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17 Results Found

  • Article
  • Open Access
61 Citations
10,847 Views
16 Pages

Antibacterial Effect of Dental Adhesive Containing Dimethylaminododecyl Methacrylate on the Development of Streptococcus mutans Biofilm

  • Suping Wang,
  • Keke Zhang,
  • Xuedong Zhou,
  • Ning Xu and ,
  • Hockin H. K. Xu,
  • Michael D. Weir,
  • Yang Ge,
  • Shida Wang,
  • Mingyun Li and
  • Lei Cheng
  • + 7 authors+ 2 authors

18 July 2014

Antibacterial bonding agents and composites containing dimethylaminododecyl methacrylate (DMADDM) have been recently developed. The objectives of this study were to investigate the antibacterial effect of novel adhesives containing different mass fra...

(This article belongs to the Special Issue Antimicrobial Polymers)
  • Article
  • Open Access
23 Citations
4,310 Views
17 Pages

The Preventive Effect of A Magnetic Nanoparticle-Modified Root Canal Sealer on Persistent Apical Periodontitis

  • Xiao Guo,
  • Yan Sun,
  • Zheng Wang,
  • Biao Ren and ,
  • Hockin H. K. Xu,
  • Xian Peng,
  • Mingyun Li,
  • Suping Wang,
  • Haohao Wang and
  • Lei Cheng
  • + 9 authors+ 4 authors

28 October 2022

Persistent apical periodontitis is a critical challenge for endodontists. Developing root canal filling materials with continuous antibacterial effects and tightly sealed root canals are essential strategies to avoid the failure of root canal therapy...

(This article belongs to the Special Issue Advances and Challenges in Dental Materials)
  • Article
  • Open Access
13 Citations
3,142 Views
14 Pages

Dimethylaminododecyl Methacrylate-Incorporated Dental Materials Could Be the First Line of Defense against Helicobacter pylori

  • Xi Chen,
  • Tiantian Shan,
  • Biao Ren,
  • Lin Zhang and ,
  • Hockin H. K. Xu,
  • Nanxi Wang,
  • Xuedong Zhou,
  • Hong Li and
  • Lei Cheng
  • + 4 authors+ 0 author

4 September 2023

Oral cavity is an essential reservoir for H. pylori. We aimed to investigate the antibacterial effects of dimethylaminododecyl methacrylate (DMADDM) against H. pylori. Modified giomers were prepared by introducing 0%, 1.25% and 2.5% DMADDM monomers....

(This article belongs to the Special Issue Molecular Advances in Helicobacter pylori Infections and Treatments)
  • Article
  • Open Access
19 Citations
6,041 Views
12 Pages

Novel Cavity Disinfectants Containing Quaternary Ammonium Monomer Dimethylaminododecyl Methacrylate

  • Wen Zhou,
  • Biao Ren,
  • Xuedong Zhou,
  • Hockin H.K. Xu and ,
  • Michael D. Weir,
  • Mingyun Li,
  • Mingye Feng,
  • Jiyao Li,
  • Xin Xu and
  • Lei Cheng
  • + 5 authors+ 0 author

9 August 2016

This study was set to assess the possible benefits of novel cavity disinfectants with 5% dimethylaminododecyl methacrylate (DMADDM); and compare the effectiveness of saliva microbial-aging method with water-aging in measuring the changing of resin–de...

(This article belongs to the Section Biomaterials)
  • Article
  • Open Access
20 Citations
3,534 Views
19 Pages

Novel Dental Low-Shrinkage-Stress Composite with Antibacterial Dimethylaminododecyl Methacrylate Monomer

  • Abdullah Alhussein,
  • Rashed Alsahafi,
  • Xiaohong Wang,
  • Heba Mitwalli and ,
  • Hanan Filemban,
  • Gary D. Hack,
  • Thomas W. Oates,
  • Jirun Sun,
  • Michael D. Weir and
  • Hockin H. K. Xu
  • + 5 authors+ 0 author

Objectives: Current dental resins exhibit polymerization shrinkage causing microleakage, which has the potential to cause recurrent caries. Our objectives were to create and characterize low-shrinkage-stress (LSS) composites with dimethylaminododecyl...

  • Article
  • Open Access
29 Citations
6,225 Views
14 Pages

Heat-Polymerized Resin Containing Dimethylaminododecyl Methacrylate Inhibits Candida albicans Biofilm

  • Hui Chen,
  • Qi Han,
  • Xuedong Zhou,
  • Keke Zhang and ,
  • Suping Wang,
  • Hockin H. K. Xu,
  • Michael D. Weir,
  • Mingye Feng,
  • Mingyun Li and
  • Lei Cheng
  • + 7 authors+ 2 authors

20 April 2017

The prevalence of stomatitis, especially caused by Candida albicans, has highlighted the need of new antifungal denture materials. This study aimed to develop an antifungal heat-curing resin containing quaternary ammonium monomer (dimethylaminododecy...

(This article belongs to the Section Biomaterials)
  • Article
  • Open Access
6 Citations
4,298 Views
13 Pages

The Antibacterial Effects of Quaternary Ammonium Salts in the Simulated Presence of Inhibitors in Root Canals: A Preliminary In-Vitro Study

  • Sanjay Kumar Tiwari,
  • Suping Wang,
  • Yannan Huang,
  • Xuedong Zhou and ,
  • Hockin H. K. Xu,
  • Biao Ren,
  • Xian Peng,
  • Michael D. Weir,
  • Mingyun Li and
  • Lei Cheng
  • + 5 authors+ 0 author

16 February 2020

To investigate the antibacterial effects of two newly developed quaternary ammonium salts (QAMs)-dimethylaminododecyl methacrylate (DMADDM) and dimethylaminohexadecyl methacrylate (DMAHDM), in the presence of various root canal inhibitors. Streptococ...

(This article belongs to the Special Issue Recent Developments in Antibacterial and/or Antifouling Surfaces)
  • Article
  • Open Access
36 Citations
6,647 Views
11 Pages

Novel Dental Adhesive with Biofilm-Regulating and Remineralization Capabilities

  • Yang Ge,
  • Biao Ren,
  • Xuedong Zhou,
  • Hockin H. K. Xu and ,
  • Suping Wang,
  • Mingyun Li,
  • Michael D. Weir,
  • Mingye Feng and
  • Lei Cheng
  • + 4 authors+ 0 author

3 January 2017

The mechanical properties and anti-caries effect of a novel anti-caries adhesive containing poly (amidoamine) dendrimer (PAMAM) and dimethylaminododecyl methacrylate (DMADDM) were investigated for the first time. Microtensile bond strength and surfac...

(This article belongs to the Section Biomaterials)
  • Article
  • Open Access
26 Citations
6,413 Views
11 Pages

Anti-Bacterial and Microecosystem-Regulating Effects of Dental Implant Coated with Dimethylaminododecyl Methacrylate

  • Bolei Li,
  • Yang Ge,
  • Yao Wu,
  • Jing Chen and ,
  • Hockin H. K. Xu,
  • Minggang Yang,
  • Mingyun Li,
  • Biao Ren,
  • Mingye Feng and
  • Xuedong Zhou
  • + 8 authors+ 3 authors

20 November 2017

The effects of dimethylaminododecyl methacrylate (DMADDM) modified titanium implants on bacterial activity and microbial ecosystem of saliva-derived biofilm were investigated for the first time. Titanium discs were coated with DMADDM solutions at mas...

(This article belongs to the Special Issue Antibacterial Materials and Coatings)
  • Article
  • Open Access
49 Citations
8,583 Views
13 Pages

Effect of Antimicrobial Denture Base Resin on Multi-Species Biofilm Formation

  • Keke Zhang,
  • Biao Ren,
  • Xuedong Zhou,
  • Hockin H. K. Xu and ,
  • Yu Chen,
  • Qi Han,
  • Bolei Li,
  • Michael D. Weir,
  • Mingyun Li and
  • Lei Cheng
  • + 6 authors+ 1 author

Our aims of the research were to study the antimicrobial effect of dimethylaminododecyl methacrylate (DMADDM) modified denture base resin on multi-species biofilms and the biocompatibility of this modified dental material. Candida albicans (C. albica...

(This article belongs to the Special Issue Molecular Research on Dental Materials and Biomaterials)
  • Article
  • Open Access
23 Citations
4,474 Views
12 Pages

Effect of Antibacterial Root Canal Sealer on Persistent Apical Periodontitis

  • Zheng Wang,
  • Ge Yang,
  • Biao Ren,
  • Yuan Gao and ,
  • Xian Peng,
  • Mingyun Li,
  • Hockin H.K.Xu,
  • Qi Han,
  • Jiyao Li and
  • Lei Cheng
  • + 6 authors+ 1 author

The infection of Enterococcus faecalis and its interacting microorganisms in the root canal could cause persistent apical periodontitis (AP). Antibacterial root canal sealer has favorable prospects to inhibit biofilms. The purpose of this study was t...

(This article belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
  • Article
  • Open Access
6 Citations
3,269 Views
17 Pages

Novel Antibacterial Resin Coating for Dental Provisional Crowns to Suppress Biofilms and Inhibit Secondary Caries

  • Ibrahim Ba-Armah,
  • Mohammad Alenizy,
  • Nader Almutairi,
  • Heba Alqarni and ,
  • Abdullah Alhussein,
  • Radi Masri,
  • Gary D. Hack,
  • Thomas W. Oates,
  • Jirun Sun and
  • Hockin H. K. Xu
  • + 6 authors+ 1 author

28 October 2024

Provisional crowns are often used in dentistry for prolonged periods, but bacterial attachment and dental plaque often lead to gingival inflammation and secondary caries. The aims of this research were to develop a novel resin-based antibacterial pro...

  • Article
  • Open Access
7 Citations
2,576 Views
15 Pages

Novel Remineralizing and Antibiofilm Low-Shrinkage-Stress Nanocomposites to Inhibit Salivary Biofilms and Protect Tooth Structures

  • Abdullah Alhussein,
  • Rashed Alsahafi,
  • Areej Alfaifi,
  • Mohammad Alenizy and ,
  • Ibrahim Ba-Armah,
  • Abraham Schneider,
  • Mary-Ann Jabra-Rizk,
  • Radi Masri,
  • Guadalupe Garcia Fay and
  • Hockin H. K. Xu
  • + 8 authors+ 3 authors

19 October 2023

Recurrent caries remain a persistent concern, often linked to microleakage and a lack of bioactivity in contemporary dental composites. Our study aims to address this issue by developing a low-shrinkage-stress nanocomposite with antibiofilm and remin...

(This article belongs to the Section Biomaterials)
  • Article
  • Open Access
16 Citations
3,376 Views
17 Pages

Novel Bioactive Nanocomposites Containing Calcium Fluoride and Calcium Phosphate with Antibacterial and Low-Shrinkage-Stress Capabilities to Inhibit Dental Caries

  • Abdullah Alhussein,
  • Rashed Alsahafi,
  • Abdulrahman A. Balhaddad,
  • Lamia Mokeem and ,
  • Abraham Schneider,
  • Mary-Ann Jabra-Rizk,
  • Radi Masri,
  • Gary D. Hack,
  • Thomas W. Oates and
  • Hockin H. K. Xu
  • + 7 authors+ 2 authors

Objectives: Composites are commonly used for tooth restorations, but recurrent caries often lead to restoration failures due to polymerization shrinkage-stress-induced marginal leakage. The aims of this research were to: (1) develop novel low-shrinka...

(This article belongs to the Section Nanobiotechnology and Biofabrication)
  • Article
  • Open Access
11 Citations
4,374 Views
12 Pages

Effect of the Modified Methacrylate-Based Root Canal Sealer in Single-Cone Technique

  • Yu Fan,
  • Zheng Wang,
  • Yan Sun,
  • Xiao Guo and ,
  • Haohao Wang,
  • Hockin H. K. Xu,
  • Suping Wang,
  • Xuedong Zhou,
  • Bolei Li and
  • Lei Cheng
  • + 5 authors+ 0 author

23 October 2022

This study aimed to modify EndoREZ with 2.5% dimethylaminododecyl methacrylate (DMADDM) and 1% magnetic nanoparticles (MNP) to study its sealing property, penetration and long-term antibacterial and therapeutic effect in the single-cone technique (SC...

(This article belongs to the Special Issue New Insights in Nanomaterials for Dental Diseases Management)
  • Article
  • Open Access
13 Citations
3,985 Views
18 Pages

Novel Giomers Incorporated with Antibacterial Quaternary Ammonium Monomers to Inhibit Secondary Caries

  • Yandi Chen,
  • Bina Yang,
  • Lei Cheng,
  • Hockin H. K. Xu and ,
  • Hao Li,
  • Yuyao Huang,
  • Qiong Zhang,
  • Xuedong Zhou,
  • Jingou Liang and
  • Jing Zou
  • + 5 authors+ 0 author

The objective of this study was to develop novel modified giomers by incorporating the antibacterial quaternary ammonium monomers (QAMs), dimethylaminododecyl methacrylate (DMADDM) or dimethylaminohexadecyl methacrylate (DMAHDM) into a commercial gio...

(This article belongs to the Special Issue Insights in Oral Microbiota)
  • Article
  • Open Access
1,410 Views
22 Pages

Development of Remineralizing and Antibacterial Resin Coating for Provisional Crowns with Improved Bond Strength and Wear Resistance

  • Ibrahim Ba-Armah,
  • Abdullah Alhussein,
  • Nader Almutairi,
  • Mohammad Alenizy and ,
  • Heba Alqarni,
  • Yazeed Altamimi,
  • Ayman Altamimi,
  • Radi Masri,
  • Jirun Sun and
  • Hockin H. K. Xu
  • + 6 authors+ 1 author

12 April 2026

Secondary caries and biofilm accumulation remain major causes of failure in provisional crowns and restorations, highlighting the need for multifunctional resin coatings with antibacterial and remineralizing capabilities. This study aimed to develop...

(This article belongs to the Special Issue Functional Polymeric Materials for Dental and Oral and Maxillofacial Surgery Applications)