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Molecules, Volume 24, Issue 21

November-1 2019 - 200 articles

Cover Story: A new pH sensor based on a substituted aroylhydrazide with a flexible side chain and a terminal trimethyl ammonium group (PHA+) was designed and synthesized. The charged chain guarantees excellent solubility in water. The probe is also very soluble in hydrophobic environments and acts as a pH-sensitive fluorophore/chromophore probe. DFT calculations, single-crystal X-ray data, and molecular dynamics simulations were related to the optical behavior. Changes in the fluorescence color with a strong on–off switch effect at neutral pH have been detected, both in solution and in the solid state. The high Stoke shift, the ability to interact with membranes, the sharp response to pH changes, and the solvatochromism make PHA+ the starting point to develop a new generation of biosensors. View this paper.
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Articles (200)

  • Article
  • Open Access
8 Citations
3,705 Views
17 Pages

5 November 2019

Carbon fiber mesh reinforced cement-based composites (CMCCs) have received extensive attention in the field of engineering repair and structural reinforcement due to their outstanding properties such as two-way force, rust prevention, high specific s...

  • Article
  • Open Access
3 Citations
3,409 Views
15 Pages

5 November 2019

Multi-component formulations offer a way to modulate the physico-chemical properties of drug molecules and thereby enhance their efficacy as medicines compared to using only the raw drug, with mechano-chemical synthesis being an increasingly popular...

  • Article
  • Open Access
16 Citations
4,795 Views
15 Pages

Anti-Bacterial Effect and Cytotoxicity Assessment of Lipid 430 Isolated from Algibacter sp.

  • Yannik K.-H. Schneider,
  • Kine Ø. Hansen,
  • Johan Isaksson,
  • Sara Ullsten,
  • Espen H. Hansen and
  • Jeanette Hammer Andersen

5 November 2019

Two bacterial isolates from the Barents Sea, both belonging to the genus Algibacter, were found to yield extracts with anti-bacterial bioactivity. Mass spectrometry guided dereplication and purification of the active extracts lead to the isolation of...

  • Feature Paper
  • Review
  • Open Access
64 Citations
11,793 Views
19 Pages

5 November 2019

Cardiovascular functionality strictly depends on endothelial cell trophism and proper biochemical function. Any condition (environmental, pharmacological/toxicological, physical, or neuro-humoral) that changes the vascular endothelium has great conse...

  • Article
  • Open Access
16 Citations
4,210 Views
22 Pages

5 November 2019

Administration of subanesthetic doses of ketamine during brain maturation represents a tool to mimic an early insult to the central nervous system (CNS). The cerebellum is a key player in psychosis pathogenesis, to which oxidative stress also contrib...

  • Article
  • Open Access
9 Citations
3,917 Views
14 Pages

Lasianosides A–E: New Iridoid Glucosides from the Leaves of Lasianthus verticillatus (Lour.) Merr. and Their Antioxidant Activity

  • Gadah Abdulaziz Al-Hamoud,
  • Raha Saud Orfali,
  • Shagufta Perveen,
  • Kenta Mizuno,
  • Yoshio Takeda,
  • Tatsuo Nehira,
  • Kazuma Masuda,
  • Sachiko Sugimoto,
  • Yoshi Yamano and
  • Hideaki Otsuka
  • + 1 author

5 November 2019

The genus Lasianthus (Rubiaceae) consists of approximately 180 species, of which the greatest species diversity is found in tropical Asia. Some of the Lasianthus species have been used in folk medicine to treat tinnitus, arthritis, fever, and bleedin...

  • Article
  • Open Access
12 Citations
3,535 Views
10 Pages

5 November 2019

Glycosyltransferase-producing Leuconostoc lactis CCK940 produces CCK- oligosaccharides, gluco-oligosaccharide molecules, using sucrose and maltose as donor and acceptor molecules, respectively. In this study, the immunostimulatory activities of CCK-o...

  • Feature Paper
  • Article
  • Open Access
7 Citations
3,773 Views
13 Pages

Magnetic Behavior of Carbon Materials Made from Biomass by Fe-Assisted Hydrothermal Carbonization

  • Mara Olivares,
  • Silvia Román,
  • Beatriz Ledesma and
  • Alfredo Álvarez

5 November 2019

Biomass magnetic materials were synthesized by several hydrothermal carbonization methods, by which iron was provided in different ways: as FeCl3 prior to or during hydrothermal carbonization, as pure Fe particles, or as magnetic ferrofluid, followed...

  • Article
  • Open Access
21 Citations
3,715 Views
14 Pages

Evaluation of the Strain Bacillus amyloliquefaciens YP6 in Phoxim Degradation via Transcriptomic Data and Product Analysis

  • Di Meng,
  • Liyuan Zhang,
  • Jie Meng,
  • Qiaopeng Tian,
  • Lixin Zhai,
  • Zhikui Hao,
  • Zhengbing Guan,
  • Yujie Cai and
  • Xiangru Liao

5 November 2019

Phoxim, a type of organophosphorus pesticide (OP), is widely used in both agriculture and fisheries. The persistence of phoxim has caused serious environmental pollution problems. In this study, Bacillus amyloliquefaciens YP6 (YP6), which is capable...

  • Article
  • Open Access
19 Citations
4,454 Views
11 Pages

Structural Analysis of Gluco-Oligosaccharides Produced by Leuconostoc lactis and Their Prebiotic Effect

  • Sulhee Lee,
  • Jisun Park,
  • Jae-Kweon Jang,
  • Byung-Hoo Lee and
  • Young-Seo Park

5 November 2019

Leuconostoc lactis CCK940, which exhibits glycosyltransferase activity, produces oligosaccharides using sucrose and maltose as donor and receptor molecules, respectively. The oligosaccharides produced were purified by Bio-gel P2 chromatography and th...

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Molecules - ISSN 1420-3049