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16 Results Found

  • Article
  • Open Access

Differential Associations of Lipopolysaccharide, Soluble NOX2-Derived Peptide, and Hydrogen Peroxide with Adiposity and Muscularity in Adults on Maintenance Hemodialysis

  • Giovanni Imbimbo,
  • Federica Foti,
  • Thomas Ammann,
  • Maria Grazia Chiappini,
  • Vittoria Cammisotto,
  • Valentina Castellani,
  • Pasquale Pignatelli and
  • Alessio Molfino

11 September 2026

Background: Endotoxemia and oxidative stress may contribute to adverse body-composition changes in patients receiving maintenance hemodialysis, but their relationships with adiposity and muscularity remain incompletely defined. We investigated whethe...

(This article belongs to the Special Issue Antioxidants in Chronic and End-Stage Kidney Disease: Defining Biological and Clinical Plausibility)
  • Article
  • Open Access
39 Citations
46,004 Views
19 Pages

Fasting: How to Guide

  • Alda Attinà,
  • Claudia Leggeri,
  • Rita Paroni,
  • Francesca Pivari,
  • Michele Dei Cas,
  • Alessandra Mingione,
  • Maria Dri,
  • Marco Marchetti and
  • Laura Di Renzo

7 May 2021

Fasting potentials are the most interesting topics in the Nutritional Era. Fasting consists of the catabolism of lipids, proteins, and carbohydrates to maintain blood glucose levels in a normal range. The action mechanisms of fasting were firstly und...

(This article belongs to the Special Issue Calorie Restriction’s Effects on Health and Disease: From Basic Research to Human Health)
  • Article
  • Open Access
3 Citations
3,498 Views
13 Pages

Estimating Dietary Protein and Sodium Intake with Sodium Removal in Peritoneal Dialysis Patients

  • Ana Bontić,
  • Aleksandra Kezić,
  • Jelena Pavlović,
  • Marko Baralić,
  • Selena Gajić,
  • Kristina Petrovic,
  • Vidna Karadžić Ristanović,
  • Olga Petrović,
  • Vera Stjepanović and
  • Milan Radović
  • + 1 author

19 August 2024

An increase in dietary protein intake (DPI) carries a risk with respect to increased sodium intake, which further leads to the development of cardiovascular morbidity in peritoneal dialysis (PD) patients. Dialytic (DSR) and urinary sodium removal (US...

(This article belongs to the Special Issue Impact of Macronutrients on Metabolism)
  • Article
  • Open Access
101 Citations
12,222 Views
12 Pages

18 April 2017

Protein-energy wasting (PEW) is associated with mortality in patients with end-stage renal disease (ESRD) on maintenance hemodialysis. The correct diagnosis of PEW is extremely important in order to predict clinical outcomes. However, it is unclear w...

(This article belongs to the Special Issue Nutrition and Chronic Kidney Disease)
  • Article
  • Open Access
17 Citations
5,999 Views
11 Pages

Compliance, Adherence and Concordance Differently Predict the Improvement of Uremic and Microbial Toxins in Chronic Kidney Disease on Low Protein Diet

  • Andreana De Mauri,
  • Deborah Carrera,
  • Matteo Vidali,
  • Marco Bagnati,
  • Roberta Rolla,
  • Sergio Riso,
  • Massimo Torreggiani and
  • Doriana Chiarinotti

23 January 2022

Background. In medicine, “compliance” indicates that the patient complies with the prescriber’s recommendations, “adherence” means that “the patient matches the recommendations” and “concordance”...

(This article belongs to the Special Issue Nutritional Approach for Patients with Advanced CKD)
  • Article
  • Open Access
10 Citations
3,659 Views
24 Pages

Transcriptomic Analysis of Liver in Silver sillago, Sillago sihama Fed with High-Level Low-Gossypol Cottonseed Meal in Replacement of Fishmeal Diet

  • Hao Liu,
  • Menglong Zhou,
  • Xiaohui Dong,
  • Beiping Tan,
  • Shuang Zhang,
  • Yuanzhi Yang,
  • Shuyan Chi,
  • Hongyu Liu,
  • Xiaobo Yan and
  • Zhihao Li

29 March 2023

Understanding the molecular mechanisms involved in adaptation to alternate diets has become a significant concern, as increasing amounts of fishmeal (FM) protein in aquafeeds are being substituted with plant protein. Thus, the goal of this study was...

(This article belongs to the Collection A Sustainable Approach to Non-Conventional Feeding Resources and Rearing Strategies)
  • Article
  • Open Access
6 Citations
3,419 Views
15 Pages

The Association between Nutritional Markers and Heart Rate Variability Indices in Patients Undergoing Chronic Hemodialysis

  • Eric Chien-Hwa Wu,
  • Ya-Ting Huang,
  • Yu-Ming Chang,
  • I-Ling Chen,
  • Chuan-Lan Yang,
  • Show-Chin Leu,
  • Hung-Li Su,
  • Jsun-Liang Kao,
  • Shih-Ching Tsai and
  • + 2 authors

16 October 2019

The associations between nutritional markers and heart rate variability (HRV) are poorly addressed. This study aimed to evaluate whether malnutrition is associated with the altered autonomic nervous system (ANS) function. This cross-sectional study w...

(This article belongs to the Special Issue Autonomic Nervous System: From Bench to Bedside)
  • Article
  • Open Access
23 Citations
6,248 Views
14 Pages

Transcriptomic Changes Induced by Drought Stress in Hardneck Garlic during the Bolting/Bulbing Stage

  • Xiangjun Zhou,
  • Jorge Alberto Condori-Apfata,
  • Xiaoqin Liu,
  • Sandro Jhonatan Condori-Pacsi,
  • Maria Valderrama Valencia and
  • Cankui Zhang

29 January 2021

Garlic (Allium sativum L.) is an economically important, monocotyledonous plant with a strong taste and odor. Drought stress adversely affects its growth, development, and yield, particularly during the bolting/bulbing stage. Herein we performed RNA-...

(This article belongs to the Special Issue Horticultural Genetics and Biotechnology)
  • Article
  • Open Access
337 Views
25 Pages

Cross-Tissue Transcriptomic Convergence Identifies a Leuko-Cyte-Shared, Myeloid-Enriched Inflammatory Program in Frailty and Osteoarthritis

  • Wang Wei,
  • Bingxiao Pan,
  • Ruiying Li,
  • Dazhi Wang,
  • Zhihao Chen,
  • Zenan Tian,
  • Yisen Feng,
  • Zhikun Jia,
  • Jiajun Jiang and
  • Zhibin Shi
  • + 2 authors

Frailty and osteoarthritis (OA) frequently coexist in older adults, yet the extent to which they share molecular programs across tissues remains unclear. We integrated bulk transcriptomics, peripheral immune and OA meniscal single-cell atlases, infer...

(This article belongs to the Special Issue Systems Medicine Approaches for Human Diseases: Data Integration, Modeling, and Therapeutic Insights)
  • Article
  • Open Access
9 Citations
3,712 Views
8 Pages

26 September 2019

Background: Latent tuberculosis infection (LTBI) is prevalent in end-stage renal disease (ESRD) patients. The risk of tuberculosis activation is also high. The appropriate LTBI screening and treatment is required in this population. Meanwhile, whethe...

  • Article
  • Open Access
11 Citations
6,426 Views
12 Pages

Safety and Efficacy of Short Daily Hemodialysis with Physidia S3 System: Clinical Performance Assessment during the Training Period

  • Hafedh Fessi,
  • Jean-Christophe Szelag,
  • Cécile Courivaud,
  • Philippe Nicoud,
  • Didier Aguilera,
  • Olivia Gilbert,
  • Marion Morena,
  • Michel Thomas,
  • Bernard Canaud and
  • Jean-Paul Cristol

11 April 2022

Background: A growing body of scientific evidence indicates that clinical outcomes of hemodialysis patients can be improved with short daily dialysis treatment. Current in-center hemodialysis machines do not fulfill the requirements needed for self-c...

(This article belongs to the Collection Clinical Research and Advances in Hemodialysis)
  • Article
  • Open Access
34 Citations
6,355 Views
9 Pages

Ubiquitin Carboxyl-Terminal Hydrolases (UCHs): Potential Mediators for Cancer and Neurodegeneration

  • Amit Sharma,
  • Hongde Liu,
  • Fabian Tobar-Tosse,
  • Tikam Chand Dakal,
  • Michael Ludwig,
  • Frank G. Holz,
  • Karin U. Loeffler,
  • Ullrich Wüllner and
  • Martina C. Herwig-Carl

Emerging evidence suggests an inverse association between cancer and neurodegenerative diseases (NDD). Although phenotypically different, both diseases display a significant imbalance in the ubiquitination/deubiquitination processes. Therefore, we pa...

(This article belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
  • Article
  • Open Access
3 Citations
1,405 Views
28 Pages

23 September 2025

Background: Malnutrition is common in chronic hemodialysis (HD) patients and often remains underdiagnosed. While body composition, functional status, and anthropometric measures can support nutritional assessment, their associations with nutritional...

(This article belongs to the Special Issue Nutritional Status and the Risk of Malnutrition in People with Kidney Failure)
  • Article
  • Open Access
5 Citations
3,247 Views
18 Pages

Protective Effect of Knee Postoperative Fluid on Oxidative-Induced Damage in Human Knee Articular Chondrocytes

  • Roberta Giordo,
  • Smitha Tulasigeri Totiger,
  • Gianfilippo Caggiari,
  • Annalisa Cossu,
  • Andrea Fabio Manunta,
  • Anna Maria Posadino and
  • Gianfranco Pintus

1 February 2024

The oxidative-stress-elicited deterioration of chondrocyte function is the initial stage of changes leading to the disruption of cartilage homeostasis. These changes entail a series of catabolic damages mediated by proinflammatory cytokines, MMPs, an...

(This article belongs to the Section ROS, RNS and RSS)
  • Article
  • Open Access
1 Citations
1,852 Views
10 Pages

Assessing Cross-Sectional Association of Uremic Pruritus with Serum Heavy Metal Levels: A Single-Center Study

  • Cheng-Hao Weng,
  • Ching-Chih Hu,
  • Tzung-Hai Yen,
  • Ching-Wei Hsu and
  • Wen-Hung Huang

29 November 2023

(1) Background: Uremic pruritus (UP) is a common and taxing symptom in patients on maintenance hemodialysis (MHD). We have previously shown that blood lead levels (BLLs) and blood aluminum levels (BALs) were separately positively associated with UP i...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Concept Paper
  • Open Access
30 Citations
8,018 Views
23 Pages

Prescribing Hemodialysis or Hemodiafiltration: When One Size Does Not Fit All the Proposal of a Personalized Approach Based on Comorbidity and Nutritional Status

  • Giorgina Barbara Piccoli,
  • Louise Nielsen,
  • Lurilyn Gendrot,
  • Antioco Fois,
  • Emanuela Cataldo and
  • Gianfranca Cabiddu

8 October 2018

There is no simple way to prescribe hemodialysis. Changes in the dialysis population, improvements in dialysis techniques, and different attitudes towards the initiation of dialysis have influenced treatment goals and, consequently, dialysis prescrip...

(This article belongs to the Section Hematology)