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25 Results Found

  • Article
  • Open Access
2 Citations
6,856 Views
11 Pages

Cutaneous Canine Mast Cell Tumor: The Use of Proliferative Markers (Ki-67 and Ki-67 × AgNOR) in Cytological Samples for Diagnosis and Prognosis

  • Christina Marouda,
  • Tilemahos Anagnostou,
  • Barbara Brunetti,
  • Ioannis Savvas,
  • Lysimachos G. Papazoglou and
  • Dimitra Psalla

7 January 2024

A cytological grading system for canine mast cell tumors (MCTs) has been developed, but its integration into clinical routine has been hindered due to its diagnostic limitations. The aim of this study was to assess the prognostic value of Ki-67 and a...

  • Abstract
  • Open Access
1 Citations
2,428 Views
1 Page

Determination of Silymarin Molecule Activity in Colon Cancer by AgNOR Technique

  • Merve Alpay,
  • Recep Eröz,
  • Gorkem Kısmalı and
  • Efe Kurtdede

16 November 2017

Silymarin is from the seeds of S.marinaceous plant which is liver protective agent used in various diseases like cirrhosis, toxic chemicals, hepatitis. Previous researches have reported effects anti-inflammatory, antiapoptotic, anti-carcinogenic, ant...

  • Article
  • Open Access
9 Citations
2,782 Views
11 Pages

(1) Background: ST-elevation myocardial infarction (STEMI) is an inflammatory disease in which neutrophils, macrophages, and lymphocytes accumulate in the ischemic myocardium and have important functions. Nucleolar-organizing regions (NORs) are the s...

  • Article
  • Open Access
7 Citations
2,440 Views
13 Pages

29 October 2021

Background and Objectives: It is of great importance to obtain information about the severity of ischemic damage and duration of testicular torsion for an effective treatment strategy. Nucleolar-organizing regions (NORs) are sites of the ribosomal ge...

  • Article
  • Open Access
4 Citations
6,130 Views
16 Pages

Glucocorticoid administration is a common clinical practice that attempts to decrease the inflammation associated with and improve the resectability of canine mast cell tumors (MCTs). However, the impact of neoadjuvant glucocorticoids on the histolog...

  • Article
  • Open Access
3 Citations
3,908 Views
11 Pages

Analysis of Argyrophilic Nucleolar Organizer Regions (AgNORs) in Acute Leukemia in Adults

  • Małgorzata Gajewska,
  • Elżbieta Rutkowska,
  • Iwona Kwiecień,
  • Piotr Rzepecki and
  • Kazimierz Sułek

The evaluation of argyrophilic nucleolar organizer regions (AgNORs) uses a simple method used in research into neoplasm. Bone marrow aspirates from 70 patients with acute leukemia underwent morphological, immunophenotypic, and genetic assessment and...

  • Article
  • Open Access
12 Citations
3,983 Views
9 Pages

10 September 2022

The prognostic significance of internal tandem duplication (ITD) mutations in exons 8 and 11 of c-kit has been well-described for canine cutaneous mast cell tumors (MCTs), but c-kit mutations have rarely been reported in subcutaneous MCTs. The object...

  • Article
  • Open Access
3 Citations
2,813 Views
7 Pages

Roles of Proliferation and Angiogenesis in Locally Aggressive Biologic Behavior of Ameloblastoma versus Ameloblastic Fibroma

  • Amr Ibrahim,
  • Emad Alqalshy,
  • Ahmed Abdel-Shakour Abdel-Hafiz,
  • Kamal Abd El-Rahman and
  • Magdy Alazzazi

(1) Background: The present study was carried out to evaluate the roles of proliferation and angiogenesis in locally aggressive biologic behavior of ameloblastoma versus ameloblastic fibroma; (2) Methods: 30 formalin-fixed paraffin embedded blocks (1...

  • Article
  • Open Access
8 Citations
4,553 Views
16 Pages

Chromosomes of Asian Cyprinid Fishes: Genomic Differences in Conserved Karyotypes of ‘Poropuntiinae’ (Teleostei, Cyprinidae)

  • Sudarat Khensuwan,
  • Francisco de M. C. Sassi,
  • Renata L. R. Moraes,
  • Sitthisak Jantarat,
  • Kriengkrai Seetapan,
  • Krit Phintong,
  • Weera Thongnetr,
  • Sarawut Kaewsri,
  • Sarun Jumrusthanasan and
  • Marcelo B. Cioffi
  • + 4 authors

20 April 2023

The representatives of cyprinid lineage ‘Poropuntiinae’ with 16 recognized genera and around 100 species form a significant part of Southeast Asian ichthyofauna. Cytogenetics are valuable when studying fish evolution, especially the dynam...

  • Review
  • Open Access
7 Citations
3,796 Views
26 Pages

Structure and Evolution of Ribosomal Genes of Insect Chromosomes

  • Vladimir E. Gokhman and
  • Valentina G. Kuznetsova

4 August 2024

Currently, clusters of 45S and 5S ribosomal DNA (rDNA) have been studied in about 1000 and 100 species of the class Insecta, respectively. Although the number of insect species with known 45S rDNA clusters (also referred to as nucleolus-organizing re...

  • Review
  • Open Access
198 Citations
13,966 Views
15 Pages

The Ribosome Biogenesis—Cancer Connection

  • Marianna Penzo,
  • Lorenzo Montanaro,
  • Davide Treré and
  • Massimo Derenzini

15 January 2019

Multifaceted relations link ribosome biogenesis to cancer. Ribosome biogenesis takes place in the nucleolus. Clarifying the mechanisms involved in this nucleolar function and its relationship with cell proliferation: (1) allowed the understanding of...

  • Article
  • Open Access
16 Citations
3,399 Views
13 Pages

Analyses of the Updated “Animal rDNA Loci Database” with an Emphasis on Its New Features

  • Jana Sochorová,
  • Francisco Gálvez,
  • Roman Matyášek,
  • Sònia Garcia and
  • Aleš Kovařík

22 October 2021

We report on a major update to the animal rDNA loci database, which now contains cytogenetic information for 45S and 5S rDNA loci in more than 2600 and 1000 species, respectively. The data analyses show the following: (i) A high variability in 5S and...

  • Article
  • Open Access
5 Citations
3,515 Views
13 Pages

6 November 2020

Supernumerary B chromosomes (Bs) are very promising structures, among others, in that they are an additional genomic compartment for evolution. In this study, we tested the presence and frequency of B chromosomes and performed the first cytogenetic e...

  • Article
  • Open Access
1,046 Views
12 Pages

The Curious Case of Woodcreepers: Cytogenomic Evidence Based on the Position of NORs

  • Analía del Valle Garnero,
  • Vitor Oliveira de Rosso,
  • Hybraim Severo Salau,
  • Paulo Afonso Rosa de Lara,
  • Victoria Tura,
  • Fabiano Pimentel Torres and
  • Ricardo José Gunski

14 August 2025

Woodcreepers (Dendrocolaptinae) constitute a subfamily of Neotropical passerines currently recognized as a monophyletic group within Furnariidae. Although Furnariidae is one of the most diverse avian families in the Neotropics, cytogenetic data remai...

  • Article
  • Open Access
4 Citations
2,487 Views
17 Pages

Chemopreventive Effect of Cooked Chickpea on Colon Carcinogenesis Evolution in AOM/DSS-Induced Balb/c Mice

  • María Stephanie Cid-Gallegos,
  • Cristian Jiménez-Martínez,
  • Xariss M. Sánchez-Chino,
  • Eduardo Madrigal-Bujaidar,
  • Verónica R. Vásquez-Garzón,
  • Rafael Baltiérrez-Hoyos and
  • Isela Álvarez-González

14 June 2023

Chickpeas are one of the most widely consumed legumes worldwide and they might prevent diseases such as cancer. Therefore, this study evaluates the chemopreventive effect of chickpea (Cicer arietinum L.) on the evolution of colon carcinogenesis induc...

  • Article
  • Open Access
5 Citations
3,584 Views
13 Pages

Karyotypic and Molecular Analysis of Pterygoplichthys pardalis (Castelnau 1855) from the Lower Amazon River

  • Alcimara dos Santos Guimarães,
  • Luan Aércio Melo Maciel,
  • Mendelshon Fujiie Belém de Souza and
  • Luís Reginaldo Ribeiro Rodrigues

3 May 2023

Pterygoplichthys pardalis is an armored catfish native to South America and an important resource for the ornamental fish industry. Recently, several exotic populations have been introduced into rivers on five continents. Despite its commercial and e...

  • Article
  • Open Access
3 Citations
1,850 Views
12 Pages

22 June 2023

We performed a molecular and phylogenetic analysis and a comparative cytogenetic study with standard karyotyping, silver staining (Ag-NOR) and sequential C-banding + Giemsa, + fluorochromes on several Blaesodactylus samples. The phylogenetic inferenc...

  • Systematic Review
  • Open Access
2 Citations
2,313 Views
10 Pages

Are Cytomorphogenetic Events Correlated with Oral Mucosal Lesions Induced by Crack Cocaine Use? A Systematic Review

  • Thiago Guedes Pinto,
  • Milena de Barros Viana,
  • Patricia Ramos Cury,
  • Manoela Domingues Martins,
  • Jean Nunes dos Santos and
  • Daniel Araki Ribeiro

The aim of this systematic review was to answer the question of whether crack cocaine can induce cellular and molecular alterations and whether such alterations are somehow related to clinical lesions in the oral mucosa. The searches were undertaken...

  • Article
  • Open Access
1 Citations
3,932 Views
11 Pages

Supernumerary Marker Chromosome Identified in Asian Elephant (Elephas maximus)

  • Halina Cernohorska,
  • Svatava Kubickova,
  • Petra Musilova,
  • Miluse Vozdova,
  • Roman Vodicka and
  • Jiri Rubes

17 February 2023

We identified a small, supernumerary marker chromosome (sSMC) in two phenotypically normal Asian elephants (Elephas maximus): a female (2n = 57,XX,+mar) and her male offspring (2n = 57,XY,+mar). sSMCs are defined as structurally abnormal chromosomes...

  • Feature Paper
  • Article
  • Open Access
1,665 Views
11 Pages

6 June 2024

We present a comparative chromosome study of several taxa of the Malagasy ground geckos of the Paroedura bastardi and P. picta species groups. We employed a preliminary molecular analysis using a trait of the mitochondrial 16S rRNA gene (of about 570...

  • Article
  • Open Access
1 Citations
2,089 Views
11 Pages

25 January 2024

This contribution provides the first karyotype description of Hemidactylus mercatorius and discusses the interspecific chromosome diversification in the genus. Chromosomal analysis was performed on samples from different Malagasy populations using st...

  • Article
  • Open Access
11 Citations
2,860 Views
12 Pages

12 August 2022

We provide here the first karyotype description of eight Uroplatus species and a characterization of their chromosomal diversity. We performed a molecular taxonomic assessment of several Uroplatus samples using the mitochondrial 12S marker and a comp...

  • Article
  • Open Access
4 Citations
7,489 Views
13 Pages

Τhe Effect of Opioid Administration on Cytologic and Histopathologic Diagnosis of Canine Cutaneous Mast Cell Tumors Treated by Surgical Excision

  • Christina Marouda,
  • Tilemahos Anagnostou,
  • Ioannis Savvas,
  • Lysimachos G. Papazoglou and
  • Dimitra Psalla

22 April 2022

Mast cell tumor (MCT) is a frequent cutaneous tumor in dogs, with a variable biological behavior. Studies correlate cytologic and histopathologic features of MCTs with their biological behavior, prognosis, and response to treatment. The use of preope...

  • Article
  • Open Access
2 Citations
2,127 Views
13 Pages

Oxidative Status and Lipid Metabolism Analytes in Dogs with Mast Cell Tumors: A Preliminary Study

  • Argyrios Ginoudis,
  • Dimitra Pardali,
  • Mathios E. Mylonakis,
  • Androniki Tamvakis,
  • Asta Tvarijonaviciute,
  • Evgenia Lymperaki,
  • Jose Joaquin Ceron and
  • Zoe Polizopoulou

29 November 2024

Mast cell tumors (MCTs) are common skin neoplasms in dogs. Prognostic indicators include histologic grade, clinical stage, high Ki-67 index, elevated argyrophilic nucleolus organizer regions (AgNOR) index, c-kit mutations, and recurrence after surger...

  • Article
  • Open Access
9 Citations
3,131 Views
15 Pages

18 August 2022

Taxonomy in Bufonidae witnessed notable transformations. Bufotes viridis and Epidalea calamita, previously included in genus Bufo, were relocated in other genera, while the genus Bufo was restricted to members of the earlier Bufo bufo group. On the o...