Special Issue "Chikungunya Virus Infections"
Deadline for manuscript submissions: closed (1 July 2019).
Interests: virus–host interactions; immune activation and evasion; therapeutic interventions
Special Issues and Collections in MDPI journals
Since its re-emergence in 2004, chikungunya virus (CHIKV) has caused several large outbreaks, infecting millions of people. Although CHIKV infection is rarely lethal, the severe and sometimes persistent arthralgia and arthritis it causes pose a significant economic burden on healthcare systems. CHIKV has a broad geographic distribution, potentially putting millions at risk for infection. Due to the expanding geographic spread of competent CHIKV vectors, infected travelers can spark new outbreaks in previously untouched areas. Presently, no licensed vaccines or specific antivirals are available to prevent or combat CHIKV infection. Therefore, developing novel therapeutic interventions should be an important priority. In order to do so, extensive knowledge of the underlying molecular mechanisms of CHIKV infection is required. Despite major discoveries in recent years, there are still important gaps in our understanding of CHIKV replication. These include, but are not limited to, a complete picture of the molecular interactions of CHIKV with both its mosquito and human host, and a detailed understanding of the mechanisms underlying transmission and pathogenesis. Enhanced insight into these dynamics is required to effectively combat the emergence and spread of the virus. In addition, a detailed understanding of the immune responses involved in chronic disease and those required for effective vaccines remain a priority.
This Special Issue will cover a wide range of topics focusing on chikungunya infection and immunity, and aims to help fill the gaps in our current understanding of CHIKV. All types of articles will be considered for publication, including short reports, primary research articles, and reviews.
Dr. Florine E.M. Scholte
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Chikungunya virus
- Virus-host interactions
- Therapeutic interventions
- Virulence factors
- Immune activation and evasion