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Bioengineering, Volume 10, Issue 1

January 2023 - 121 articles

Cover Story: The implementation of stem-cell-based organoid culture more than ten years ago started a development that created new avenues for diagnostic analyses and regenerative medicine. In order to achieve mechanistic insight into organoid formation and to support culture design, computational organoid models (COMs), i.e., in silico counterparts of organoids, have been developed in the last decade. While there is no doubt about the value of organoids in basic and applied cell biology, the question remains, what can we learn from their in silico counterparts? Here, we review the current state of the art of COMs and discuss perspectives for their application. View this paper
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Articles (121)

  • Article
  • Open Access
7 Citations
3,397 Views
16 Pages

Gene-Expression Analysis of Human Fibroblasts Affected by 3D-Printed Carboxylated Nanocellulose Constructs

  • Jennifer Rosendahl,
  • Chiara Zarna,
  • Joakim Håkansson and
  • Gary Chinga-Carrasco

Three-dimensional (3D) printing has emerged as a highly valuable tool to manufacture porous constructs. This has major advantages in, for example, tissue engineering, in which 3D scaffolds provide a microenvironment with adequate porosity for cell gr...

  • Review
  • Open Access
8 Citations
4,305 Views
13 Pages

In Vivo Biomechanical Measurements of the Cornea

  • Fanshu Li,
  • Kehao Wang and
  • Ziyuan Liu

In early corneal examinations, the relationships between the morphological and biomechanical features of the cornea were unclear. Although consistent links have been demonstrated between the two in certain cases, these are not valid in many diseased...

  • Review
  • Open Access
2 Citations
4,285 Views
26 Pages

Stroke is one of the leading causes of death and disability worldwide, so there is an urgent need to find a therapy for the tragic outcomes of this cerebrovascular disease. Stem cells appeared to be a good solution for many conditions, so different e...

  • Article
  • Open Access
51 Citations
8,083 Views
19 Pages

U-Net Model with Transfer Learning Model as a Backbone for Segmentation of Gastrointestinal Tract

  • Neha Sharma,
  • Sheifali Gupta,
  • Deepika Koundal,
  • Sultan Alyami,
  • Hani Alshahrani,
  • Yousef Asiri and
  • Asadullah Shaikh

The human gastrointestinal (GI) tract is an important part of the body. According to World Health Organization (WHO) research, GI tract infections kill 1.8 million people each year. In the year 2019, almost 5 million individuals were detected with ga...

  • Review
  • Open Access
7 Citations
3,767 Views
25 Pages

The endothelium plays a key role in the dynamic balance of hemodynamic, humoral and inflammatory processes in the human body. Its central importance and the resulting therapeutic concepts are the subject of ongoing research efforts and form the basis...

  • Article
  • Open Access
27 Citations
6,429 Views
12 Pages

Early intervention in kidney cancer helps to improve survival rates. Abdominal computed tomography (CT) is often used to diagnose renal masses. In clinical practice, the manual segmentation and quantification of organs and tumors are expensive and ti...

  • Article
  • Open Access
9 Citations
3,024 Views
16 Pages

ECG Measurement Uncertainty Based on Monte Carlo Approach: An Effective Analysis for a Successful Cardiac Health Monitoring System

  • Jackson Henrique Braga da Silva,
  • Paulo Cesar Cortez,
  • Senthil K. Jagatheesaperumal and
  • Victor Hugo C. de Albuquerque

Measurement uncertainty is one of the widespread concepts applied in scientific works, particularly to estimate the accuracy of measurement results and to evaluate the conformity of products and processes. In this work, we propose a methodology to an...

  • Article
  • Open Access
16 Citations
3,526 Views
18 Pages

Physical, Chemical and Functional Attributes of Neera Honey Infused Extrudates

  • Ravi Pandiselvam,
  • Liya T. Joseph,
  • M. R. Manikantan,
  • Anandu Chandra Khanashyam,
  • P. P. Shameena Beegum,
  • S. V. Ramesh,
  • D. Balasubramanian,
  • S. Neenu,
  • Murali Gopal and
  • A. C. Mathew
  • + 1 author

Owing to the demand for the consumption of healthy extrudates, this study explored the infusion of neera (coconut inflorescence sap) honey in rice flour, corn flour and coconut milk residue blend-based extrudates. Neera honey, the concentrated coconu...

  • Communication
  • Open Access
18 Citations
4,246 Views
8 Pages

Wearable Heart Rate Monitoring Device Communicating in 5G ISM Band for IoHT

  • Ilaria Marasco,
  • Giovanni Niro,
  • Suleyman Mahircan Demir,
  • Lorenzo Marzano,
  • Luca Fachechi,
  • Francesco Rizzi,
  • Danilo Demarchi,
  • Paolo Motto Ros,
  • Antonella D’Orazio and
  • Marco Grande
  • + 1 author

Advances in wearable device technology pave the way for wireless health monitoring for medical and non-medical applications. In this work, we present a wearable heart rate monitoring platform communicating in the sub-6GHz 5G ISM band. The proposed de...

  • Feature Paper
  • Article
  • Open Access
4 Citations
4,341 Views
16 Pages

Detection of Bacteria-Induced Early-Stage Dental Caries Using Three-Dimensional Mid-Infrared Thermophotonic Imaging

  • Robert Welch,
  • Koneswaran Sivagurunathan,
  • Pantea Tavakolian,
  • Kimberly Ngai,
  • Bo Huang,
  • Stephen Abrams,
  • Yoav Finer and
  • Andreas Mandelis

Tooth decay, or dental caries, is a widespread and costly disease that is reversible when detected early in its formation. Current dental caries diagnostic methods including X-ray imaging and intraoral examination lack the sensitivity and specificity...

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Bioengineering - ISSN 2306-5354