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28 Results Found

  • Article
  • Open Access
3 Citations
4,244 Views
8 Pages

The Octopus Sign—A New HRCT Sign in Pulmonary Langerhans Cell Histiocytosis

  • Alexander Poellinger,
  • Sabina Berezowska,
  • Jeffrey Leon Myers,
  • Adrian Huber,
  • Manuela Funke-Chambour,
  • Sabina Guler,
  • Thomas Geiser,
  • Sergio Harari,
  • Antonella Caminati and
  • Nicola Sverzellati
  • + 1 author

Background: Fibrosis in pulmonary Langerhans cell histiocytosis (PLCH) histologically comprises a central scar with septal strands and associated airspace enlargement that produce an octopus-like appearance. The purpose of this study was to identify...

  • Review
  • Open Access
2 Citations
3,006 Views
21 Pages

The Burden of Non-Infectious Organ-Specific Immunopathology in Pediatric Common Variable Immunodeficiency

  • Aleksandra Szczawińska-Popłonyk,
  • Julia Bekalarska,
  • Kacper Jęch,
  • Nadia Knobloch,
  • Oliwia Łukasik,
  • Aleksandra Ossowska,
  • Jędrzej Ruducha and
  • Zuzanna Wysocka

The pediatric common variable immunodeficiency (CVID) is the most frequent symptomatic antibody production defect characterized by infectious and non-infectious autoimmune, inflammatory, and lymphoproliferative complications. The background for CVID-...

  • Case Report
  • Open Access
1 Citations
775 Views
5 Pages

Guzkowy Rozrost Limfoidalny—Rzadki Przypadek Choroby Limfoproliferacyjnej w Płucach

  • Paweł Rogoziński,
  • Krzysztof Bruliński,
  • Eugeniusz Malinowski,
  • Piotr Wandzel and
  • Marek Kucharzewski

13 December 2012

Nodular lymphoid hyperplasia (NLH) belongs to a very rare, mild, lymphoproliferative disease of unestablished aetiology historically included in the group of pseudolymphomas. Its existence was controversial for many years, until modern techniques of...

  • Case Report
  • Open Access
3,239 Views
8 Pages

Bilateral Diffuse Nodular Pulmonary Ossification Mimicking Metastatic Disease in a Patient with Fibrolamellar Hepatocellular Carcinoma

  • Pattamon Sutthatarn,
  • Cara E. Morin,
  • Jessica Gartrell,
  • Wayne L. Furman,
  • Max R. Langham,
  • Teresa Santiago and
  • Andrew J. Murphy

16 March 2021

Pulmonary ossification (PO) is a rare finding, characterized by mature bone formation in the lung parenchyma. We report a 20-year-old female patient diagnosed with fibrolamellar hepatocellular carcinoma (FL-HCC) and bilateral diffuse nodular PO. The...

  • Review
  • Open Access
4 Citations
12,584 Views
35 Pages

17 April 2024

Interlobular septa thickening (ILST) is a common and easily recognized feature on computed tomography (CT) images in many lung disorders. ILST thickening can be smooth (most common), nodular, or irregular. Smooth ILST can be seen in pulmonary edema,...

  • Review
  • Open Access
6 Citations
9,342 Views
19 Pages

Lung Involvement in Pulmonary Vasculitis: A Radiological Review

  • Luca Gozzi,
  • Diletta Cozzi,
  • Giulia Zantonelli,
  • Caterina Giannessi,
  • Simona Giovannelli,
  • Olga Smorchkova,
  • Giulia Grazzini,
  • Elena Bertelli,
  • Alessandra Bindi and
  • Vittorio Miele
  • + 2 authors

Pulmonary vasculitis identifies a heterogeneous group of diseases characterized by inflammation, damage and necrosis of the wall of pulmonary vessels. The most common approach to classify vasculitis is according to etiology, therefore dividing them i...

  • Article
  • Open Access
4 Citations
7,609 Views
15 Pages

Lung and Intercostal Upper Abdomen Ultrasonography for Staging Patients with Ovarian Cancer: A Method Description and Feasibility Study

  • Maciej Stukan,
  • Antonio Bugalho,
  • Amanika Kumar,
  • Julita Kowalewska,
  • Dariusz Świetlik,
  • Natalia Buda,
  • Małgorzata Pietrzak-Stukan and
  • Mirosław Dudziak

A detailed transabdominal and transvaginal ultrasound examination, performed by an expert examiner, could render a similar diagnostic performance to computed tomography for assessing pelvic/abdominal tumor spread disease in women with epithelial ovar...

  • Interesting Images
  • Open Access
1 Citations
2,655 Views
7 Pages

Pulmonary Amyloidoma: A Case Report and Brief Review of the Literature

  • Matache Radu Șerban,
  • Savu Cornel Florentin and
  • Constantin Ancuta Alina

9 November 2023

We report the case of a 59-year-old female patient, a former smoker, who was diagnosed with bilateral pulmonary nodules. Extensive medical investigations were conducted, including a surgical lung biopsy, which led to the diagnosis of pulmonary amyloi...

  • Review
  • Open Access
33 Citations
8,878 Views
15 Pages

Cytomegalovirus (CMV) Pneumonitis: Cell Tropism, Inflammation, and Immunity

  • Luís Fonseca Brito,
  • Wolfram Brune and
  • Felix R. Stahl

Human cytomegalovirus (HCMV) is an opportunistic pathogen causing disease mainly in immunocompromised patients or after congenital infection. HCMV infection of the respiratory tract leads to pneumonitis in the immunocompromised host, which is often a...

  • Article
  • Open Access
12 Citations
2,730 Views
10 Pages

Cardiovascular and Lung Involvement in Patients with Autoimmune Pancreatitis

  • Sara Nikolic,
  • Katharina Brehmer,
  • Nikola Panic,
  • Roberto Valente,
  • J.-Matthias Löhr and
  • Miroslav Vujasinovic

3 February 2020

Introduction: Immunoglobulin G4-related disease (IgG4-RD) is a systemic immune-mediated disease characterised pathologically by the infiltration of IgG4-bearing plasma cells into the involved organs. Autoimmune pancreatitis (AIP) is a form of chronic...

  • Article
  • Open Access
8 Citations
3,574 Views
13 Pages

Mycobacterium Tuberculosis and Avium Complex Investigation among Malaysian Free-Ranging Wild Boar and Wild Macaques at Wildlife-Livestock-Human Interface

  • Yusuf Madaki Lekko,
  • Azlan Che-Amat,
  • Peck Toung Ooi,
  • Sharina Omar,
  • Siti Zubaidah Ramanoon,
  • Mazlina Mazlan,
  • Faez Firdaus Abdullah Jesse,
  • Sabri Jasni and
  • Mohd Firdaus Ariff Abdul-Razak

13 November 2021

Wild animals are considered reservoirs, contributing to the transmission of emerging zoonotic diseases such as tuberculosis (TB). A cross-sectional study was conducted by opportunistic sampling from fresh carcasses of free-ranging wild boar (n = 30),...

  • Interesting Images
  • Open Access
3,536 Views
4 Pages

A “Galactic” Chest X-ray

  • Cristiano Carbonelli,
  • Angela de Matthaeis,
  • Antonio Mirijello,
  • Concetta Di Micco,
  • Evaristo Maiello,
  • Salvatore De Cosmo and
  • Paolo Graziano

Clinical manifestations accompanying respiratory failure with insidious and rapidly progressive onset are often non-specific. Symptoms such as a cough, dyspnea, and fever are common to a large number of inflammatory, infectious, or neoplastic disease...

  • Case Report
  • Open Access
12 Citations
4,651 Views
12 Pages

Pneumoconiosis with a Sarcoid-Like Reaction Other than Beryllium Exposure: A Case Report and Literature Review

  • Fumiko Hayashi,
  • Takashi Kido,
  • Noriho Sakamoto,
  • Yoshiaki Zaizen,
  • Mutsumi Ozasa,
  • Mitsuru Yokoyama,
  • Hirokazu Yura,
  • Atsuko Hara,
  • Hiroshi Ishimoto and
  • Hiroshi Mukae
  • + 6 authors

22 November 2020

Background: Chronic beryllium disease (CBD) is a granulomatous disease that resembles sarcoidosis but is caused by beryllium. Clinical manifestations similar to those observed in CBD have occasionally been reported in exposure to dusts of other metal...

  • Review
  • Open Access
9 Citations
4,027 Views
15 Pages

Nontuberculous Mycobacteria, Mucociliary Clearance, and Bronchiectasis

  • Miriam Retuerto-Guerrero,
  • Ramiro López-Medrano,
  • Elizabeth de Freitas-González and
  • Octavio Miguel Rivero-Lezcano

Nontuberculous mycobacteria (NTM) are environmental and ubiquitous, but only a few species are associated with disease, often presented as nodular/bronchiectatic or cavitary pulmonary forms. Bronchiectasis, airways dilatations characterized by chroni...

  • Article
  • Open Access
1 Citations
3,715 Views
10 Pages

18 April 2024

The premortem understanding of the role of feline coronavirus (FeCoV) in the lungs of cats is limited as viruses are seldom inspected in the bronchoalveolar lavage (BAL) specimens of small animal patients. This study retrospectively analyzed the prev...

  • Review
  • Open Access
1 Citations
1,869 Views
18 Pages

DICER1 Syndrome: What Do We Know of the Pathogenetic Mechanisms?

  • Floor A. Jansen,
  • Jette Bakhuizen,
  • Lennart Kester and
  • Ronald R. de Krijger

2 September 2025

DICER1 syndrome is a hereditary cancer predisposition syndrome, characterized by a large range of benign and malignant neoplasms. Patients with DICER1 syndrome have a broad phenotype, with pleuropulmonary blastoma, Sertoli–Leydig cell tumor, cy...

  • Interesting Images
  • Open Access
1,724 Views
6 Pages

A Rare Case of Invasive Thyroid Aspergillosis Revealed on 18F-FDG-PET/CT

  • Ayoub Jaafari,
  • Sohaïb Mansour,
  • Laetitia Lebrun,
  • Keitiane Kaefer and
  • Rachid Attou

Invasive aspergillosis (IA) represents a common form of fungal infection caused by various species of Aspergillus that most frequently affect immunocompromised patients. Typically, this disease occurs preferentially in high-risk groups including pati...

  • Review
  • Open Access
3 Citations
3,926 Views
9 Pages

Catamenial Pneumothorax—Still an Unveiled Disease

  • Iwona Damps-Konstańska,
  • Adriana Szukalska,
  • Piotr Janowiak and
  • Ewa Jassem

9 December 2024

This review presents current opinions on an uncommon condition called catamenial pneumothorax (CP), which is usually associated with thoracic endometriosis syndrome (TES). TES is characterized by the presence of endometriotic lesions in pleura and lu...

  • Case Report
  • Open Access
5 Citations
3,841 Views
6 Pages

A Cluster of Paragonimiasis with Delayed Diagnosis Due to Difficulty Distinguishing Symptoms from Post-COVID-19 Respiratory Symptoms: A Report of Five Cases

  • Jun Sasaki,
  • Masanobu Matsuoka,
  • Takashi Kinoshita,
  • Takayuki Horii,
  • Shingo Tsuneyoshi,
  • Daiki Murata,
  • Reiko Takaki,
  • Masaki Tominaga,
  • Mio Tanaka and
  • Tomoaki Hoshino
  • + 2 authors

10 January 2023

Paragonimiasis caused by trematodes belonging to the genus Paragonimus is often accompanied by chronic respiratory symptoms such as cough, the accumulation of sputum, hemoptysis, and chest pain. Prolonged symptoms, including respiratory symptoms, aft...

  • Case Report
  • Open Access
2 Citations
3,296 Views
14 Pages

Multisystemic Beryllium Disease: An Exceptional Case Revealed by a Urinary Tract Granulomatosis

  • Lucas Jacobs,
  • Maxime Taghavi,
  • Jennifer Fallas,
  • Caroline Geers,
  • Mark Libertalis,
  • Julie Smet,
  • Joëlle Nortier and
  • Maria do Carmo Filomena Mesquita

Chronic beryllium disease (CBD), or berylliosis, is an interstitial lung disease caused by the chronic inhalation of finely particulate beryllium, frequently mistaken for sarcoidosis. It is rarely associated with skin nodular lesions, asymptomatic gr...

  • Article
  • Open Access
17 Citations
1,219 Views
9 Pages

30 April 2014

Introduction: The available data on the epidemiology of interstitial lung disease (ILD) from India is sparse. Hence, the present study was undertaken with the aim to analyse the demographic profile and clinical, radiological and pathological characte...

  • Article
  • Open Access
5 Citations
1,201 Views
6 Pages

Papillary Thyroid Carcinoma in a Boy with Familial Tuberous Sclerosis Complex Attributable to a TSC2 Deletion—A Case Report

  • M. Flader,
  • P. Kurzawa,
  • J. Maldyk,
  • J. Sygut,
  • J. Harasymczuk,
  • A. Kropinska,
  • D. Handkiewicz-Junak,
  • B. Jarzab,
  • K. Kotulska and
  • M. Niedziela

1 October 2017

Tuberous sclerosis complex (TSC), a phacomatosis, is a rare genetic disease (autosomal dominant; incidence: 1 in 6,800–17,300) associated with mutations in the TSC1 and TSC2 genes, 70% of which are sporadic. The disease causes benign tumours in the b...

  • Case Report
  • Open Access
7 Citations
3,166 Views
11 Pages

Severe Fatal Mucormycosis in a Patient with Chronic Lymphocytic Leukaemia Treated with Zanubrutinib: A Case Report and Review of the Literature

  • Giuseppe Maggioni,
  • Marny Fedrigo,
  • Andrea Visentin,
  • Elisa Carturan,
  • Valeria Ruocco,
  • Livio Trentin,
  • Mauro Alaibac and
  • Annalisa Angelini

7 September 2023

Severe mucormycosis is a fatal disease rarely complicating chronic lymphoproliferative disorders. We present a fulminant and fatal case of a 74-year-old Caucasian woman suffering from CLL treated with second-generation BTK inhibitor zanubrutinib. Aft...

  • Article
  • Open Access
2 Citations
2,347 Views
12 Pages

Possible Role of Chest Ultrasound in the Assessment of Costo-Phrenic Angle Lesions Prior to Medical Thoracoscopy: A Retrospective Pilot Case Series

  • Emanuele Giovanni Conte,
  • Andrea Smargiassi,
  • Filippo Lococo,
  • Giampietro Marchetti and
  • Riccardo Inchingolo

25 October 2022

Background: Pleural malignancy (PM) and malignant pleural effusion (MPE) represent an increasing burden of diseases. Costo-phrenic angle (CPA) could be involved by malignant small nodularities or thickenings in the case of MPE. The aim of this study...

  • Case Report
  • Open Access
3 Citations
3,470 Views
9 Pages

13 November 2021

Sarcoidosis is a multisystem disease usually affecting the chest, hilar lymph nodes, and lungs, but can potentially involve any organ; therefore, its clinical presentation may vary. Hepatobiliary involvement is rare, and typically asymptomatic; howev...

  • Case Report
  • Open Access
656 Views
6 Pages

Lymphomatoid Granulomatosis and Tuberculosis, Coincidence or Cohabitation—A Case Report

  • Nicolas Giachetti,
  • Sarah Bellal,
  • Marianne Schwarz,
  • Jérôme Paillassa,
  • Aline Clavert,
  • Mathilde Hunault-Berger and
  • Firas Safa

15 September 2025

Background: Lymphomatoid granulomatosis (LYG) is a rare and atypical EBV-induced B-cell lymphoproliferative disorder. Clinical manifestations are mainly respiratory, with nodular infiltrates, varying in number and size, being responsible for respirat...

  • Review
  • Open Access
1,755 Views
15 Pages

The Role of [18F]FDG PET Imaging for the Assessment of Pulmonary Lymphangitic Carcinomatosis: A Comprehensive Narrative Literature Review

  • Francesco Dondi,
  • Pietro Bellini,
  • Michela Cossandi,
  • Luca Camoni,
  • Roberto Rinaldi,
  • Gian Luca Viganò and
  • Francesco Bertagna

Background/Objectives: Pulmonary lymphangitic carcinomatosis (PLC) is a rare, aggressive manifestation of metastatic cancer characterized by lymphatic infiltration of the lungs, typically indicating advanced disease and poor prognosis. Methods: This...

  • Article
  • Open Access
5 Citations
4,825 Views
14 Pages

Epidemiological, Pathological, and Molecular Studies on Sheeppox Disease Outbreaks in Karnataka, India

  • Gundallahalli Bayyappa Manjunatha Reddy,
  • Varun Kumar Krishnappa,
  • Chandan Dypasandra Siddalingaiah,
  • Suguna Rao,
  • Shivasharanappa Nayakvadi,
  • Chethan Kumar Harlipura Basavarajappa and
  • Baldev Raj Gualti

An epidemiological study spanning twelve years has revealed that sheeppox disease is both widespread and endemic, predominantly surging during the winter and summer seasons. This investigation focused on sheeppox across 11 field outbreaks, involving...