Viruses, Volume 10, Issue 9 (September 2018) – 66 articles
Cover Story (view full-size image): CRISPR-Cas systems provide adaptive immunity in bacteria and capture invasive DNA sequences to create a genetic record of vaccination events. These loci enable the reconstruction of the interplay between microbes and their viral invaders. Deep sequencing data capture this CRISPR-encoded molecular interplay in various microbiomes from diverse niches encompassing oceans, soil, plant, animals, humans, and more. This framework presents new opportunities to understand and manipulate microbial communities for enhanced therapeutic or biocontrol functionalities. View this paper.
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