Polymers, Volume 14, Issue 5
2022 March-1 - 221 articles
Cover Story: Biodegradable and biomimetic delivery platforms able to transport and protect active agents are currently considered strategic for a successful bone tissue regeneration. The present investigation developed degradable poly(lactic-co-glycolic)acid (PLGA) nanocarriers suitable for the release of transforming growth factor-beta 1 (TGF-β1) and their further combination with type-I-collagen to create a 3D-printable hybrid formulation. The resulting nanostructured 3D-printed scaffolds successfully mimicked TGF-β1 presence in human bone extracellular matrix as assessed by immunohistochemistry. Moreover, the incorporation of the polymeric carriers into the collagenous matrix enabled a sustained release kinetics of the biomolecule. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
- You may sign up for email alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.