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Diagnostics, Volume 14, Issue 12

2024 June-2 - 107 articles

Cover Story: This study presents the first-ever utilization of anti-RNase aptamers, specifically chosen to target and inactivate RNases in Xtract-Free™, a next-generation sample collection and transport medium. The incorporation of aptamers for RNase inactivation in Xtract-Free™ provides the following advantages: (1) it offers a safe and eco-friendly alternative for both molecular and lateral flow diagnostic tests, eliminating the requirement for nucleic acid extraction prior to PCR, (2) it ensures the preservation and stabilization of RNA for PCR and other RNA-related genomic applications such as RNA-Seq and transcriptome analysis; (3) it broadens the range of collection media beyond traditional viral transport media and caustic molecular transport media, catering to the increasing demand for a safe medium suitable for point-of-care, self-collection, return mail, and home collection purposes. View this paper
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Articles (107)

  • Article
  • Open Access
12 Citations
7,351 Views
13 Pages

Deep Learning-Based Prediction Model for the Cobb Angle in Adolescent Idiopathic Scoliosis Patients

  • Chun-Sing (Elvis) Chui,
  • Zhong He,
  • Tsz-Ping Lam,
  • Ka-Kwan (Kyle) Mak,
  • Hin-Ting (Randy) Ng,
  • Chun-Hai (Ericsson) Fung,
  • Mei-Shuen Chan,
  • Sheung-Wai Law,
  • Yuk-Wai (Wayne) Lee and
  • Shu-Hang (Patrick) Yung
  • + 10 authors

Scoliosis, characterized by spine deformity, is most common in adolescent idiopathic scoliosis (AIS). Manual Cobb angle measurement limitations underscore the need for automated tools. This study employed a vertebral landmark extraction method and Fe...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Article
  • Open Access
8 Citations
2,577 Views
18 Pages

Photon-counting CT systems generally allow for acquiring multiple spectral datasets and thus for decomposing CT images into multiple materials. We introduce a prior knowledge-free deterministic material decomposition approach for quantifying three ma...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
16 Citations
10,459 Views
10 Pages

Hypothyroidism and Heart Rate Variability: Implications for Cardiac Autonomic Regulation

  • Carina Bogdan,
  • Viviana Mihaela Ivan,
  • Adrian Apostol,
  • Oana Elena Sandu,
  • Felix-Mihai Maralescu and
  • Daniel Florin Lighezan

Thyroid hormones have a pivotal role in controlling metabolic processes, cardiovascular function, and autonomic nervous system activity. Hypothyroidism, a prevalent endocrine illness marked by inadequate production of thyroid hormone, has been linked...

(This article belongs to the Special Issue Diagnosis and Prognosis of Heart Disease)
  • Review
  • Open Access
67 Citations
16,444 Views
27 Pages

Advancements in artificial intelligence (AI) are poised to catalyze a transformative shift across diverse dental disciplines including endodontics, oral radiology, orthodontics, pediatric dentistry, periodontology, prosthodontics, and restorative den...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Article
  • Open Access
4 Citations
2,462 Views
12 Pages

Surgical Therapy of Infective Prosthesis Endocarditis following TAVI: A Single Center’s Experience

  • Alexander Weymann,
  • Ali Saad Merzah,
  • Arian Arjomandi Rad,
  • Lukman Amanov,
  • Thanos Athanasiou,
  • Bastian Schmack,
  • Aron-Frederik Popov,
  • Arjang Ruhparwar and
  • Alina Zubarevich

Background/Objectives: Infective prosthesis endocarditis (IE) following transcatheter aortic valve implantation (TAVI) presents significant management challenges, marked by high mortality rates. This study reviews our center’s experience with s...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
2 Citations
7,131 Views
10 Pages

Comparison of Magnetic Resonance Imaging with Electrodiagnosis in the Evaluation of Clinical Suspicion of Lumbosacral Radiculopathy

  • Alberto Montaner-Cuello,
  • Santos Caudevilla-Polo,
  • Diego Rodríguez-Mena,
  • Gianluca Ciuffreda,
  • Pilar Pardos-Aguilella,
  • Isabel Albarova-Corral,
  • Jorge Pérez-Rey and
  • Elena Bueno-Gracia

(1) Background: The diagnosis of lumbosacral radiculopathy involves anamnesis, an assessment of sensitivity and strength, diagnostic imaging—usually magnetic resonance imaging (MRI)—and electrodiagnostic testing (EDX), typically electromy...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
11 Citations
2,958 Views
23 Pages

Currently, brain tumors are extremely harmful and prevalent. Deep learning technologies, including CNNs, UNet, and Transformer, have been applied in brain tumor segmentation for many years and have achieved some success. However, traditional CNNs and...

(This article belongs to the Special Issue Recent Advances in Artificial Intelligence-Based Medical Image Analysis)
  • Article
  • Open Access
1 Citations
1,590 Views
8 Pages

The Role of Vascular Cell Adhesion Molecule-1 (VCAM-1) in Predicting Complicated Appendicitis in Children

  • Wen-Ya Lin,
  • En-Pei Lee,
  • Chun-Yu Chen,
  • Bei-Cyuan Guo,
  • Mao-Jen Lin and
  • Han-Ping Wu

Background: Acute appendicitis is a common abdominal emergency observed in emergency departments (ED). Distinguishing between uncomplicated and complicated appendicitis is important in determining a treatment strategy. Serum soluble vascular cell adh...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Review
  • Open Access
3 Citations
2,038 Views
11 Pages

Homonymous Hemiatrophy of Macular Ganglion Cell Layer as a Marker of Retrograde Neurodegeneration in Multiple Sclerosis—A Narrative Review

  • Larisa Cujbă,
  • Ana Banc,
  • Tudor Drugan,
  • Camelia Alexandra Coadă,
  • Andreea-Petra Cristea,
  • Cristina Stan and
  • Cristina Nicula

Retrograde axonal neurodegeneration along the visual pathway—either direct or trans-synaptic—has already been demonstrated in multiple sclerosis (MS), as well as in compressive, vascular, or posttraumatic lesions of the visual pathway. Op...

(This article belongs to the Special Issue Advanced Role of Optical Coherence Tomography in Clinical Medicine)
  • Case Report
  • Open Access
3 Citations
2,832 Views
10 Pages

Delayed Traumatic Rupture of the Spleen in a Patient with Mantle Cell Non-Hodgkin Lymphoma after an In-Hospital Fall: A Fatal Case

  • Giuseppe Davide Albano,
  • Stefania Zerbo,
  • Mario Spanò,
  • Nello Grassi,
  • Emiliano Maresi,
  • Ada Maria Florena and
  • Antonina Argo

Splenic rupture and hematoma are significant complications that can occur in patients with non-Hodgkin lymphoma (NHL). Understanding these associated complications is essential for optimal patient management and enhanced patient outcomes. Histopathol...

(This article belongs to the Special Issue Updates on Forensic Pathology)
  • Article
  • Open Access
25 Citations
3,761 Views
19 Pages

Google Bard and ChatGPT in Orthopedics: Which Is the Better Doctor in Sports Medicine and Pediatric Orthopedics? The Role of AI in Patient Education

  • Riccardo Giorgino,
  • Mario Alessandri-Bonetti,
  • Matteo Del Re,
  • Fabio Verdoni,
  • Giuseppe M. Peretti and
  • Laura Mangiavini

Background: This study evaluates the potential of ChatGPT and Google Bard as educational tools for patients in orthopedics, focusing on sports medicine and pediatric orthopedics. The aim is to compare the quality of responses provided by these natura...

(This article belongs to the Special Issue Artificial Intelligence in Orthopedic Surgery and Sport Medicine)
  • Interesting Images
  • Open Access
1 Citations
2,961 Views
8 Pages

Twelve-Year Progression of Osteochondral Lesions of the Talus Observed Using Magnetic Resonance Imaging

  • Bradley J. Lauck,
  • Isabel Shaffrey,
  • Albert T. Anastasio,
  • Conor N. O’Neill,
  • Andrew E. Hanselman and
  • Samuel B. Adams

Osteochondral lesions of the talus are common injuries that are most often the result of trauma. The natural progression of osteochondral lesions is not well understood. It is still unclear which lesions eventually lead to joint degeneration and oste...

(This article belongs to the Special Issue Imaging Diagnosis of Foot and Ankle Injuries)
  • Article
  • Open Access
1 Citations
1,975 Views
13 Pages

Hyperspectral Imaging Detects Clitoral Vascular Issues in Gender-Affirming Surgery

  • Torsten Schulz,
  • Hannes Köhler,
  • Lukas Herbert Kohler,
  • Stefan Langer and
  • Rima Nuwayhid

The aim of this study was to assess the efficacy of hyperspectral imaging (HSI) as an intraoperative perfusion imaging modality during gender affirmation surgery (GAS). The hypothesis posited that HSI could quantify perfusion to the clitoral complex,...

(This article belongs to the Section Biomedical Optics)
  • Article
  • Open Access
2 Citations
2,070 Views
12 Pages

The Role of Endoscopic Ultrasonography (EUS) in Metastatic Tumors in the Pancreas: 10 Years of Experience from a Single High-Volume Center

  • Alessandro Aversano,
  • Laura Lissandrini,
  • Daniele Macor,
  • Martina Carbone,
  • Sara Cassarano,
  • Marco Marino,
  • Mauro Giuffrè,
  • Alessandro De Pellegrin,
  • Giovanni Terrosu and
  • Debora Berretti

Background: Metastatic pancreatic lesions (MPLs) are relatively uncommon, constituting 2 to 5% of all pancreatic tumors. They often manifest as solitary lesions without distinct clinical symptoms, usually identified incidentally during radiologic ima...

(This article belongs to the Special Issue Endoscopic Ultrasound (EUS) in Gastrointestinal Diseases)
  • Article
  • Open Access
2 Citations
1,861 Views
14 Pages

Utilizing Aerobic Capacity Data for EDSS Score Estimation in Multiple Sclerosis: A Machine Learning Approach

  • Seda Arslan Tuncer,
  • Cagla Danacı,
  • Furkan Bilek,
  • Caner Feyzi Demir and
  • Taner Tuncer

The Expanded Disability Status Scale (EDSS) is the most popular method to assess disease progression and treatment effectiveness in patients with multiple sclerosis (PwMS). One of the main problems with the EDSS method is that different results can b...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Article
  • Open Access
6 Citations
2,425 Views
14 Pages

Background: Orbital floor fractures (OFFs) represent an interesting chapter in maxillofacial surgery, and one of the main challenges in orbit reconstruction is shaping and cutting the precise contour of the implants due to its complex anatomy. Object...

(This article belongs to the Section Clinical Diagnosis and Prognosis)
  • Systematic Review
  • Open Access
3 Citations
6,641 Views
76 Pages

Objective: This systematic review investigates the diagnostic, prognostic, and therapeutic implications of immunohistochemical markers in dentigerous cysts (DCs) and odontogenic keratocysts (OKCs) associated with impacted third molars. Materials and...

(This article belongs to the Special Issue Advances in the Diagnosis of Oral and Maxillofacial Disease)
  • Review
  • Open Access
10 Citations
4,157 Views
14 Pages

Predictive Factors of Immunotherapy in Gastric Cancer: A 2024 Update

  • Vasile Bintintan,
  • Claudia Burz,
  • Irena Pintea,
  • Adriana Muntean,
  • Diana Deleanu,
  • Iulia Lupan and
  • Gabriel Samasca

Many studies on gastric cancer treatment have identified predictors of immunotherapy benefits. This article provides an update on the major developments in research related to predictive factors of immunotherapy for gastric cancer. We used the search...

(This article belongs to the Special Issue Advances in the Diagnosis of Gastrointestinal Diseases—2nd Edition)
  • Article
  • Open Access
1 Citations
2,140 Views
13 Pages

Prediction Value of Initial Serum Levels of SERPINA3 in Intracranial Pressure and Long-Term Neurological Outcomes in Traumatic Brain Injury

  • Haoyuan Tan,
  • Jiamian Wang,
  • Fengshi Li,
  • Yidong Peng,
  • Jin Lan,
  • Yuanda Zhang,
  • Dongxu Zhao and
  • Yinghui Bao

Traumatic brain injury (TBI) is a severe neurological condition characterized by inflammation in the central nervous system. SERPINA3 has garnered attention as a potential biomarker for assessing this inflammation. Our study aimed to explore the pred...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
5 Citations
2,401 Views
18 Pages

Assessing Lung Fibrosis with ML-Assisted Minimally Invasive OCT Imaging

  • Rebecca Steinberg,
  • Jack Meehan,
  • Doran Tavrow,
  • Gopi Maguluri,
  • John Grimble,
  • Michael Primrose and
  • Nicusor Iftimia

This paper presents a combined optical coherence tomography (OCT) imaging/machine learning (ML) technique for real-time analysis of lung tissue morphology to determine the presence and level of invasiveness of idiopathic lung fibrosis (ILF). This is...

(This article belongs to the Special Issue Optical Coherence Tomography (OCT): State of the Art)
  • Article
  • Open Access
3 Citations
1,979 Views
10 Pages

The Stress Index as a Predictor of Mortality in Patients with Isolated Moderate to Severe Traumatic Brain Injury

  • Ching-Ya Huang,
  • Cheng-Shyuan Rau,
  • Chun-Ying Huang,
  • Wei-Ti Su,
  • Shiun-Yuan Hsu and
  • Ching-Hua Hsieh

Background: The Stress Index (SI), calculated as the ratio of blood glucose to serum potassium levels, is a promising prognostic marker in various acute care settings. This study aimed to evaluate the utility of the SI for predicting mortality in pat...

(This article belongs to the Section Clinical Laboratory Medicine)
  • Article
  • Open Access
2 Citations
3,782 Views
13 Pages

Comparison between the Friedewald, Martin and Sampson Equations and LDL-C Quantification by Ultracentrifugation in a Mexican Population

  • Giovanny Fuentevilla-Álvarez,
  • María Elena Soto,
  • José Antonio García Valdivia,
  • Yazmín Estela Torres-Paz,
  • Reyna Sámano,
  • Israel Perez-Torres,
  • Ricardo Gamboa-Ávila and
  • Claudia Huesca-Gómez

Low-density lipoprotein cholesterol (LDL-C), which makes up about 70% of the cholesterol in the blood, is critical in the formation of arteriosclerotic plaques, increasing the risk of heart disease. LDL-C levels are estimated using Friedewald, Martin...

(This article belongs to the Special Issue Exploring the Role of Diagnostic Biochemistry)
  • Article
  • Open Access
4 Citations
2,062 Views
7 Pages

Backgrounds: Tooth loss in the posterior maxilla often necessitates dental implant placement, but the maxillary sinus anatomy poses challenges, especially during sinus floor elevation. Mesially angled implants are an alternative for total edentulism,...

(This article belongs to the Special Issue New Possibilities for Digital Diagnosis and Planning in Dentistry)
  • Article
  • Open Access
7 Citations
3,269 Views
11 Pages

Gastric Emptying Scintigraphy Protocol Optimization Using Machine Learning for the Detection of Delayed Gastric Emptying

  • Michalis F. Georgiou,
  • Efrosyni Sfakianaki,
  • Monica N. Diaz-Kanelidis and
  • Baha Moshiree

Purpose: The purpose of this study is to examine the feasibility of a machine learning (ML) system for optimizing a gastric emptying scintigraphy (GES) protocol for the detection of delayed gastric emptying (GE), which is considered a primary indicat...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Case Report
  • Open Access
1 Citations
3,285 Views
8 Pages

Rare Superior and Middle Trunk Fusion Accompanied by Altered Division Rearrangement Results in a Unique Brachial Plexus Variant: A Case Report

  • Andreas Marco Schlüter,
  • Konstantin Redl,
  • Thomas Tschernig,
  • Stephan Maxeiner and
  • Gabriela Krasteva-Christ

During routine dissections of cadavers as part of the medical curriculum, we identified a rare unilateral variation in the brachial plexus on the right side of a female body donor. This variation consisted of four unusual changes to the regular patte...

(This article belongs to the Special Issue Advances in Anatomy—Third Edition)
  • Systematic Review
  • Open Access
13 Citations
3,439 Views
12 Pages

Diagnostic Yield of Endoscopic Ultrasound-Guided Liver Biopsy in Comparison to Percutaneous Liver Biopsy: A Meta-Analysis of Randomized Controlled Trials and Trial Sequential Analysis

  • Megha Bhandari,
  • Jayanta Samanta,
  • Marco Spadaccini,
  • Alessandro Fugazza,
  • Stefano Francesco Crinò,
  • Paraskevas Gkolfakis,
  • Konstantinos Triantafyllou,
  • Jahnvi Dhar,
  • Marcello Maida and
  • Antonio Facciorusso
  • + 5 authors

Background: The efficacy of endoscopic ultrasound-guided liver biopsy (EUS-LB) compared to percutaneous liver biopsy (PC-LB) remains uncertain. Methods: Our data consist of randomized controlled trials (RCTs) comparing EUS-LB to PC-LB, found through...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
12 Citations
3,109 Views
12 Pages

Application of Quantitative Ultrasonography and Artificial Intelligence for Assessing Severity of Fatty Liver: A Pilot Study

  • Hyuksool Kwon,
  • Myeong-Gee Kim,
  • SeokHwan Oh,
  • Youngmin Kim,
  • Guil Jung,
  • Hyeon-Jik Lee,
  • Sang-Yun Kim and
  • Hyeon-Min Bae

Non-alcoholic fatty liver disease (NAFLD), prevalent among conditions like obesity and diabetes, is globally significant. Existing ultrasound diagnosis methods, despite their use, often lack accuracy and precision, necessitating innovative solutions...

(This article belongs to the Special Issue The Role of AI in Ultrasound)
  • Article
  • Open Access
1 Citations
2,078 Views
16 Pages

A Combination of Amide Proton Transfer, Tumor Blood Flow, and Apparent Diffusion Coefficient Histogram Analysis Is Useful for Differentiating Malignant from Benign Intracranial Tumors in Young Patients: A Preliminary Study

  • Fumine Tanaka,
  • Masayuki Maeda,
  • Ryohei Nakayama,
  • Katsuhiro Inoue,
  • Seiya Kishi,
  • Ryota Kogue,
  • Maki Umino,
  • Yotaro Kitano,
  • Makoto Obara and
  • Hajime Sakuma

Purpose: To evaluate the amide proton transfer (APT), tumor blood flow (TBF), and apparent diffusion coefficient (ADC) combined diagnostic value for differentiating intracranial malignant tumors (MTs) from benign tumors (BTs) in young patients, as de...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Correction
  • Open Access
1 Citations
1,306 Views
2 Pages

Correction: Nistor et al. Primary Cardiac Intimal Sarcoma: Multi-Layered Strategy and Core Role of MDM2 Amplification/Co-Amplification and MDM2 Immunostaining. Diagnostics 2024, 14, 919

  • Claudiu Nistor,
  • Camelia Stanciu Gavan,
  • Adelina Birceanu,
  • Cezar Betianu,
  • Mara Carsote,
  • Anca-Pati Cucu,
  • Mihaela Stanciu,
  • Florina Ligia Popa,
  • Adrian Ciuche and
  • Mihai-Lucian Ciobica

Camelia Stanciu Gavan, Adelina Birceanu, and Cezar Betianu were not included as authors in the original publication [...]

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
8 Citations
4,462 Views
20 Pages

Cholesterol Gallstones and Long-Term Use of Statins: Is Gut Microbiota Dysbiosis Bridging over Uncertainties?

  • Doina Georgescu,
  • Daniel-Florin Lighezan,
  • Ioana Ionita,
  • Nicoleta Hadaruga,
  • Roxana Buzas,
  • Ciprian-Ilie Rosca,
  • Mihai Ionita,
  • Ioana Suceava,
  • Diana-Alexandra Mitu and
  • Oana-Elena Ancusa

A total of 300 research participants—200 consecutive patients diagnosed with dyslipidemia (100 statin (+), treated for at least five years, and 100 statin (−)) and 100 healthy controls—were included in this observational study. The...

(This article belongs to the Section Diagnostic Microbiology and Infectious Disease)
  • Review
  • Open Access
4 Citations
5,309 Views
19 Pages

The Role of Endoscopic Ultrasound and Ancillary Techniques in the Diagnosis of Autoimmune Pancreatitis: A Comprehensive Review

  • Flavio Metelli,
  • Guido Manfredi,
  • Nico Pagano,
  • Elisabetta Buscarini,
  • Stefano Francesco Crinò and
  • Elia Armellini

Autoimmune pancreatitis (AIP) is a unique form of chronic pancreatitis with a multifactorial pathogenesis. Historically, it has been classified as type 1 and type 2, according to its clinical and histological features. The diagnosis of AIP is challen...

(This article belongs to the Special Issue Endoscopic Ultrasound (EUS) in Gastrointestinal Diseases)
  • Article
  • Open Access
1 Citations
5,250 Views
12 Pages

Eustachian tube dysfunction (ETD) affects a significant portion of the population, manifesting symptoms that impact the quality of life. Despite the prevalence of ETD, there remains a notable gap in comprehensive studies exploring the condition&rsquo...

(This article belongs to the Special Issue Diagnosis and Management in Otolaryngology 2026)
  • Communication
  • Open Access
1 Citations
3,040 Views
12 Pages

High-Resolution Magnetic Resonance Neurography at 7T: A Pilot Study of Hand Innervation

  • Pauline C. Guillemin,
  • David Ferreira Branco,
  • Yacine M’Rad,
  • Loan Mattera,
  • Orane Lorton,
  • Gian Franco Piredda,
  • Antoine Klauser,
  • Roberto Martuzzi,
  • Pierre-Alexandre Poletti and
  • Sana Boudabbous
  • + 1 author

The emergence of 7T clinical MRI technology has sparked our interest in its ability to discern the complex structures of the hand. Our primary objective was to assess the sensory and motor nerve structures of the hand, specifically nerves and Pacinia...

(This article belongs to the Special Issue Clinical Advances and Applications in Neuroradiology)
  • Article
  • Open Access
8 Citations
2,826 Views
14 Pages

This study evaluates the efficacy of several Convolutional Neural Network (CNN) models for the classification of hearing loss in patients using preprocessed auditory brainstem response (ABR) image data. Specifically, we employed six CNN architectures...

(This article belongs to the Special Issue Deep Learning Techniques for Medical Image Analysis)
  • Article
  • Open Access
3 Citations
6,941 Views
11 Pages

Evaluation of Pre-Transfusion Crossmatch Test Using Microscanner C3

  • Insu Park,
  • Woong Sik Jang,
  • Chae Seung Lim and
  • Jeeyong Kim

A pre-transfusion crossmatch test is crucial for ensuring safe blood transfusions by identifying the compatibility between donor and recipient blood samples. Conventional tube methods for crossmatching have limitations, including subjectivity in resu...

(This article belongs to the Special Issue A Useful Diagnostic Method: Blood Test)
  • Article
  • Open Access
3 Citations
2,344 Views
11 Pages

Hypovitaminosis D and Leukocytosis to Predict Cardiovascular Abnormalities in Children with Kawasaki Disease: Insights from a Single-Center Retrospective Observational Cohort Study

  • Donato Rigante,
  • Gabriella De Rosa,
  • Angelica Bibiana Delogu,
  • Giulia Rotunno,
  • Rossella Cianci,
  • Claudia Di Pangrazio,
  • Giorgio Sodero,
  • Umberto Basile and
  • Marcello Candelli

Introduction: An aberrant immune response involving yet unidentified environmental and genetic factors plays a crucial role in triggering Kawasaki disease (KD). Aims: The aim of this study was to assess general and laboratory data at the onset of KD...

(This article belongs to the Special Issue Cardiovascular Diseases: Diagnosis and Management)
  • Case Report
  • Open Access
5,776 Views
6 Pages

Objective: Neck pain is commonly referred to an ENT specialist and can be caused by the little-known inflammatory condition of the lateral thyrohyoid ligament. The pathophysiology of this condition is believed to be inflammation subsequent to over-ex...

(This article belongs to the Special Issue Clinical Diagnosis of Otorhinolaryngology)
  • Article
  • Open Access
2 Citations
2,849 Views
10 Pages

Diffusion Tensor Imaging Identifies Cervical Spondylosis, Myelitis, and Spinal Cord Tumors

  • Jiyuan Wang,
  • Jing Huang,
  • Bixiao Cui,
  • Hongwei Yang,
  • Defeng Tian,
  • Jie Ma,
  • Wanru Duan,
  • Huiqing Dong,
  • Zan Chen and
  • Jie Lu

Background: Diffusion tensor imaging (DTI) has been increasingly recognized for its capability to study microstructural changes in the neuropathology of brain diseases. However, the optimal DTI metric and its diagnostic utility for a variety of spina...

(This article belongs to the Special Issue Recent Advances in Radiomics in Medical Imaging)
  • Article
  • Open Access
2 Citations
2,768 Views
16 Pages

This study aimed to characterize the Magnetic Resonance Imaging (MRI) features of the Anterolateral Ligament (ALL) in young adults without Anterior Cruciate Ligament (ACL) injury and evaluate its visibility using MRI. In this retrospective analysis,...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
2 Citations
2,603 Views
11 Pages

High-Frequency Vestibular Function Is Vulnerable to Presbyvestibulopathy

  • Seonghoon Bae,
  • Jimin Yun,
  • Seungmin Kwak,
  • Hyuntaek Jung,
  • Hancheol Lee,
  • Juyoung Kim,
  • Chanhee Kim,
  • Yujin Lee and
  • Sunghuhn Kim

Introduction: In 2019, mild vestibular function deficiency in elder populations was defined as presbyvestibulopathy (PVP) by the Classification Committee of the Bárány Society. The diagnostic criteria include tests for low-, mid-, and h...

(This article belongs to the Special Issue Advances in Diagnosis and Treatment in Otolaryngology)
  • Review
  • Open Access
13 Citations
6,502 Views
15 Pages

Dual-Energy and Photon-Counting Computed Tomography in Vascular Applications—Technical Background and Post-Processing Techniques

  • Marcin Stański,
  • Ilona Michałowska,
  • Adam Lemanowicz,
  • Katarzyna Karmelita-Katulska,
  • Przemysław Ratajczak,
  • Agata Sławińska and
  • Zbigniew Serafin

The field of computed tomography (CT), which is a basic diagnostic tool in clinical practice, has recently undergone rapid technological advances. These include the evolution of dual-energy CT (DECT) and development of photon-counting computed tomogr...

(This article belongs to the Special Issue Computed Tomography Imaging in Medical Diagnosis)
  • Article
  • Open Access
8 Citations
4,626 Views
13 Pages

Incidence of Carotid Blowout Syndrome in Patients with Head and Neck Cancer after Radiation Therapy: A Cohort Study

  • Jian-Lin Jiang,
  • Joseph Tung-Chieh Chang,
  • Chih-Hua Yeh,
  • Ting-Yu Chang,
  • Bing-Shen Huang,
  • Pi-Shan Sung,
  • Chien-Yu Lin,
  • Kang-Hsing Fan,
  • Yi-Chia Wei and
  • Chi-Hung Liu

Carotid blowout syndrome (CBS) is a rare yet life-threatening complication that occurs after radiation therapy (RT). This study aimed to determine the incidence of CBS in patients with head and neck cancer (HNC) undergoing contemporary RT and to expl...

(This article belongs to the Special Issue Clinical Diagnosis of Otorhinolaryngology)
  • Article
  • Open Access
4 Citations
2,127 Views
15 Pages

Optical coherence tomography (OCT) is a non-invasive imaging technique based on the principle of low-coherence interferometry that captures detailed images of ocular structures. Multiple sclerosis (MS) is a neurodegenerative disease that can lead to...

(This article belongs to the Special Issue Advanced Role of Optical Coherence Tomography in Clinical Medicine)
  • Article
  • Open Access
5,012 Views
11 Pages

Establishing Quality Assurance for HIV-1 Rapid Test for Recent Infection in Thailand through the Utilization of Dried Tube Specimens

  • Supaporn Suparak,
  • Petai Unpol,
  • Kanokwan Ngueanchanthong,
  • Sirilada Pimpa Chisholm,
  • Siriphailin Jomjunyoung,
  • Wipawee Thanyacharern,
  • Nitis Smanthong,
  • Pojaporn Pinrod,
  • Kriengkrai Srithanaviboonchai and
  • Sanny Northbrook
  • + 4 authors

The present study focuses on establishing the quality assurance of laboratories for recent infections (RTRI) in Thailand. We developed a cold-chain independent method, using fully characterized plasma obtained from the Thai Red Cross Society, and pre...

(This article belongs to the Special Issue 21st Century Point-of-Care, Near-Patient and Critical Care Testing)
  • Article
  • Open Access
1 Citations
3,614 Views
15 Pages

Changes of Dissociative Properties of Hemoglobin in Patients with Chronic Kidney Disease

  • Justyna Korus,
  • Maria Wydro,
  • Maciej Gołębiowski,
  • Kornelia Krakowska,
  • Paweł Poznański,
  • Kinga Musiał,
  • Andrzej Konieczny,
  • Hanna Augustyniak-Bartosik,
  • Jakub Stojanowski and
  • Tomasz Gołębiowski
  • + 1 author

Background: The ability of hemoglobin to bind and dissociate oxygen is crucial in delivering oxygen to tissues and is influenced by a range of physiological states, compensatory mechanisms, and pathological conditions. This may be illustrated by the...

(This article belongs to the Special Issue Advances in Diagnostics of Chronic Kidney Disease)
  • Review
  • Open Access
4 Citations
2,153 Views
18 Pages

Elastography of the Male Pelvic Region—Perspectives on Malignant Lesions

  • Rute Santos,
  • Martina Kastrup Loft and
  • Malene Roland Vils Pedersen

Ultrasound elastography is widely used to assess tissue stiffness for lesion characterization, including differentiation between benign and malignant lesions. This study focuses on the use of elastography in the male pelvis, including the prostate, t...

(This article belongs to the Special Issue Current Perspectives and Advances in Ultrasound Imaging)
  • Article
  • Open Access
19 Citations
5,160 Views
17 Pages

Segmentation and Multi-Timepoint Tracking of 3D Cancer Organoids from Optical Coherence Tomography Images Using Deep Neural Networks

  • Francesco Branciforti,
  • Massimo Salvi,
  • Filippo D’Agostino,
  • Francesco Marzola,
  • Sara Cornacchia,
  • Maria Olimpia De Titta,
  • Girolamo Mastronuzzi,
  • Isotta Meloni,
  • Miriam Moschetta and
  • Kristen M. Meiburger
  • + 13 authors

Recent years have ushered in a transformative era in in vitro modeling with the advent of organoids, three-dimensional structures derived from stem cells or patient tumor cells. Still, fully harnessing the potential of organoids requires advanced ima...

(This article belongs to the Special Issue Optical Coherence Tomography (OCT): State of the Art)
  • Article
  • Open Access
6 Citations
2,228 Views
15 Pages

Use of Deep-Amplicon Sequencing (DAS), Real-Time PCR and In Situ Hybridization to Detect H. pylori and Other Pathogenic Helicobacter Species in Feces from Children

  • Yolanda Moreno Trigos,
  • Miguel Tortajada-Girbés,
  • Raquel Simó-Jordá,
  • Manuel Hernández Pérez,
  • Irene Hortelano,
  • Miguel García-Ferrús and
  • María Antonia Ferrús Pérez

Background: Detecting Helicobacter pylori in fecal samples is easier and more comfortable than invasive techniques, especially in children. Thus, the objective of the present work was to detect H. pylori in feces from children by molecular methods as...

(This article belongs to the Section Diagnostic Microbiology and Infectious Disease)
  • Article
  • Open Access
3 Citations
4,619 Views
13 Pages

Magnetic Resonance Imaging Features of Plantar Vein Thrombosis

  • Frederico Celestino Miranda,
  • Adham do Amaral e Castro,
  • Ariadne Moura Obrigon,
  • Alexandre Leme Godoy-Santos,
  • Durval do Carmo Barros Santos,
  • Laercio Alberto Rosemberg and
  • Atul Kumar Taneja

Plantar vein thrombosis (PVT) is an underdiagnosed condition affecting the deep plantar veins, with challenging clinical diagnosis, often presenting with non-specific symptoms that mimic other foot pathologies. This study assessed the magnetic resona...

(This article belongs to the Special Issue Advances in Foot and Ankle Surgery: Diagnosis and Management)
  • Review
  • Open Access
14 Citations
8,207 Views
17 Pages

Diagnostic Role of Multi-Detector Computed Tomography in Acute Mesenteric Ischemia

  • Francesco Michele Ronza,
  • Teresa Letizia Di Gennaro,
  • Gianfranco Buzzo,
  • Luciana Piccolo,
  • Marina Della Noce,
  • Giovanni Giordano,
  • Giuseppe Posillico,
  • Luigi Pietrobono,
  • Francesco Giuseppe Mazzei and
  • Stefania Tamburrini
  • + 3 authors

Mesenteric ischemia diagnosis is challenging, with an overall mortality of up to 50% of cases despite advances in treatment. The main problem that affects the outcome is delayed diagnosis because of non-specific clinical presentation. Multi-Detector...

(This article belongs to the Special Issue Imaging Diagnosis in Abdomen, 2nd Edition)

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Diagnostics - ISSN 2075-4418