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Gels, Volume 10, Issue 4

April 2024 - 72 articles

Cover Story: Hydrogels based on cross-linking hydrazide-gelatin (hGel) with either oxidized hyaluronic acid (oxHA) or alginic acid (oxALG) were studied for their suitability to host hepatocyte cell cultures. Rheological studies demonstrated short gelation times and mechanical properties indicating suitability for liver cell culture. Gels were stable for more than 14 days, which is an important prerequisite for application. Studies with HepG2 hepatoblastoma cells showed that both types of gels were not cytotoxic and permitted proliferation of hepatocytes. These findings suggest the use of these hydrogels for establishing in vitro models of liver diseases and treatment, but also potential applications for engineering liver and other tissues. View this paper
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Articles (72)

  • Review
  • Open Access
38 Citations
7,392 Views
26 Pages

Liposome–Hydrogel Composites for Controlled Drug Delivery Applications

  • Roya Binaymotlagh,
  • Farid Hajareh Haghighi,
  • Laura Chronopoulou and
  • Cleofe Palocci

22 April 2024

Various controlled delivery systems (CDSs) have been developed to overcome the shortcomings of traditional drug formulations (tablets, capsules, syrups, ointments, etc.). Among innovative CDSs, hydrogels and liposomes have shown great promise for cli...

  • Article
  • Open Access
3 Citations
2,985 Views
22 Pages

22 April 2024

Poly(ether ether ketone) (PEEK) was found to form gels in the benign solvent 1,3-diphenylacetone (DPA). Gelation of PEEK in DPA was found to form an interconnected, strut-like morphology composed of polymer axialites. To our knowledge, this is the fi...

  • Article
  • Open Access
11 Citations
5,169 Views
18 Pages

Influence of Gelatin and Propolis Extract on Honey Gummy Jelly Properties: Optimization Using D-Optimal Mixture Design

  • Kultida Kaewpetch,
  • Saowapa Yolsuriyan,
  • Terd Disayathanoowat,
  • Patcharin Phokasem,
  • Taruedee Jannu,
  • Gerry Renaldi and
  • Rajnibhas Sukeaw Samakradhamrongthai

21 April 2024

Gelatin is commonly used as a gelling agent in gummy candy. Honey and bee products are valuable and rich sources of biologically active substances. In this study, the influence of gelatin and propolis extract on honey gummy jelly (HGJ) properties was...

  • Article
  • Open Access
25 Citations
5,529 Views
17 Pages

Active Fish Gelatin/Chitosan Blend Film Incorporated with Guava Leaf Powder Carbon Dots: Properties, Release and Antioxidant Activity

  • Gokulprasanth Murugan,
  • Krisana Nilsuwan,
  • Thummanoon Prodpran,
  • Arunachalasivamani Ponnusamy,
  • Jong-Whan Rhim,
  • Jun Tae Kim and
  • Soottawat Benjakul

21 April 2024

Active packaging is an innovative approach to prolonge the shelf-life of food products while ensuring their quality and safety. Carbon dots (CDs) from biomass as active fillers for biopolymer films have been introduced to improve their bioactivities...

  • Article
  • Open Access
3 Citations
3,106 Views
26 Pages

21 April 2024

Novel hyaluronic acid (HA) crosslinked with pentaerythritol tetra-acrylate (PT) injectable hydrogels was invented. These injectable hydrogel/dermal filler formulations were synthesised using HA and the acrylate PT as a crosslinker under basic pH cond...

  • Article
  • Open Access
3 Citations
2,364 Views
16 Pages

Polyhedral Oligomeric Sesquioxane Cross-Linked Chitosan-Based Multi-Effective Aerogel Preparation and Its Water-Driven Recovery Mechanism

  • Yang Liu,
  • Mingjian Ma,
  • Yuan Shen,
  • Zhengdong Zhao,
  • Xuefei Wang,
  • Jiaqi Wang,
  • Jiangbo Pan,
  • Di Wang,
  • Chengyu Wang and
  • Jian Li

20 April 2024

The use of environmentally friendly and non-toxic biomass-based interfacial solar water evaporators has been widely reported as a method for water purification in recent years. However, the poor stability of the water transport layer made from biomas...

  • Article
  • Open Access
6 Citations
3,396 Views
14 Pages

In Vitro Antibacterial and Anti-Inflammatory Properties of Imidazolium Poly(ionic liquids) Microspheres Loaded in GelMA-PEG Hydrogels

  • Chao Zhou,
  • Mengdi Sun,
  • Danni Wang,
  • Mingmei Yang,
  • Jia Ling Celestine Loh,
  • Yawen Xu and
  • Ruzhi Zhang

20 April 2024

Repairing damaged tissue caused by bacterial infection poses a significant challenge. Traditional antibacterial hydrogels typically incorporate various components such as metal antimicrobials, inorganic antimicrobials, organic antimicrobials, and mor...

  • Article
  • Open Access
3 Citations
2,921 Views
15 Pages

Determination of Density of Starch Hydrogel Microspheres from Sedimentation Experiments Using Non-Stokes Drag Coefficient

  • Margherita Cretella,
  • Mina Fazilati,
  • Nedim Krcic,
  • Ivan Argatov and
  • Vitaly Kocherbitov

19 April 2024

Sedimentation is an important property of colloidal systems that should be considered when designing pharmaceutical formulations. In pharmaceutical applications, sedimentation is normally described using Stokes’ law, which assumes laminar flow...

  • Article
  • Open Access
3 Citations
3,544 Views
25 Pages

Comprehensive Evaluation of Injectability Attributes in OxiFree™ Dermal Fillers: MaiLi® Product Variants and Clinical Case Reports

  • Patrick Micheels,
  • Alexandre Porcello,
  • Thierry Bezzola,
  • Daniel Perrenoud,
  • Marie-Odile Christen,
  • Lee Ann Applegate and
  • Alexis Laurent

19 April 2024

Dermal filler injectability is a critical factor for commercial product adoption by medical aesthetic professionals and for successful clinical administration. We have previously reported (in vitro and ex vivo) cross-linked hyaluronic acid (HA)-based...

  • Communication
  • Open Access
1 Citations
1,752 Views
9 Pages

18 April 2024

Dried porous materials can be found in a wide range of applications. So far, they are mostly prepared from inorganic or indigestible raw materials. The aim of the presented study was to provide a proof of concept for (a) the suitability of mealworm p...

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Gels - ISSN 2310-2861