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Pathogens, Volume 8, Issue 3

September 2019 - 70 articles

Cover Story: Persistent infection is a characteristic of babesiosis, a worldwide, emerging tick-borne disease caused by members of the genus Babesia. The persistence of Babesia infection in reservoir hosts increases the probability of transmission of these pathogens. Babesia microti, the major cause of human babesiosis, can asymptomatically infect immunocompetent individuals for up to two years. Infected blood donors may transmit the pathogen to another person through blood transfusion. Immunocompromised patients, including those with asplenia, HIV/AIDS, malignancy, or on immunosuppressive drugs, often experience severe disease that may relapse up to two years after treatment, despite anti-Babesia therapy. The health burden of persistent babesiosis can be minimized by the development of novel therapeutic and preventive measures, such as new antimicrobials, early detection methods, tick-avoidance, and blood donor screening.
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  • Articles (70)

    • Article
    • Open Access
    6 Citations
    5,408 Views
    12 Pages

    18 September 2019

    Heterobasidion annosum sensu lato is a species complex of pathogenic white-rot wood decay fungi which cause root and butt rot in conifer and hardwood species across the Northern hemisphere. Annual losses to forest managers are valued in the billions...

    • Article
    • Open Access
    18 Citations
    6,180 Views
    17 Pages

    18 September 2019

    Advancements in next-generation sequencing techniques have led to a substantial increase in the genomic information available for analyses in evolutionary biology. As such, this data requires the exponential growth in bioinformatic methods and expert...

    • Article
    • Open Access
    17 Citations
    6,828 Views
    14 Pages

    17 September 2019

    The influence of the strain on the ability of Salmonella enterica to form biofilms on polystyrene was investigated by confocal laser scanning microscopy. The effects of sodium hypochlorite with 10% active chlorine (SHY; 25,000, 50,000, or 100,000 ppm...

    • Article
    • Open Access
    25 Citations
    5,296 Views
    8 Pages

    First Molecular Evidence of Anaplasma bovis and Anaplasma phagocytophilum in Bovine from Central Punjab, Pakistan

    • Naveed Iqbal,
    • Muhammad Uzair Mukhtar,
    • Jifei Yang,
    • Muhammad Sohail Sajid,
    • Qingli Niu,
    • Guiquan Guan,
    • Zhijie Liu and
    • Hong Yin

    17 September 2019

    Obligate intracellular bacteria belonging to the genus Anaplasma spp. are responsible for causing a hemolytic disease called anaplasmosis in animals, as well as in humans. This study was aimed at the molecular identification and genetic analysis of r...

    • Article
    • Open Access
    17 Citations
    4,247 Views
    13 Pages

    Genetic Profiling of Aggregatibacter actinomycetemcomitans Serotype B Isolated from Periodontitis Patients Living in Sweden

    • Anders Johansson,
    • Rolf Claesson,
    • Carola Höglund Åberg,
    • Dorte Haubek,
    • Mark Lindholm,
    • Sarah Jasim and
    • Jan Oscarsson

    17 September 2019

    The bacterium Aggregatibacter actinomycetemcomitans is associated with aggressive forms of periodontitis and with systemic diseases, such as endocarditis. By assessing a Ghanaian longitudinal adolescent cohort, we earlier recognized the cagE gene as...

    • Article
    • Open Access
    28 Citations
    7,417 Views
    13 Pages

    Development of Conventional Multiplex PCR: A Rapid Technique for Simultaneous Detection of Soil-Transmitted Helminths

    • Vivornpun Sanprasert,
    • Ruthairat Kerdkaew,
    • Siriporn Srirungruang,
    • Sarit Charuchaibovorn,
    • Kobpat Phadungsaksawasdi and
    • Surang Nuchprayoon

    16 September 2019

    Soil-transmitted helminths (STHs) are the most common intestinal parasites infecting humans worldwide. STH infections are a major cause of morbidity and disability. Accurate diagnostic tools are pivotal for assessing the exact prevalence of parasitic...

    • Article
    • Open Access
    18 Citations
    5,078 Views
    10 Pages

    Chikungunya Virus Transmission at Low Temperature by Aedes albopictus Mosquitoes

    • B. M. C. Randika Wimalasiri-Yapa,
    • Liesel Stassen,
    • Wenbiao Hu,
    • Laith Yakob,
    • Elizabeth A. McGraw,
    • Alyssa T. Pyke,
    • Cassie C. Jansen,
    • Gregor J. Devine and
    • Francesca D. Frentiu

    12 September 2019

    Aedes albopictus is an important vector of chikungunya virus (CHIKV). In Australia, Ae. albopictus is currently only known to be present on the islands of the Torres Strait but, should it invade the mainland, it is projected to spread to temperate re...

    • Article
    • Open Access
    40 Citations
    6,776 Views
    20 Pages

    Antifungal and Antivirulence Activity of Vaginal Lactobacillus Spp. Products against Candida Vaginal Isolates

    • Camilla Itapary dos Santos,
    • Yasmine Ramos França,
    • Carmem Duarte Lima Campos,
    • Maria Rosa Quaresma Bomfim,
    • Bruna Oliveira Melo,
    • Rodrigo Assunção Holanda,
    • Vera Lucia Santos,
    • Sílvio Gomes Monteiro,
    • Eduardo Buozzi Moffa and
    • Andrea Souza Monteiro
    • + 2 authors

    12 September 2019

    Candida yeasts are generally found in the vaginal microbiota; however, disruption of the balance maintained by host factors and microorganisms results in vulvovaginal candidiasis (VVC). This study evaluated the antagonistic activity of vaginal Lactob...

    • Article
    • Open Access
    4 Citations
    4,233 Views
    11 Pages

    Comparative Study of CDST & Multiplex PCR to Detect MBL Producing Gram-Negative Bacilli among VAP Patients Admitted in a Public Medical College Hospital of Bangladesh

    • Tanzina Nusrat,
    • Nasima Akter,
    • Mainul Haque,
    • Nor Azlina A. Rahman,
    • Arup Kanti Dewanjee,
    • Shakeel Ahmed and
    • Diana Thecla D. Rozario

    12 September 2019

    Background: Ventilator-associated pneumonia (VAP) is the most common nosocomial infection in intensive care units (ICU), which accounts for 25% of all ICU infection. Documenting carbapenem-resistant gram-negative bacilli is very important as these st...

    • Review
    • Open Access
    37 Citations
    7,514 Views
    10 Pages

    12 September 2019

    Flavivirus replication in host cells requires the formation of replication and assembly complexes on the cytoplasmic side of the endoplasmic reticulum (ER) membrane. These complexes consist of an ER membrane, viral proteins, and host proteins. Genome...

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    Pathogens - ISSN 2076-0817