Periodontal Bacteria and Periodontitis: Infections and Therapy

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotic Therapy in Infectious Diseases".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 458

Special Issue Editor


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Guest Editor
Department of Integrated Dentistry, Medical University of Bialystok, 15-276 Bialystok, Poland
Interests: periodontology

Special Issue Information

Dear Colleagues,

Periodontitis is a progressive and destructive inflammatory disease that affects the teeth supporting tissues. Its complex ethiology takes into account the interaction between subgingival microflora, the body's immune response and environmental factors. Bacterial biofilm is considered the main etiological factor causing gingivitis and leading to the destruction of periodontal tissues. Periopathogens in the subgingival area triggers defense mechanisms associated with the production of inflammatory factors and increased amounts of gingival crevicular fluid. As a result of inflammation and increased expression of proinflammatory cytokines, periodontal tissues are destroyed. Due to the infectious nature of the disease, treatment of periodontitis focuses largely on eliminating bacteria from the oral cavity. This Special Issue seeks manuscripts dealing with periodontal disease, espacially those dealing with its infection nature and therapy, antibiofilm strategies and means that can improve the therapeutic effect. Both original research and review articles are welcome.

Dr. Anna Skurska
Guest Editor

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Keywords

  • periodontitis
  • infection
  • antibiotics
  • antibacterial activities

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Published Papers (1 paper)

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Review

13 pages, 590 KiB  
Review
Potential Shifts in the Oral Microbiome Induced by Bariatric Surgery—A Scoping Review
by Zuzanna Ślebioda, Hélène Rangé, Marta Strózik-Wieczorek and Marzena Liliana Wyganowska
Antibiotics 2025, 14(7), 695; https://doi.org/10.3390/antibiotics14070695 - 10 Jul 2025
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Abstract
Background: The oral microbiome differs in obese patients compared to normal-weight subjects. Microbiologic shifts very often appear after surgical interventions such as bariatric surgery (BS) and in immunocompromised patients. However, the oral microbiome composition and load in subjects after bariatric surgery are [...] Read more.
Background: The oral microbiome differs in obese patients compared to normal-weight subjects. Microbiologic shifts very often appear after surgical interventions such as bariatric surgery (BS) and in immunocompromised patients. However, the oral microbiome composition and load in subjects after bariatric surgery are unclear. Aim: The aim of this review is to summarize the current state of the art related to the oral microbiome shift induced by bariatric surgery and to discuss its implications on oral cavity health. Methods: Electronic databases: PubMed/Medline, Web of Science, and Cochrane Library were searched for articles published up to March 30, 2025, describing prospective studies focused on changes in the oral microbiota of patients who underwent bariatric surgery. Results: Eight studies measuring the oral microbiome with different approaches—16S ribosomal RNA (16S rRNA) sequencing, polymerase chain reaction (PCR), culture, and matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI TOF MS)—were included in this review. The following bariatric techniques were used: sleeve gastrectomy, Roux-en-Y gastric bypass, Omega loop gastric bypass, and laparoscopic gastric plication. The follow-up period ranged from 3 to 12 months. The results of microbiologic studies were unequivocal. There was an increment in Streptococcus mutans reported, high levels of Candida species, and increased rates of some periodontitis-associated bacteria (Porphyromonas gingivalis) in the post-bariatric surgery period, though some studies suggested a shift towards non-pathogenic composition of the oral microbiome in prospective observations. Conclusions: The local oral microbial homeostasis becomes strongly impacted by the bariatric surgical treatment itself as well as its consequences in the further post-operative period. Therefore, obese patients undergoing BS require very careful dental observation. Full article
(This article belongs to the Special Issue Periodontal Bacteria and Periodontitis: Infections and Therapy)
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