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29 Results Found

  • Article
  • Open Access
7 Citations
2,862 Views
18 Pages

Microbiome in Lower Urinary Tract Symptoms (LUTSs): Mapping the State of the Art with Bibliometric Analysis

  • Hadi Mostafaei,
  • Hanieh Salehi-Pourmehr,
  • Mohammad Sajjad Rahnama’i,
  • Helia Mostafaei,
  • Shahrokh F. Shariat and
  • Sakineh Hajebrahimi

16 February 2023

Background: The main objective of this study is to provide the first characterization of the current research field of the clinical microbiome in LUTSs. Methods: First-of-its-kind scientometric insight into the historical development and structural s...

  • Systematic Review
  • Open Access
1 Citations
2,106 Views
32 Pages

3 July 2025

Background and Objectives: Sarcopenia and lower urinary tract symptoms (LUTSs) are both prevalent among older adults and may share underlying pathophysiological mechanisms. However, their association has not been systematically quantified. This syste...

  • Case Report
  • Open Access
1 Citations
2,303 Views
12 Pages

Strategies to Improve Bladder Control: A Preliminary Case Study

  • Gesualdo M. Zucco,
  • Elena Andretta and
  • Thomas Hummel

15 September 2024

Background: Lower urinary tract symptoms (LUTSs) are a common complaint in adult and elderly men with bladder outlet obstruction, and have a considerable impact on their quality of life. Symptoms affect storage, voiding and post micturition stages. A...

  • Article
  • Open Access
9 Citations
2,958 Views
23 Pages

Inhibition of α1-Adrenergic, Non-Adrenergic and Neurogenic Human Prostate Smooth Muscle Contraction and of Stromal Cell Growth by the Isoflavones Genistein and Daidzein

  • Ru Huang,
  • Yuhan Liu,
  • Sheng Hu,
  • Alexander Tamalunas,
  • Raphaela Waidelich,
  • Frank Strittmatter,
  • Christian G. Stief and
  • Martin Hennenberg

22 November 2022

Isoflavone-rich legumes, including soy, are used for food production, as dietary supplements and in traditional medicine. Soy consumption correlates negatively with benign prostatic hyperplasia (BPH) and voiding symptoms. However, isoflavone effects...

  • Article
  • Open Access
6 Citations
3,463 Views
19 Pages

The β3-adrenoceptor agonist mirabegron is available for the treatment of storage symptoms of overactive bladder, including frequency, urgency, and incontinence. The off-target effects of mirabegron include binding to α1-adrenoceptors, whic...

  • Review
  • Open Access
1 Citations
2,736 Views
14 Pages

28 November 2024

Non-muscle invasive bladder cancer (NMIBC) accounts for approximately 70–75% of all bladder cancer cases. The standard treatment for high-risk NMIBC involves transurethral tumour resection followed by intravesical Bacillus Calmette–Guerin...

  • Brief Report
  • Open Access
1,492 Views
7 Pages

Correlation between Higher Aging Males’ Symptoms Scores and a Higher Risk of Lower Urinary Tract Symptoms

  • Takashi Kawahara,
  • Sahoko Ninomiya,
  • Teppei Takeshima,
  • Tomoki Saito,
  • Hiroki Ito,
  • Mitsuru Komeya,
  • Hisashi Hasumi,
  • Yasushi Yumura,
  • Kazuhide Makiyama and
  • Hiroji Uemura

6 December 2023

Background: Late-onset hypogonadism (LOH) is a condition caused by the decline of testosterone levels with aging and is associated with various symptoms, including lower urinary tract symptoms (LUTSs). Although some reports have shown that testostero...

  • Article
  • Open Access
1 Citations
2,496 Views
11 Pages

Prophylactic A-Blockers for Radiotherapy-Induced Lower Urinary Tract Symptoms in Men with Prostate Cancer: A Phase III Randomized Trial

  • Tamim Niazi,
  • Edmond Kaldany,
  • Steven Tisseverasinghe,
  • Talía Malagón,
  • Boris Bahoric,
  • Victor McPherson,
  • Alexis Rompre-Brodeur and
  • Maurice Anidjar

30 June 2023

Purpose: The present phase III randomized trial assessed the efficacy of prophylactic versus therapeutic α-blockers at improving RI-LUTSs in prostate cancer patients receiving external beam radiotherapy (EBRT). Methods: A total of 148 prostate...

  • Brief Report
  • Open Access
1 Citations
4,122 Views
10 Pages

Psychosocial Factors Associated with Lower Urinary Tract Symptoms One Year Postpartum

  • Shayna D. Cunningham,
  • Rogie Royce Carandang,
  • Lisa M. Boyd,
  • Jessica B. Lewis,
  • Jeannette R. Ickovics and
  • Leslie M. Rickey

Pregnancy carries substantial risk for developing lower urinary tract symptoms (LUTSs), with potential lifelong impacts on bladder health. Little is known about modifiable psychosocial factors that may influence the risk of postpartum LUTSs. We exami...

  • Systematic Review
  • Open Access
2,457 Views
16 Pages

Background and Objectives: Lower urinary tract symptoms (LUTSs) are prevalent among patients with uterine myoma (UM); however, these health issues have not been systematically evaluated. To address this research gap, this systematic review and meta-a...

  • Article
  • Open Access
1 Citations
4,092 Views
11 Pages

Salvia miltiorrhiza Root Extract for Men with Lower Urinary Tract Symptoms: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

  • Dongho Shin,
  • Hyong Woo Moon,
  • Woong Jin Bae,
  • U-Syn Ha,
  • Young Ho Park,
  • Eun Joo Lee,
  • Du Geon Moon and
  • Sae Woong Kim

25 December 2024

Background: The prevalence of urological diseases increases with age, and lower urinary tract symptoms (LUTSs) are the most common problem. Natural compounds with minimal side effects for the improvement in LUTSs are of ongoing interest. Salvia milti...

  • Article
  • Open Access
1 Citations
1,745 Views
13 Pages

Self-Assessment of Lower Urinary Tract Condition in Female Competitive Cyclists

  • Mariola Saulicz,
  • Aleksandra Saulicz and
  • Edward Saulicz

During cycling, prolonged compression by the bicycle saddle on the anatomical structures located in the perineum area occurs. An additional factor that may have a negative impact on organs located in the pelvic area may be a prolonged sitting positio...

  • Article
  • Open Access
10 Citations
10,623 Views
14 Pages

17 April 2024

Benign prostatic hyperplasia (BPH) is the non-malignant enlargement of the prostate, associated with lower urinary tract symptoms (LUTSs). Taraxaci Herba (TH), commonly known as dandelion, has traditionally been utilized in East Asia to treat symptom...

  • Article
  • Open Access
31 Citations
4,594 Views
14 Pages

Prostate Artery Embolization Using N-Butyl Cyanoacrylate Glue for Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia: A Valid Alternative to Microparticles?

  • Romaric Loffroy,
  • Kévin Guillen,
  • Etienne Salet,
  • Clément Marcelin,
  • Pierre-Olivier Comby,
  • Marco Midulla,
  • Nicolas Grenier,
  • Olivier Chevallier and
  • François Petitpierre

17 July 2021

Our goal was to evaluate the feasibility, safety, and short-term outcomes of prostate artery embolization (PAE) with N-butyl cyanoacrylate (NBCA) glue as the only embolic agent in patients with benign prostatic hyperplasia (BPH)-related lower urinary...

  • Article
  • Open Access
7 Citations
2,421 Views
12 Pages

26 September 2022

Many patients with outlet obstruction secondary to prostatic enlargement have lower urinary tract symptoms (LUTSs) and an increased frequency of micturition. The standard treatment is transurethral resection of the prostate (TURP), which alleviates o...

  • Review
  • Open Access
2 Citations
8,238 Views
10 Pages

16 October 2024

Background: Benign prostatic hyperplasia (BPH) is the leading cause of lower urinary tract symptoms (LUTSs) in men, with a histological prevalence that increases significantly with age. While extensive research on BPH has been conducted in high-incom...

  • Case Report
  • Open Access
1 Citations
3,868 Views
14 Pages

Self-Inflicted Foreign Bodies in the Lower Urinary Tract Associated with Sexual Activities—A Case Series

  • Michał Godzisz,
  • Iga Kuliniec,
  • Przemysław Mitura,
  • Grzegorz Młynarczyk,
  • Marek Bar,
  • Paweł Płaza,
  • Damian Sudoł,
  • Marcel Pogoda and
  • Krzysztof Bar

31 March 2025

Foreign bodies in urological patients are commonly found in the lower urinary tract, especially in the bladder and urethra. Items such as pens, pencils, wires, and cables are often inserted for erotic stimulation, typically associated with alcohol in...

  • Article
  • Open Access
3 Citations
3,720 Views
12 Pages

Prostate Artery Embolization (PAE) with Small Beads for the Treatment of Benign Prostatic Hyperplasia (BPH)

  • Genti Xhepa,
  • Lucilla Violetta Sciacqua,
  • Andrea Vanzulli,
  • Andrea Enzo Canì,
  • Velio Ascenti,
  • Alexis Ricoeur,
  • Andrea Antonio Ianniello,
  • Agostino Inzerillo,
  • Paolo Nicotera and
  • Gianpaolo Carrafiello
  • + 2 authors

Benign Prostatic Hyperplasia (BPH) is the most frequent cause of Lower Urinary Tract Symptoms (LUTSs) in elderly populations. Minimally invasive treatments of BPH are safe and effective and are gaining popularity among both professionals and patients...

  • Article
  • Open Access
1 Citations
3,506 Views
16 Pages

The Impact of a Healthy Lifestyle on Lower Urinary Tract Symptoms and Erectile Function: A Prospective Study

  • Riccardo Lombardo,
  • Matteo Romagnoli,
  • Chiara Splendore,
  • Luca Sarcinelli,
  • Beatrice Turchi,
  • Giacomo Gallo,
  • Giorgia Tema,
  • Antonio Franco,
  • Antonio Nacchia and
  • Cosimo De Nunzio
  • + 6 authors

18 January 2025

Background and Objectives: The impact of lifestyle on lower urinary tract symptoms has been deeply evaluated in recent years; however, studies in the young population are missing. The aim of this study is to evaluate the impact of alcohol intake, tob...

  • Article
  • Open Access
1 Citations
4,238 Views
9 Pages

16 July 2024

Background/Objectives: This study aimed to identify the unique characteristics of neurogenic bladders and associated symptoms in patients with cervical or thoracic myelopathy using clinical surveys and urodynamic studies (UDSs). Methods: Patients wit...

  • Article
  • Open Access
4 Citations
2,122 Views
25 Pages

Fabrication and Optimization of a Silodosin In Situ-Forming PLGA Implants for the Treatment of Benign Prostatic Hyperplasia: In Vitro and In Vivo Study

  • Rabab A. Husseini,
  • Tarek M. Ibrahim,
  • Eslam Hamed,
  • Eman Gomaa,
  • Mennatullah M. Faisal,
  • Ghadeer Wan,
  • Manna Amin,
  • Ali M. Alkolaib and
  • Dina M. Abdelnabi

Objectives: Lower urinary tract symptoms (LUTSs) related to benign prostatic hyperplasia (BPH) are common in older men, and alpha-adrenoceptor blockers continue to be a key part of managing these symptoms. This study aimed to formulate injectable pol...

  • Article
  • Open Access
1,151 Views
12 Pages

The Impact of MISTs on Australian BPO Surgical Trends

  • David Armany,
  • Lequang Vo,
  • Kathleen Lockhart,
  • Tania Hossack,
  • David Ende,
  • Simon Bariol,
  • Sriskanthan Baskaranathan and
  • Henry Woo

Background/Objectives: To evaluate the impact of Minimally Invasive Surgical Therapies (MISTs) on Australian trends for surgeries treating lower urinary tract symptoms (LUTSs) caused by benign prostatic obstruction (BPO). The recent adoption of the p...

  • Article
  • Open Access
1,871 Views
11 Pages

Real-World Clinical Outcomes of Transperineal Laser Ablation in BPH: A 12-Month Retrospective Analysis

  • Yusuf Özlülerden,
  • Kürşat Küçüker,
  • Sinan Çelen,
  • Mesut Berkan Duran,
  • Aykut Başer,
  • Ahmet Baki Yagci and
  • Ömer Levent Tuncay

28 August 2025

Background/Objectives: Benign prostatic hyperplasia (BPH) is a prevalent condition in aging men and a major cause of lower urinary tract symptoms (LUTSs). While traditional treatments such as transurethral resection of the prostate (TURP) are effecti...

  • Article
  • Open Access
1,512 Views
14 Pages

Quantification of the Role of Teupol® 25P and Graminex® G96 Compared to Hexanic Extract of Serenoa repens in Patients Affected by Lower Urinary Tract Symptoms During Treatment with Silodosin

  • Yazan Al Salhi,
  • Damiano Graziani,
  • Andrea Fuschi,
  • Fabio Maria Valenzi,
  • Manfredi Bruno Sequi,
  • Paolo Pietro Suraci,
  • Alice Antonioni,
  • Onofrio Antonio Rera,
  • Cosimo De Nunzio and
  • Antonio Luigi Pastore
  • + 10 authors

6 July 2025

Background and Objectives: While α1-blockers like silodosin are the mainstay for treating lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH), combination therapy with phytotherapeutics may provide enhanced symptom con...

  • Article
  • Open Access
717 Views
13 Pages

Factors Associated with Health-Related Quality of Life in Patients with Benign Prostatic Hyperplasia Undergoing Pharmacological Treatment: A Cross-Sectional Study

  • Srđan Govedarica,
  • Aleksandar Rašković,
  • Saša Vojinov,
  • Dragan Grbić,
  • Mladen Popov,
  • Biljana Vučković,
  • Dragan Zečević,
  • David Strilić and
  • Dimitrije Jeremić

18 December 2025

Background and Objectives: Benign prostatic hyperplasia (BPH) and associated lower urinary tract symptoms (LUTSs) can substantially impair health-related quality of life (HRQoL). We examined the relationship between LUTS severity, measured by the Int...

  • Article
  • Open Access
3,574 Views
9 Pages

First Multi-Center, Real-World Study on the Temporary Implantable Nitinol Device (iTIND) for the Management of Lower Urinary Tract Symptoms Related to Benign Prostatic Obstruction

  • Roberto Castellucci,
  • Silvia Secco,
  • Alberto Olivero,
  • Feras Al Jaafari,
  • Sinan Khadhouri,
  • Alessio Faieta,
  • Cosimo De Nunzio,
  • Riccardo Lombardo,
  • Simone Morselli and
  • Luca Cindolo
  • + 1 author

Background/Objectives: Lower urinary tract symptoms (LUTSs) due to benign prostatic obstruction (BPO) represent a common condition affecting aging men. Transurethral resection of the prostate represents the gold standard surgical treatment but is not...

  • Article
  • Open Access
1,632 Views
20 Pages

Alteration of the Expression and Functional Activities of Myosin II Isoforms in Enlarged Hyperplastic Prostates

  • Xiao Wang,
  • Weixiang He,
  • Hui Chen,
  • Rui Yang,
  • Hongmei Su,
  • Michael E. DiSanto and
  • Xinhua Zhang

1 April 2024

Introduction: Benign prostatic hyperplasia (BPH) is a common pathologic process in aging men, and the contraction of the prostatic smooth muscles (SMs) in the stroma plays a vital role in this pathogenesis, leading to lower urinary tract symptoms (LU...

  • Article
  • Open Access
5,711 Views
9 Pages

Comparative Effectiveness and Safety of Finasteride and Dutasteride in the Treatment of Benign Prostatic Hyperplasia: A Real-World Retrospective Study

  • Jarosław Ratajski,
  • Kamil Ciechan,
  • Paweł Jędrzejczyk,
  • Tomasz W. Kaminski,
  • Patryk Uciechowski and
  • Tomasz Ząbkowski

30 October 2025

Background and Objectives: Benign prostatic hyperplasia (BPH) is one of the most common chronic conditions in older men, significantly impairing quality of life (QoL) by causing lower urinary tract symptoms (LUTSs). 5-alpha-reductase inhibitors (5-AR...

  • Review
  • Open Access
246 Views
17 Pages

3 March 2026

Background/Objectives: Lower urinary tract symptoms (LUTSs), particularly nocturia and urgency, often intensify during the menopause transition and may worsen with caffeine intake and cold exposure. This review aims to synthesize evidence relevant to...