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20 Results Found

  • Review
  • Open Access
78 Citations
25,921 Views
15 Pages

13 January 2020

Oxidative stress, caused by the overproduction of free radicals, leads to the development of many chronic diseases including cancer. Free radicals are known to damage cellular biomolecules like lipids, proteins, and DNA that results in activation of...

  • Article
  • Open Access
12 Citations
4,295 Views
18 Pages

Triphala in Traditional Ayurvedic Medicine Inhibits Dengue Virus Infection in Huh7 Hepatoma Cells

  • Aussara Panya,
  • Kanyaluck Jantakee,
  • Suthida Punwong,
  • Supawadee Thongyim,
  • Thida Kaewkod,
  • Pa-thai Yenchitsomanus,
  • Yingmanee Tragoolpua and
  • Hataichanok Pandith

28 November 2021

Traditional Triphala (three fruits), consisting of Phyllanthus emblica, Terminalia chebula, and Terminalia bellirica, presents a broad range of biological activities. However, its ability to inhibit dengue virus (DENV) infection has not been reported...

  • Review
  • Open Access
5,628 Views
11 Pages

Efficacy of Triphala and Chlorhexidine Mouthwashes on Gingival Inflammation and Dental Plaque in Children: A Systematic Review

  • Anuja Singaraju,
  • Sivakumar Nuvvula,
  • Venkata Ratna Kumar Rudravaram,
  • Karthik Anchala,
  • Kanamarlapudi Venkata Saikiran and
  • Sreekanth Kumar Mallineni

18 November 2024

Aim: The aim of this study was to evaluate and compare the efficacy of Triphala and chlorhexidine mouthwashes in reducing gingivitis and dental plaque in children. Methodology: A literature search was confined to the English language using MeSH terms...

  • Article
  • Open Access
6 Citations
4,991 Views
16 Pages

6 October 2024

Obesity, characterized by the excessive accumulation of fat, is a prevalent metabolic disorder that poses a significant global health concern. Triphala, an herbal combination consisting of Phyllanthus emblica Linn, Terminalia chebula Retz, and Termin...

  • Article
  • Open Access
19 Citations
4,666 Views
15 Pages

Safety of the Oral Triphala Recipe from Acute and Chronic Toxicity Tests in Sprague-Dawley Rats

  • Warangkana Arpornchayanon,
  • Subhawat Subhawa,
  • Kanjana Jaijoy,
  • Nirush Lertprasertsuk,
  • Noppamas Soonthornchareonnon and
  • Seewaboon Sireeratawong

30 August 2022

Background: The Indian Ayurvedic herbal formula Triphala (TPL) is known for its pharmacological properties for immunomodulation, anti-inflammation, antioxidant, and anti-cancer. This study aimed to investigate the acute and chronic toxicities of the...

  • Article
  • Open Access
8 Citations
7,193 Views
10 Pages

8 January 2022

As the human lifespan becomes longer, many people invest time and money in managing external beauty. However, managing external beauty has the disadvantage of causing side effects or that the effect does not last. Therefore, research and development...

  • Article
  • Open Access
2 Citations
3,149 Views
16 Pages

Safety Evaluation for Acute and Chronic Oral Toxicity of Maha Pigut Triphala Contains Three Medicinal Fruits in Sprague-Dawley Rats

  • Supaporn Intatham,
  • Weerakit Taychaworaditsakul,
  • Parirat Khonsung,
  • Sunee Chansakaow,
  • Kanjana Jaijoy,
  • Nirush Lertprasertsuke,
  • Noppamas Soonthornchareonnon and
  • Seewaboon Sireeratawong

2 December 2024

Maha Pigut Triphala is the herbal mixture of three fruits consisting of T. bellirica, T. chebula, and E. officinalis also known as P. emblica. Humans regularly eat the fresh fruits of these plants on a daily basis. Maha Pigut Triphala is one of the w...

  • Article
  • Open Access
17 Citations
4,410 Views
16 Pages

Multiple Targets Directed Multiple Ligands: An In Silico and In Vitro Approach to Evaluating the Effect of Triphala on Angiogenesis

  • Chandran S. Abhinand,
  • Prabhakaran A. Athira,
  • Sasikumar J. Soumya and
  • Perumana R. Sudhakaran

23 January 2020

Angiogenesis is critical in both physiological and pathological conditions and targeting angiogenesis is a promising strategy for the development of therapies against cancer; however, cells develop resistance to anti-angiogenic therapy, necessitating...

  • Article
  • Open Access
1 Citations
2,075 Views
18 Pages

Anti-Inflammatory and Antioxidant Effects of HIIT in Individuals with Long COVID: Insights into the Potential Role of Triphala

  • Tadsawiya Padkao,
  • Suwipa Intakhiao,
  • Nattaphol Prakobkaew,
  • Surachat Buddhisa,
  • Yothin Teethaisong,
  • Orachorn Boonla and
  • Piyapong Prasertsri

4 September 2025

Long COVID is characterized by persistent symptoms associated with chronic inflammation and oxidative stress. While high-intensity interval training (HIIT) and supplementation with antioxidants such as Triphala have demonstrated individual therapeuti...

  • Article
  • Open Access
8 Citations
2,770 Views
25 Pages

Inhibition of SARS-CoV-2-Induced NLRP3 Inflammasome-Mediated Lung Cell Inflammation by Triphala-Loaded Nanoparticle Targeting Spike Glycoprotein S1

  • Chuda Chittasupho,
  • Sonthaya Umsumarng,
  • Kamonwan Srisawad,
  • Punnida Arjsri,
  • Rungsinee Phongpradist,
  • Weerasak Samee,
  • Wipawan Tingya,
  • Chadarat Ampasavate and
  • Pornngarm Dejkriengkraikul

The COVID-19 pandemic, caused by SARS-CoV-2, poses a significant global health threat. The spike glycoprotein S1 of the SARS-CoV-2 virus is known to induce the production of pro-inflammatory mediators, contributing to hyperinflammation in COVID-19 pa...

  • Proceeding Paper
  • Open Access
2 Citations
9,636 Views
5 Pages

Formulation Development of a Patient Friendly Dosage Form for Eye Drug Delivery: Kajal

  • Sandeep Waghulde,
  • Archana Pawar,
  • Minal Kadav,
  • Pratiksha Khade,
  • Mohan Kale,
  • Bharat Tekade,
  • Nilesh Gorde and
  • Pravin Naik

14 November 2018

Traditionally, kajal is known as kohl or surma and is used as eyeliner. Designing herbal kajal with medicinal plants as a cosmetics product is considered to bea novel, innovative technique. The main advantages of such a product are that it is patient...

  • Review
  • Open Access
190 Citations
43,788 Views
19 Pages

Neuroprotective Herbs for the Management of Alzheimer’s Disease

  • Julie Gregory,
  • Yasaswi V. Vengalasetti,
  • Dale E. Bredesen and
  • Rammohan V. Rao

8 April 2021

Background—Alzheimer’s disease (AD) is a multifactorial, progressive, neurodegenerative disease that is characterized by memory loss, personality changes, and a decline in cognitive function. While the exact cause of AD is still unclear, recent studi...

  • Article
  • Open Access
3 Citations
3,185 Views
26 Pages

Investigation of a Thermoresponsive In Situ Hydrogel Loaded with Nanotriphala: Implications for Antioxidant, Anti-Inflammatory, and Antimicrobial Therapy in Nasal Disorders

  • Rungsinee Phongpradist,
  • Chuda Chittasupho,
  • Sudarshan Singh,
  • Julalak Chorachoo Ontong,
  • Sarin Tadtong,
  • Puriputt Akachaipaibul,
  • Charatda Punvittayagul,
  • Kriangkrai Thongkorn,
  • Pornngarm Dejkriengkraikul and
  • Darunee Hongwiset
  • + 2 authors

2 February 2025

Oxidative stress plays a crucial role in chronic nasal disorders, contributing to inflammation, tissue damage, and impaired mucosal function, highlighting the need for targeted therapies. Recent advancements in nasal drug delivery systems have expand...

  • Article
  • Open Access
67 Citations
10,610 Views
22 Pages

13 October 2015

Chebulic ellagitannins (ChET) are plant-derived polyphenols containing chebulic acid subunits, possessing a wide spectrum of biological activities that might contribute to health benefits in humans. The herbal formulation Padma Hepaten containing ChE...

  • Article
  • Open Access
9 Citations
4,133 Views
26 Pages

Antiplasmodial Properties of Aqueous and Ethanolic Extracts of Ten Herbal Traditional Recipes Used in Thailand against Plasmodium falciparum

  • Arisara Phuwajaroanpong,
  • Prapaporn Chaniad,
  • Walaiporn Plirat,
  • Sathianpong Phoopha,
  • Abdi Wira Septama,
  • Arnon Chukaew and
  • Chuchard Punsawad

This study evaluated the in vitro and in vivo antiplasmodial efficacy and toxicity of aqueous and ethanolic extracts from traditional recipes used in Thailand. The aqueous and ethanolic extracts of ten traditional recipes were tested for in vitro ant...

  • Review
  • Open Access
12 Citations
3,894 Views
12 Pages

A Narrative Review of the Herbal Preparation of Ayurvedic, Traditional Chinese, and Kampō Medicines Applied as Radioprotectors

  • Blanca Ibáñez,
  • Ana Melero,
  • Alegría Montoro,
  • Juan F. Merino-Torres,
  • Jose M. Soriano and
  • Nadia San Onofre

In recent years, there has been growing scientific interest in the search for natural radioprotectors that can be used to mitigate the effects of radiation on patients, healthcare personnel, and even for space travel. This narrative review covers the...

  • Article
  • Open Access
54 Citations
5,695 Views
14 Pages

Natural Nitrogen-Doped Carbon Dots Obtained from Hydrothermal Carbonization of Chebulic Myrobalan and Their Sensing Ability toward Heavy Metal Ions

  • Raji Atchudan,
  • Suguna Perumal,
  • Thomas Nesakumar Jebakumar Immanuel Edison,
  • Ashok K. Sundramoorthy,
  • Rajangam Vinodh,
  • Sambasivam Sangaraju,
  • Somasundaram Chandra Kishore and
  • Yong Rok Lee

10 January 2023

Chebulic Myrobalan is the main ingredient in the Ayurvedic formulation Triphala, which is used for kidney and liver dysfunctions. Herein, natural nitrogen-doped carbon dots (NN-CDs) were prepared from the hydrothermal carbonization of Chebulic Myroba...

  • Article
  • Open Access
1,807 Views
21 Pages

Myrobalan Fruit Extracts Modulate Immunobiochemical Pathways In Vitro

  • Stefanie Hofer,
  • Marcel Jenny,
  • Angela Klein,
  • Kathrin Becker,
  • Lucia Parráková,
  • Florian Überall,
  • Markus Ganzera,
  • Dietmar Fuchs,
  • Hubert Hackl and
  • Johanna M. Gostner
  • + 1 author

Myrobalan fruits are important ingredients of traditional remedies, such as the Ayurvedic formulation Triphala or the Tibetan formulation Bras bu 3. Myrobalan-containing remedies are described to have positive effects on metabolism, the cardiovascula...

  • Systematic Review
  • Open Access
447 Views
21 Pages

Comparison Between Natural Products and Chlorhexidine in Non-Surgical Periodontal Therapy: A Systematic Review of Randomized Clinical Trials

  • Andrea Scribante,
  • Matteo Pellegrini,
  • Maurizio Pascadopoli,
  • Valentino Natoli,
  • Valentina Poma and
  • Andrea Butera

13 February 2026

Objectives: To evaluate the clinical effectiveness and safety of natural products compared with chlorhexidine (CHX) as adjuncts to non-surgical periodontal therapy (NSPT) in patients with periodontitis. Materials and Methods: This systematic review w...

  • Article
  • Open Access
8 Citations
2,549 Views
13 Pages

26 August 2022

The objective of this study was to determine the effect of autochthonous Nepalese fruits on nutrient degradation, fermentation kinetics, total gas production, and methane production in in-vitro rumen fermentation. The fruits of Terminalia chebul...