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21 Results Found

  • Article
  • Open Access
2,591 Views
14 Pages

The Image Clarity Paradox: Higher CZT SPECT Contrast Does Not Always Translate to Diagnostic Accuracy for Alzheimer’s Disease

  • Kiyotaka Nemoto,
  • Bryan J. Mathis,
  • Akemi Iwasaka,
  • Kenjiro Nakayama and ,
  • Tomohiro Kaneta and
  • Tetsuaki Arai
  • + 1 author+ 0 author

Background: Recent advances in single-photon emission computed tomography (SPECT) technology, particularly cadmium–zinc–telluride (CZT) detectors, have improved spatial resolution and contrast in cerebral blood flow imaging. This study ai...

  • Article
  • Open Access
351 Views
16 Pages

Value of Multi-Parameter Combined Application of CZT-SPECT and CCTA in Risk Stratification of Short-Term Myocardial Ischemic Events in Patients with Chronic Coronary Syndromes

  • Jing Ni,
  • Zekun Pang,
  • Haoran Guo,
  • Ajay Kumar Chaudhary and ,
  • Fukai Zhao,
  • Yue Chen,
  • Jiao Wang and
  • Jianming Li
  • + 3 authors+ 0 author

Background: This study aimed to investigate the predictive value of the multi-parameter combined application of cadmium–zinc–telluride single-photon emission computed tomography (CZT-SPECT) and coronary computed tomography angiography (CC...

(This article belongs to the Section Imaging)
  • Article
  • Open Access
6 Citations
5,234 Views
12 Pages

Head-to-Head Comparison of CZT-SPECT and SPECT/CT Myocardial Perfusion Imaging: Interobserver and Intraobserver Agreement and Diagnostic Performance

  • Forough Kalantari,
  • Nasibeh Mohseninia,
  • Andreas Wetsch,
  • Sara Harsini and ,
  • Lukas Hehenwarter,
  • Gregor Schweighofer-Zwink,
  • Nazanin Zamani-Siahkali,
  • Gundula Rendl,
  • Mohsen Beheshti and
  • Christian Pirich
  • + 5 authors+ 0 author

7 September 2023

Background: Myocardial perfusion imaging (MPI) plays a crucial role in diagnosing coronary artery disease (CAD), with single-photon emission computed tomography (SPECT) being a widely accepted method. The accuracy of MPI relies on image quality and t...

(This article belongs to the Special Issue New Advances in Cardiac Imaging)
  • Article
  • Open Access
14 Citations
11,363 Views
17 Pages

CZT Detectors-Based SPECT Imaging: How Detector and Collimator Arrangement Can Determine the Overall Performance of the Tomograph

  • Maria Filomena Santarelli,
  • Anna Mori,
  • Michelangelo Bertasi,
  • Vincenzo Positano and ,
  • Alessia Gimelli,
  • Michele Scipioni,
  • Paolo Marzullo and
  • Luigi Landini
  • + 3 authors+ 0 author

11 September 2021

A technical comparison is described between two SPECT systems, one dedicated to cardiovascular studies and one general-purpose, to evaluate the advantages and disadvantages of their use in an organ-specific clinical setting. The comparison was made b...

(This article belongs to the Special Issue Digital Twin Technology: New Frontiers for Personalized Healthcare)
  • Article
  • Open Access
4 Citations
6,539 Views
12 Pages

27 May 2016

In this paper, we propose a wobbling method to correct bad pixels in cadmium zinc telluride (CZT) detectors, using information of related images. We build up an automated device that realizes the wobbling correction for small animal Single Photon Emi...

(This article belongs to the Special Issue Imaging: Sensors and Technologies)
  • Article
  • Open Access
22 Citations
4,007 Views
11 Pages

7 January 2021

This study analyzes CZT SPECT myocardial perfusion images that are collected at Chang Gung Memorial Hospital, Kaohsiung Medical Center in Kaohsiung. This study focuses on the classification of myocardial perfusion images for coronary heart diseases b...

(This article belongs to the Special Issue Advanced Image Analysis and Processing for Biomedical Applications)
  • Article
  • Open Access
401 Views
18 Pages

3 September 2026

Background/Objectives: We aimed to compare the diagnostic performances of planar bone scintigraphy and whole-body 360° cadmium–zinc–telluride (CZT) bone single-photon emission computed tomography/computed tomography (SPECT/CT) in dete...

(This article belongs to the Special Issue Recent Advances in the Diagnosis and Prognosis of Lung Cancer)
  • Study Protocol
  • Open Access
1 Citations
2,548 Views
9 Pages

The prevalence of coronary artery disease (CAD) in patients with severe aortic stenosis (AS) is 30–68%. Nevertheless, there is still not enough evidence to use invasive assessment of lesion severity, because the hemodynamic milieu of AS may imp...

(This article belongs to the Special Issue Biomaterials for Cardiovascular Repairs and Cardiovascular Biomechanics)
  • Article
  • Open Access
4 Citations
2,278 Views
11 Pages

An Algorithm for Individual Dosage in Cadmium–Zinc–Telluride SPECT-Gated Radionuclide Angiography

  • Maria Normand Hansen,
  • Christian Haarmark,
  • Bent Kristensen and
  • Bo Zerahn

4 December 2021

The aim of the present study was to test an individualised dose without compromising the ease of analysing data when performing equilibrium radionuclide angiography (ERNA) using cadmium–zinc–telluride (CZT) SPECT. From March 2018 to Janua...

(This article belongs to the Topic Medical Image Analysis)
  • Review
  • Open Access
5 Citations
4,333 Views
11 Pages

17 November 2021

This paper presents a review of the literature concerning the clinical application of modern semiconductor (CZT) gamma cameras in the radioinuclide diagnosis of coronary artery disease. It contains information on the diagnostic efficacy of myocardial...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
10 Citations
1,885 Views
17 Pages

23 February 2024

(1) Background: The objective of this study was to determine the optimal post-processing model for dynamic cadmium–zinc–telluride single-photon emission computed tomography (CZT-SPECT). (2) Methods: A total of 235 patients who underwent d...

(This article belongs to the Section Cardiovascular Medicine)
  • Article
  • Open Access
1,072 Views
13 Pages

Background: Left ventricular ejection fraction remains the primary focus in cardiac monitoring for oncology patients undergoing potentially cardiotoxic chemotherapy, while right ventricular function is seldom examined. This study evaluates how establ...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Case Report
  • Open Access
1 Citations
2,690 Views
7 Pages

17 August 2022

Perfusion scintigraphy with the acquisition of planar blood flow and pool images of bilateral hands has been used to aid diagnosis and to evaluate treatment response to Raynaud’s phenomenon (decreased blood flow to hand or foot). However, becau...

  • Article
  • Open Access
1 Citations
836 Views
13 Pages

Background: The prevalence of chronic total occlusion (CTO) lesions is as high as 30% in patients undergoing coronary angiography (CAG). Some CTO patients do not undergo revascularization due to procedural complexity and high risks. This study aimed...

(This article belongs to the Special Issue Noninvasive Imaging in Cardiology: From Diagnosis to Treatment)
  • Article
  • Open Access
1 Citations
4,496 Views
11 Pages

4 April 2025

Background and Objectives: Single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is a well-established technique for evaluating myocardial perfusion and function in patients with suspected or known coronary artery dise...

(This article belongs to the Section Cardiology)
  • Review
  • Open Access
59 Citations
22,482 Views
20 Pages

Technological Advances in SPECT and SPECT/CT Imaging

  • Yassine Bouchareb,
  • Afrah AlSaadi,
  • Jawa Zabah,
  • Anjali Jain and ,
  • Aziza Al-Jabri,
  • Peter Phiri,
  • Jian Qing Shi,
  • Gayathri Delanerolle and
  • Srinivasa Rao Sirasanagandla
  • + 4 authors+ 0 author

Single photon emission tomography/computed tomography (SPECT/CT) is a mature imaging technology with a dynamic role in the diagnosis and monitoring of a wide array of diseases. This paper reviews the technological advances, clinical impact, and futur...

(This article belongs to the Special Issue Research Update on Nuclear Medicine)
  • Article
  • Open Access
26 Citations
5,607 Views
11 Pages

Potentialities of High-Resolution 3-D CZT Drift Strip Detectors for Prompt Gamma-Ray Measurements in BNCT

  • Leonardo Abbene,
  • Fabio Principato,
  • Antonino Buttacavoli,
  • Gaetano Gerardi and ,
  • Manuele Bettelli,
  • Andrea Zappettini,
  • Saverio Altieri,
  • Natalia Auricchio,
  • Ezio Caroli and
  • Nicoletta Protti
  • + 6 authors+ 1 author

15 February 2022

Recently, new high-resolution cadmium–zinc–telluride (CZT) drift strip detectors for room temperature gamma-ray spectroscopic imaging were developed by our group. The CZT detectors equipped with orthogonal anode/cathode collecting strips,...

(This article belongs to the Special Issue CdZnTe Radiation Detectors and Applications)
  • Article
  • Open Access
6 Citations
2,568 Views
13 Pages

2 December 2024

Background/Objectives: This study aimed to assess the diagnostic capability of quantitative parameters from whole-body bone single-photon emission computed tomography/computed tomography (SPECT/CT) in detecting bone metastases in prostate cancer pati...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
530 Views
19 Pages

Accurate quantitative SPECT depends strongly on the reconstruction protocol, particularly for penalised-likelihood reconstruction algorithms, such as Q.Clear (BSREM). This study aimed to optimise Q.Clear reconstruction parameters for 123I and 177Lu i...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
9 Citations
2,598 Views
12 Pages

Inter- and Intraobserver Repeatability of Myocardial Flow Reserve Values Determined with SPECT Study Using a Discovery NM530c Camera and Corridor 4DM Software

  • Paweł Cichocki,
  • Michał Błaszczyk,
  • Kamila Cygulska,
  • Krzysztof Filipczak and ,
  • Zbigniew Adamczewski,
  • Jacek Kuśmierek,
  • Piotr Lipiec,
  • Jarosław Damian Kasprzak and
  • Anna Płachcińska
  • + 4 authors+ 0 author

9 November 2021

Background: Myocardial blood flow (MBF) and flow reserve (MFR) examination, especially useful in the diagnosis of multivessel coronary artery disease (CAD), can be assessed with a cadmium-zinc-telluride (CZT) SPECT gamma camera, as an alternative to...

(This article belongs to the Special Issue Cardiac Disease: Diagnosis, Treatment, and Outcomes)
  • Article
  • Open Access
15 Citations
3,153 Views
14 Pages

Coronary Microvascular Dysfunction: Features and Prognostic Value

  • Kristina Kopeva,
  • Elena Grakova,
  • Alina Maltseva,
  • Andrew Mochula and ,
  • Anna Gusakova,
  • Andrew Smorgon and
  • Konstantin Zavadovsky
  • + 2 authors+ 0 author

19 April 2023

(1) Background: The results of the international studies support the assumption that coronary microvascular dysfunction (CMD) occurs significantly more often than previously identified and is associated with adverse outcomes. However, there is a lack...

(This article belongs to the Section Cardiovascular Medicine)