 | 2 articles | Viewed by 3485 | Submission Open

Keywords: secondary metabolites; phytochemicals; botanicals; analytical methods; toxicity

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antimicrobial Prescribing, Population Use and Resistance, Impact in Global Health, 3rd Edition

edited by

Juan Manuel Vázquez-Lago

Ana Estany-Gestal

and

Angel Salgado-Barreira

submission deadline 30 Nov 2025 | 1 articles | Viewed by 3350 | Submission Open

Keywords: epidemiology; social behavior; antibiotic resistance; social factors; attitudes; knowledge; practice; qualitative research; public health interventions; antibiotic prescription; community care

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

A Themed Issue in Honor of Dr. Lynne V. McFarland—Clostridioides difficile Infection and Impact of Antibiotics on the Intestinal Microbiome

edited by Ellie J. C. Goldstein and Shan Goh

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2119 | Submission Open

Keywords: Clostridioides difficile infections; intestinal microbiome; infection control practices; antibiotic complications; probiotics; live biotherapeutic products; treatment; prevention

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic Stewardship and Infection Control Strategies in Critical Care

edited by

Susana M. Fernandes

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1921 | Submission Open

Keywords: infection prevention; critical care; sepsis; stewardship practices

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

The Discovery of Novel Antimicrobial Agents to Combat Infections

edited by

Yuanpu Peter Di

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1282 | Submission Open

Keywords: antimicrobials; resistance; bacteriophage; virulence; structure; PD/PK; bacteria; virus; fungus

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Agents for Drug-Resistant Infections: From Identification to Preclinical and Clinical Trials

edited by

Javier Eduardo García Castañeda

and

Zuly Jenny Rivera-Monroy

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1048 | Submission Open

Keywords: antimicrobials agents; drug resistant; anti-cancerogenic agents; drug development; preclinical trials; clinical trials; pharmaceutical optimization

(This special issue belongs to the Section Novel Antimicrobial Agents)

Plant-Based Strategies for the Removal and Degradation of Antibiotics from the Environment

edited by

Giancarlo Angeles Flores

and

Paola Angelini

submission deadline 30 Nov 2025 | 1 articles | Viewed by 612 | Submission Open

Keywords: antibiotics; ARGs; phytoremediation; rhizosphere; plant– microbe interactions; biodegradation; detoxification; environmental pollution; resistance mitigation; sustainable remediation

Resistance and Evolving Biology in Mycobacteria: Multidisciplinarity as a Contemporary Approach

edited by

Irena Arandjelovic

and Dragana Vukovic

submission deadline 30 Nov 2025 | Viewed by 354 | Submission Open

Keywords: tuberculosis; drug resistance; evolutionary biology; pathogen-host interactions

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Novel Approaches to Prevent and Combat Antimicrobial Resistance

edited by

Xiaotao Jiang

submission deadline 30 Nov 2025 | Viewed by 349 | Submission Open

Keywords: antimicrobial peptides; novel antibiotics screening; phage therapy; fecal microbiota transplantation (FMT); dietary and functional food interventions; AMR prevention strategies

Drug Discovery in the Fight Against Bacterial Infections

edited by

Sara M. Soto

and

Raquel G. Soengas

submission deadline 30 Nov 2025 | Viewed by 315 | Submission Open

Keywords: drug discovery against gram-positive bacteria; drug discovery against gram-negative bacteria; drug discovery against fungi; drug discovery against biofilms

Neonatal Infection: Antibiotics for Prevention and Treatment

edited by Cinzia Auriti and Maria Paola Ronchetti

submission deadline 30 Nov 2025 | Viewed by 227 | Submission Open

Keywords: neonatal infections; neonatal sepsis; sepsis definition; antibiotics in newborns; antibiotic stewardship; sepsis biomarkers; sepsis diagnosis in newborns; epidemiology of neonatal infections; fungal invasive infections

Animal-Origin Bacteria: Diversity, Pathogenicity and Antimicrobial Resistance

edited by

Juliana Menezes

Joana Moreira da Silva

and

Adriana Belas

submission deadline 30 Nov 2025 | Viewed by 201 | Submission Open

Keywords: AMR; virulence; bacteria; zoonosis; companion animals; alternative therapy; food-producing animals; exotic animals; wildlife; One Health

Mastitis: Causative Agents, Drug Resistance, and Treatment Approaches—2nd Edition

edited by

Amira A. Moawad

Hosny El-Adawy

and Heinrich Neubauer

submission deadline 30 Nov 2025 | Viewed by 181 | Submission Open

Keywords: mastitis; etiology; multi-drug resistance; alternative bovine mastitis treatment; WGS

(This special issue belongs to the Section Antibiotics in Animal Health)

Antibiotic Resistance and Antimicrobial Stewardship in Veterinary Medicine

edited by Tiana Florea,

Ilie Stelian

and

Degi Janos

submission deadline 30 Nov 2025 | Viewed by 158 | Submission Open

Keywords: antimicrobial stewardship; antibiotics; animals; sustainability; drugs; antimicrobial resistance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Biosynthesis, Antimicrobial Activity, and Therapeutics Development of Novel Peptides

edited by

Jiajun Wang

submission deadline 30 Nov 2025 | Viewed by 151 | Submission Open

Keywords: peptide biosynthesis; novel antimicrobial peptides; antibiotic resistance; improvement of biological stability; optimization of drug delivery systems; immune regulation; AI-driven peptide design; innovation in the field of biomedicine

(This special issue belongs to the Section Antimicrobial Peptides)

Antimicrobial and Anti-Inflammatory Activity of Bioactive Compounds Extracted from Plants, 2nd Edition

edited by

Juliana Garcia

and

Irene Gouvinhas

submission deadline 30 Nov 2025 | Viewed by 147 | Submission Open

Keywords: plants; phytochemicals; bioactive compounds; biological properties; natural products

(This special issue belongs to the Section Plant-Derived Antibiotics)

The Use of Systemic and Topical Antibiotics in Dentistry: Challenges and Future Perspectives

edited by

Sigrun Eick

submission deadline 30 Nov 2025 | Viewed by 145 | Submission Open

Keywords: antibiotics; apical abscess; apical periodontitis; endodontic infection; periapical disease; mouth diseases; topical antibiotics; antimicrobial approaches

Risks and Current Knowledge of Antimicrobial Resistance in Companion Animals

edited by

Djamel Drider

and

Raffaele Scarpellini

submission deadline 30 Nov 2025 | Viewed by 145 | Submission Open

Keywords: antimicrobial resistance; companion animals; dogs; cats; clinically important antibiotics; One Health; reverse zoonosis; zoonosis; AMR epidemiology

(This special issue belongs to the Section Antibiotics in Animal Health)

Small Intestinal Bacterial Overgrowth and Antimicrobials

edited by

Mislav Radić

and

Andrej Belančić

submission deadline 30 Nov 2025 | Viewed by 129 | Submission Open

Keywords: small intestine bacterial overgrowth; antibiotics; probiotics; gut microbiome

(This special issue belongs to the Section Novel Antimicrobial Agents)

The Interventions to Prevent and Reduce Healthcare-Associated Infection

edited by Nasia Safdar

submission deadline 30 Nov 2025 | Viewed by 91 | Submission Open

Keywords: infection; resistance; methicillin-resistant Staphylococcus aureus; vancomycin resistant enterococcus; Clostridioides difficile infection

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Sustainable Innovation in Antibiotic Adjuvants: Developing Strategies to Overcome Antibiotic Resistance and Biofilm Infections

edited by

Anabela Borges

and

Ana C. Afonso

submission deadline 1 Dec 2025 | Viewed by 160 | Submission Open

Keywords: adjuvants; antibiotic resistance; biofilms; drug development; green chemistry; natural products; synergistic interactions

(This special issue belongs to the Section Biosynthesis and Combinatorial Approaches in Antimicrobial Discovery)

Surveillance and Molecular Diagnosis of Antimicrobial-Resistant Pathogens: From Laboratory to Clinical Practice

edited by Neena Kanwar

submission deadline 5 Dec 2025 | Viewed by 113 | Submission Open

Keywords: clinical microbiology; molecular diagnostics; infectious disease epidemiology; antimicrobial susceptibility; microbial culture

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Urinary Tract Infections and Antibiotic Intervention, 2nd Edition

edited by

Majid Mirzazadeh

submission deadline 10 Dec 2025 | Viewed by 359 | Submission Open

Keywords: UTI; antibiotic; microbiome; PCR; next-generation sequencing; urine culture; enhanced quantitative urine cultures; urinary sepsis

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

The Spread of Antibiotic Resistance in Natural Environments

edited by

Daniel Gyamfi Amoako

submission deadline 15 Dec 2025 | 6 articles | Viewed by 18369 | Submission Open

Keywords: antibiotic resistance dissemination; antibiotic pollution; environmental adaptation; mobile genetic elements; ecological impact; environmental microbiome; resistance gene transfer; resistance hotspot; genomic landscape; One Health approach; emerging contaminants; bioinformatics in environmental genomics

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial Resistance and Environmental Health, 2nd Edition

edited by

Akebe Luther King Abia

submission deadline 15 Dec 2025 | 2 articles | Viewed by 3167 | Submission Open

Keywords: public health; environmental health; antibiotic resistance; environmental resistome; antibiotic-resistant bacteria; whole-genome sequencing; metagenomics; climate change and AMR; AMR models and One Health

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic Surveillance and Rational Use in Special Populations: Enhancing Stewardship for Vulnerable Groups

edited by

Phumzile P Skosana

and

Filippo Mariano

submission deadline 20 Dec 2025 | 1 articles | Viewed by 1238 | Submission Open

Keywords: antibiotic stewardship; surveillance systems; special populations; rational use of antibiotics; infectious disease management

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Challenges of Antibiotic Resistance: Biofilms and Anti-Biofilm Agents

edited by

María Melissa Gutiérrez-Pacheco

and

Luis Alberto Ortega-Ramirez

submission deadline 20 Dec 2025 | Viewed by 436 | Submission Open

Keywords: antibiotic resistance; biofilms; quorum sensing; virulence factors; resistance mechanisms; antibiofilm agents; natural compounds; synthetic drugs

(This special issue belongs to the Section Antibiofilm Strategies)

Environmental Risk and Antibiotic Resistance in Hospital-Acquired Infections

edited by

Catherine Neuwirth

submission deadline 20 Dec 2025 | Viewed by 113 | Submission Open

Keywords: nosocomial outbreak; environmental reservoir; investigation; corrective actions; short- and long-term outcomes

Phage Applications from Diagnostics to Treatment of Bacterial Infections in a One Health World

edited by

Mariagrazia Di Luca

and

Goran Vukotic

submission deadline 31 Dec 2025 | 8 articles | Viewed by 39385 | Submission Open

Keywords: phage therapy; antibiotic resistance; bacteriophages; regulatory framework; veterinary medicine; agriculture treatment; aquaculture

(This special issue belongs to the Section Bacteriophages)

Antibiotic Use and Antimicrobial Stewardship for Children in the Emergency Department

edited by

Michael Barrett

and

Spyridon Karageorgos

submission deadline 31 Dec 2025 | 7 articles | Viewed by 39233 | Submission Open

Keywords: pediatric ED; ambulatory; antimicrobial stewardship; antibiotic use; antimicrobial resistance; point-of-care testing

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Bacterial Detection, Identification, and Antimicrobial Susceptibility Testing

edited by

Gabriele Bianco

submission deadline 31 Dec 2025 | 8 articles | Viewed by 27124 | Submission Open

Keywords: identification methods; rapid diagnostics; MALDI-TOF MS; molecular testing; rapid antimicrobial susceptibility testing; antimicrobial susceptibility; synergy testing; β -lactam/β -lactamase inhibitor; fosfomycin; colistin

Epidemiology and Mechanism of Bacterial Resistance to Antibiotics

edited by

Gabriela Loredana Popa

and

Mircea Ioan Popa

submission deadline 31 Dec 2025 | 10 articles | Viewed by 27034 | Submission Open

Keywords: multi-drug resistant (MDR); classic and molecular epidemiology; plasmids; resistance gene

Computational Approaches in Discovery and Design of Antimicrobial Peptides—2nd Edition

edited by

Guillermin Agüero-Chapin

Yovani Marrero-Ponce

and

Agostinho Antunes

submission deadline 31 Dec 2025 | 7 articles | Viewed by 24466 | Submission Open

Keywords: rational search and design of AMPs; alignment-based and alignment-free approaches; machine-learning; artificial intelligence; biodiscovery with associated computational analyses/tools; non-conventional in silico approaches

(This special issue belongs to the Section Antimicrobial Peptides)

Antibiotic Resistance: A One-Health Approach, 2nd Edition

edited by

Piera Anna Martino

submission deadline 31 Dec 2025 | 9 articles | Viewed by 24181 | Submission Open

Keywords: antibiotic-resistance; One Health; virulence factors; genomics; novel natural molecules; antimicrobial stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Preventing Antimicrobial Resistance in Hospitals: Infection Control and Antibiotic Use

edited by Dorota Pastuszak-Lewandoska,

Filip Bielec

and Małgorzata Brauncajs

submission deadline 31 Dec 2025 | 7 articles | Viewed by 15929 | Submission Open

Keywords: clinical antibiotic use; hospital infection control; healthcare-associated infections; resistance mitigation strategies; alternative therapies; antibiotic stewardship; molecular mechanisms of AMR; new therapeutic combinations of antibiotics; antimicrobial synergy

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Bacteriophage Therapy a Renaissance Weapon Recent Developments and Application, 2nd Edition

edited by

Aneta Skaradzińska

and

Paulina Śliwka

submission deadline 31 Dec 2025 | 9 articles | Viewed by 15633 | Submission Open

Keywords: bacteriophages; phage therapy; application of phages; antibiotic-resistance; antibacterial therapies

(This special issue belongs to the Section Bacteriophages)

Antibiotic Treatment on Surgical Infections

edited by

Fausto Catena

submission deadline 31 Dec 2025 | 3 articles | Viewed by 14125 | Submission Open

Keywords: surgical site; infection; emergency surgery; prevention

Antimicrobial Resistance in the Community Setting: The Other Side of the Coin

edited by

Luigi Principe

submission deadline 31 Dec 2025 | 4 articles | Viewed by 13215 | Submission Open

Keywords: emerging resistance; multidrug resistance; emerging virulence; community setting; Staphylococcus aureus; Enterococcus spp.; Streptococcus spp.; Haemophilus spp.; Moraxella spp.; Mycobacterium spp.; Neisseria spp.; Salmonella spp.; Shigella spp.; Campylobacter spp.; anaerobes; fungi

Antimicrobial Activity of Plants Against Emerging or Drug-Resistant Human Pathogens

edited by

Andrés H. Uc-Cachón

and

Gloria María Molina-Salinas

submission deadline 31 Dec 2025 | 7 articles | Viewed by 13064 | Submission Open

Keywords: anti-infective agents; antimicrobial activity; human pathogens; medicinal plants; natural products; phytodrugs

(This special issue belongs to the Section Plant-Derived Antibiotics)

Inappropriate Use of Antibiotics in Pediatrics

edited by Brian R. Lee

submission deadline 31 Dec 2025 | 4 articles | Viewed by 12487 | Submission Open

Keywords: antimicrobial stewardship; inappropriate antibiotic prescription; antimicrobial resistance; pediatrics

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Natural Peptides to Combat Conventional Antibiotic Resistance

edited by

Christopher Shaw

Tianbao Chen

and

Lei Wang

submission deadline 31 Dec 2025 | 3 articles | Viewed by 11581 | Submission Open

Keywords: antimicrobial peptide; peptide modification; antibiotic resistance; structure– activity relationship; membrane selectivity; resistant strains

(This special issue belongs to the Section Antimicrobial Peptides)

Advancing the Discovery and Development of New Antibiotics through Drug Repurposing

edited by Songping Huang

submission deadline 31 Dec 2025 | 4 articles | Viewed by 10579 | Submission Open

(This special issue belongs to the Section Novel Antimicrobial Agents)

Multitalented Synthetic Antimicrobial Compounds: From Design to Effect

edited by

Tsz Tin Yu

and

Maria Fernanda N. N. Carvalho

submission deadline 31 Dec 2025 | 4 articles | Viewed by 9006 | Submission Open

Keywords: antimicrobial resistance; antibiotic development; the design of antimicrobial compounds; the synthesis of antimicrobial compounds; medicinal chemistry; bioorganic chemistry; antimicrobial properties; the mechanisms of antimicrobial activity; bioinorganic

(This special issue belongs to the Section Novel Antimicrobial Agents)

A One Health Approach to Antimicrobial Resistance, 2nd Edition

edited by

Beatriz Robredo

submission deadline 31 Dec 2025 | 6 articles | Viewed by 7604 | Submission Open

Keywords: One Health; antibiotic; antimicrobial resistance; animal; food; environment

Antimicrobial Resistance in Veterinary Science, 2nd Edition

edited by

Nahla O. Eltai

submission deadline 31 Dec 2025 | 4 articles | Viewed by 6555 | Submission Open

Keywords: AMR; veterinary animals; farm animals; food animals; wild animals; resistance

(This special issue belongs to the Section Antibiotics in Animal Health)

Molecular Characterization and Antimicrobial Resistance of Pathogens Isolated from Animals

edited by

Isabel Carvalho

submission deadline 31 Dec 2025 | 3 articles | Viewed by 6231 | Submission Open

Keywords: antibiotic resistance; molecular biology; microbiology; genomics; multi-drug resistance; One Health; animals

(This special issue belongs to the Section Antibiotics in Animal Health)

Therapy of Infectious Diseases Among Children and Adults: The Role of Antibiotics in Daily Practice

edited by

Magdalena Baymakova

and

Valeri R. Velev

submission deadline 31 Dec 2025 | 4 articles | Viewed by 5434 | Submission Open

Keywords: аntibiotic use among children; аntibiotic use among adults; аntibiotic use among outpatients; аntibiotic use among inpatients; antibiotic resistance; improper antibiotic use; antibiotic quality control

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Displaying special issue 51-100 on page 2 of 7.

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