Table of Contents
Viruses, Volume 10, Issue 10 (October 2018)
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Cover Story (view full-size image) Photodynamic inactivation (PDI) employs a photosensitizer, light, and oxygen to create a local [...] Read more. Photodynamic inactivation (PDI) employs a photosensitizer, light, and oxygen to create a local burst of reactive oxygen species that inactivate microorganisms. Here, we report the PDI of herpes simplex viruses by the botanical plant extract OrthoquinTM in a dose-dependent manner across a broad range of sub-cytotoxic concentrations. Orthoquin also inhibited adenovirus infection in a light-dependent manner, whereas vesicular stomatitis viruses were inhibited in a light-independent manner. View this paper.