28 Results Found

Objectives: One dose of Sabin-strains inactivated polio vaccine (IPV) was introduced into the Chinese immunization program on 1 May 2016. This study aimed to evaluate the safety of Sabin-strains IPV and provide a comparison with conventional Salk-str...

The grand challenges of our time—climate change, biodiversity losses, and global non-communicable disease rates—underscore that humanity and the planet are in crisis. Planetary health provides a unifying concept wherein efforts toward rem...

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Rhizosphere colonization by phytobeneficial Pseudomonas spp. is pivotal in triggering their positive effects on plant health. Many Pseudomonas spp. Determinants, involved in rhizosphere colonization, have already been deciphered. However, few studies...

In this work, we have investigated the influence of the transfer process on the monocrystalline graphene in terms of quality, morphology and electrical properties by analyzing the data obtained from optical microscopy, scanning electron microscopy, R...

This paper presents the first graphene radiofrequency (RF) monolithic integrated balun circuit. It is composed of four integrated graphene field effect transistors (GFETs). This innovative active balun concept takes advantage of the GFET ambipolar be...

Accuracy assessment, also referred to as validation, is a key process in the workflow of developing a land cover map. To make this process open and transparent, we have developed a new online tool called LACO-Wiki, which encapsulates this process int...

Measurements of skin surface biomarkers have enormous value for the detailed assessment of skin conditions, both for clinical application and in skin care. The main goals of the current study were to assess whether expression patterns of skin surface...

The idea that closer things are more related than distant things, known as ‘Tobler’s first law of geography’, is fundamental to understanding many spatial processes. If this concept applies to volunteered geographic information (VGI), it could help t...

Most poplar plantations are planted on marginal agricultural land, but poplar plantations also hold the potential for increased profits compared to plantations of other species on non-agricultural, previously forested land. To date, the establishment...

A variety of metrics are commonly employed by map producers and users to assess and compare thematic maps’ quality, but their use and interpretation is inconsistent. This problem is exacerbated by a shortage of tools to allow easy calculation and com...

The concept of planetary health blurs the artificial lines between health at scales of person, place, and planet. It emphasizes the interconnected grand challenges of our time, and underscores the need for integration of biological, psychological, so...

Advances in science have illuminated the role of the “ecological theatre”—the total living environment—in human health. In a rapidly changing epoch known as the anthropocene, microbiome science is identifying functional connections between all life,...

This essay discusses the affect of a group of well-known buildings and one project from antiquity to the recent past: Pantheon, Rome; Hagia Sophia, Istanbul; Leon Battista Alberti’s Sant’Andrea, Mantua; Etienne-Louis Boullée’...

In Arabidopsis, the RING finger-containing E3 ubiquitin ligase HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1 (HOS1) functions as a main regulator of the cold signaling. In this study, CRISPR/Cas9-mediated targeted mutagenesis of the HOS1 gene in...

The aim of this study was to elucidate whether the membrane nanodomain protein AtFlot1 is involved in vesicular transport pathways and regulation of the P-type H⁺-ATPase content in plasma membrane of A. thaliana under salt stress. Transmission electr...

Global polio eradication requires both safe and effective vaccines, and safe production processes. Sabin oral poliomyelitis vaccine (OPV) strains can evolve to virulent viruses and result in poliomyelitis outbreaks, and conventional inactivated polio...

Streptococcus suis (S. suis) is an important swine pathogen and an emerging zoonotic agent worldwide. Serotype 9 is the most prevalent serotype in several European countries but it is relatively rare in China. In this study, through the investigation...

Utah, USA, relies heavily on snowpack for water to sustain its growing population. Scientists and policy makers are exploring and proposing several potential sustainable solutions to improving flow to the Great Salk Lake as it recently has significan...

The target of rapamycin (TOR) protein phosphorylates its downstream effector p70kDa ribosomal protein S6 kinases (S6K1) for ribosome biogenesis and translation initiation in eukaryotes. However, the molecular mechanism of TOR-S6K1-ribosomal protein (...

Four decades ago, several health movements were sprouting in isolation. In 1980, the environmental group Friends of the Earth expanded the World Health Organization definition of health, reminding citizenry that, “health is a state of complete...

Rice is sensitive to salinity at both the seedling and reproductive stages, and it reduces the grain yield from 50 to 100%. In this study, 27 SNP markers significantly associated with 15 QTLs were identified. Three major QTLs were associated with sho...

The physiological function of Arabidopsis thaliana universal stress protein (AtUSP) in plant has remained unclear. Thus, we report here the functional role of the Arabidopsis universal stress protein, AtUSP (At3g53990). To determine how AtUSP affects...

The emerging evidence has shown that plant serine/arginine-rich (SR) proteins play a crucial role in abiotic stress responses by regulating the alternative splicing (AS) of key genes. Recently, we have shown that drought stress enhances the expressio...

The chloroplast comprises the outer and inner membranes that are composed of the translocon protein complexes Toc and Tic (translocon at the outer/inner envelope membrane of chloroplasts), respectively. Tic55, a chloroplast Tic protein member, was sh...

This study reviews the role of epidemiology in the United States in the late 19th and early 20th century, which led to recognition that poliomyelitis is an infectious disease and set the stage for subsequent developments in virology and immunology, t...

Wintersweet (Chimonanthus praecox L.) is an ornamental and economically significant shrub known for its unique flowering characteristics, especially the emission of abundant floral volatile organic compounds. Thus, an understanding of the molecular m...

Background: The previous study assessed the immune durability of the Sabin strain inactivated poliovirus vaccine (sIPV) at four years of age; an update on its long-term persistence is warranted. Methods: This Phase IV, open-label, parallel-controlled...