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Diagnostics, Volume 11, Issue 8

August 2021 - 217 articles

Cover Story: Medical laboratories have evolved massively over the past few decades. However, focusing mainly on intra-laboratory processes, laboratories slowly degenerated into a sole supplier of test results. It is time that laboratory specialists start providing their vast expertise in test selection and interpretation in order to contribute to optimal patient care. As the amount of data which need to be processed exceeds human capacity, the aid of artificial intelligence systems is inevitably needed. However, care needs to be taken with regard to their risks, benefits, requirements, and limitations. View this paper
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Articles (217)

  • Article
  • Open Access
15 Citations
4,015 Views
11 Pages

Shortening the Time of the Identification and Antimicrobial Susceptibility Testing on Positive Blood Cultures with MALDI-TOF MS

  • Ya-Wen Tsai,
  • Ting-Chia Lin,
  • Hsiu-Yin Chou,
  • Huei-Ya Hung,
  • Che-Kim Tan,
  • Li-Ching Wu,
  • I-Jung Feng and
  • Yow-Ling Shiue

The current processes used in clinical microbiology laboratories take ~24 h for incubation to identify the bacteria after the blood culture has been confirmed as positive and fa further ~24 h to report the results of antimicrobial susceptibility test...

  • Article
  • Open Access
8 Citations
3,084 Views
13 Pages

Stability of OCT and OCTA in the Intensive Therapy Unit Setting

  • Ella F. Courtie,
  • Aditya U. Kale,
  • Benjamin T. K. Hui,
  • Xiaoxuan Liu,
  • Nicholas I. Capewell,
  • Jonathan R. B. Bishop,
  • Tony Whitehouse,
  • Tonny Veenith,
  • Ann Logan and
  • Alastair K. Denniston
  • + 1 author

To assess the stability of retinal structure and blood flow measures over time and in different clinical settings using portable optical coherence tomography angiography (OCTA) as a potential biomarker of central perfusion in critical illness, 18 oes...

  • Article
  • Open Access
13 Citations
4,534 Views
14 Pages

Observation of Chronic Graft-Versus-Host Disease Mouse Model Cornea with In Vivo Confocal Microscopy

  • Shota Shimizu,
  • Shinri Sato,
  • Hiroko Taniguchi,
  • Eisuke Shimizu,
  • Jingliang He,
  • Shunsuke Hayashi,
  • Kazuno Negishi,
  • Yoko Ogawa and
  • Shigeto Shimmura

Graft-versus-host disease (GVHD) is a major complication after hematopoietic stem cell transplantation (HSCT), and ocular GVHD can cause severe dry eye disease that can lead to visual impairment. Epithelial damage, vascular invasion, corneal fibrosis...

  • Review
  • Open Access
25 Citations
7,042 Views
29 Pages

Framing Cause-Effect Relationship of Acute Coronary Syndrome in Patients with Chronic Kidney Disease

  • Mădălina Ioana Moisi,
  • Simona Gabriela Bungau,
  • Cosmin Mihai Vesa,
  • Camelia Cristina Diaconu,
  • Tapan Behl,
  • Manuela Stoicescu,
  • Mirela Mărioara Toma,
  • Cristiana Bustea,
  • Cristian Sava and
  • Mircea Ioachim Popescu

The main causes of death in patients with chronic kidney disease (CKD) are of cardiovascular nature. The interaction between traditional cardiovascular risk factors (CVRF) and non-traditional risk factors (RF) triggers various complex pathophysiologi...

  • Article
  • Open Access
13 Citations
3,033 Views
13 Pages

Prediction Model for Tumor Budding Status Using the Radiomic Features of F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Cervical Cancer

  • Gun Oh Chong,
  • Shin-Hyung Park,
  • Shin Young Jeong,
  • Su Jeong Kim,
  • Nora Jee-Young Park,
  • Yoon Hee Lee,
  • Sang-Woo Lee,
  • Dae Gy Hong,
  • Ji Young Park and
  • Hyung Soo Han

Objective: To compare the radiomic features of F-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and intratumoral heterogeneity according to tumor budding (TB) status and to develop a prediction model for the T...

  • Case Report
  • Open Access
7 Citations
4,376 Views
8 Pages

Focal Myocarditis after Mild COVID-19 Infection in Athletes

  • Ivana P. Nedeljkovic,
  • Vojislav Giga,
  • Marina Ostojic,
  • Ana Djordjevic-Dikic,
  • Tamara Stojmenovic,
  • Ivan Nikolic,
  • Nenad Dikic,
  • Olga Nedeljkovic-Arsenovic,
  • Ruzica Maksimovic and
  • Milan Dobric
  • + 2 authors

COVID-19 infection in athletes usually has a milder course, but in the case of complications, myocarditis and even sudden cardiac death may occur. We examined an athlete who felt symptoms upon returning to training after asymptomatic COVID-19 infecti...

  • Article
  • Open Access
9 Citations
3,335 Views
9 Pages

Visualization of Forward Light Scatter in Opacified Intraocular Lenses and Straylight Assessment

  • Hyeck-Soo Son,
  • Grzegorz Łabuz,
  • Ramin Khoramnia,
  • Timur M. Yildirim,
  • Chul Young Choi,
  • Michael C. Knorz and
  • Gerd U. Auffarth

Background: Qualitative visualization of forward light scatter and quantitative straylight measurement of intraocular lenses (IOLs). Methods: We analyzed two calcified IOL-explants, the Euromaxx ALI313Y (Argonoptics GmbH) and the LS-312 MF30 (Oculent...

  • Article
  • Open Access
7 Citations
3,297 Views
10 Pages

Mouth Washing Impaired SARS-CoV-2 Detection in Saliva

  • Monique Melo Costa,
  • Nicolas Benoit,
  • Hervé Tissot-Dupont,
  • Matthieu Million,
  • Bruno Pradines,
  • Samuel Granjeaud and
  • Lionel Almeras

Background: A previous study demonstrated the performance of the Salivette® (SARSTEDT, Numbrecht, Germany) as a homogeneous saliva collection system to diagnose COVID-19 by RT-qPCR, notably for symptomatic and asymptomatic patients. However, for conv...

  • Article
  • Open Access
3 Citations
3,338 Views
17 Pages

IVUS Longitudinal and Axial Registration for Atherosclerosis Progression Evaluation

  • Nikos Tsiknakis,
  • Constantinos Spanakis,
  • Panagiota Tsompou,
  • Georgia Karanasiou,
  • Gianna Karanasiou,
  • Antonis Sakellarios,
  • George Rigas,
  • Savvas Kyriakidis,
  • Michael Papafaklis and
  • Sotirios Nikopoulos
  • + 4 authors

Intravascular ultrasound (IVUS) imaging offers accurate cross-sectional vessel information. To this end, registering temporal IVUS pullbacks acquired at two time points can assist the clinicians to accurately assess pathophysiological changes in the...

  • Article
  • Open Access
14 Citations
5,005 Views
12 Pages

Watch and Wait Approach for Rectal Cancer Following Neoadjuvant Treatment: The Experience of a High Volume Cancer Center

  • Daniela Rega,
  • Vincenza Granata,
  • Carmela Romano,
  • Valentina D’Angelo,
  • Ugo Pace,
  • Roberta Fusco,
  • Carmela Cervone,
  • Vincenzo Ravo,
  • Fabiana Tatangelo and
  • Antonio Avallone
  • + 2 authors

Multimodal treatments for rectal cancer, along with significant research on predictors to response to therapy, have led to more conservative surgical strategies. We describe our experience of the rectal sparing approach in rectal cancer patients with...

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Diagnostics - ISSN 2075-4418