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Journal of Clinical Medicine, Volume 12, Issue 13

2023 July-1 - 384 articles

Cover Story: Acute respiratory distress syndrome (ARDS) is a leading cause of disability and mortality worldwide, and while no specific etiologic interventions have been shown to improve outcomes, noninvasive and invasive respiratory support strategies are life-saving interventions that provide patients with time to recover. However, the inappropriate management of these strategies, which neglects the unique features of respiratory, lung, and chest wall mechanics, may result in disease progression, like patient self-inflicted lung injuries during spontaneous breathing. In this review, we provide an overview of noninvasive and invasive respiratory support strategies and discuss how identifying ARDS sub-phenotypes in daily practice can help clinicians to deliver personalized respiratory support and potentially improve the patients’ outcomes. View this paper
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Articles (384)

  • Review
  • Open Access
19 Citations
11,675 Views
10 Pages

It’s Time to Go Quantum in Medicine

  • Joseph Bisiani,
  • Adith Anugu and
  • Srinivas Pentyala

5 July 2023

As the field of medicine grows and expands, new scientific developments hold great promise for improving quality of care, clinical research, and the diagnosis and treatment of diseases. Quantum physics is a promising field that intersects with medici...

  • Review
  • Open Access
15 Citations
4,780 Views
14 Pages

Chronic Kidney Disease–Associated Pruritus and Quality of Life: Learning from Our Patients

  • Vicent Esteve-Simó,
  • Rosa Perez-Morales,
  • Juan Manuel Buades-Fuster,
  • Maria Dolores Arenas Jimenez,
  • Nuria Areste-Fosalba,
  • Guillermo Alcalde Bezhold,
  • Ana Blanco Santos,
  • Emilio Sanchez Álvarez,
  • Rafael Sanchez Villanueva and
  • Marian Goicoechea
  • + 3 authors

5 July 2023

Chronic kidney disease–associated pruritus is itching directly related to kidney disease that cannot be explained by any other condition. Despite technological advances in the different aspects of dialysis sessions and the best treatment for ch...

  • Article
  • Open Access
23 Citations
2,933 Views
10 Pages

Overall Accuracy of Radiological Digital Planning for Total Hip Arthroplasty in a Specialized Orthopaedics Hospital

  • Serban Dragosloveanu,
  • Mihnea-Alexandru Petre,
  • Mihai Emanuel Gherghe,
  • Dana-Georgiana Nedelea,
  • Cristian Scheau and
  • Romica Cergan

5 July 2023

Preoperative radiological planning is a key factor in the prediction of implant size and positioning that influences surgical time, the risk of complications, and functional outcomes. We have tested the accuracy of the digital templating performed in...

  • Review
  • Open Access
14 Citations
4,822 Views
10 Pages

Delays in Initiating Anti-Cancer Therapy for Early-Stage Breast Cancer—How Slow Can We Go?

  • Hikmat Abdel-Razeq,
  • Asem Mansour,
  • Sarah Edaily and
  • Abdulmajeed Dayyat

5 July 2023

Breast cancer is the most commonly diagnosed cancer among women worldwide, and is a leading cause of cancer-related deaths. When diagnosed at an early stage, appropriate and timely treatment results in a high cure rate and better quality of life. Del...

  • Article
  • Open Access
31 Citations
12,599 Views
11 Pages

Higher Prevalence of Adverse Childhood Experiences in Transgender Than in Cisgender Individuals: Results from a Single-Center Observational Study

  • Katharina Feil,
  • David Riedl,
  • Bettina Böttcher,
  • Martin Fuchs,
  • Klaus Kapelari,
  • Sofie Gräßer,
  • Bettina Toth and
  • Astrid Lampe

5 July 2023

Adverse childhood experiences (ACE) have been shown to have a tremendous negative impact on health outcomes later in life. This study presents data on the prevalence of ACEs, psychological distress, and trauma-related symptoms in transgender and gend...

  • Article
  • Open Access
3 Citations
6,005 Views
10 Pages

The 1450-nm Diode Laser Reduces Redness and Porphyrin Density: An Image-Based, Patient-Oriented Appraisal

  • Gong-Yau Chu,
  • Chieh-Chen Huang,
  • Nai-Hua Shih,
  • Chung-Hua Hsu and
  • Ching-Ying Wu

5 July 2023

Background: Acne vulgaris remains the leading dermatological condition. The efficacy of laser treatment has been supported by many clinical studies, but studies investigating its multidimensional action are lacking. Aim: To comprehensively investigat...

  • Article
  • Open Access
12 Citations
12,027 Views
17 Pages

5 July 2023

The diversity of patients pursuing facial aesthetic and facial gender-affirming surgery (FGAS) is increasing, yet there is a paucity of objective guidelines to facilitate surgical decision-making in patients of color. We conducted a quantitative anal...

  • Article
  • Open Access
6 Citations
5,388 Views
16 Pages

The Long-Term Outcome and Quality of Life after Replacement of the Ascending Aorta

  • Marwan Hamiko,
  • Katja Jahnel,
  • Julia Rogaczewski,
  • Myriam Schafigh,
  • Miriam Silaschi,
  • Andre Spaeth,
  • Markus Velten,
  • Wilhelm Roell,
  • Ali El-Sayed Ahmad and
  • Farhad Bakhtiary

5 July 2023

(1) Background: Despite optimal surgical therapy, replacement of the ascending aorta leads to a significant reduction in the quality of life (QoL). However, an optimal result includes maintaining and improving the QoL. The aim of our study was to eva...

  • Article
  • Open Access
21 Citations
3,488 Views
13 Pages

Repeatability and Reproducibility of Potential Ultrasonographic Bishop Score Parameters

  • Jakub Mlodawski,
  • Marta Mlodawska,
  • Justyna Plusajska,
  • Karolina Detka,
  • Katarzyna Bialek and
  • Grzegorz Swiercz

5 July 2023

Determination of the Bishop score (BS) is a traditional method of assessing the cervix in obstetrics and gynecology. This examination is characterized by subjectivity of assessment and low repeatability. In scientific studies intended to evaluate the...

  • Article
  • Open Access
2 Citations
2,685 Views
11 Pages

5 July 2023

Aims: The widespread use of three-dimensional (3D) mapping systems and echocardiography in the field of cardiac electrophysiology has made it possible to perform transseptal punctures (TSP) with low or no fluoroscopy. However, such attempts in adults...

  • Systematic Review
  • Open Access
4 Citations
3,535 Views
12 Pages

Blood Pressure Targets for Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis

  • Shir Lynn Lim,
  • Christopher Jer Wei Low,
  • Ryan Ruiyang Ling,
  • Rehena Sultana,
  • Victoria Yang,
  • Marcus E. H. Ong,
  • Yew Woon Chia,
  • Vijay Kumar Sharma and
  • Kollengode Ramanathan

5 July 2023

Background: With ideal mean arterial pressure (MAP) targets in resuscitated out-of-hospital cardiac arrest (OHCA) patients unknown, we performed a meta-analysis of randomised controlled trials (RCTs) to compare the effects of higher versus lower MAP...

  • Article
  • Open Access
1 Citations
2,591 Views
10 Pages

Influence of Different Bracket Adhesive Systems on Enamel Demineralization—An In Vitro Study

  • Christoph-Ludwig Hennig,
  • Simon Löhnert,
  • Ann Nitzsche,
  • Sandor Nietzsche,
  • Frank Steiniger,
  • Justus Marquetand,
  • Konrad Tolksdorf,
  • André Guellmar,
  • Bernd Sigusch and
  • Collin Jacobs

5 July 2023

Background: enamel demineralization is a common side effect of orthodontic therapy with fixed braces. The aim of the present in vitro study was to compare a conventional adhesive system and a modern adhesive system (APC Flash-Free [FF] technology) wi...

  • Article
  • Open Access
2 Citations
3,653 Views
11 Pages

5 July 2023

Recent studies have reported the impact of previous COVID-19 infection on the early clinical outcome after total knee arthroplasty (TKA). However, the timing of infection before the surgery was not constant and a study on patients with COVID-19 infec...

  • Feature Paper
  • Article
  • Open Access
13 Citations
3,143 Views
8 Pages

Effectiveness and Adherence of Dry Eye Patients Who Switched from Short- to Long-Acting Diquafosol Ophthalmic Solution

  • Sho Ishikawa,
  • Takanori Sasaki,
  • Takahumi Maruyama,
  • Koichiro Murayama and
  • Kei Shinoda

5 July 2023

Long-acting (lasting extend) diquafosol ophthalmic solution 3% (DQSLX) is administered three times daily versus six times daily for the currently approved diquafosol ophthalmic solution (DQS). We investigated the efficacy and adherence of switching f...

  • Article
  • Open Access
3 Citations
2,368 Views
11 Pages

5 July 2023

This retrospective study aimed to compare the accuracy of the pediatric dental surgeon’s estimated operative times for dental rehabilitation under general anesthesia (DRGA) in pediatric patients. This study population included 674 pediatric pat...

  • Article
  • Open Access
3,628 Views
12 Pages

5 July 2023

Herpes simplex virus (HSV) pneumonia is a serious and often fatal respiratory tract infection that occurs in immunocompromised individuals. The early detection of accurate risk stratification is essential in identifying patients who are at high risk...

  • Systematic Review
  • Open Access
26 Citations
12,863 Views
17 Pages

5 July 2023

A well-balanced metabolism means a lower risk for metabolism-related neuropsychiatric disorders. Leptin is a secretory adipokine involved in the central control of appetite that appears to play a role in the etiology of feeding-related disorders. Add...

  • Article
  • Open Access
6 Citations
3,262 Views
8 Pages

Vedolizumab Is Associated with Longer Drug Sustainability Compared to Infliximab in Moderate-to-Severe Ulcerative Colitis: Long-Term Real-World Cohort Data

  • Tom Konikoff,
  • Henit Yanai,
  • Dror Libchik,
  • Irit Avni-Biron,
  • Yifat Snir,
  • Hagar Banai,
  • Yelena Broytman,
  • Iris Dotan and
  • Jacob E. Ollech

4 July 2023

Background and Aim: Drug sustainability (DS) is a surrogate marker for treatment efficacy. We aimed to compare the DS of two main biologics used to treat moderate-to-severe ulcerative colitis (UC), infliximab (IFX) and vedolizumab (VDZ), in a real-wo...

  • Article
  • Open Access
8 Citations
5,419 Views
25 Pages

4 July 2023

Hearing loss is a prevalent health issue that affects individuals worldwide. Binaural hearing refers to the ability to integrate information received simultaneously from both ears, allowing individuals to identify, locate, and separate sound sources....

  • Article
  • Open Access
3 Citations
1,834 Views
12 Pages

Time-Dependent Changes of Klotho and FGF-23 Levels after Kidney Transplantation: Role of Cold Ischemia Time, Renal Function and Graft Inflammation

  • Teresa Vazquez-Sanchez,
  • Maria Dolores Sanchez-Niño,
  • Pedro Ruiz-Esteban,
  • Veronica López,
  • Myriam León,
  • Abelardo Caballero,
  • Juan Francisco Ruiz-Escalera,
  • Alberto Ortiz,
  • Armando Torres and
  • Domingo Hernandez
  • + 1 author

4 July 2023

We investigated the evolution of serum klotho (s-Kl) and FGF-23 during the first two years post-kidney transplantation (KT), considering the cold ischemia time (CIT), glomerular filtration rate (GFR) and graft subclinical inflammation (SCI). We under...

  • Article
  • Open Access
5 Citations
3,564 Views
11 Pages

4 July 2023

Patients with end-stage chronic obstructive pulmonary disease (COPD) often develop persistent hypoxic or hypercapnic respiratory failure, or a combination of both. Ventilatory support, in terms of a long-term high-flow nasal cannula (LT-HFNC) and lon...

  • Article
  • Open Access
3 Citations
2,266 Views
11 Pages

Clinical Application of the HCM-AF Risk Score in the Prediction of Clinical Outcomes of Polish Patients with Hypertrophic Cardiomyopathy

  • Maria Stec,
  • Agata Suleja,
  • Daniel Gondko,
  • Wiktoria Kuczmik,
  • Jakub Roman,
  • Dominika Dziadosz,
  • Krzysztof Szydło and
  • Katarzyna Mizia-Stec

4 July 2023

The recently introduced HCM-AF Risk Calculator allows the prognosis of atrial fibrillation (AF) occurrence in hypertrophic cardiomyopathy (HCM) patients. The aim of this study was to assess the clinical application of the HCM-AF Risk Score in the pre...

  • Article
  • Open Access
7 Citations
3,479 Views
13 Pages

Effect of COVID-19 on Blood Pressure Profile and Oxygen Pulse during and after the Cardiopulmonary Exercise Test in Healthy Adults

  • Kamila Miętkiewska-Szwacka,
  • Remigiusz Domin,
  • Małgorzata Kwissa,
  • Mikołaj Żołyński,
  • Jan Niziński,
  • Elżbieta Turska and
  • Maciej Cymerys

4 July 2023

Several reports have shown the impact of COVID-19 history on exercise capacity. This study compared the blood pressure (BP) response and oxygen pulse (O2 pulse) characteristics in normotensive patients with and without a history of COVID-19 during th...

  • Editorial
  • Open Access
1 Citations
1,915 Views
5 Pages

4 July 2023

Mental disorders are the leading cause of diminished lifespans worldwide and make up 5 of the top 10 most significant causes of disability [...]

  • Editorial
  • Open Access
1,994 Views
6 Pages

4 July 2023

Benign conditions of the lower urinary tract, including benign prostatic hyperplasia, overactive bladder syndrome, and stress urinary incontinence, are frequent in the general population. Despite their benign nature, they have major adverse effects o...

  • Systematic Review
  • Open Access
7 Citations
4,051 Views
14 Pages

Biomarkers Associated with Thrombosis in Patients with Peripherally Inserted Central Catheter: A Systematic Review and Meta-Analysis

  • Patrícia Cristina Cardoso,
  • Eneida Rejane Rabelo-Silva,
  • Patricia Martins Bock,
  • Vineet Chopra and
  • Marco Aurélio Lumertz Saffi

4 July 2023

Background: The measurement and identification of plasma biomarkers can support the estimation of risk and diagnosis of deep vein thrombosis (DVT) associated with the use of a peripherally inserted central catheter (PICC). Objectives: This systematic...

  • Article
  • Open Access
6 Citations
2,684 Views
14 Pages

4 July 2023

In this study, we sought to investigate the occurrence of appropriate implantable cardioverter-defibrillator (ICD) therapies and inappropriate shocks in secondary prevention ICD recipients with ventricular arrhythmia of unclear cause and ventricular...

  • Article
  • Open Access
1 Citations
2,908 Views
11 Pages

AMH in Males: Effects of Body Size and Composition on Serum AMH Levels

  • Veronika Tandl,
  • Christoph Haudum,
  • Katharina Eberhard,
  • Barbara Hutz,
  • Ines Foessl,
  • Ewald Kolesnik,
  • Andreas Zirlik,
  • Dirk von Lewinski,
  • Daniel Scherr and
  • Barbara Obermayer-Pietsch
  • + 2 authors

4 July 2023

Serum concentrations of anti-Müllerian hormone (AMH) have been found to decrease with increasing body mass index (BMI) in many studies. It is not yet clear whether this stems from an adverse effect of adiposity on AMH production, or from dilutio...

  • Article
  • Open Access
18 Citations
9,853 Views
8 Pages

A Simple Equation to Estimate Maximal Oxygen Uptake in Older Adults Using the 6 min Walk Test, Sex, Age and Body Mass Index

  • Peter Šagát,
  • Zvonimir Kalčik,
  • Peter Bartik,
  • Ľuboslav Šiška and
  • Lovro Štefan

4 July 2023

Purpose: The 6 min walk test (6MWT) is used in clinical and epidemiological practice as a simple tool to evaluate the maximal aerobic exercise capacity (VO2max). To date, little evidence has been provided regarding regression equation models to predi...

  • Brief Report
  • Open Access
2 Citations
2,385 Views
10 Pages

Clinical Outcome of Kidney Transplant Recipients with C1q-Binding De Novo Donor Specific Antibodies: A Single-Center Experience

  • Smaragdi Marinaki,
  • Angeliki Vittoraki,
  • Stathis Tsiakas,
  • Ioannis Kofotolios,
  • Maria Darema,
  • Sofia Ioannou,
  • Kalliopi Vallianou and
  • John Boletis

4 July 2023

Complement activation by HLA antibodies is a key component of immune-mediated graft injury. We examined the clinical outcomes of kidney transplant recipients with complement-fixing de novo donor-specific antibodies (dnDSA) who were followed in our ce...

  • Article
  • Open Access
24 Citations
6,990 Views
14 Pages

Long-Term Outcomes of the PRESERFLO MicroShunt Implant in a Heterogeneous Glaucoma Cohort

  • Jens Julian Storp,
  • Friederike Elisabeth Vietmeier,
  • Ralph-Laurent Merté,
  • Raphael Koch,
  • Julian Alexander Zimmermann,
  • Nicole Eter and
  • Viktoria Constanze Brücher

4 July 2023

The Preserflo MicroShunt represents a novel glaucoma treatment device, necessitating long-term follow-up data to accurately assess its efficacy. The aim of this study is to report real-world data of a heterogenous glaucoma cohort who received Preserf...

  • Article
  • Open Access
1 Citations
3,066 Views
13 Pages

Smoking and COPD Knowledge in the General Spanish Population: A CONOCEPOC Study

  • Juan Luis Rodríguez Hermosa,
  • Marc Miravitlles,
  • José Luis López-Campos and
  • Myriam Calle Rubio

4 July 2023

Background: The objective of this analysis is to evaluate tobacco use and the level of chronic obstructive pulmonary disease (COPD) knowledge among the general adult population in Spain and to compare these results to those obtained in the 2011 surve...

  • Article
  • Open Access
11 Citations
3,124 Views
17 Pages

Three-Dimensional Characterization of Aortic Root Motion by Vascular Deformation Mapping

  • Taeouk Kim,
  • Nic S. Tjahjadi,
  • Xuehuan He,
  • JA van Herwaarden,
  • Himanshu J. Patel,
  • Nicholas S. Burris and
  • C. Alberto Figueroa

4 July 2023

The aorta is in constant motion due to the combination of cyclic loading and unloading with its mechanical coupling to the contractile left ventricle (LV) myocardium. This aortic root motion has been proposed as a marker for aortic disease progressio...

  • Article
  • Open Access
3 Citations
1,910 Views
14 Pages

Interleukin 12 in the Acute Phase of the Immune Response after Excimer Laser Treatment

  • Mirko Resan,
  • Zeljka Cvejic,
  • Igor Pancevski,
  • Gabriele Thumann,
  • Martina Kropp,
  • Ivo Guber,
  • Dragana Ristic,
  • Danilo Vojvodic and
  • Bojan Pajic

4 July 2023

Background and objectives: The aim of the research was to investigate the differences in the concentrations of IL-12, IL-4, IL-10, and IFN-γ in tears after LASIK and PRK procedures. Materials and methods: The study included 68 myopic eyes up to...

  • Feature Paper
  • Case Report
  • Open Access
3 Citations
3,661 Views
8 Pages

Intestinal Obstruction for Anisakiasis: Surgical and Physical Therapy Treatment

  • Fernando Cózar-Bernal,
  • Jorge Góngora-Rodríguez,
  • Carmen Ayala-Martínez,
  • Francisco Javier Martín-Vega,
  • Maria Jesus Vinolo-Gil and
  • Manuel Rodríguez-Huguet

4 July 2023

Anisakiasis, a zoonotic disease that can lead to small intestine obstruction, has seen a significant rise in Spain. The country has become the first in Europe with an annual incidence of 8000 cases, primarily due to the popularity of consuming exotic...

  • Article
  • Open Access
2,716 Views
18 Pages

Hybrid Molecules of Benzylguanidine and the Alkylating Group of Melphalan: Synthesis and Effects on Neuroblastoma Cells

  • Gernot Bruchelt,
  • Chihab Klose,
  • Matthias Lischka,
  • Marietta Brandes,
  • Rupert Handgretinger and
  • Reinhard Brueckner

3 July 2023

The therapy of neuroblastoma relies, amongst other things, on administering chemotherapeutics and radioactive compounds, e.g., the (meta-iodobenzyl)guanidine [131I]mIBG. For special applications (conditioning before stem cell transplantation), busulf...

  • Article
  • Open Access
6 Citations
3,485 Views
12 Pages

3 July 2023

Background: The increasing prevalence of type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD) states a serious problem for public health. The introduction of effective methods of treatment and prevention is crucial to avoid c...

  • Systematic Review
  • Open Access
27 Citations
19,819 Views
22 Pages

Impacts of Whole-Body Vibration on Muscle Strength, Power, and Endurance in Older Adults: A Systematic Review and Meta-Analysis

  • Raphael Gonçalves de Oliveira,
  • Heloísa Maria Elaine Licha Coutinho,
  • Maiara Naldi Mansano Martins,
  • Mario Bernardo-Filho,
  • Danúbia da Cunha de Sá-Caputo,
  • Laís Campos de Oliveira and
  • Redha Taiar

3 July 2023

Background: Randomized clinical trials (RCTs) were conducted to identify the effectiveness of whole-body vibration (WBV) on strength, power, and muscular endurance in older adults. However, the results of different studies are contradictory. Objectiv...

  • Article
  • Open Access
10 Citations
3,507 Views
18 Pages

Effect of COVID-19 Pandemic on Patients Who Have Undergone Liver Transplantation: Retrospective Cohort Study

  • Sami Akbulut,
  • Fatma Hilal Yagin,
  • Tevfik Tolga Sahin,
  • Ibrahim Umar Garzali,
  • Adem Tuncer,
  • Musap Akyuz,
  • Nazlican Bagci,
  • Bora Barut,
  • Selver Unsal and
  • Sezai Yilmaz
  • + 6 authors

3 July 2023

Background: In liver transplant (LT) recipients, immunosuppressive therapy may potentially increase the risk of severe COVID-19 and may increase the mortality in patients. However, studies have shown conflicting results, with various studies reportin...

  • Review
  • Open Access
35 Citations
6,186 Views
13 Pages

Congenital Cytomegalovirus and Hearing Loss: The State of the Art

  • Mirko Aldè,
  • Sandro Binda,
  • Valeria Primache,
  • Laura Pellegrinelli,
  • Elena Pariani,
  • Fabrizio Pregliasco,
  • Federica Di Berardino,
  • Giovanna Cantarella and
  • Umberto Ambrosetti

3 July 2023

In developed countries, congenital cytomegalovirus (cCMV) infection is the most common congenital viral infection, representing the leading non-genetic cause of sensorineural hearing loss (HL). Diagnosis of cCMV infection can be performed by detectio...

  • Article
  • Open Access
12 Citations
3,091 Views
9 Pages

Fetal Heart Rate < 3rd Percentile for Gestational Age Can Be a Marker of Inherited Arrhythmia Syndromes

  • Nadia Chaudhry-Waterman,
  • Bharat Dara,
  • Emily Bucholz,
  • Camila Londono Obregon,
  • Michelle Grenier,
  • Kristen Snyder and
  • Bettina F. Cuneo

3 July 2023

Background: Repeated fetal heart rates (FHR) < 3rd percentile for gestational age (GA) with 1:1 atrioventricular conduction (sinus bradycardia) can be a marker for long QT syndrome. We hypothesized that other inherited arrhythmia syndromes might p...

  • Article
  • Open Access
2 Citations
2,079 Views
10 Pages

Efficacy of Serum Ferritin–Zinc Ratio for Predicting Advanced Liver Fibrosis in Patients with Autoimmune Hepatitis

  • Kei Moriya,
  • Shinya Sato,
  • Norihisa Nishimura,
  • Hideto Kawaratani,
  • Hiroaki Takaya,
  • Kosuke Kaji,
  • Tadashi Namisaki,
  • Masakazu Uejima,
  • Shinsaku Nagamatsu and
  • Hitoshi Yoshiji
  • + 1 author

3 July 2023

Background/Aims: The search for noninvasive biomarkers that can efficiently estimate the extent of liver fibrosis progression is ongoing. Although Fibrosis-4 (FIB-4), the aspartate transaminase-to-platelet ratio index (APRI), and the Forns index have...

  • Article
  • Open Access
3 Citations
2,425 Views
11 Pages

3 July 2023

We evaluated baseline lower urinary tract symptoms (LUTS) and sexual dysfunction in patients with newly diagnosed localized prostate cancer. Data were obtained from a cohort registry of patients with localized prostate cancer scheduled for radical pr...

  • Brief Report
  • Open Access
10 Citations
3,678 Views
9 Pages

Balance Disorders in People with History of COVID-19 in Light of Posturographic Tests

  • Zofia Dzięcioł-Anikiej,
  • Agnieszka Dakowicz,
  • Janusz Dzięcioł,
  • Szymon Kopko,
  • Diana Moskal-Jasińska,
  • Aleksandra Gawlikowska-Sroka,
  • Anna Kuryliszyn-Moskal and
  • Amanda Maria Kostro

3 July 2023

Coronavirus disease-19 (COVID-19), resulting from infection with the SARS-CoV-2 virus, causes not only flu-like symptoms, such as fever, aches, or a dry cough, but also affects the sensory system, leading to a loss of smell and taste or to neurologic...

  • Article
  • Open Access
4 Citations
4,604 Views
14 Pages

Long-Term Outcomes after Multimodal Treatment for Clival Chordoma: Efficacy of the Endonasal Transclival Approach with Early Adjuvant Radiation Therapy

  • Hyun Dong Yoo,
  • Jong Chul Chung,
  • Ki Seok Park,
  • Seung Young Chung,
  • Moon Sun Park,
  • Seungjun Ryu and
  • Seong Min Kim

3 July 2023

This study investigates the long-term outcomes of clival chordoma patients treated with the endonasal transclival approach (ETCA) and early adjuvant radiation therapy. A retrospective review of 17 patients (2002–2013) showed a 10-year progressi...

  • Article
  • Open Access
17 Citations
2,888 Views
10 Pages

Empagliflozin Reduces Interleukin-6 Levels in Patients with Heart Failure

  • Michael Gotzmann,
  • Pauline Henk,
  • Ulrik Stervbo,
  • Arturo Blázquez-Navarro,
  • Andreas Mügge,
  • Nina Babel and
  • Timm H. Westhoff

3 July 2023

Background: The inhibition of sodium-glucose co-transporter 2 (SGLT-2) has been shown to be beneficial in the treatment of diabetic and non-diabetic patients with heart failure. The underlying mechanisms are incompletely understood. The present prosp...

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J. Clin. Med. - ISSN 2077-0383