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Molecules, Volume 24, Issue 22

November-2 2019 - 190 articles

Cover Story: Chelating bisphosphonate dendrons fitted with oligo(ethylene glycol) chains and terminated by a fluorinated moiety can anchor iron oxide nanoparticles in the phospholipid shells of microbubbles and respond to the presence of a fluorocarbon gas. Here we investigate the miscibility of these dendrons with phospholipids in Langmuir monolayers, as a model interface of microbubble shells. We demonstrate that the dendrons are squeezed out of the mixed monolayers during compression. This suggests that these dendrons can be specifically designed to facilitate the in vivo delivery of magnetic nanoparticles, allowing for the combined use of ultrasound and magnetic resonance for, in particular, tumor imaging. View this paper.
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Articles (190)

  • Article
  • Open Access
12 Citations
3,258 Views
13 Pages

19 November 2019

A diatomite supported graphene oxide composite (GO@Dt–NH2) was fabricated and explored as a solid-phase extraction adsorbent coupled with high performance liquid chromatography to determine the trace hydroxyl polycyclic aromatic hydrocarbons (2...

  • Review
  • Open Access
23 Citations
9,687 Views
34 Pages

19 November 2019

Nicotinamide adenine dinucleotide (NAD) serves as an essential redox co-factor and mediator of multiple biological processes. Besides its well-established role in electron transfer reactions, NAD serves as a substrate for other biotransformations, wh...

  • Review
  • Open Access
34 Citations
6,347 Views
16 Pages

19 November 2019

Fibrosis is a type of chronic organ failure, resulting in the excessive secretion of extracellular matrix (ECM). ECM protects wound tissue from infection and additional injury, and is gradually degraded during wound healing. For some unknown reasons,...

  • Review
  • Open Access
36 Citations
5,691 Views
16 Pages

DNA-Templated Fluorescent Nanoclusters for Metal Ions Detection

  • Chunxia Song,
  • Jingyuan Xu,
  • Ying Chen,
  • Liangliang Zhang,
  • Ying Lu and
  • Zhihe Qing

19 November 2019

DNA-templated fluorescent nanoclusters (NCs) have attracted increasing research interest on account of their prominent features, such as DNA sequence-dependent fluorescence, easy functionalization, wide availability, water solubility, and excellent b...

  • Review
  • Open Access
43 Citations
13,294 Views
35 Pages

A Survey of Molecular Imaging of Opioid Receptors

  • Paul Cumming,
  • János Marton,
  • Tuomas O. Lilius,
  • Dag Erlend Olberg and
  • Axel Rominger

19 November 2019

The discovery of endogenous peptide ligands for morphine binding sites occurred in parallel with the identification of three subclasses of opioid receptor (OR), traditionally designated as μ, δ, and κ, along with the more recently defi...

  • Article
  • Open Access
23 Citations
3,438 Views
11 Pages

Synthesis and Antiproliferative Evaluation of Novel Hybrids of Dehydroabietic Acid Bearing 1,2,3-Triazole Moiety

  • Fang-Yao Li,
  • Lin Huang,
  • Qian Li,
  • Xiu Wang,
  • Xian-Li Ma,
  • Cai-Na Jiang,
  • Xiao-Qun Zhou,
  • Wen-Gui Duan and
  • Fu-Hou Lei

19 November 2019

To discover novel potent cytotoxic diterpenoids, a series of hybrids of dehydroabietic acid containing 1,2,3-triazole moiety were designed and synthesized. The target compounds were characterized by means of FT-IR, 1H NMR, 13C NMR, ESI-MS and element...

  • Feature Paper
  • Review
  • Open Access
95 Citations
17,848 Views
18 Pages

19 November 2019

Ectonucleotide pyrophosphatase/phosphodiesterase I (ENPP1) was identified several decades ago as a type II transmembrane glycoprotein with nucleotide pyrophosphatase and phosphodiesterase enzymatic activities, critical for purinergic signaling. Recen...

  • Article
  • Open Access
15 Citations
4,391 Views
15 Pages

19 November 2019

Amomi Fructus is one of the traditional medicines derived from the ripe fruits of the Zingiberaceae family of plants, which include Amomum villosum, A. villosum var. xanthioides, and A. longiligulare. Owing to their highly similar morphological trait...

  • Article
  • Open Access
58 Citations
4,708 Views
20 Pages

19 November 2019

Environmental pollution is the most serious problem that affects crop productivity worldwide. Pisum sativum is a leguminous plant that is cultivated on a large scale in the Nile Delta of Egypt as a winter crop, and many of the cultivated fields irrig...

  • Article
  • Open Access
3 Citations
3,999 Views
18 Pages

19 November 2019

The hydrolysis–condensation reactions of m-tolyl, m-chlorophenyl, and α-naphtyl-trichlorsilanes, (1, 2, and 3, respectively) in water-acetone solutions were examined for how they were influenced by the change in the concentration of HCl (...

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Molecules - ISSN 1420-3049