Synthesis and Application of Quinolines and Quinoline Derivatives

Dear Colleagues,

Quinoline moiety is one of the most often recognized fragments in bioactive compounds. Soon after it was first isolated, quinoline was identified in various pharmaceutically important alkaloids, like quinine and cinchonine. In addition to this, synthetic procedures were developed, further increasing research. Since then, thousands of scientific papers have been published on this topic. Today, the knowledge gathered in last 180 years is the basis for more rational design novel substances and materials. Quinoline derivatives are known for their exceptionally broad spectrum of activity, including antimicrobial, antiviral and anticancer potency. Among literally each class of the most important small molecule drugs, a quinoline ring can be noticed. Several derivatives were also exploited as dyes, molecular sensors or intelligent materials. Undoubtedly, the good synthetic availability of wide range structural derivatives and manipulation of their electronic properties is the reason for this popularity of quinoline fragment. Thus, in this current Special Issue, original research papers and reviews on every aspect of synthesis and application of quinoline derivatives will be considered. Short communications on the hot topics of this field of ever growing knowledge are also warmly welcomed.

Prof. Dr. Robert Musioł
Guest Editor

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