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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Advances in Antibiotic Therapy in the Gastroenterology Field

edited by

Giuseppe Guido Maria Scarlata

and Francesca Serapide

submission deadline 30 Sep 2026 | 4 articles | Viewed by 5740 | Submission Open

Keywords: antibiotic therapy; antimicrobial resistance; gastroenterology; infectious diseases; microbiology; gut–liver axis; antimicrobial stewardship; infection control; biomarkers; diagnosis; epidemiology

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Current Advances and Innovations in Anti-Infective Agents Discovery

edited by

Valnês da Silva Rodrigues-Junior

submission deadline 30 Sep 2026 | 4 articles | Viewed by 5219 | Submission Open

Keywords: drug development; antiviral; antibacterial; antifungal; antiparasitic

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotics for Primary Care Practice

edited by Reza Nassiri

submission deadline 30 Sep 2026 | 2 articles | Viewed by 5119 | Submission Open

Keywords: primary care practice; nursing home practice; remote practice; antibiotic prescription habits; antibiotic resistance in clinical practice; public health consequences of antibiotic resistance; antibiotics stewardship practices; elements of safe practice

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Resistance and One Health: Environmental Health, Food Safety, and Practice of Health Professionals

edited by

Teresa Letra Mateus

and

Francisco Cortez Nunes

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4021 | Submission Open

Keywords: antibiotics; antibiotic resistance; guidelines compliance; health communication; One Health; public awareness

Pioneering the Microbiome—Infections, Inflammation, Inflammatory Bowel Disease and the Role of Antibiotic Therapy

edited by

Gaurav Agrawal

and

Roger Pickup

submission deadline 30 Sep 2026 | 1 articles | Viewed by 3688 | Submission Open

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial Resistance and Epidemiological Study of Clinically Relevant Pathogens, 2nd Edition

edited by

Florin George Horhat

Adrian Man

and

Delia Muntean

submission deadline 30 Sep 2026 | 4 articles | Viewed by 2909 | Submission Open

Keywords: antibacterial activity; antimicrobial resistance; infections; multidrug-resistant pathogens; virulence gene expression; drug discovery; epidemiological study

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

A Themed Issue in Honor of Professor Stefan Schwarz—Antimicrobial Resistance of Bacteria of Animal Origin: Diagnostics, Monitoring, Mechanisms and Epidemiology

edited by

Igor Loncaric

and Séamus Fanning

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2855 | Submission Open

Keywords: antimicrobial resistance; animals; resistance genes; mechanism of resistance; MRSA; ESBL; staphylococci; enterobacterales

Periprosthetic Joint Infections: Antimicrobial Biomaterials and Antibiotic Treatment

edited by

Konstantinos Anagnostakos

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2362 | Submission Open

Keywords: periprosthetic joint infection (PJI); local antibiotic therapy; systemic antibiotic therapy; bone cement; antibiotic carrier; one-stage treatment; two-stage treatment

Resistance, Treatment and Prevention of ESKAPE Pathogens

edited by

Steven E. Fiester

and

William Penwell

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2332 | Submission Open

Keywords: antibiotic resistance; prevention methods; treatment strategies; ESKAPE pathogens

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Molecular Characteristics and Genomic Epidemiology of Multidrug-Resistant Gram-Negative Bacteria

edited by

Piotr Majewski

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1669 | Submission Open

Keywords: multidrug-resistant gram-negative bacteria; antimicrobial resistance; whole-genome sequencing; molecular epidemiology; resistance mechanisms; horizontal gene transfer; infection control; antimicrobial stewardship

Genetic Blueprints of Resistance, Persistence and Tolerance: Biochemical and Omic Perspectives on Antibiotic Activity

edited by

Viviana Cafiso

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1657 | Submission Open

Keywords: AMR; persistence; tolerance genetic plasticity; genomics; transcriptomics proteomics; biochemical mechanisms; biomarkers

(This special issue belongs to the Section Genetic and Biochemical Studies of Antibiotic Activity and Resistance)

Feature Reviews in Mechanism and Evolution of Antibiotic Resistance 2026

edited by

Krisztina M. Papp-Wallace

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1655 | Submission Open

Keywords: antibiotic resistance mechanisms; intrinsic and acquired resistance; antimicrobial selective pressure; bacterial evolutionary dynamics; omics and molecular epidemiology

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Limits and Risks of Quorum Quenching in Medicine

edited by

Emil Paluch

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1581 | Submission Open

Keywords: quorum quenching; quorum sensing; biofilm; Pseudomonas aeruginosa; Staphylococcus aureus; antimicrobial resistance; anti-virulence therapy

(This special issue belongs to the Section Novel Antimicrobial Agents)

Novel Antimicrobials for ESKAPE Pathogens: From Research to Treatment

edited by

Nalin Abeydeera

, Bishnu Pant and

Sara Scutera

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1409 | Submission Open

Keywords: antimicrobial resistance; ESKAPE pathogens; novel antibiotics; metal-based antimicrobials; antibiofilm agents; drug discovery; nanomaterials; host-directed therapy; combination therapy

(This special issue belongs to the Section Novel Antimicrobial Agents)

Bacteriocins and Antimicrobial Peptides in the Era of Antimicrobial Resistance

edited by

Umme Laila Urmi

and

Shyam Kumar Mishra

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1273 | Submission Open

Keywords: bacteriocins; antimicrobial peptides; antimicrobial resistance; multidrug-resistant pathogens; novel therapeutics

Antimicrobial Resistance in Neonatal Infections: Challenges and Strategies

edited by

Vasilios Giapros

, Maria Baltogianni and Niki Dermitzaki

submission deadline 30 Sep 2026 | 1 articles | Viewed by 946 | Submission Open

Keywords: antibiotic resistance; neonatal intensive care unit; neonatal sepsis; antibiotic stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Resistance Detection and Surveillance

edited by Célia Nogueira

submission deadline 30 Sep 2026 | 1 articles | Viewed by 759 | Submission Open

Keywords: antimicrobial resistance; resistance gene detection; surveillance systems; molecular diagnostics; One Health; bioinformatics

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Insights into Bacterial Resistance to Beta-Lactam Antibiotics and Treatment Approaches

edited by

Maria Chatzidimitriou

and

Efthymia Protonotariou

submission deadline 30 Sep 2026 | Viewed by 481 | Submission Open

Keywords: antibiotic resistance; carbapenemase; Klebsiella pneumoniae; high-risk clones

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Molecular and Therapeutic Insights into Antimicrobial Candidates and Antibiotics

edited by

Fabio Aguiar Alves

and

Bruno de Araujo Penna

submission deadline 30 Sep 2026 | Viewed by 458 | Submission Open

Keywords: antimicrobial resistance; novel antimicrobial agents; molecular mechanisms; therapeutic applications

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Aquatic AMR Hotspots: Antibiotic Contamination, Resistance Gene Flow, and Environmental Reservoirs

edited by

Ertugrul Terzi

submission deadline 30 Sep 2026 | Viewed by 333 | Submission Open

Keywords: aquatic environment; multidrug-resistant bacteria; plasmids; horizontal gene transfer; mobile genetic elements; antimicrobial resistance genes; MAR index

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Therapeutic Drug Monitoring for Antimicrobial Agents

edited by

Dario Cattaneo

and

Giammarco Baiardi

submission deadline 30 Sep 2026 | Viewed by 289 | Submission Open

Keywords: therapeutic drug monitoring; antibiotics; antifungal agents; pharmacokinetics; pharmacodynamics; drug-drug interactions; bioanalytical techiques

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Innovative Drug Development for Combating Antibiotic Resistance

edited by

Zeinab Khalil

submission deadline 30 Sep 2026 | Viewed by 236 | Submission Open

Keywords: antibiotic resistance; antimicrobial drug discovery; β-lactamases; efflux pumps; biofilms and persistence; adjuvant/combination therapy; anti-virulence strategies; bacteriophage therapy; AI-enabled antibiotic design

(This special issue belongs to the Section Novel Antimicrobial Agents)

Hydrogel Coatings and Bioactive Molecules for Wound Healing and Cosmetic Applications

edited by

Skander Hathroubi

submission deadline 30 Sep 2026 | Viewed by 223 | Submission Open

Keywords: hydrogel-based coatings; hydroge-coated materials; antioxidant ant-inlammatory; antimicrobial peptides; bloactive molecules

(This special issue belongs to the Section Antimicrobial Materials and Surfaces)

Antibiotic Resistance and Antimicrobial Use in Pediatric Wards

edited by

Evanthia Botsa

and

Spyridon Karageorgos

submission deadline 1 Oct 2026 | Viewed by 418 | Submission Open

Keywords: antimicrobial resistance (AMR); pediatric infectious diseases; hospital-acquired infections; antimicrobial stewardship; multidrug-resistant organisms (MDROs); diagnostic innovations in pediatrics

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Advances in the Field of Biofilm-Associated Musculoskeletal Infections

edited by

Kordo Saeed

submission deadline 10 Oct 2026 | 5 articles | Viewed by 22520 | Submission Open

Keywords: musculoskeletal infections; biofilm-associated; mycobacterial-associated; implant-related infections

(This special issue belongs to the Section Antibiofilm Strategies)

Antibiotic Prophylaxis and Stewardship in Surgical Infection

edited by

Arda Isik

submission deadline 10 Oct 2026 | 1 articles | Viewed by 1564 | Submission Open

Keywords: surgical site infection; antibiotic prophylaxis; antimicrobial stewardship; postoperative infection; perioperative care; infection control; antibiotic resistance; surgical outcomes

Antibiotic Resistance: The Role of Aquatic Environments

edited by

Jason W. Marion

and Matthew D. Stocker

submission deadline 15 Oct 2026 | 3 articles | Viewed by 7516 | Submission Open

Keywords: antibiotic resistance; water; wastewater; One Health; antibiotic misuse; antimicrobial resistance genes; microbiology; fecal indicator bacteria; mobile genetic elements; resistome; pollution; environment; water bodies; water treatment; waterborne disease; public health; risk assessment; sanitation; hygiene; aquatic environments

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic Resistance in Hospital-Acquired Infections, 2nd Edition

edited by Andreea-Loredana Golli and

Ovidiu Zlatian

submission deadline 15 Oct 2026 | 1 articles | Viewed by 1158 | Submission Open

Keywords: healthcare-associated infections; multi-drug resistance; epidemiology; antimicrobial therapy; patient outcomes; infection prevention and control strategies

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic Resistance: A One-Health Approach, 3rd Edition

edited by

Piera Anna Martino

submission deadline 20 Oct 2026 | Viewed by 313 | Submission Open

Keywords: antibiotic-resistance; One Health; virulence factors; genomics; novel natural molecules; antimicrobial stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Phage-Based Biotechnologies for Targeted Bacterial Control: From Phage Biology to Sustainable Applications

edited by

Jaime Romero

submission deadline 30 Oct 2026 | 1 articles | Viewed by 1844 | Submission Open

Keywords: bacteriophages; targeted bacterial control; phage-based biotechnologies; phage–host interactions; endolysins and phage-derived enzymes; antimicrobial alternatives; microbial ecology; sustainable biocontrol; phage engineering

(This special issue belongs to the Section Bacteriophages)

Antibiotic Stewardship Implementation Strategies

edited by

Massimo Sartelli

submission deadline 31 Oct 2026 | 7 articles | Viewed by 13539 | Submission Open

Keywords: antibiotic stewardship; implementation; hospital settings

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Bioactive Natural Products in Antimicrobial Resistance Management

edited by

Ljubiša Šarić

Zorica Tomičić

and

Ružica Tomičić

submission deadline 31 Oct 2026 | 4 articles | Viewed by 13136 | Submission Open

Keywords: antimicrobials; antimicrobial resistance; bioactive natural products; novel antimicrobial agents; phytochemicals

(This special issue belongs to the Section Plant-Derived Antibiotics)

Mechanisms of Microbial Biofilm Resistance and New Methods for Biofilm Control

edited by

Gianmarco Mangiaterra

submission deadline 31 Oct 2026 | 4 articles | Viewed by 11205 | Submission Open

Keywords: quorum sensing; chronic infections; antibiotic resistance; persistence; efflux pumps

(This special issue belongs to the Section Antibiofilm Strategies)

Antibiotic Therapy in Respiratory Tract Infections (RTIs)

edited by Ágnes Tóth and

Attila Csaba Nagy

submission deadline 31 Oct 2026 | 4 articles | Viewed by 10558 | Submission Open

Keywords: antibiotic therapy; respiratory tract infections; clinical guidelines; prescribing practices; antibacterial resistance; antimicrobial stewardship

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Periodontal Bacteria and Periodontitis: Infections and Therapy

edited by Anna Skurska

submission deadline 31 Oct 2026 | 3 articles | Viewed by 8113 | Submission Open

Keywords: periodontitis; infection; antibiotics; antibacterial activities

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Epidemiology and Treatment of Microbial Infections in Respiratory Diseases

edited by

Marija Vukoja

and

Peđa Kovačević

submission deadline 31 Oct 2026 | 3 articles | Viewed by 7623 | Submission Open

Keywords: pulmonary infections; respiratory diseases; epidemiology; treatment

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Evidence in Antibiotic Mastitis Therapy

edited by

Volker Krömker

and

Paolo Moroni

submission deadline 31 Oct 2026 | 4 articles | Viewed by 6648 | Submission Open

Keywords: antibiotic mastitis treatment; targeted; selective; pathogens; mastitis history; new infections

(This special issue belongs to the Section Antibiotics in Animal Health)

Genetic Mechanisms of Bacterial Survival: Antibiotic Resistance and Defense Strategies

edited by

Caio Augusto Martins Aires

and

Thiago Pavoni Gomes Chagas

submission deadline 31 Oct 2026 | 2 articles | Viewed by 5036 | Submission Open

Keywords: antimicrobial resistance mechanisms; disinfectant and antiseptic resistance; biofilm formation; genomic insights; horizontal gene transfer

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

New Inhibitors for Overcoming Antimicrobial Resistance

edited by

Humberto Medeiros Barreto

and

Sofia Santos Costa

submission deadline 31 Oct 2026 | 3 articles | Viewed by 4704 | Submission Open

Keywords: antimicrobial resistance; resistance mechanisms; inhibitors; enzymatic inhibitors; efflux; biofilms

Antibiotic Synthesis, 2nd Edition

edited by

Naresh Kumar

and

Tsz Tin Yu

submission deadline 31 Oct 2026 | 3 articles | Viewed by 4621 | Submission Open

Keywords: new antimicrobial compounds; dual-action antimicrobials; new antimicrobial targets; targeted delivery of antibiotics; new scaffolds for antimicrobial discovery; discovery of new antimicrobial mechanisms

(This special issue belongs to the Section Novel Antimicrobial Agents)

Global Partnerships in Response to Antimicrobial Resistance: From Policy to Practice

edited by

Helena Rosado

submission deadline 31 Oct 2026 | 4 articles | Viewed by 3321 | Submission Open

Keywords: antimicrobial resistance; antimicrobial stewardship; global health partnerships; collaboration; low- and middle-income countries; health systems strengthening; actionable implementation; AMR interventions

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotic Susceptibility Testing and Rapid Diagnostics of Antimicrobial Resistance

edited by Maria Grazia Bocci and Giulia Capecchi

submission deadline 31 Oct 2026 | 5 articles | Viewed by 3131 | Submission Open

Keywords: antimicrobial resistance; antibiotic susceptibility testing; rapid diagnostics; molecular detection; point-of-care testing; clinical microbiology

Genomic Characterization of Multidrug-Resistant Bacteria Isolated from Animals and Animal-Derived Foods

edited by

Gabriel Augusto Marques Rossi

and

Fábio P. Sellera

submission deadline 31 Oct 2026 | 3 articles | Viewed by 1907 | Submission Open

Keywords: antimicrobial resistance genes; whole-genome sequencing; one health; foodborne pathogens; mobile genetic elements

(This special issue belongs to the Section Antibiotics in Animal Health)

Metal-Based Antibiotics and Therapeutics

edited by

Sotiris K Hadjikakou

and

Christina N. Banti

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1848 | Submission Open

Keywords: biological inorganic chemistry; metallotherapeutics; metal-based antibiotics; antimicrobial compounds; antimicrobial resistance (AMR); antimicrobials materials or nanoparticles; active medical devices

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Properties of Natural Substances: Alternatives for Managing Microbial Contamination

edited by

Bojana Danilović

and

Ivana Karabegović

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1687 | Submission Open

Keywords: antimicrobial activity; microbial contamination; essential oils; plant extracts

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antibiotic Prescribing in Primary Dental Care—2nd Edition

edited by

Kristina Peros

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1430 | Submission Open

Keywords: primary dental care; antibiotic prescribing; rational drug prescribing; antibiotic stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Sustainable Biocontrol Strategies Across the Food Production Chain: Bacteriophages, Microbial Antimicrobials, and One Health Solutions to Antimicrobial Resistance

edited by

Wattana Pelyuntha

and

Yosra A. Helmy

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1420 | Submission Open

Keywords: antimicrobial resistance (AMR); biocontrol strategies; bacteriophage; microbial antimicrobials; one health; food production chain

Diagnostics and Antibiotic Therapy in Orthopedic Infections

edited by

Jason Young

and Mengnai Li

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1216 | Submission Open

Keywords: prosthetic joint infection; fracture-related infection; septic arthritis; osteomyelitis diagnostics; antibiotic therapy

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Optimization of Antibiotic Use in Hospitals: From Bench to Bedside

edited by

Anna Benini

Davide Gibellini

and

Annarita Mazzariol

submission deadline 31 Oct 2026 | 1 articles | Viewed by 708 | Submission Open

Keywords: resistant microorganisms; antimicrobial resistance; new antibiotics; deprescribing of antibiotics; PK/PD parameters; diagnostic tests; multidisciplinary team

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Beyond Bacteria: Exploring the Biology and Treatment of Understudied Fungal Biofilms

edited by

Whitni Redman

and

Wolf-Rainer Abraham

submission deadline 31 Oct 2026 | Viewed by 631 | Submission Open

Keywords: fungal biofilms; bacterial biofilms; interkingdom biofilms; host-pathogen interactions; biofilms and methodologies; mixed-species infections; therapeutics; fungal–bacterial interactions

(This special issue belongs to the Section Antibiofilm Strategies)

Displaying special issue 51-100 on page 2 of 7.

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