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28 Results Found

  • Article
  • Open Access
12 Citations
6,164 Views
14 Pages

Antibacterial Effect of a 4x Cu-TiO2 Coating Simulating Acute Periprosthetic Infection—An Animal Model

  • Andreas Mauerer,
  • Stefanie Stenglein,
  • Stefan Schulz-Drost,
  • Christoph Schoerner,
  • Dominic Taylor,
  • Sebastian Krinner,
  • Frank Heidenau,
  • Werner Adler and
  • Raimund Forst

The purpose of our study was to investigate the antibacterial effect of a spacer (Ti6Al4V) coated with 4x Cu-TiO2 in an animal model simulating an acute periprosthetic infection by Staphylococcus aureus. Ti6Al4 bolts contaminated with Staphylococcus ...

  • Article
  • Open Access
2,265 Views
23 Pages

Coupling APS/SPS Techniques for Cu-TiO2 Antibacterial Coating Deposition: Application to Water Treatment

  • Laurène Youssef,
  • Audrey Prorot,
  • Laurène Gnodé,
  • Pierre Th’Madiou Verdieu,
  • Armelle Vardelle,
  • Vincent Rat and
  • Alain Denoirjean

9 November 2024

Since the COVID-19 pandemic, efforts in the field of surface decontamination have been redoubled. Finding innovative self-cleaning devices has become a challenge, and several solutions have been proposed in the market in recent years. In this work, a...

  • Article
  • Open Access
962 Views
36 Pages

Multilayer Ti–Cu Oxide Coatings on Ti6Al4V: Balancing Antibacterial Activity, Mechanical Strength, Corrosion Resistance, and Cytocompatibility

  • Stefan Valkov,
  • Maria P. Nikolova,
  • Tanya V. Dimitrova,
  • Maria Elena Stancheva,
  • Dimitar Dechev,
  • Nikolay Ivanov,
  • Yordan Handzhiyski,
  • Andreana Andreeva,
  • Maria Ormanova and
  • Margarita D. Apostolova
  • + 1 author

Titanium alloys are widely used for biomedical implants, but their performance is limited by wear, corrosion, and susceptibility to bacterial colonisation. To overcome these drawbacks, multilayer Ti–Cu oxide coatings were deposited on Ti6Al4V s...

  • Article
  • Open Access
7 Citations
2,150 Views
25 Pages

Effect of Co-Sputtered Copper and Titanium Oxide Coatings on Bacterial Resistance and Cytocompatibility of Osteoblast Cells

  • Maria P. Nikolova,
  • Iliyan Tzvetkov,
  • Tanya V. Dimitrova,
  • Veronika L. Ivanova,
  • Yordan Handzhiyski,
  • Andreana Andreeva,
  • Stefan Valkov,
  • Maria Ormanova and
  • Margarita D. Apostolova

4 July 2024

One of the primary risk factors for implant failure is thought to be implant-related infections during the early healing phase. Developing coatings with cell stimulatory behaviour and bacterial adhesion control is still difficult for bone implants. T...

  • Article
  • Open Access
2 Citations
2,020 Views
17 Pages

One-Step Magneton Sputtering of Crystalline Cu-Doped TiO2 Coatings: Characterization and Antibacterial Activity

  • Maria P. Nikolova,
  • Sadegh Yousefi,
  • Yordan Handzhiyski and
  • Margarita D. Apostolova

21 October 2024

Early biofilm formation could be inhibited by applying a thin biocompatible copper coating to reduce periprosthetic infections. In this study, we deposited crystalline Cu-doped TiO2 films using one-step DC magnetron sputtering in an oxygen atmosphere...

  • Article
  • Open Access
60 Citations
7,494 Views
10 Pages

27 August 2018

Cu-doped titanium dioxide thin films (Cu/TiO2) were prepared on glass substrate via peroxo sol-gel method and dip-coating process with no subsequent calcination process for the degradation of organic dye and use as an antibacterial agent. The as-prep...

  • Feature Paper
  • Article
  • Open Access
239 Citations
19,380 Views
20 Pages

Cu-Doped TiO2: Visible Light Assisted Photocatalytic Antimicrobial Activity

  • Snehamol Mathew,
  • Priyanka Ganguly,
  • Stephen Rhatigan,
  • Vignesh Kumaravel,
  • Ciara Byrne,
  • Steven J. Hinder,
  • John Bartlett,
  • Michael Nolan and
  • Suresh C. Pillai

26 October 2018

Surface contamination by microbes is a major public health concern. A damp environment is one of potential sources for microbe proliferation. Smart photocatalytic coatings on building surfaces using semiconductors like titania (TiO2) can effectively...

  • Article
  • Open Access
16 Citations
3,966 Views
19 Pages

The Preparation and Properties of Multilayer Cu-MTa2O5 Composite Coatings on Ti6Al4V for Biomedical Applications

  • Zeliang Ding,
  • Yi Wang,
  • Quan Zhou,
  • Ziyu Ding,
  • Yiyong Wu,
  • Yuefang Zhu,
  • Wensong Shi and
  • Quanguo He

21 October 2019

For the enhancement of the anticorrosion and antibacterial performance of the biomedical alloy Ti6Al4V, a novel Cu incorporated multilayer Ta2O5ceramic composite coating Cu-Ta2O5/Ta2O5/Ta2O5-TiO2/TiO2/Ti (coating codeCu-MTa2O5) was developed by radio...

  • Article
  • Open Access
28 Citations
3,592 Views
16 Pages

31 December 2019

Bacterial infection and toxic metal ions releasing are the challenges in the clinical application of Ti6Al4V alloy implant materials. Copper is a kind of long-acting, broad-spectrum and safe antibacterial element, and Ta2O5 has good corrosion resista...

  • Article
  • Open Access
37 Citations
5,636 Views
19 Pages

20 December 2018

The bioactive and anti-bacterial Cu-based bioceramic TiO2 coatings have been fabricated on cp-Ti (Grade 2) by two-steps. These two-steps combine micro-arc oxidation (MAO) and physical vapor deposition–thermal evaporation (PVD-TE) techniques for...

  • Article
  • Open Access
13 Citations
2,907 Views
18 Pages

Effect of TiO2 Concentration on Microstructure and Properties of Composite Cu–Sn–TiO2 Coatings Obtained by Electrodeposition

  • Aliaksandr A. Kasach,
  • Dzmitry S. Kharytonau,
  • Andrei V. Paspelau,
  • Jacek Ryl,
  • Denis S. Sergievich,
  • Ivan M. Zharskii and
  • Irina I. Kurilo

18 October 2021

In this work, Cu–Sn–TiO2 composite coatings were electrochemically obtained from a sulfate bath containing 0–10 g/L of TiO2 nanoparticles. The effect of TiO2 particles on kinetics of cathodic electrodeposition has been studied by linear sweep voltamm...

  • Article
  • Open Access
23 Citations
6,199 Views
17 Pages

The Effects of Cu-doped TiO2 Thin Films on Hyperplasia, Inflammation and Bacteria Infection

  • Linhua Li,
  • Ying Xu,
  • Zhi Zhou,
  • Jiang Chen,
  • Ping Yang,
  • Youhe Yang,
  • Jing’an Li and
  • Nan Huang

3 November 2015

In the present work, different concentrations of Cu ion (1, 2, 5 and 10 wt %) were doped in the TiO2 film by a sol-gel method and dip coating process. The morphology of the Cu-doped TiO2 films were characterized by scanning electron microscopy (SEM)...

  • Review
  • Open Access
24 Citations
4,362 Views
38 Pages

Atomic Layer Deposition of Antibacterial Nanocoatings: A Review

  • Denis Nazarov,
  • Lada Kozlova,
  • Elizaveta Rogacheva,
  • Ludmila Kraeva and
  • Maxim Maximov

24 November 2023

In recent years, antibacterial coatings have become an important approach in the global fight against bacterial pathogens. Developments in materials science, chemistry, and biochemistry have led to a plethora of materials and chemical compounds that...

  • Article
  • Open Access
13 Citations
3,239 Views
15 Pages

Influence of Deposition Parameters of TiO2 + CuO Coating on the Membranes Surface Used in the Filtration Process of Dairy Wastewater on Their Functional Properties

  • Joanna Kacprzyńska-Gołacka,
  • Monika Łożyńska,
  • Wioletta Barszcz,
  • Sylwia Sowa,
  • Piotr Wieciński,
  • Ewa Woskowicz and
  • Maciej Życki

A novel approach of the deposition of two-component coating consisting of TiO2 and CuO on polymer membranes by MS-PVD method was presented in this work. This confirmed the possibility of using thin functional coatings for the modification of polymer...

  • Feature Paper
  • Article
  • Open Access
533 Views
18 Pages

Biological Response and Antimicrobial Behaviour of Sputtered TiO2/Cu Coatings Deposited on Ti6Al4V Alloy

  • Maria P. Nikolova,
  • Yordan Handzhiyski,
  • Tanya V. Dimitrova,
  • Andreana Andreeva,
  • Stefan Valkov,
  • Maria Ormanova and
  • Margarita D. Apostolova

18 November 2025

Nanostructured TiO2/Cu coatings were deposited on Ti6Al4V alloy by a two-step glow-discharge sputtering process and evaluated for their structural, electrochemical, and biological properties. Dual-acid etching produced microroughened substrates befor...

  • Article
  • Open Access
5 Citations
2,129 Views
21 Pages

Polydopamine-Coated Copper-Doped Co3O4 Nanosheets Rich in Oxygen Vacancy on Titanium and Multimodal Synergistic Antibacterial Study

  • Jinteng Qi,
  • Miao Yu,
  • Yi Liu,
  • Junting Zhang,
  • Xinyi Li,
  • Zhuo Ma,
  • Tiedong Sun,
  • Shaoqin Liu and
  • Yunfeng Qiu

26 April 2024

Medical titanium-based (Ti-based) implants in the human body are prone to infection by pathogenic bacteria, leading to implantation failure. Constructing antibacterial nanocoatings on Ti-based implants is one of the most effective strategies to solve...

  • Article
  • Open Access
5 Citations
2,480 Views
13 Pages

3 December 2022

In this paper, MAO-Cu/Cu-(HEA)N composite coatings on TC4 titanium alloy were prepared by combining micro arc oxidation (MAO) with magnetron sputtering (MS) to enhance the wear resistance and antibacterial ability of the substrate in simulated seawat...

  • Article
  • Open Access
9 Citations
3,305 Views
24 Pages

16 August 2023

Literature reviews have described the applications of silver, copper, and zinc ions and metallic particles of Cu, Ti, and Zn oxides, which have been found to be useful antimicrobial reagents for the biofunctionalization of various materials and their...

  • Article
  • Open Access
3 Citations
1,785 Views
19 Pages

Polyol Formation of Silver@Metal Oxides Nanohybrid for Photocatalytic and Antibacterial Performance

  • Jovairya Azam,
  • Zahoor Ahmad,
  • Ali Irfan,
  • Asima Naz,
  • Muhammad Arshad,
  • Rabia Sattar,
  • Mohammad Raish,
  • Bakar Bin Khatab Abbasi and
  • Yousef A. Bin Jardan

17 March 2025

The polyol method under a single pot has successfully produced a coating of CuO, TiO2, and the combination of CuO/TiO2 around Ag NWs under sequential addition. The Ag NWs and their coating with a pure metal oxide and a hybrid of metal oxide were char...

  • Article
  • Open Access
9 Citations
2,822 Views
18 Pages

Antimicrobial Properties of TiO2 Microparticles Coated with Ca- and Cu-Based Composite Layers

  • Razvan Bucuresteanu,
  • Monica Ionita,
  • Viorel Chihaia,
  • Anton Ficai,
  • Roxana-Doina Trusca,
  • Cornelia-Ioana Ilie,
  • Andrei Kuncser,
  • Alina-Maria Holban,
  • Grigore Mihaescu and
  • Lia-Mara Ditu
  • + 5 authors

The ability of TiO2 to generate reactive oxygen species under UV radiation makes it an efficient candidate in antimicrobial studies. In this context, the preparation of TiO2 microparticles coated with Ca- and Cu-based composite layers over which Cu(I...

  • Article
  • Open Access
7 Citations
3,236 Views
18 Pages

Metal Ions Supported Porous Coatings by Using AC Plasma Electrolytic Oxidation Processing

  • Krzysztof Rokosz,
  • Tadeusz Hryniewicz,
  • Steinar Raaen,
  • Sofia Gaiaschi,
  • Patrick Chapon,
  • Dalibor Matýsek,
  • Kornel Pietrzak,
  • Monika Szymańska and
  • Łukasz Dudek

31 August 2020

Coatings enriched with zinc and copper as well as calcium or magnesium, fabricated on titanium substrate by Plasma Electrolytic Oxidation (PEO) under AC conditions (two cathodic voltages, i.e., −35 or −135 V, and anodic voltage of +400 V)...

  • Feature Paper
  • Article
  • Open Access
31 Citations
4,314 Views
19 Pages

The Beneficial Mechanical and Biological Outcomes of Thin Copper-Gallium Doped Silica-Rich Bio-Active Glass Implant-Type Coatings

  • George E. Stan,
  • Teddy Tite,
  • Adrian-Claudiu Popa,
  • Iuliana Maria Chirica,
  • Catalin C. Negrila,
  • Cristina Besleaga,
  • Irina Zgura,
  • Any Cristina Sergentu,
  • Gianina Popescu-Pelin and
  • José M. F. Ferreira
  • + 4 authors

20 November 2020

Silica-based bioactive glasses (SBG) hold great promise as bio-functional coatings of metallic endo-osseous implants, due to their osteoproductive potential, and, in the case of designed formulations, suitable mechanical properties and antibacterial...

  • Article
  • Open Access
3 Citations
2,224 Views
12 Pages

18 December 2023

The protection of implant surfaces from biofilm and corrosion is crucial for osteogenesis and tissue engineering. To this end, an L-glutamine-based green corrosion inhibitor with recently established anticancer properties has been applied onto antiba...

  • Review
  • Open Access
41 Citations
6,185 Views
17 Pages

13 February 2017

Photocatalytic antibacterial sol-gel coated substrates have been reported to kill bacteria under light or in the dark. These coatings showed non-uniform distribution, poor adhesion to the substrate and short effective lifetime as antibacterial surfac...

  • Review
  • Open Access
82 Citations
8,161 Views
23 Pages

Bactericidal and Virucidal Activities of Biogenic Metal-Based Nanoparticles: Advances and Perspectives

  • Gonzalo Tortella,
  • Olga Rubilar,
  • Paola Fincheira,
  • Joana C. Pieretti,
  • Paola Duran,
  • Isabella M. Lourenço and
  • Amedea B. Seabra

Much progress has been achieved in the preparation and application of engineered nanoparticles (NPs) in the field of medicine, mainly for antibacterial and antiviral applications. In the war against bacteria and viruses, besides traditional antibioti...

  • Article
  • Open Access
16 Citations
3,426 Views
19 Pages

Mechanical Behavior of Bi-Layer and Dispersion Coatings Composed of Several Nanostructures on Ti13Nb13Zr Alloy

  • Dorota Rogala-Wielgus,
  • Beata Majkowska-Marzec,
  • Andrzej Zieliński,
  • Michał Bartmański and
  • Bartosz Bartosewicz

28 May 2021

Titanium implants are commonly used because of several advantages, but their surface modification is necessary to enhance bioactivity. Recently, their surface coatings were developed to induce local antibacterial properties. The aim of this research...

  • Article
  • Open Access
2,664 Views
29 Pages

In Vitro Antibacterial Efficacy of a New TiO2-Cu-Coated Titanium Surface for Biomedical Applications

  • Mahalakshmi Pandian,
  • Sacha Cavelier,
  • Simone Guttau,
  • Silvia Cometta,
  • Joseph Fernando,
  • Philipp Kobbe and
  • Dietmar W. Hutmacher

19 November 2025

Despite advancements in surgical care, the management of surgical site infections (SSIs) associated with fracture-fixation devices is still a challenge after implant fixation, especially in open fractures. Staphylococcus aureus (S. aureus) is a commo...

  • Review
  • Open Access
31 Citations
6,262 Views
26 Pages

1 November 2019

Thermosetting polymers derived from vegetable oils (VOs) exhibit a wide range of outstanding properties that make them suitable for coatings, paints, adhesives, food packaging, and other industrial appliances. In addition, some of them show remarkabl...