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12 Results Found

  • Article
  • Open Access
2 Citations
4,022 Views
21 Pages

Differences and Similarities in the Feet of Metatarsalgia Patients with and without Rheumatoid Arthritis in Remission

  • Rebeca Bueno Fermoso,
  • Maria Rosario Morales Lozano,
  • Marta Nieto Cordero,
  • Carmen Martínez Rincón,
  • Pablo García-Fernández and
  • María Luz González Fernández

14 May 2024

Objectives: Metatarsalgia continues to be a problem in patients with rheumatoid arthritis (RA) in remission (remRA), as well as in the non-rheumatic population, with a mechanical origin. Identify and compare clinical, morphological, disability, synov...

  • Review
  • Open Access
87 Citations
9,648 Views
25 Pages

Iron, Zinc, Copper, Cadmium, Mercury, and Bone Tissue

  • Żaneta Ciosek,
  • Karolina Kot and
  • Iwona Rotter

The paper presents the current understanding on the effects of five metals on bone tissue, namely iron, zinc, copper, cadmium, and mercury. Iron, zinc, and copper contribute significantly to human and animal metabolism when present in sufficient amou...

(This article belongs to the Section Environmental Health)
  • Review
  • Open Access
16 Citations
5,684 Views
21 Pages

Overview of Oxidative Stress in Systemic Lupus Erythematosus

  • Ancuta Lupu,
  • Gabriela Stoleriu,
  • Alin Horatiu Nedelcu,
  • Sara Nadeea Perju,
  • Cristina Gavrilovici,
  • Ginel Baciu,
  • Cristina Maria Mihai,
  • Tatiana Chisnoiu,
  • Ionela Daniela Morariu and
  • Vasile Valeriu Lupu
  • + 4 authors

Systemic lupus erythematosus (SLE) is an autoimmune disease that is frequently diagnosed in female patients, caused by multiple interacting factors. It has a complex pathogenesis which can affect almost any organ, from the kidneys to the cardiovascul...

(This article belongs to the Special Issue Exploring Biomarkers of Oxidative Stress in Health and Disease)
  • Article
  • Open Access
3 Citations
1,856 Views
15 Pages

Inherited Hemophilia—A Multidimensional Chronic Disease That Requires a Multidisciplinary Approach

  • Cristina Claudia Tarniceriu,
  • Loredana Liliana Hurjui,
  • Daniela Maria Tanase,
  • Anca Haisan,
  • Razvan Tudor Tepordei,
  • Gabriel Statescu,
  • Simona Alice Partene Vicoleanu,
  • Ancuta Lupu,
  • Vasile Valeriu Lupu and
  • Alin Horatiu Nedelcu
  • + 1 author

24 March 2025

Background: Articular damage is a marker of hereditary hemophilia, especially affecting the large joints of the upper and lower limbs. This retrospective study aimed to emphasize that hereditary coagulopathies, specifically hemophilia A and B, requir...

(This article belongs to the Special Issue Hemophilia)
  • Article
  • Open Access
4 Citations
5,260 Views
15 Pages

High-Risk Areas for Congenital Zika Syndrome in Rio de Janeiro: Spatial Cluster Detection

  • Danielle Amaral de Freitas,
  • Mayumi Duarte Wakimoto,
  • Sónia Dias and
  • Reinaldo Souza-Santos

Brazil reported 18,282 suspected congenital Zika syndrome (CZS) cases up to 2018 and accounts for 61.4% of the total reported Zika cases in the Americas in the period. To detect high-risk areas for children with CZS in the city of Rio de Janeiro, we...

(This article belongs to the Special Issue Recent Progress in Mosquito-Borne Diseases)
  • Review
  • Open Access
29 Citations
8,210 Views
18 Pages

The Outcomes of Robotic Rehabilitation Assisted Devices Following Spinal Cord Injury and the Prevention of Secondary Associated Complications

  • Carmen Delia Nistor-Cseppento,
  • Anamaria Gherle,
  • Nicoleta Negrut,
  • Simona Gabriela Bungau,
  • Anca Maria Sabau,
  • Andrei-Flavius Radu,
  • Alexa Florina Bungau,
  • Delia Mirela Tit,
  • Bogdan Uivaraseanu and
  • Diana Uivarosan
  • + 1 author

13 October 2022

Spinal cord injuries (SCIs) have major consequences on the patient’s health and life. Voluntary muscle paralysis caused by spinal cord damage affects the patient’s independence. Following SCI, an irreversible motor and sensory deficit occ...

  • Article
  • Open Access
3 Citations
3,376 Views
11 Pages

Essential Oil of Psidium glaziovianum Kiaersk Alleviates the Effects of Complete Freund’s Adjuvant (CFA)-Induced Arthritis by Regulating Inflammation and Oxidative Stress

  • Wêndeo Kennedy Costa,
  • João Victor de Oliveira Alves,
  • Beatriz Meyruze Barros Da Fonseca,
  • Valquíria Bruna Guimarães Silva,
  • Rafael Jardim Ferreira,
  • Thiago Henrique Napoleão,
  • Patrícia Maria Guedes Paiva,
  • Maria Tereza dos Santos Correia,
  • Alisson Macário de Oliveira and
  • Márcia Vanusa da Silva

Rheumatoid arthritis (RA) is a chronic and debilitating condition that affects a significant number of individuals worldwide. Unfortunately, the currently available therapeutic approaches often yield unsatisfactory results and may be accompanied by h...

(This article belongs to the Section Preclinical Research)
  • Article
  • Open Access
7 Citations
3,210 Views
28 Pages

Effect of Wear-Corrosion of Reduced Graphene Oxide Functionalized with Hyaluronic Acid on Inflammatory and Proteomic Response of J774A.1 Macrophages

  • Luna Sánchez-López,
  • Noelia Ropero de Torres,
  • Belén Chico,
  • Natalia Soledad Fagali,
  • Vivian de los Ríos,
  • María Lorenza Escudero,
  • María Cristina García-Alonso and
  • Rosa María Lozano

15 March 2023

The presence of a worn surface in the implanted material, as in the case of a replacement of a damaged osteoarticular joint, is the normal condition after implantation. This manuscript focuses precisely on the comparative study of the cellular behavi...

(This article belongs to the Section Metallic Functional Materials)
  • Article
  • Open Access
1,230 Views
10 Pages

Acquired Deforming Hypertonia in Afro-Caribbeans: A Cross-Sectional Analysis in Long-Term Care Units

  • Nicolas Kerjean,
  • Rishika Banydeen,
  • Bertrand Glize,
  • Michel Bonnet,
  • Patrick Rene-Corail,
  • Maturín Tabue Teguo,
  • Moustapha Dramé,
  • Patrick Dehail and
  • Jose-Luis Barnay

12 February 2025

Background: Osteoarticular deformities or contractures in institutionalized elderly individuals, described as acquired deforming hypertonia (ADH), have a multifactorial origin. The reported prevalence of ADH in French Caucasian patients in long-term...

(This article belongs to the Section Clinical Rehabilitation)
  • Article
  • Open Access
28 Citations
7,410 Views
19 Pages

Amorphous, Smart, and Bioinspired Polyphosphate Nano/Microparticles: A Biomaterial for Regeneration and Repair of Osteo-Articular Impairments In-Situ

  • Werner E. G. Müller,
  • Meik Neufurth,
  • Shunfeng Wang,
  • Maximilian Ackermann,
  • Rafael Muñoz-Espí,
  • Qingling Feng,
  • Qiang Lu,
  • Heinz C. Schröder and
  • Xiaohong Wang

Using femur explants from mice as an in vitro model, we investigated the effect of the physiological polymer, inorganic polyphosphate (polyP), on differentiation of the cells of the bone marrow in their natural microenvironment into the osteogenic an...

(This article belongs to the Special Issue Bioactive Nanoparticles)
  • Article
  • Open Access
5 Citations
3,333 Views
21 Pages

Exploring the Mechanism of Topical Application of Clematis Florida in the Treatment of Rheumatoid Arthritis through Network Pharmacology and Experimental Validation

  • Ting Lei,
  • Chang Jiang,
  • Li Zhao,
  • Jizhou Zhang,
  • Qing Xiao,
  • Yanhong Chen,
  • Jie Zhang,
  • Chunquan Zhou,
  • Gong Wang and
  • Jing Han

Clematis Florida (CF) is a folk medicinal herb in the southeast of China, which is traditionally used for treating osteoarticular diseases. However, the mechanism of its action remains unclear. The present study used network pharmacology and experime...

(This article belongs to the Section Pharmacology)
  • Article
  • Open Access
6 Citations
4,789 Views
23 Pages

16 June 2024

Background: The sulfide–hydrogen sulfide brine balneotherapy (HSBB), including a combination of dissolved hydrogen sulfide (H2S) gas, inorganic sulfur ions (S2−), and hydrosulfide ions (HS−), is one of the most important and most ef...

(This article belongs to the Section Cardiology)