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Pathogenesis and Early Diagnosis of HPV-Related Cancers and Pre-Cancers

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 31

Special Issue Editors


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Guest Editor
Preventive Gynecology Unit, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy
Interests: gynecologic oncology; lower genital tract disease; HPV; colposcopy; ultrasound
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Otorhinolaryngology and Head and Neck Surgery, European Institute of Oncology (IEO), IRCCS, 20141 Milan, Italy
Interests: HPV-related oropharyngeal cancers; head and neck pathology

Special Issue Information

Dear Colleagues,

We are pleased to invite you to contribute to this Special Issue entitled “Pathogenesis and Early Diagnosis of HPV-Related Cancers and Pre-Cancers”. Human papillomavirus (HPV) infection is a well-established cause of several malignancies, including cervical, vaginal, vulvar, anal, penile, and oropharyngeal cancers. Despite major advances in prevention, many questions remain regarding the biological mechanisms underlying the progression from infection to cancer, the identification of individuals at highest risk, and the development of tools to improve early detection.

This Special Issue aims to explore the most recent advances in understanding the pathogenesis of HPV-related cancers and pre-cancers, with a particular focus on early diagnosis. We welcome original research articles and reviews addressing molecular mechanisms, host–virus interactions, and the role of the microbiome, as well as the development and validation of novel molecular assays, biomarkers of persistence or progression, and prognostic indicators of treatment outcomes and recurrence risk.

In this Special Issue, we particularly encourage contributions on translational approaches that may guide clinical practice and improve patient management.

We look forward to hearing from you.

Dr. Anna Daniela Iacobone
Dr. Marta Tagliabue
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • HPV-related cancer
  • molecular diagnostics
  • precancerous lesions
  • biomarkers
  • early detection
  • cervical cancer
  • anal cancer
  • oropharyngeal cancer
  • prognostic factors
  • HPV genotyping

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Published Papers

This special issue is now open for submission.
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