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10.2
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Journals
Antibiotics
Special Issues
Antimicrobial Resistance Detection and Surveillance
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Antimicrobial Resistance Detection and Surveillance

A Special Issue of Antibiotics (ISSN 2079-6382) belonging to the section "Mechanism and Evolution of Antibiotic Resistance".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 1221

Editor

Dr. Célia Nogueira

E-Mail Website
Guest Editor
Faculty of Medicine, University of Coimbra, 3000-504 Coimbra, Portugal
Interests: antimicrobial resistance; mechanisms of antibiotic resistance; natural resources as a source of new antimicrobials; epidemiology of bacterial infections

Special Issue Information

Dear Colleagues,

Antimicrobial resistance (AMR) represents a critical and escalating threat to global health, undermining the effectiveness of essential antimicrobial therapies and compromising interventions across human, animal, and environmental domains. Robust surveillance systems and innovative detection approaches are therefore indispensable for tracking the emergence, dissemination, and evolution of resistant bacteria and resistance determinants, ultimately informing clinical decision-making, public health interventions, and policy development worldwide.

By prioritizing the harmonization of international surveillance standards and the integration of One Health data across human, animal, and environmental sectors, this Special Issue aims to provide a comprehensive platform for advancing the detection, surveillance, and mechanistic understanding of bacterial antimicrobial resistance.

This Special Issue welcomes original research articles and reviews, highlighting cutting-edge technologies, genomic and bioinformatic approaches, and emerging trends in AMR detection and surveillance, with a particular emphasis on translational frameworks that bridge data generation with actionable insights.

Through interdisciplinary collaboration, this Special Issue seeks to accelerate scientific progress toward effective AMR containment strategies and resilient, forward-looking surveillance systems.

Dr. Célia Nogueira
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial resistance
  • resistance gene detection
  • surveillance systems
  • molecular diagnostics
  • One Health
  • bioinformatics

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Review

28 pages, 1324 KB  
Review
Clinical and Epidemiological Landscape of Antimicrobial Resistance and Virulence in Streptococcus Species
by Telma de Sousa, Catarina Silva, José Eduardo Pereira, Gilberto Igrejas and Patricia Poeta
Antibiotics 2026, 15(8), 751; https://doi.org/10.3390/antibiotics15080751 - 3 Aug 2026
Viewed by 844
Abstract
Species of the genus Streptococcus constitute important pathogens in human and veterinary medicine, being responsible for a wide spectrum of infections ranging from mild illnesses to severe invasive pathologies. Although β-lactams continue to be effective against most species, the global increase in resistance [...] Read more.
Species of the genus Streptococcus constitute important pathogens in human and veterinary medicine, being responsible for a wide spectrum of infections ranging from mild illnesses to severe invasive pathologies. Although β-lactams continue to be effective against most species, the global increase in resistance to macrolides, lincosamides, tetracyclines, and, in some cases, reduced susceptibility to penicillin represents a growing challenge for antimicrobial therapy. This review synthesizes the clinical and epidemiological landscape of antimicrobial resistance in the main Streptococcus species, including Streptococcus pyogenes, Streptococcus agalactiae, Streptococcus pneumoniae, Streptococcus dysgalactiae, and other species of clinical and veterinary relevance, addressing their epidemiological profiles, molecular mechanisms of resistance, and virulence factors. The main genetic determinants involved in resistance are discussed, namely the erm, mef, and tet genes, as well as the impact of alterations in penicillin-binding proteins, horizontal gene transfer, and biofilm formation on the persistence of infections and decreased therapeutic efficacy. Simultaneously, the main virulence factors are analyzed, including polysaccharide capsules, adhesins, toxins, extracellular enzymes, and immune response evasion mechanisms that contribute to the colonization, dissemination, and severity of infections. The importance of epidemiological and genomic surveillance, particularly through whole-genome sequencing, in monitoring the spread of resistant clones and identifying determinants of resistance and virulence is also highlighted. Taken together, the data highlight the need to strengthen programs for the rational use of antimicrobials, to promote integrated surveillance strategies from a One Health perspective, and to deepen knowledge about the interaction between antimicrobial resistance and virulence, in order to improve strategies for the prevention, diagnosis, and treatment of infections caused by Streptococcus spp. Full article
(This article belongs to the Special Issue Antimicrobial Resistance Detection and Surveillance)
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