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Special Issue "Biotechnological Applications of Phage and Phage-Derived Proteins"
Deadline for manuscript submissions: closed (30 April 2018).
Bacteriophages, the viruses of bacteria, are recognized for their potential as antimicrobial agents since their discovery, roughly a century ago, but the early inadequately controlled trials, the poor knowledge on their biology and the discovery of antibiotics has slowed phage research. In recent years, the increasing problem of multidrug-resistant bacteria has renewed and heightened interest in the use of phages as antimicrobial agents.
The recent progress in sequencing technologies, DNA manipulation and synthetic biology has equipped scientists with the necessary tools to disclose and use the powerful armamentarium of proteins that phages possess to parasite bacteria. These proteins can be used ex-phage (isolated from the phage particle) or modified/added to design phages with improved and superior characteristics and functionalities which enabled the development of new powerful applications of phages and their proteins not only in therapeutics (as new source of antimicrobials, drug delivery systems and vaccines) but also in diagnostics and materials science (for the assembly of new materials). As new phage proteins are being discovered, new valuable biotechnological applications are envisaged.
With the wide array of possibilities offered by genetic engineering and its attracting intense interest coupled with the high potential of phages, this Special Issue will focus on new biotechnological applications of phage and their derived proteins, as well on the new strategies to obtain them. Bacteriophage therapy through the use of wild type phages (without any genetic modification) is out of focus of this special issue.
Dr. Sílvio Santos
Prof. Dr. Joana Azeredo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- biotechnological applications
- genetic engineering