2026 September-1 - 204 articles
Background/Objectives: To evaluate the impact of dental laboratory material overlays on metal artifact reduction in multidetector computed tomography (MDCT) of the oral cavity across different CT protocols and reconstruction algorithms. Methods: An a...
Background: Smartphone-based store-and-forward teledermatology (SAF-TD) has emerged as a potential approach to improving access to dermatological care. Patient-initiated SAF-TD systems, which enable direct image submission to dermatology specialists,...
Background/Objectives: Diabetic retinopathy is a major cause of preventable vision loss worldwide, making early and accurate disease grading crucial for timely treatment. Although convolutional neural network (CNN)- and transformer-based architecture...
Background/Objectives: Helsmoortel–Van der Aa syndrome (HVDAS), or ADNP syndrome, is a neurodevelopmental disorder characterized by cognitive deficits, dysmorphic features, and multisystem involvement. While typically arising de novo, familial...
Background/Objectives: Accurate delineation of the optic disc and optic cup in retinal fundus photographs is a prerequisite for automated glaucoma screening. While encoder–decoder segmentation models have advanced considerably, the contribution...
Background/Objectives: Cardiovascular diseases (CVDs) represent the foremost public health challenge of recent days. According to the World Health Organization (WHO), nearly 32% of people die from CVDs each year. This paper introduces a quantum-inspi...
Background/Objectives: Dental implants are a reliable treatment for tooth loss, but identifying the implant brand when patient records are unavailable remains a clinical challenge that complicates prosthetic repair and complication management. This s...
We sincerely thank the author for the thoughtful and constructive comment highlighting the potential complementary role of cellular stress markers in the prognostic assessment of patients with ST-segment elevation myocardial infarction (STEMI) [...]
Background/Objectives: Comatose patients admitted to intensive care represent a heterogeneous critical population, in which prognosis can be influenced by the interaction between inflammation, coagulation, tissue damage and respiratory dysfunction. T...
I read with interest the recently published article by Magureanu et al [...]
Background: Recovery after hip fragility fracture surgery is heterogeneous. Explainable machine learning (ML) may help identify factors associated with short-term recovery during inpatient rehabilitation. Methods: This retrospective exploratory cohor...
Background: Our objective was to evaluate the prognostic value of TROP2 and HER3 expression in patients with early-stage cervical carcinoma undergoing primary surgical treatment. Methods: We retrospectively analyzed 54 patients with FIGO 2018 stage I...
Objectives: To evaluate the accuracy and usability of emergency department (ED) clinician-assigned diagnostic codes across all four Tasmanian public hospitals. Methods: We conducted a retrospective study of 300 ED presentations from all four public E...
Background: The forensic diagnosis of drowning lacks pathognomonic signs, and visceral weight-based indices normalised to spleen or heart weight have shown variable discriminant performance. We assessed a height-normalised revised Drowning Index (rDI...
Background and Objectives: p53 signatures are segments of strongly p53-immunoreactive secretory epithelium in the fallopian tube. We tested whether fixed pathology-pretrained image representations could classify three ordered categories reconstructed...
Background: People living with HIV (PLWH) are at increased risk of cardiovascular disease (CVD). Aortic stiffness measured with carotid-femoral pulse wave velocity (PWV) is a validated predictor of CVD and has been shown to be elevated in PLWH at HIV...
Background and Objectives: Ménétrier’s disease (MD) is an exceptionally rare hypertrophic gastropathy characterized by foveolar hyperplasia, gastric acid suppression, and protein-losing enteropathy. Congenital gallbladder duplicat...
Background: The management of benign thyroid nodules causing compressive symptoms, cosmetic concerns, or rapid growth in older adults is challenging because of multimorbidity and increased surgical risk. Ultrasound-guided microwave ablation (MWA) is...
Sleep bruxism is the rhythmic or nonrhythmic masticatory muscle activity that occurs during sleep. It is conventionally diagnosed by a rule-based algorithm. Candidate muscle bursts are flagged against a fixed electromyographic (EMG) amplitude thresho...
Objectives: To assess the technical feasibility and interobserver reliability of transrectal biplane ultrasound with external cotton-swab marking of the urethral orifice after transobturator mid-urethral sling surgery, and secondarily to describe dyn...
Background: Preeclampsia is a leading cause of maternal and perinatal morbidity, characterized by angiogenic imbalance reflected in the sFlt-1/PlGF ratio. While the Endothelial Activation and Stress Index (EASIX), a composite score of lactate dehydro...
Objective: To evaluate the feasibility of simulated ultra-low-dose CT (ULD-CT) enhanced with deep learning denoising (DLD) for detecting pelvic and hip fractures. Method: This Institutional Review Board-approved retrospective study was performed at a...
Background/Objectives: Cerebral small vessel disease (SVD) is a heterogeneous condition in which similar conventional MRI findings may be associated with different clinical manifestations and pathogenetic mechanisms. Previously, hierarchical clusteri...
Background/Objectives: Norway has transitioned from cytology-based to HPV-based cervical screening. We examined long-term trends in histologically confirmed cervical intraepithelial neoplasia grade 2 or worse (CIN2+), grade 3 or worse (CIN3+), and ce...
Lung cancer ranks first among all malignancies in both incidence and mortality worldwide, and precise target volume delineation is the key to ensuring the efficacy and safety of radiotherapy. Conventional CT imaging has significant limitations in dis...
Background: Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors with highly variable biological behavior. Somatostatin receptor (SSTR)-based imaging with 68Ga-DOTATATE PET/CT has become an important functional imaging modality...
Amyotrophic lateral sclerosis (ALS) usually enters diagnostic pathways after motor symptoms emerge, by which time neural injury has been ongoing. Long-term hereditary ALS cohorts show that some pathogenic-variant carriers may show elevated neurofilam...
Background/Objectives: First NIBUT, Average NIBUT, and tear meniscus height (TMH) are routinely used to characterize tear film stability and tear volume at individual visits, whereas their longitudinal behavior across the hospital-attending populatio...
Background/Objectives: Transaxillary access (TAx) is an established alternative to transfemoral access (TF) for transcatheter aortic valve implantation (TAVI) in patients with unfavorable iliofemoral anatomy. While TAx-TAVI has been increasingly adop...
Background and Clinical Significance: Penile carcinoma is a rare malignancy in developed countries, yet it remains associated with significant morbidity due to its aggressive local behavior and potential for lymphatic dissemination. Human Papillomavi...
Background/Objectives: Pretreatment imaging may help estimate axillary response after neoadjuvant chemotherapy (NAC) in clinically node-positive (cN+) breast cancer. This study compared routinely available magnetic resonance imaging (MRI) and ultraso...
Background/Objectives: The TEG® 6s is a hemostasis analyzer system used to assess viscoelastic properties of whole blood. Although it provides rapid and comprehensive insights, interpreting thromboelastography tracings requires robust clinical tr...
Orofacial pain is a complex and multifactorial condition that affects quality of life and presents important diagnostic and therapeutic challenges. Advances in neuroimaging techniques have enabled the investigation of nervous system alterations assoc...
Background/Objectives: Lung cancer in Romania is characterized by high mortality and a lack of organized screening programs, resulting in frequent late-stage diagnoses. This study evaluates diagnostic patterns, stage distribution, and screening eligi...
Background/Objectives: Early risk stratification is essential in pulmonary embolism (PE), but a simple tool integrating routinely available clinical and laboratory variables is lacking. We aimed to develop a simple score for predicting 30-day mortali...
Background: Perioperative antithrombotic management is a complex and high-risk aspect of anesthesia practice, requiring a careful balance between bleeding and thromboembolic risks. Large language models (LLMs) are increasingly explored for clinical d...
Background: Congenital heart block (CHB) is a severe disorder, with an estimated incidence of 1 in 20,000 live births. In most cases, the underlying pathophysiology involves transplacental transfer of maternal anti-Ro/SSA and/or anti-La/SSB antibodie...
Inflammatory and nested testicular sex cord tumor (IN-TSCT) is a recently recognized, rare testicular sex cord–stromal neoplasm characterized by a recurrent EWSR1::ATF1 fusion and potentially aggressive clinical behavior. Because of its nested...
Objective: Our objectives were to evaluate maternal serum YKL-40 levels in pregnancies complicated by preterm prelabor rupture of membranes (PPROM), compare them with healthy gestational age-comparable controls, and assess the association between YKL...
Hemoptysis is usually attributed to bleeding from bronchial or non-bronchial systemic arterial circulation. Venous airway bleeding is rarely considered, although it requires a different diagnostic and therapeutic approach. A 64-year-old man with a la...
Background/Objectives: Machine learning is increasingly applied to identify hypertension from broad predictor panels, but whether it outperforms a few routine measurements is unclear. We compared machine learning pipelines against three readily obtai...
Background/Objectives: Paediatric pulmonary embolism (PE) is rare but potentially lethal, and its diagnosis is complicated by non-specific presentations and multiple predisposing risk factors. We describe a 15-year-old girl who presented with feature...
Background/Objectives: To achieve effective clinical decision-making from radiographic images, accurate diagnosis of bone fractures is required, but this is difficult due to anatomical variation, subtle fracture appearance, and variable imaging condi...
Background/Objectives: Traumatic intracranial hemorrhage (tICH) in older adults following low-energy falls (LEF) represents a common yet diagnostically challenging condition in the emergency department (ED), where predicting injury prior to computed...
Background/Objectives: We aimed to compare the diagnostic performances of planar bone scintigraphy and whole-body 360° cadmium–zinc–telluride (CZT) bone single-photon emission computed tomography/computed tomography (SPECT/CT) in dete...
Obesity is usually classified or assessed using the body mass index (BMI), mainly because BMI is simple and easy to apply. Its simplicity is also its main weakness. BMI does not measure fat mass, fat-free mass, or fat distribution. This is a relevant...
Background: Neuroendocrine prostate cancer (NEPC) is a rare and aggressive malignancy with limited prognostic tools. The Lung Immune Prognostic Index (LIPI), derived from dNLR and lactate dehydrogenase, has demonstrated prognostic value in small-cell...
Background/Objectives: The role of endoscopic ultrasonography (EUS) in surveillance after endoscopic variceal ligation (EVL) for primary prophylaxis of esophageal variceal hemorrhage remains uncertain. This study compared the predictive value of high...
Background/Objectives: MicroRNAs released into spent culture medium (SCM) may reflect embryo developmental status, but their relationship with blastocyst morphology and time-lapse morphokinetic behavior remains incompletely understood. This prospecti...
The 12-lead electrocardiogram (ECG) is inexpensive, noninvasive, and widely available, but conventional interpretation may not capture subtle signals related to cardiac structure, systemic physiology, and future risk. This review examines the use of...
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