Innovative Drug Development for Combating Antibiotic Resistance
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Novel Antimicrobial Agents".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 133
Special Issue Editor
Interests: marine natural products; microbial cultivation; metabolomics; biosynthetic gene clusters; multi-drug resistant pathogens; antibiotics; microbial ecology; bioactive metabolites; secondary metabolism
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues，
Antibiotic resistance is accelerating across bacterial pathogens, eroding the effectiveness of frontline therapies and threatening routine medical care. This Special Issue, “Innovative Drug Development for Combating Antibiotic Resistance”, focuses on actionable, innovative therapeutic and translational solutions for drug development.
Priority areas include next-generation antibacterial discovery (synthetic biology, genome mining, AI-enabled design). Other priority areas include adjuvant and combination therapies (β-lactamase inhibitors, efflux/potentiator strategies, membrane permeabilizers), anti-virulence and host-directed approaches and non-traditional antimicrobial modalities (phage/phage-derived agents, CRISPR-based antimicrobials, antimicrobial peptides, microbiome-based interventions), all of which focus on advancing innovative drug development.
Together, the contributions to this Special Issue will provide a focused roadmap for advancing innovative antibacterial discovery and development, with an emphasis on practical progress in innovative drug development to effectively mitigate antimicrobial resistance.
Dr. Zeinab Khalil
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antibiotic resistance
- antimicrobial drug discovery
- β-lactamases
- efflux pumps
- biofilms and persistence
- adjuvant/combination therapy
- anti-virulence strategies
- bacteriophage therapy
- AI-enabled antibiotic design
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