Table of Contents
Crystals, Volume 10, Issue 10 (October 2020) – 104 articles
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Cover Story (view full-size image) Nanolipoprotein particles (NLPs), also called “nanodiscs”, are discoidal lipid bilayer patches [...] Read more. Nanolipoprotein particles (NLPs), also called “nanodiscs”, are discoidal lipid bilayer patches corralled by apolipoproteins into which membrane proteins can be inserted and solubilized. To (1) facilitate future understanding of the role of two apolipoprotein/lipid complexes, ApoA1 and ApoE4, in lipid binding, and (2) develop new methods for serial femtosecond crystallography (SFX) with X-ray free electron lasers involving NLP membrane protein solubilization, we have prepared and crystallized ApoA1 and ApoE4 NLPs and implemented a fast-scanning fixed target sample delivery scheme utilizing ultra-thin polymer/graphene support films, providing a low sample volume, low-background approach to membrane protein SFX. These represent initial steps in developing these membrane mimetics as supporting scaffolds for future structural studies of membrane proteins crystalized in a native lipid environment. View this paper