Optimization of Antibiotic Use in Hospitals: From Bench to Bedside

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotics Use and Antimicrobial Stewardship".

Deadline for manuscript submissions: 31 October 2026 | Viewed by 304

Special Issue Editors


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Guest Editor
Pharmacology Section, Department of Diagnostic and Public Health, University of Verona, Verona, Italy
Interests: antimicrobial drugs; antimicrobial resistance; antimicrobial PK/PD
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Guest Editor
Section of Microbiology, Department of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy
Interests: biology of pathogens (e.g., bacteria, viruses, parasites, fungi); mechanisms of infection; antimicrobials; antimicrobial resistance
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Section of Microbiology, Department of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy
Interests: antibiotic resistance; molecular mechanisms of resistance; bone infection
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Antimicrobial resistance is currently recognized as one of the most important clinical emergencies in hospital wards all around the world. It is particularly present in infectious disease wards, intensive care wards, orthopedics wards, and surgical departments, and it is carefully studied in research laboratories and pharmaceutical industries. This emergency can be fought through supporting research on the discovery of new antibiotics, implementing rapid diagnostic tests to identify resistant microorganisms and their resistance to old and new antibiotics.

On this basis, appropriate antibiotic selection involves selecting the appropriate antibiotics for the resistant microorganisms involved in the infection. The prescription of different antibiotics must be personalized according to the microorganism involved and each patient’s characteristics, as well as based on the ideal dose and time of administration. Moreover, it is necessary to encourage the overall deprescription of antibiotics and to decrease the duration of therapy. It is critical that the pharmacodynamic and pharmacokinetic regulations (concentration- and time-dependent characteristics) surrounding antibiotic use are strictly respected, and that administration involves specialists from various medical disciplines to form a multidisciplinary team. The strict application of these concepts will enable us to contain and reduce the emergence of antimicrobial drug resistance.

This Special Issue invites submissions of original research articles and review papers. The scope of research topics encompasses, but is not limited to, the rational application of antibiotics in clinical infections, the influence of antibiotic consumption on resistance profiles, and the underlying mechanisms governing the development of antibiotic resistance.

Dr. Anna Benini
Prof. Dr. Davide Gibellini
Dr. Annarita Mazzariol
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • resistant microorganisms
  • antimicrobial resistance
  • new antibiotics
  • deprescribing of antibiotics
  • PK/PD parameters
  • diagnostic tests
  • multidisciplinary team

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Published Papers

This special issue is now open for submission.
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