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Open AccessFeature PaperArticle

Integration of Horizontal and Vertical Microfluidic Modules for Core-Shell Droplet Generation and Chemical Application

1
Research Organization for Nano & Life Innovation, Waseda University, 513, Tsurumaki-cho, Waseda, Shinjuku-ku, Tokyo 162-0041, Japan
2
Faculty of Science and Engineering, Waseda University, 3-4-1, Okubo, Shinjuku-ku, Tokyo 169-8555, Japan
*
Author to whom correspondence should be addressed.
Micromachines 2019, 10(9), 613; https://doi.org/10.3390/mi10090613
Received: 17 August 2019 / Revised: 13 September 2019 / Accepted: 13 September 2019 / Published: 15 September 2019
This paper presents a method for utilizing three-dimensional microfluidic channels fully to realize multiple functions in a single device. The final device structure was achieved by combining three independent modules that consisted of horizontal and vertical channels. The device allowed for the one-step generation of water-in-oil-in-water droplets without the need for partial treatment of the polydimethylsiloxane channel surface using separate modules for generating water-in-oil droplets on the horizontal plane and oil-in-water droplets on the vertical plane. The second vertically structured module provided an efficient flow for the generation of highly wettable liquid droplets, and tuning of the first horizontally structured module enabled different modes of inner-core encapsulation within the oil shell. The successful integration of the vertical and horizontal channels for core-shell droplet generation and the chemical synthesis of a metal complex within the droplets were evaluated. The proposed approach of integrating independent modules will expand and enhance the functions of microfluidic platforms. View Full-Text
Keywords: three-dimensional structure; device integration; microdroplet; double emulsion three-dimensional structure; device integration; microdroplet; double emulsion
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MDPI and ACS Style

Yoon, D.H.; Nozaki, Y.; Tanaka, D.; Sekiguchi, T.; Shoji, S. Integration of Horizontal and Vertical Microfluidic Modules for Core-Shell Droplet Generation and Chemical Application. Micromachines 2019, 10, 613.

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