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42 Results Found

  • Article
  • Open Access
2 Citations
856 Views
12 Pages

Efficient Implementation of a Robot-Assisted Radical Cystectomy Program in a Naïve Centre Experienced in Open Radical Cystectomy and Other Robot-Assisted Surgeries: A Comparative Analysis of Perioperative Outcomes and Complications

  • Gianluca Giannarini,
  • Gioacchino De Giorgi,
  • Maria Abbinante,
  • Carmine Franzese,
  • Jeanlou Collavino,
  • Fabio Traunero,
  • Marco Buttazzi,
  • Antonio Amodeo,
  • Angelo Porreca and
  • Alessandro Crestani

31 July 2025

Background/Objectives: While robot-assisted radical cystectomy (RARC) has shown potential benefits over open radical cystectomy (ORC), such as reduced blood loss and quicker recovery, its adoption has been limited because of its complexity and long l...

  • Article
  • Open Access
1 Citations
2,334 Views
10 Pages

29 January 2024

Background: Bladder cancer is a common urinary tract malignancy. Minimally invasive radical cystectomy has shown oncological outcomes comparable to the conventional open surgery and with advantages over the open procedure. However, outcomes of the tw...

  • Article
  • Open Access
20 Citations
2,148 Views
10 Pages

Assessing Trifecta and Pentafecta Success Rates between Robot-Assisted vs. Open Radical Cystectomy: A Propensity Score-Matched Analysis

  • Filippo Gavi,
  • Nazario Foschi,
  • Daniele Fettucciari,
  • Pierluigi Russo,
  • Diana Giannarelli,
  • Mauro Ragonese,
  • Carlo Gandi,
  • Giovanni Balocchi,
  • Alessandra Francocci and
  • Emilio Sacco
  • + 7 authors

25 March 2024

Background: This study aimed to evaluate the surgical and oncological outcomes of robot-assisted radical cystectomy (RARC) versus open radical cystectomy (ORC) using trifecta and pentafecta parameters. Methods: The clinical data of 41 patients who un...

  • Article
  • Open Access
1 Citations
1,963 Views
11 Pages

Pre-Op Hydronephrosis Predicts Outcomes in Patients Receiving Robot-Assisted Radical Cystectomy

  • Chris Ho-Ming Wong,
  • Ivan Ching-Ho Ko,
  • David Ka-Wai Leung,
  • Seok Ho Kang,
  • Kousuke Kitamura,
  • Shigeo Horie,
  • Satoru Muto,
  • Chikara Ohyama,
  • Shingo Hatakeyama and
  • Eddie Chan
  • + 9 authors

12 August 2024

Introduction: Robot-assisted radical cystectomy (RARC) has gained momentum in the management of muscle invasive bladder cancer (MIBC). Predictors of RARC outcomes are not thoroughly studied. We aim to investigate the implications of preoperative hydr...

  • Article
  • Open Access
3 Citations
2,844 Views
11 Pages

Open versus Robot-Assisted Radical Cystectomy for the Treatment of pT4a Bladder Cancer: Comparison of Perioperative Outcomes

  • Davide Perri,
  • Bernardo Rocco,
  • Maria Chiara Sighinolfi,
  • Pierluigi Bove,
  • Antonio L. Pastore,
  • Alessandro Volpe,
  • Andrea Minervini,
  • Alessandro Antonelli,
  • Stefano Zaramella and
  • Giorgio Bozzini
  • + 13 authors

28 March 2024

We compared the perioperative outcomes of open (ORC) vs. robot-assisted (RARC) radical cystectomy in the treatment of pT4a MIBC. In total, 212 patients underwent ORC (102 patients, Group A) vs. RARC (110 patients, Group B) for pT4a bladder cancer. Pa...

  • Article
  • Open Access
4 Citations
2,526 Views
11 Pages

Efficacy and Safety of the “Trisection Method” Training System for Robot-Assisted Radical Cystectomy at a Single Institution in Japan

  • Keita Nakane,
  • Toyohiro Yamada,
  • Risa Tomioka-Inagawa,
  • Fumiya Sugino,
  • Naotaka Kumada,
  • Makoto Kawase,
  • Shinichi Takeuchi,
  • Kota Kawase,
  • Daiki Kato and
  • Takuya Koie
  • + 2 authors

29 November 2022

To maintain a surgeon’s concentration, reduce fatigue, and train young surgeons, surgical procedures for bladder cancer are divided into the following parts: robot-assisted radical cystectomy (RARC), bowel reconstruction, and totally intracorpo...

  • Article
  • Open Access
4 Citations
3,651 Views
17 Pages

Robot-Assisted Radical Cystectomy with Modified Vesica Ileale Padovana (VIP) Neobladder Configuration Using a Hybrid Approach: Initial Experience

  • Fumitaka Shimizu,
  • Satoru Muto,
  • Kosuke Kitamura,
  • Toshiyuki China,
  • Tomoya Shirakawa,
  • Tomoki Kimura,
  • Takeshi Ieda,
  • Masayoshi Nagata,
  • Shuji Isotani and
  • Shigeo Horie
  • + 1 author

Purpose: We developed a new technique to fold a neobladder (NB) simply by using a modified Vesica Ileale Padovana (VIP) with a hybrid approach. We provide a step-by-step description of our technique as it was used in this initial experience. Methods:...

  • Article
  • Open Access
888 Views
12 Pages

Evolution of Perioperative Outcomes in Robot-Assisted Radical Cystectomy over 20 Years of Experience in a High-Volume Tertiary Robotic Center

  • Simone Morra,
  • Stefano Resca,
  • Nicola Frego,
  • Sara Tamburini,
  • Marco Ticonosco,
  • Alessandro Pissavini,
  • Andrea Noya Mourullo,
  • Francesco Barletta,
  • Mario de Angelis and
  • Alexandre Mottrie
  • + 4 authors

19 September 2025

Background/Objectives: Robot-assisted radical cystectomy (RARC) has demonstrated improved perioperative outcomes and recovery in bladder cancer (BCa) patients. This study compares patient and tumor characteristics, operative time (OT), length of stay...

  • Review
  • Open Access
19 Citations
4,085 Views
9 Pages

13 October 2021

Benign ureteroenteric anastomosis strictures (UESs) are one of many critical complications that may cause irreversible disability following robot-assisted radical cystectomy (RARC). Previous studies have shown that the incidence rates of UES after RA...

  • Systematic Review
  • Open Access
3 Citations
2,867 Views
16 Pages

Learning Curves in Robotic Urological Oncological Surgery: Has Anything Changed During the Last Five Years?

  • Theodoros Tokas,
  • Charalampos Mavridis,
  • Athanasios Bouchalakis,
  • Chrisoula Maria Nakou and
  • Charalampos Mamoulakis

15 April 2025

Background: Despite numerous studies assessing LCs in urological surgical oncology, high-quality evidence and a fully structured curriculum are missing. We aimed to systematically search and review the available literature on the LCs of robot-assiste...

  • Article
  • Open Access
1 Citations
1,155 Views
14 Pages

Robot-Assisted Radical Cystectomy with Ureterocutaneostomy: A Potentially Optimal Solution for Octogenarian and Frail Patients with Bladder Cancer

  • Angelo Porreca,
  • Filippo Marino,
  • Davide De Marchi,
  • Alessandro Crestani,
  • Daniele D’Agostino,
  • Paolo Corsi,
  • Francesca Simonetti,
  • Susy Dal Bello,
  • Gian Maria Busetto and
  • Luca Di Gianfrancesco
  • + 10 authors

10 July 2025

Background/Objectives: Robot-assisted radical cystectomy (RARC) has become the primary approach for treating bladder cancer, replacing the traditional open procedure. The robotic approach, when combined with ureterocutaneostomy (UCS), offers signific...

  • Article
  • Open Access
3 Citations
2,640 Views
11 Pages

Robot-Assisted Radical Cystectomy: A Single-Center Experience and a Narrative Review of Recent Evidence

  • Bernardo Rocco,
  • Giulia Garelli,
  • Simone Assumma,
  • Filippo Turri,
  • Mattia Sangalli,
  • Tommaso Calcagnile,
  • Giorgia Gaia,
  • Stefano Terzoni,
  • Guglielmo Oliviero and
  • Maria Chiara Sighinolfi
  • + 7 authors

14 February 2023

Radical cystectomy represents one of the most challenging surgical procedures, exhibiting a high morbidity rate. The transition to minimally invasive surgery in the field has been steep, due to either the technical complexity and prior concerns of at...

  • Article
  • Open Access
1 Citations
1,010 Views
12 Pages

Estimating the Morbidity of Robot-Assisted Radical Cystectomy Using the Comprehensive Complication Index: Data from the Asian Robot-Assisted Radical Cystectomy Consortium

  • Alvin Lee Yuanming,
  • Fiona Tan Bei Na,
  • Raj Tiwari,
  • Thomas Kong Ngai Chan,
  • Jeremy Yuen-Chun Teoh,
  • Seok-Ho Kang,
  • Manish I. Patel,
  • Satoru Muto,
  • Cheng-Kuang Yang and
  • Lui-Shiong Lee
  • + 6 authors

29 March 2025

Background/Objectives: The Clavien–Dindo classification (CDC) grades the most severe post-operative complication and may not comprehensively reflect cumulative surgical morbidity. Our objective was to investigate the potential incremental role...

  • Article
  • Open Access
8 Citations
3,690 Views
12 Pages

Association between Ureteral Clamping Time and Acute Kidney Injury during Robot-Assisted Radical Cystectomy

  • Yudai Ishiyama,
  • Tsunenori Kondo,
  • Hiroki Ishihara,
  • Kazuhiko Yoshida,
  • Junpei Iizuka,
  • Kazunari Tanabe and
  • Toshio Takagi

29 November 2021

Robot-assisted radical cystectomy (RARC) is replacing open radical cystectomy (ORC) and requires clamping of the ureters, resulting in a predisposition to postrenal acute kidney injury (AKI). We investigated the association between ureteral clamping...

  • Article
  • Open Access
3 Citations
1,609 Views
13 Pages

Retrospective Evaluation of a Single Surgeon’s Learning Curve of Robot-Assisted Radical Cystectomy with Intracorporeal Urinary Diversion via Ileal Conduit

  • Christof Achermann,
  • Andreas Sauer,
  • Marco Cattaneo,
  • Jochen Walz,
  • Stephen F. Wyler,
  • Maciej Kwiatkowski and
  • Lukas W. Prause

26 July 2023

Robot-assisted radical cystectomy with intracorporeal urinary diversion (iRARC) is increasingly being performed instead of open surgery. A criticism of this technique is the long learning curve, but limited data are available on this topic. At our ce...

  • Article
  • Open Access
3 Citations
1,809 Views
10 Pages

Comparing Robotic-Assisted to Open Radical Cystectomy in the Management of Non-Muscle-Invasive Bladder Cancer: A Propensity Score Matched-Pair Analysis

  • Etienne Courboin,
  • Romain Mathieu,
  • Valentina Panetta,
  • Georges Mjaess,
  • Romain Diamand,
  • Gregory Verhoest,
  • Mathieu Roumiguié,
  • Anne Sophie Bajeot,
  • Francesco Soria and
  • Simone Albisinni
  • + 21 authors

26 September 2023

Background: For non-muscle-invasive bladder cancer (NMIBC) requiring radical surgery, limited data are available comparing robotic-assisted radical cystectomy with intracorporeal urinary diversion (iRARC) to open radical cystectomy (ORC). The objecti...

  • Article
  • Open Access
2 Citations
1,401 Views
11 Pages

The Role of Robotic Cystectomy in the Salvage and Palliative Setting: A Retrospective, Single-Center, Cohort Study

  • Aldo Brassetti,
  • Loris Cacciatore,
  • Flavia Proietti,
  • Rigoberto Pallares-Méndez,
  • Alfredo Maria Bove,
  • Umberto Anceschi,
  • Riccardo Mastroianni,
  • Leonardo Misuraca,
  • Gabriele Tuderti and
  • Giuseppe Simone
  • + 4 authors

10 November 2024

Introduction: This article compares surgical and survival outcomes of robot-assisted and open radical cystectomy with cutaneous ureterostomy for the treatment of frail bladder cancer patients with limited life expectancy. Methods: The institutional d...

  • Article
  • Open Access
1,956 Views
10 Pages

Impact of the Enhanced Recovery After Surgery Protocol on the Perioperative Outcomes of Robot-Assisted Radical Cystectomy

  • Kosuke Kitamura,
  • Yuto Miyoshi,
  • Takeshi Ieda,
  • Toshiyuki China,
  • Fumitaka Shimizu,
  • Shigeo Horie and
  • Satoru Muto

29 April 2025

Objectives: The enhanced recovery after surgery (ERAS) protocol is a coordinated approach aimed at providing the best evidence-based perioperative care. This study examined whether combining robot-assisted radical cystectomy (RARC) with the ERAS prot...

  • Article
  • Open Access
7 Citations
2,208 Views
11 Pages

Impacts of Neoadjuvant Chemotherapy on Perioperative Outcomes in Patients with Bladder Cancer Treated with Radical Cystectomy: A Single High-Volume Center Experience

  • Flavia Proietti,
  • Rocco Simone Flammia,
  • Leslie Claire Licari,
  • Eugenio Bologna,
  • Alfredo Maria Bove,
  • Aldo Brassetti,
  • Gabriele Tuderti,
  • Riccardo Mastroianni,
  • Antonio Tufano and
  • Costantino Leonardo
  • + 1 author

16 February 2024

(1) Background: Less than 30% of patients with muscle-invasive bladder cancer (MIBC) receive neoadjuvant chemotherapy (NAC), and reasons for underuse remain unclear. One potential explanation is the concern for the increased risk of perioperative mor...

  • Review
  • Open Access
4 Citations
2,347 Views
14 Pages

Sexual-Sparing Radical Cystectomy in the Robot-Assisted Era: A Review on Functional and Oncological Outcomes

  • Carlo Introini,
  • Manfredi Bruno Sequi,
  • Marco Ennas,
  • Andrea Benelli,
  • Giovanni Guano,
  • Antonio Luigi Pastore and
  • Antonio Carbone

1 January 2025

Background/Objectives: Radical cystectomy (RC) is the standard treatment for muscle-invasive and high-risk non-muscle-invasive bladder cancer, but it often results in significant functional impairments, including sexual and urinary dysfunction, adver...

  • Article
  • Open Access
1 Citations
1,199 Views
15 Pages

Contemporary Trends and Predictors Associated with Adverse Pathological Upstaging Among Non-Metastatic Localized Clinical T2 Muscle-Invasive Bladder Cancers Undergoing Radical Cystectomy: Outcomes from a Single Tertiary Centre in the United Kingdom

  • Francesco Del Giudice,
  • Yasmin Abu-Ghanem,
  • Rajesh Nair,
  • Elsie Mensah,
  • Jonathan Kam,
  • Youssef Ibrahim,
  • Mohamed Gad,
  • Kathryn Chatterton,
  • Suzanne Amery and
  • Muhammad Shamim Khan
  • + 10 authors

27 April 2025

Introduction: Radical cystectomy (RC) is the gold standard for urothelial cT2-4a, N0, M0 muscle-invasive bladder cancer (MIBC). However, bladder-sparing strategies (BSS) such as Trimodality Therapy (TMT) have emerged as alternative treatments for a s...

  • Article
  • Open Access
34 Citations
4,037 Views
10 Pages

Sex-Sparing Robot-Assisted Radical Cystectomy with Intracorporeal Padua Ileal Neobladder in Female: Surgical Technique, Perioperative, Oncologic and Functional Outcomes

  • Gabriele Tuderti,
  • Riccardo Mastroianni,
  • Simone Flammia,
  • Mariaconsiglia Ferriero,
  • Costantino Leonardo,
  • Umberto Anceschi,
  • Aldo Brassetti,
  • Salvatore Guaglianone,
  • Michele Gallucci and
  • Giuseppe Simone

20 February 2020

Our aim was to illustrate our technique of sex-sparing (SS)-robot-assisted radical cystectomy (RARC) in female patients receiving an intracorporeal neobladder (iN). From January 2013 to June 2018, 11 female patients underwent SS-RARC-iN at a single t...

  • Systematic Review
  • Open Access
10 Citations
3,406 Views
14 Pages

Comparative Outcomes of Open Radical Cystectomy vs. Robot-Assisted Approaches with Intracorporeal and Extracorporeal Urinary Diversion: A Meta-Analysis and Network Meta-Analysis of Perioperative and Quality of Life Outcomes

  • Rocco Simone Flammia,
  • Leslie Claire Licari,
  • Eugenio Bologna,
  • Riccardo Mastroianni,
  • Flavia Proietti,
  • Gabriele Tuderti,
  • Umberto Anceschi,
  • Aldo Brassetti,
  • Antonio Franco and
  • Giuseppe Simone
  • + 3 authors

21 April 2024

Background: To conduct a comprehensive systematic review and network meta-analysis of RCTs that compare outcomes of robot-assisted radical cystectomy (RARC) with intra- or extracorporeal urinary diversion (ICUD or ECUD) and the standard open approach...

  • Article
  • Open Access
15 Citations
3,992 Views
11 Pages

Open Versus Robotic Cystectomy: A Propensity Score Matched Analysis Comparing Survival Outcomes

  • Marco Moschini,
  • Stefania Zamboni,
  • Francesco Soria,
  • Romain Mathieu,
  • Evanguelos Xylinas,
  • Wei Shen Tan,
  • John D Kelly,
  • Giuseppe Simone,
  • Anoop Meraney and
  • Shahrokh F. Shariat
  • + 22 authors

9 August 2019

Background: To assess the differential effect of robotic assisted radical cystectomy (RARC) versus open radical cystectomy (ORC) on survival outcomes in matched analyses performed on a large multicentric cohort. Methods: The study included 9757 patie...

  • Review
  • Open Access
3 Citations
1,959 Views
17 Pages

Single-Port vs. Multi-Port Robotic Surgery in Urologic Oncology: A Comparative Analysis of Current Evidence and Future Directions

  • Stamatios Katsimperis,
  • Lazaros Tzelves,
  • Georgios Feretzakis,
  • Themistoklis Bellos,
  • Konstantinos Douroumis,
  • Nikolaos Kostakopoulos and
  • Andreas Skolarikos

29 August 2025

The evolution of robotic surgery in urologic oncology has led to the emergence of single-port (SP) robotic systems as a potential alternative to the widely adopted multi-port (MP) platforms. This narrative review provides a comprehensive comparison b...

  • Article
  • Open Access
2,216 Views
11 Pages

Robotic-Assisted Radical Cystectomy: Single-Center Analysis of Factors Impacting Clavien ≥ II Complications

  • Maria Chiara Sighinolfi,
  • Tommaso Calcagnile,
  • Enrico Panio,
  • Simone Assumma,
  • Luca Sarchi,
  • Marco Sandri,
  • Emanuela Santangelo,
  • Michele Petix,
  • Mattia Sangalli and
  • Bernardo Rocco
  • + 4 authors

31 August 2024

Despite the advent of robotics and the decreasing rate of complications after radical cystectomy, several factors are renowned to impair the early outcomes of this procedure. The aim of this paper is to provide a multivariate analysis (MVA) of patien...

  • Article
  • Open Access
21 Citations
3,567 Views
10 Pages

Recovery from Anesthesia after Robotic-Assisted Radical Cystectomy: Two Different Reversals of Neuromuscular Blockade

  • Claudia Claroni,
  • Marco Covotta,
  • Giulia Torregiani,
  • Maria Elena Marcelli,
  • Gabriele Tuderti,
  • Giuseppe Simone,
  • Alessandra Scotto di Uccio,
  • Antonio Zinilli and
  • Ester Forastiere

24 October 2019

During robot-assisted radical cystectomy (RARC), specific surgical conditions (a steep Trendelenburg position, prolonged pneumoperitoneum, effective myoresolution until the final stages of surgery) can seriously impair the outcomes. The aim of the st...

  • Review
  • Open Access
9 Citations
6,667 Views
17 Pages

Neobladder “Function”: Tips and Tricks for Surgery and Postoperative Management

  • Daniela Fasanella,
  • Michele Marchioni,
  • Luigi Domanico,
  • Claudia Franzini,
  • Antonino Inferrera,
  • Luigi Schips and
  • Francesco Greco

4 August 2022

Orthotopic neobladder (ONB) reconstruction is a continent urinary diversion procedure increasingly used in patients with muscle-invasive bladder cancer following radical cystectomy (RC). It represents a valid alternative to the ileal duct in suitable...

  • Article
  • Open Access
12 Citations
2,348 Views
10 Pages

Impact of Clinical Response to Neoadjuvant Chemotherapy in the Era of Robot Assisted Radical Cystectomy: Results of a Single-Center Experience

  • Umberto Anceschi,
  • Aldo Brassetti,
  • Gabriele Tuderti,
  • Maria Consiglia Ferriero,
  • Manuela Costantini,
  • Alfredo Maria Bove,
  • Fabio Calabrò,
  • Paolo Carlini,
  • Sabrina Vari and
  • Giuseppe Simone
  • + 2 authors

24 August 2020

Background: Response to neoadjuvant chemotherapy (NACT) has been proven to be an established prognostic factor after open radical cystectomy (ORC). We evaluated the impact of NACT on survival outcomes of a single-institution robotic radical cystectom...

  • Feature Paper
  • Review
  • Open Access
1 Citations
3,733 Views
12 Pages

Robotics in Urology: No More Shadows?

  • Lorenzo Giuseppe Luciani,
  • Daniele Mattevi,
  • Tommaso Cai and
  • Gianni Malossini

2 December 2021

Robotic surgery saw unprecedented success throughout the world, with urology as a key discipline. Robotic-assisted radical prostatectomy (RARP) and partial nephrectomy (RAPN) were the frontline procedures. Many other urologic procedures have since be...

  • Article
  • Open Access
8 Citations
2,906 Views
11 Pages

Robot-Assisted Intracorporeal Orthotopic Ileal Neobladder: Description of the “Shell” Technique

  • Roberto Bianchi,
  • Francesco Alessandro Mistretta,
  • Gennaro Musi,
  • Stefano Luzzago,
  • Michele Morelli,
  • Vito Lorusso,
  • Michele Catellani,
  • Ettore Di Trapani,
  • Gabriele Cozzi and
  • Ottavio de Cobelli
  • + 3 authors

16 August 2021

Background: Robot-assisted radical cystectomy (RARC) with intracorporeal neobladder (ICNB) remains a very complicated, technically demanding and time-consuming surgical procedure. In the current study we describe our robot-assisted intracorporeal “Sh...

  • Article
  • Open Access
2 Citations
1,987 Views
11 Pages

Intra-Diverticular Bladder Tumours: How to Manage Rationally

  • Mohammed Lotfi Amer,
  • Hassan Mumtaz,
  • Beth Russell,
  • Jason Gan,
  • Zahra Rehman,
  • Rajesh Nair,
  • Ramesh Thurairaja and
  • Muhammad Shamim Khan

16 September 2022

Objective: To report changing practice in the management of intra-diverticular bladder tumours. Methods: We undertook a review of all intra-diverticular bladder tumours in our prospectively maintained institutional database. Results: A total of 28 pa...

  • Article
  • Open Access
2 Citations
2,252 Views
11 Pages

31 August 2022

Enhanced recovery protocols and robotic approaches to radical cystectomy are known to reduce perioperative complications; however, the most cost-effective strategy is unknown. We aim to assess the cost effectiveness of radical cystectomy with differe...

  • Case Report
  • Open Access
1 Citations
2,825 Views
8 Pages

29 December 2021

Uretero-enteric anastomotic strictures (UES) after robot-assisted radical cystectomy (RARC) represent the main cause of post-operative renal dysfunction. The gold standard for treatment of UES is open uretero-ileal reimplantation (UIR), which is ofte...

  • Article
  • Open Access
324 Views
11 Pages

How to Minimize Hyper-Continence After Intracorporeal Robotic Neobladder Configuration in Women? The Three-Layer Posterior Reconstruction During Florence Robotic IntraCorporeal Neobladder (FloRIN)

  • Fabrizio Di Maida,
  • Luca Lambertini,
  • Antonio Andrea Grosso,
  • Vincenzo Salamone,
  • Daniele Paganelli,
  • Laura Di Stefano,
  • Francesca Conte,
  • Filippo Lipparini,
  • Matteo Salvi and
  • Andrea Minervini
  • + 2 authors

26 November 2025

Background: Orthotopic neobladder in women presents functional challenges, notably hyper-continence requiring intermittent self-catheterization. Here, we describe a three-layer urethro-ileal anastomosis incorporating a peritoneal flap and evaluate it...

  • Article
  • Open Access
1 Citations
2,348 Views
13 Pages

The Feasibility and Diagnostic Adequacy of PD-L1 Expression Analysis Using the Cytoinclusion Technique in Bladder Cancer: A Prospective Single-Center Study

  • Luca Di Gianfrancesco,
  • Isabella Monia Montagner,
  • Debora Tormen,
  • Alessandro Crestani,
  • Antonio Amodeo,
  • Paolo Corsi,
  • Davide De Marchi,
  • Eugenio Miglioranza,
  • Giuliana Lista and
  • Angelo Porreca
  • + 5 authors

12 July 2024

Background: Programmed death-ligand 1 (PD-L1) expression has been recognized as a potential biomarker for various cancers, yet its diagnostic and prognostic significance in urothelial bladder cancer (BCa) requires further investigation. Methods: In t...

  • Systematic Review
  • Open Access
3 Citations
998 Views
16 Pages

Female Sexual Function After Radical Treatment for MIBC: A Systematic Review

  • Francesco Pio Bizzarri,
  • Marco Campetella,
  • Salvatore Marco Recupero,
  • Fabrizio Bellavia,
  • Lorenzo D’Amico,
  • Francesco Rossi,
  • Filippo Gavi,
  • Giovanni Battista Filomena,
  • Pierluigi Russo and
  • Bernardo Rocco
  • + 7 authors

2 September 2025

Background: Sexuality in women with muscle-invasive bladder cancer (MIBC) undergoing radical treatment represents a crucial aspect of their overall quality of life, which is increasingly recognized as a key component of patient-centered care and long...

  • Article
  • Open Access
859 Views
13 Pages

Clinical Predictors and Prognostic Significance of Pathologic Disease Upstaging at Radical Cystectomy in Patients with Muscle-Invasive Bladder Cancer

  • Salvador Jaime-Casas,
  • Wesley Yip,
  • Daniel J. Lama,
  • Vitor Goes,
  • Miguel Zugman,
  • Koral Shah,
  • Regina Barragan-Carrillo,
  • Hedyeh Ebrahimi,
  • Daniela V. Castro and
  • Abhishek Tripathi
  • + 9 authors

9 October 2025

Introduction: Staging inaccuracies in muscle-invasive bladder cancer (MIBC) can lead to undertreatment or overtreatment. We evaluated clinical and pathological predictors of pathologic upstaging (pUS) stratifying by neoadjuvant chemotherapy (NAC) rec...

  • Article
  • Open Access
109 Views
13 Pages

Unveiling the Female Factor: Gender-Based Differences in Outcomes and Survival Following Radical Cystectomy for Bladder Cancer

  • Federico Ceria,
  • Gad Muhammad,
  • Francesco Del Giudice,
  • Youssef Ibrahim,
  • Ramesh Thurairaja,
  • Rajesh Nair,
  • Elsie Mensah,
  • Muhammad Shamim Khan and
  • Yasmin Abu Ghanem

20 January 2026

Background: Female patients undergoing radical cystectomy (RC) for bladder cancer have historically presented with more advanced disease and poorer survival outcomes than males. These disparities have been attributed to biological differences, delaye...

  • Article
  • Open Access
14 Citations
3,003 Views
10 Pages

Benchmarking PASADENA Consensus along the Learning Curve of Robotic Radical Cystectomy with Intracorporeal Neobladder: CUSUM Based Assessment

  • Riccardo Lombardo,
  • Riccardo Mastroianni,
  • Gabriele Tuderti,
  • Mariaconsiglia Ferriero,
  • Aldo Brassetti,
  • Umberto Anceschi,
  • Salvatore Guaglianone,
  • Cosimo De Nunzio,
  • Antonio Cicione and
  • Giuseppe Simone
  • + 2 authors

19 December 2021

(1) Aim: Robot assisted radical cystectomy (RARC) with intacorporeal neobladder (iN) is a challenging procedure. There is a paucity of reports on RARC-iN, the extracorporeal approach being the most used. The aim of our study was to assess the learnin...

  • Review
  • Open Access
4,313 Views
18 Pages

Nerve at Risk: A Narrative Review of Surgical Nerve Injuries in Urological Practice

  • Gaia Colalillo,
  • Simona Ippoliti,
  • Vincenzo M. Altieri,
  • Pietro Saldutto,
  • Riccardo Galli and
  • Anastasios D. Asimakopoulos

Background: Iatrogenic nerve injuries (NIs) are an under-recognized complication of urological surgery. Though less common than vascular or organ damage, they may cause lasting sensory and motor deficits, significantly affecting patients’ quali...

  • Article
  • Open Access
1 Citations
959 Views
13 Pages

Delayed vs. Concomitant Urethrectomy for Non-Metastatic Urothelial Carcinoma of the Urinary Bladder Undergoing Radical Cystectomy: Perioperative and Survival Outcomes from a Single Tertiary Centre in the United Kingdom

  • Francesco Del Giudice,
  • Mohamed Gad,
  • Valerio Santarelli,
  • Rajesh Nair,
  • Yasmin Abu-Ghanem,
  • Elsie Mensah,
  • Ben Challacombe,
  • Jonathan Kam,
  • Youssef Ibrahim and
  • Muhammad Shamim Khan
  • + 14 authors

14 August 2025

Introduction: The role of urethrectomy at the time of Robotic-Assisted or Open Radical Cystectomy (RARC, ORC) is controversial. Whether urethrectomy should be performed at the time of RARC/ORC or delayed up to a 3–6 month interval is unclear. W...