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Biology, Volume 14, Issue 9

September 2025 - 204 articles

Cover Story: Prostate cancer progression is strongly influenced by the tumour microenvironment, where low oxygen levels (hypoxia) promote aggressive behaviour. This study demonstrates that extracellular vesicles (EVs) released by metastatic prostate cancer cells under hypoxic stress carry altered cargo that reprograms less aggressive and non-malignant prostate cells. These EVs enhanced expression of hypoxia markers, activated Wnt signalling, induced epithelial–mesenchymal transition, with increased motility and invasion, hallmarks of metastatic potential. Our findings reveal that hypoxic tumour regions drive disease spread, highlighting EV-mediated signalling as a promising target for therapeutic intervention and biomarker discovery in prostate cancer. View this paper
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Articles (204)

  • Review
  • Open Access
1,246 Views
30 Pages

22 September 2025

Background: Hearing loss results from diverse biological insults along the auditory pathway, including sensory hair cell death, neural degeneration, and central auditory processing deficits. Implantable auditory neuroprostheses, such as cochlear and...

  • Article
  • Open Access
1 Citations
1,050 Views
38 Pages

Mathematical Modeling of Population Dynamics of Pollinators: A Survey

  • Fernando Huancas,
  • Anibal Coronel,
  • Esperanza Lozada and
  • Jorge Torres

22 September 2025

In this paper, we develop a systematic review of the existing literature on the mathematical modeling of several aspects of pollinators. We selected the MathSciNet and Wos databases and performed a search for the words “pollinator” and &l...

  • Article
  • Open Access
1,147 Views
24 Pages

Isolation, Identification, and Characterization of Novel Environmental Bacteria with Polyurethane-Degrading Activity

  • Marta Muñoz-Martí,
  • Virtudes Navarro Bañón,
  • Mª Carmen García-Poyo,
  • Carlos Castaño Forte,
  • Josefina Garrido,
  • Jose María Orts,
  • Andrea Huguet,
  • Jorge García-Hernández and
  • María Ángeles Castillo

22 September 2025

Polyurethane (PU) is a widely used plastic material whose persistence in the environment entails a serious ecological challenge. This study aimed to isolate and characterize environmental bacteria capable of degrading PU, using Impranil DLN as a mode...

  • Article
  • Open Access
551 Views
13 Pages

22 September 2025

In our previous study, adipose-derived stem cells (ASCs) cultured in a three-dimensional (3D) organotypic system exhibited mesenchymal-to-epithelial transition (MET) features, including cobblestone morphology and increased expression of E-cadherin an...

  • Article
  • Open Access
959 Views
16 Pages

Therapeutic Effects of Stem Cells from Human Exfoliated Deciduous Teeth and Their Conditioned Medium in Cisplatin-Induced Acute Kidney Injury: An In Vivo Study

  • Ardeshir Talebi,
  • Sahar Talebi,
  • Sara Nikpoor,
  • Nosrat Nourbakhsh,
  • Hossein Talebi,
  • Sareh Soroushzadeh,
  • Miguel Gómez-Polo and
  • Seyed Ali Mosaddad

22 September 2025

Background: Acute kidney injury (AKI) is a severe condition with high morbidity and mortality. Mesenchymal stem cells (MSCs) and their conditioned medium (MSCs-CM), containing extracellular vesicles (EVs), have shown therapeutic potential. This study...

  • Article
  • Open Access
569 Views
21 Pages

21 September 2025

Investigating the compositional characteristics of rhizosphere soil bacterial communities of Chinese seabuckthorn across different distribution areas and their relationship with habitat factors holds significant value for the development and utilizat...

  • Article
  • Open Access
506 Views
19 Pages

20 September 2025

The domestication of common carp in rice paddies (5–20 cm depth) is challenging, as the fish must withstand drastic fluctuations in temperature and dissolved oxygen, restricted movement, and bird predation without the option of diving. The effe...

  • Article
  • Open Access
764 Views
22 Pages

20 September 2025

Hypericum bilgehan bilgilii is a locally endemic species belonging to the genus Hypericum. Considering that the related plant has pharmacological and medicinal potential like other Hypericum species, this study has been conducted to determine its phy...

  • Article
  • Open Access
582 Views
11 Pages

Upregulation of Placental Vitamin D Receptor Expression in Gestational Diabetes Is Not Directly Related to Vitamin D Concentration

  • Marek Walkowiak,
  • Małgorzata Jamka,
  • Mateusz de Mezer,
  • Jakub Żurawski,
  • Paweł Gutaj and
  • Ewa Wender-Ożegowska

20 September 2025

Vitamin D plays a key role in pregnancy beyond calcium–phosphate regulation, modulating immune responses and glucose metabolism via the vitamin D receptor (VDR). Placental expression may be altered in gestational diabetes mellitus (GDM). This s...

  • Article
  • Open Access
493 Views
13 Pages

Provenance-Specific Height–Diameter Modeling for Chinese Fir: A Clustered Mixed-Effects Approach

  • Xiangrong Wu,
  • Yuhan Wang,
  • Yanjuan Lyu,
  • Wanrong Chen,
  • Ming Li and
  • Shuaichao Sun

20 September 2025

Chinese fir is the predominant afforestation species in southern China, exhibiting distinct provenances due to long-term climatic adaptation. This study utilized data from four surveys conducted at different ages in a provenance trial forest at Zhang...

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Biology - ISSN 2079-7737