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Biology, Volume 14, Issue 10

October 2025 - 155 articles

Cover Story: This review explores how high-fat and ketogenic diets influence brain metabolism and contribute to neurodegenerative processes. Prolonged exposure to such diets alters glucose utilization, enhances oxidative stress, and triggers neuroinflammation in regions including the hippocampus, hypothalamus, and dopaminergic pathways. These biochemical disturbances may impair cognition and accelerate mechanisms underlying Alzheimer’s, Parkinson’s, and other neurodegenerative diseases. Despite certain neuroprotective effects of ketogenic diets, long-term safety and the balance between beneficial and harmful fat types remain uncertain, underscoring the need for further translational research. View this paper
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Articles (155)

  • Article
  • Open Access
342 Views
22 Pages

Comprehensive Analysis of the ARF Gene Family Reveals Their Roles in Chinese Chestnut (Castanea mollissima) Seed Kernel Development

  • Xili Liu,
  • Yun Li,
  • Manman Liang,
  • Dongsheng Wang,
  • Meng Wang,
  • Yi Lu,
  • Xia Liu,
  • Haie Zhang,
  • Xiangyu Wang and
  • Liyang Yu

21 October 2025

Auxin response factors (ARFs) are a class of significant transcription factors that play crucial roles in the regulation of plant growth and development. Although ARF genes have been extensively characterized in various plants, their functions in per...

  • Article
  • Open Access
246 Views
19 Pages

21 October 2025

PIWI-interacting RNAs (piRNAs) are small non-coding RNAs that interact with PIWI proteins and play essential roles in genome stability, gonadal development, and gametogenesis in animals. The Japanese flounder (Paralichthys olivaceus) is an important...

  • Article
  • Open Access
277 Views
20 Pages

21 October 2025

RNA editing is a crucial mechanism regulating gene expression in plant organellar genomes, which optimizes protein structures through base substitution and plays a vital role in plant growth, development, and stress adaptation. This study revises the...

  • Article
  • Open Access
311 Views
16 Pages

Research on the Mechanism of Hypoxia Tolerance of a Hybrid Fish Using Transcriptomics and Metabolomics

  • Yuhua Tang,
  • Jiayi Yang,
  • Chunchun Zhu,
  • Hong Zhang,
  • Li Hu,
  • Wenting Rao,
  • Xinxin Yu,
  • Ming Wen,
  • Min Tao and
  • Shaojun Liu

21 October 2025

The novel hybrid fish BTB, derived from crossing blunt snout bream (Megalobrama amblycephala, BSB) and topmouth culter (Culter alburnus, TC), exhibits markedly hypoxia tolerance in aquaculture. In this study, hypoxic treatment experiments confirmed t...

  • Article
  • Open Access
339 Views
19 Pages

CGF-Conditioned Medium Modulates Astrocytic Differentiation and Invasiveness in U87MG Glioblastoma Cells

  • Laura Giannotti,
  • Benedetta Di Chiara Stanca,
  • Francesco Spedicato,
  • Christian Demitri,
  • Eleonora Stanca,
  • Andrea Palermo,
  • Franco Ferrante,
  • Fabrizio Damiano,
  • Maria Antonietta De Sangro and
  • Luciano Abbruzzese
  • + 1 author

21 October 2025

Background: Glioblastoma (GBM) is a highly aggressive tumor characterized by elevated plasticity and poor differentiation. Platelet-derived preparations such as Concentrated Growth Factors (CGF) are rich in bioactive molecules, but their effects on t...

  • Article
  • Open Access
305 Views
21 Pages

21 October 2025

Saline aquaculture tailwater challenges conventional constructed wetlands (CWs) with their limited phosphorus (P) removal capacity. To address this, iron-carbon constructed wetlands (IC-CWs) were developed and operated under four salinity gradients (...

  • Review
  • Open Access
384 Views
18 Pages

21 October 2025

Plasmodium parasites are the causative agents of malaria and can infect humans and other vertebrates, impacting socioeconomic development and causing significant health issues globally. Plasmodium falciparum causes the most severe type of infection,...

  • Article
  • Open Access
379 Views
15 Pages

Characterization of Ingested Microplastics in a Regional Endemic Lizard Apathya cappadocica (Werner, 1902) from Türkiye

  • Cantekin Dursun,
  • Nagihan Demirci,
  • Kamil Candan,
  • Ahmet Gökay Korkmaz,
  • Ecem Büşra Hastürk,
  • Elif Yıldırım Caynak,
  • Çetin Ilgaz,
  • Yusuf Kumlutaş and
  • Serkan Gül

21 October 2025

This study investigated the presence, characteristics, and distribution of ingested microplastics (MPs) in Apathya cappadocica, a regional endemic lizard species. A total of 93 individuals were examined, and MPs were found in 19.35% (n = 18) of them....

  • Article
  • Open Access
280 Views
15 Pages

21 October 2025

The impact of substrates with different physicochemical properties on the response of rhizosphere fungi in rice to salt stress has not been fully explored. The purpose of this study is to reveal the adaptation characteristics of fungal colonies to sa...

  • Article
  • Open Access
734 Views
15 Pages

Efficient Serum-Free Rabies Virus Propagation Using BSR and Vero Cell Lines: A Comparative Evaluation of BioNOC II® Macrocarriers in the BelloStage™-3000 Bioreactor Versus Conventional Microcarriers

  • Zhanat Amanova,
  • Zhanna Sametova,
  • Sholpan Turyskeldy,
  • Alina Kurmasheva,
  • Ruslan Abitayev,
  • Abdurakhman Ussembay,
  • Zhanat Kondibaeva,
  • Dariya Toktyrova,
  • Dana Mazbayeva and
  • Sergazy Nurabayev
  • + 2 authors

21 October 2025

The rabies virus remains a significant public health threat, particularly in regions with limited access to vaccination. This study shows that the BelloStage™-3000 bioreactor, operating on the “Tide Motion” principle, in combination...

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Biology - ISSN 2079-7737Creative Common CC BY license