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35 Results Found

  • Article
  • Open Access
25 Citations
8,531 Views
11 Pages

1 September 2018

The efficacy of oral rehydration solution (ORS) enriched with Lactobacillus reuteri DSM 17938 and zinc in infants with acute gastroenteritis, is poorly defined. The aim of this double-blind, randomized, placebo-controlled study, was to assess the eff...

  • Article
  • Open Access
5 Citations
23,674 Views
13 Pages

12 November 2023

The effects of varying sodium (Na) and carbohydrate (CHO) in oral rehydration solutions (ORS) and sports drinks (SD) for rehydration following exercise are unclear. We compared an ORS and SD for the percent of fluid retained (%FR) following exercise-...

  • Review
  • Open Access
6 Citations
10,465 Views
16 Pages

The original studies demonstrating the efficacy of oral glucose-electrolytes solutions in reducing or eliminating the need for intravenous therapy to correct dehydration caused by acute watery diarrheas (AWD) were focused chiefly on cholera patients....

  • Review
  • Open Access
2 Citations
3,703 Views
15 Pages

Enteral Resuscitation: A Field-Expedient Treatment Strategy for Burn Shock during Wartime and in Other Austere Settings

  • Ian F. Jones,
  • Kiran Nakarmi,
  • Hannah B. Wild,
  • Kwesi Nsaful,
  • Kajal Mehta,
  • Raslina Shrestha,
  • Daniel Roubik and
  • Barclay T. Stewart

18 January 2024

Burn injuries are a constant threat in war. Aspects of the modern battlefield increase the risk of burn injuries and pose challenges for early treatment. The initial resuscitation of a severely burn-injured patient often exceeds the resources availab...

  • Article
  • Open Access
10 Citations
10,467 Views
10 Pages

29 June 2019

Oral rehydration solutions (ORS) are specifically formulated with an osmolality to optimize fluid absorption. However, it is unclear how many ORS products comply with current World Health Organization (WHO) osmolality guidelines and the osmotic shelf...

  • Article
  • Open Access
3 Citations
3,305 Views
12 Pages

Lower Rate of Water Absorption of an Oral Rehydration Solution with Partially Hydrolyzed Guar Gum in Conscious Rats

  • Toru Takahashi,
  • Miki Tokunaga,
  • Tsutomu Okubo,
  • Makoto Ozeki,
  • Mahendra P. Kapoor and
  • Zenta Yasukawa

11 October 2022

The purpose of the present study was to elucidate the rate of water absorption of an oral rehydration solution containing partially hydrolyzed guar gum (PHGG) in the small intestine, which is the main site of water absorption when water is drunk. Sev...

  • Article
  • Open Access
2 Citations
7,301 Views
6 Pages

For ORT to have a maximum impact on public health it should be used in the community, in the home. A number of programs have been developed over the years to extend ORT to home use. One of the most successful approaches was the Oral Therapy Education...

  • Review
  • Open Access
16 Citations
29,257 Views
29 Pages

Compositional Aspects of Beverages Designed to Promote Hydration Before, During, and After Exercise: Concepts Revisited

  • Íñigo M. Pérez-Castillo,
  • Jennifer A. Williams,
  • José López-Chicharro,
  • Niko Mihic,
  • Ricardo Rueda,
  • Hakim Bouzamondo and
  • Craig A. Horswill

20 December 2023

Hypohydration can impair aerobic performance and deteriorate cognitive function during exercise. To minimize hypohydration, athletes are recommended to commence exercise at least euhydrated, ingest fluids containing sodium during long-duration and/or...

  • Article
  • Open Access
8 Citations
4,977 Views
13 Pages

Sensory Perception of an Oral Rehydration Solution during Exercise in the Heat

  • Olivia Kitson,
  • Kay Rutherfurd-Markwick,
  • Andrew Foskett,
  • Jason Kai Wei Lee,
  • Charles Diako,
  • Marie Wong and
  • Ajmol Ali

23 September 2021

Prolonged exercise in the heat elicits a number of physiological changes as glycogen stores are low and water and electrolytes are lost through sweat. However, it is unclear whether these changes provoke an increase in liking of saltiness and, theref...

  • Article
  • Open Access
19 Citations
9,366 Views
16 Pages

15 December 2020

This study investigated the efficacy of ingesting an oral rehydration solution (DD) that has a high electrolyte concentration after exercise on fluid balance and cycling performance in comparison with a sports drink (SD) and water (WA). Nine healthy...

  • Review
  • Open Access
4,869 Views
11 Pages

Dietary Interventions for Short Bowel Syndrome in Adults

  • Cassandra Pogatschnik and
  • Lindsey Russell

1 July 2025

Short bowel syndrome (SBS) is a rare but complex medical condition that requires expertise in management. The etiology in adults is commonly surgical resection for Crohn’s disease or mesenteric ischemia and is classified based on the anatomy of...

  • Article
  • Open Access
2,425 Views
14 Pages

Mitigating Diarrhoea-Related Inflammation in Frail Older Adults with Postbiotic-Enhanced Oral Rehydration Solution: Insights from a Randomised, Double-Blind, Placebo-Controlled Study

  • Julian Andrés Mateus Rodríguez,
  • Patricia Rodríguez Sanz,
  • Edgar Kostandyan,
  • Rubén Palacios Sanchez,
  • María Luz Pino Roque,
  • Patricia Chaves Vasquez and
  • Pedro Roy Millán

Background/Objectives: Diarrhoea in older adults can lead to dehydration and malnutrition, impaired gut barrier function, and reduced quality of life. Unresolved inflammation during diarrhoea episodes contributes to relapse and complications. This ra...

  • Article
  • Open Access
2 Citations
5,647 Views
8 Pages

Acute Diarrhoea in Children: Determination of Duration Using a Combined Bismuth Hydroxide Gel and Oral Rehydration Solution Therapy vs. Oral Rehydration Solution

  • Adriana Oviedo,
  • Mirna Díaz,
  • María Laura Valenzuela,
  • Victoria Vidal,
  • Liliana Racca,
  • Hebe Bottai,
  • Graciela Priore,
  • Graciela Peluffo,
  • Susana Di Bartolomeo and
  • Graciela Cabral
  • + 1 author

21 December 2016

Oral rehydration salt (ORS) treatment in young children with acute diarrhoea (AD) has contributed to decrease mortality associated with dehydration although effective strategies to reduce morbidity associated with this disease are required. The aim o...

  • Brief Report
  • Open Access
11 Citations
1 Views
3 Pages

16 September 2010

Acute gastroenteritis is one of the most common infectious diseases of childhood. Its symptoms are vomiting, diarrhea, and dehydration. In the emergency ward, intravenous rather than oral rehydration is usually preferred because of the high likelihoo...

  • Article
  • Open Access
5 Citations
4,027 Views
11 Pages

Diarrhea is a common cause of child-related hospitalization and mortality among children under the age of five in South Africa. This study was conducted to assess the knowledge and practices of caregivers regarding prevention and management of diarrh...

  • Article
  • Open Access
6 Citations
4,973 Views
18 Pages

Childhood Diarrhea Prevalence and Uptake of Oral Rehydration Solution and Zinc Treatment in Nigeria

  • Bolaji Emmanuel Egbewale,
  • Omar Karlsson and
  • Christopher Robert Sudfeld

9 November 2022

Given the disproportionate burden of childhood diarrhea deaths in Nigeria, this study assessed the prevalence and predictors of the disease and the uptake of ORS and zinc supplementation as treatments in a population-based national survey. Cross-sect...

  • Article
  • Open Access
5 Citations
6,369 Views
8 Pages

Maintenance Fluid Therapy with Saline, Dextrose-Supplemented Saline or Lactated Ringer in Childhood: Short-Term Metabolic Effects

  • Alessandra Ricciuti,
  • Gregorio P. Milani,
  • Silvia Tarantino,
  • Roberta Ghilardi,
  • Sebastiano A.G. Lava,
  • Marco Alberzoni,
  • Mario G. Bianchetti and
  • Carlo Agostoni

17 May 2020

Maintenance with isotonic fluids is recommended in children with gastroenteritis and failure of oral rehydration therapy. However, little is known on the short-term effects of the commonly prescribed intravenous solutions on metabolic balance in chil...

  • Article
  • Open Access
46 Citations
2,384 Views
8 Pages

Study of Thermo-Sensitive In-Situ Gels for Ocular Delivery

  • Manas BHOWMIK,
  • Sanchita DAS,
  • Dipankar CHATTOPADHYAY and
  • Lakshmi K. GHOSH

5 March 2011

The aim of the present study was the development of thermo-sensitive in-situ gels for in-vitro evaluation of ophthalmic delivery systems of ketorolac tromethamine (KT), based on methylcellulose (MC) in combination with hydroxypropylmethyl cellulose (...

  • Article
  • Open Access
5 Citations
3,024 Views
13 Pages

Synergistic Effect of Postbiotic Yeast ABB C22® on Gut Inflammation, Barrier Function, and Protection from Rotavirus Infection in In Vitro Models

  • Lydia Carrera Marcolin,
  • Jordi Cuñé Castellana,
  • Laia Martí Melero,
  • Carlos de Lecea and
  • Maria Tintoré Gazulla

Diarrhoea is a serious cause of mortality worldwide that can lead to dehydration, gut barrier function impairment, nutrient malabsorption, and alterations of the gut microbiota (dysbiosis). The current solutions for its management, such as oral rehyd...

  • Article
  • Open Access
1,046 Views
21 Pages

21 July 2025

Background: The differential effects of post-exercise rehydration beverages on inflammatory processes and organ protection remain incompletely characterized. This study investigated how beverages with distinct compositions influence urinary biomarker...

  • Article
  • Open Access
11 Citations
4,594 Views
12 Pages

Rural populations living in poverty are the most vulnerable to disaster. Despite this increased risk of recurrent disaster, previous disaster experience is not a good predictor for disaster preparedness in these populations. This was evidenced on 31...

  • Article
  • Open Access
4 Citations
7,231 Views
11 Pages

Incidence and Risk Factors for Severe Dehydration in Hospitalized Children in Ujjain, India

  • Abhishek Sharma,
  • Aditya Mathur,
  • Cecilia Stålsby Lundborg and
  • Ashish Pathak

Diarrhoea contributes significantly to the under-five childhood morbidity and mortality worldwide. This cross-sectional study was carried out in a tertiary care hospital in Ujjain, India from July 2015 to June 2016. Consecutive children aged 1 month...

  • Article
  • Open Access
6 Citations
6,519 Views
12 Pages

Childhood diarrhea continues to be a major cause of under-five (U-5) mortality globally and in India. In this study, 1571 U-5 children residing in nine rural villages and four urban slums in Ujjain, India were included with the objective to use commu...

  • Article
  • Open Access
18 Citations
5,701 Views
18 Pages

Improved Water and Waste Management Practices Reduce Diarrhea Risk in Children under Age Five in Rural Tanzania: A Community-Based, Cross-Sectional Analysis

  • Paul H. McClelland,
  • Claire T. Kenney,
  • Federico Palacardo,
  • Nicholas L. S. Roberts,
  • Nicholas Luhende,
  • Jason Chua,
  • Jennifer Huang,
  • Priyanka Patel,
  • Leonardo Albertini Sanchez and
  • Won J. Kim
  • + 3 authors

Diarrhea remains a significant cause of morbidity and mortality among children in developing countries. Water, sanitation, and hygiene practices (WASH) have demonstrated improved diarrhea-related outcomes but may have limited implementation in certai...

  • Article
  • Open Access
1 Citations
2,250 Views
12 Pages

26 November 2024

Background: Community pharmacists are frequently approached by patients seeking health advice for minor ailments, particularly for common childhood diseases like diarrhea. Globally, approximately two million children under five years of age die each...

  • Article
  • Open Access
1 Citations
1,832 Views
12 Pages

Intermittent Preventive Treatment of Malaria in Pregnancy and the Impact on Neonates in African Countries as Assessed by Entropy Weight and TOPSIS Methods

  • Maria Tzitiridou-Chatzopoulou,
  • Georgia Zournatzidou,
  • Eirini Orovou,
  • Lazaros Lavasidis,
  • Arsenios Tsiotsias,
  • Panagiotis Eskitzis and
  • Dimitrios Papoutsis

18 October 2024

Background/Objectives: In regions of Africa with a high prevalence of malaria, pregnant women in their first or second trimester should be administered intermittent preventive treatment in pregnancy (IPTp). However, infants may contract malaria despi...

  • Article
  • Open Access
7 Citations
3,045 Views
11 Pages

Randomized Controlled Trial of the Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Cholera Rapid Response Program to Reduce Diarrheal Diseases in Bangladesh

  • Christine Marie George,
  • Tahmina Parvin,
  • Md. Sazzadul Islam Bhuyian,
  • Ismat Minhaj Uddin,
  • Fatema Zohura,
  • Jahed Masud,
  • Shirajum Monira,
  • David A. Sack,
  • Jamie Perin and
  • Munirul Alam
  • + 1 author

(a) Objective: To build an evidence base on effective water, sanitation, and hygiene interventions to reduce diarrheal diseases in cholera hotspots, we developed the CHoBI7 Cholera Rapid Response Program. (b) Methods: Once a cholera patient (confirme...

  • Article
  • Open Access
19 Citations
4,404 Views
24 Pages

12 April 2021

Many mathematical models have explored the dynamics of cholera but none have been used to predict the optimal strategies of the three control interventions (the use of hygiene promotion and social mobilization; the use of treatment by drug/oral re-hy...

  • Article
  • Open Access
3 Citations
3,038 Views
13 Pages

Effect of a Water, Sanitation, and Hygiene Program on Handwashing with a Cleansing Agent among Diarrhea Patients and Attendants in Healthcare Facilities in the Democratic Republic of the Congo: A Randomized Pilot of the PICHA7 Program

  • Alain Mwishingo,
  • Kelly Endres,
  • Lucien Bisimwa,
  • Presence Sanvura,
  • Blessing Muderhwa Banywesize,
  • Jean-Claude Bisimwa,
  • Camille Williams,
  • Jamie Perin,
  • Raissa Boroto and
  • Gisèle Nsimire
  • + 10 authors

Healthcare-acquired infections are a major problem in healthcare facility settings around the world. The Democratic Republic of the Congo (DRC) has over 2 million diarrhea patients hospitalized each year. These healthcare settings become high-risk en...

  • Article
  • Open Access
10 Citations
4,604 Views
14 Pages

Care-Seeking for Diarrhoea in Southern Malawi: Attitudes, Practices and Implications for Diarrhoea Control

  • Salule Masangwi,
  • Neil Ferguson,
  • Anthony Grimason,
  • Tracy Morse and
  • Lawrence Kazembe

This paper examined care-seeking behaviour and its associated risk factors when a family member had diarrhoea. Data was obtained from a survey conducted in Chikwawa, a district in Southern Malawi. Chikwawa is faced with a number of environmental and...

  • Article
  • Open Access
1 Citations
2,655 Views
11 Pages

5 April 2024

The WHO and UNICEF recommend that only breastmilk, vitamin drops, oral rehydration solution, and prescribed medicine can go through the infant’s mouth. Non-prescribed medications (NPM) include over-the-counter medications and traditional medici...

  • Article
  • Open Access
13 Citations
5,384 Views
17 Pages

27 July 2023

Poor nutrition outcomes among children have become one of the major public health concerns in South Africa, attributed to poor feeding practices and maternal nutrition-related knowledge with conflicting data. In view of this, a cross-sectional study...