Special Issues

Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Factors Influencing Vaccine Uptake and Immunization Outcomes
edited by Sitong Luo, Meiqi Xin and
submission deadline 30 Apr 2026 | 1 articles | Viewed by 728 | Submission Open
Keywords: vaccination; vaccine uptake; immunization
(This special issue belongs to the Section Vaccines and Public Health)
Immunological Responses to mRNA Vaccines
edited by Hyeri Seok
submission deadline 30 Apr 2026 | Viewed by 393 | Submission Open
Keywords: infectious; vaccine; immune response; immunogenicity; vaccine-induced immunity
The Need for an HIV Vaccine in the Era of Highly Effective PrEP
edited by Michele Peake Andrasik, William O. Hahn and Susan P. Buchbinder
submission deadline 30 Apr 2026 | Viewed by 347 | Submission Open
Keywords: HIV; vaccines; HIV prevention; bnAbs; clinical trials
(This special issue belongs to the Section HIV Vaccines)
Oral Vaccines: Challenges, Immunity and Therapeutic Advances
edited by Amin Safa
submission deadline 30 Apr 2026 | Viewed by 306 | Submission Open
Keywords: oral vaccines; mucosal immunity; Peyer’ s patches; nanoparticles; probiotic delivery; cancer immunotherapy; gastrointestinal barriers; antigen presentation
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
State of the Art of Flavivirus Virus Research
edited by
submission deadline 30 Apr 2026 | Viewed by 273 | Submission Open
Keywords: flavivirus; vaccine; infection control; diagnosis; epidemiology
(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
Genetically Engineered Mouse Models in Vaccine Development
edited by Deshan Ren and
submission deadline 30 Apr 2026 | Viewed by 203 | Submission Open
Keywords: vaccine; immunogenicity; knockout; knockin; transgenic mice; humanized mice; xenografts; NCG/NKG/NRG/NSG; viruses
(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)
New Challenges in Vaccines and Vaccination: A Public Health Perspective submission deadline 30 Apr 2026 | 2 articles | Viewed by 143 | Submission Open
Keywords: vaccine effectiveness/efficacy; vaccination strategies; tailored approaches for different populations; public health
(This special issue belongs to the Section Vaccines and Public Health)
Tumor Vaccines: Current Processes, Prevailing Challenges and Future Perspectives
edited by Xingxing He and Honglin Jin
submission deadline 1 May 2026 | 8 articles | Viewed by 34611 | Submission Open
Keywords: tumor vaccine; mRNA vaccine; personalized medicine; adjuvant; delivery strategies; cancer immunotherapy; personalized vaccines
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
Exploring Cutaneous Autoimmune Disease Flares in the Wake of COVID-19 Infection and Vaccination
edited by Angeliki-Victoria Roussaki-Schulze, Efterpi Zafiriou and
submission deadline 10 May 2026 | Viewed by 472 | Submission Open
Keywords: COVID-19 infection; COVID-19 vaccination; psoriasis; inflammatory dermatoses; alopecia; bullous dermatoses; adverse reactions; exanthem
(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)
Swine Vaccines and Vaccination
edited by
submission deadline 15 May 2026 | 4 articles | Viewed by 5021 | Submission Open
Keywords: swine fever; classical swine fever virus; african swine fever virus; live attenuated vaccines; subunit vaccines; nanopartical vaccines
(This special issue belongs to the Section Veterinary Vaccines)
Vaccination and Treatments Against Viral Hepatitis: Achievements, Challenges and Perspectives, 2nd Edition submission deadline 20 May 2026 | Viewed by 271 | Submission Open
Keywords: vaccination; treatments; viral hepatitis; hepatitis A– E
(This special issue belongs to the Section Hepatitis Virus Vaccines)
Innovative Vaccines and Technologies to Address Tropical Parasitic Diseases
edited by , and Fernando Sanchez-Valdez
submission deadline 30 May 2026 | Viewed by 217 | Submission Open
Keywords: tropical parasitic diseases; vaccine development; chimeric and multiepitope vaccines; immunomodulation and adjuvants; host– parasite interaction; biotechnology-based vaccine platforms
(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
Vaccination, Public Health and Epidemiology
edited by
submission deadline 31 May 2026 | 9 articles | Viewed by 21176 | Submission Open
Keywords: vaccine; vaccinology; epidemiology; infectious diseases; public health; emerging infectious diseases; tropical neglected diseases
(This special issue belongs to the Section Vaccines and Public Health)
Clinical Strategies to Improve Efficacy, Effectiveness, and Safety of Vaccination in Humans
edited by
submission deadline 31 May 2026 | 10 articles | Viewed by 17948 | Submission Open
Keywords: adenovirus vaccines; immunologic adjuvants; adult; communicable diseases; geriatrics; immunocompromised Host; mRNA vaccines; pediatrics; public health; attenuated vaccines; inactivated vaccines
(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)
Population Immunity and Persistence to SARS-CoV-2 Induced by Infection and Vaccination, Protection Against New Infections and Implication for Further Vaccination: 2nd Edition
edited by Juan Yang and Wei Wang
submission deadline 31 May 2026 | 4 articles | Viewed by 9411 | Submission Open
Keywords: SARS-CoV-2; COVID-19; serology; population immunity; hybrid immunity; vaccination; antibody kinetics; cross-protection
(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)
A One-Health Perspective on Immunization Against Infectious Diseases
edited by Jose Camilla Sammartino
submission deadline 31 May 2026 | 4 articles | Viewed by 8752 | Submission Open
Keywords: One-Health vaccinology; immunization; vaccine; antibody; infectious disease; emerging pathogens; climate change; sustainability
(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
Research on HIV/AIDS Vaccine
edited by Portia Chipo Mutevedzi and
submission deadline 31 May 2026 | 3 articles | Viewed by 7564 | Submission Open
Keywords: HIV; antiretroviral treatment (ART); vaccines; drug resistance; vaccine efficacy
(This special issue belongs to the Section HIV Vaccines)
Safety and Immunogenicity of Vaccination
edited by Jennifer Serwanga
submission deadline 31 May 2026 | 5 articles | Viewed by 7442 | Submission Open
Keywords: vaccine safety; immunogenicity profiling; correlates of protection; vaccine-induced immunity; dose optimization and adjuvants; breakthrough infections; long-term immune memory; vaccines in special populations
(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)
Vaccines to Achieve Affordable Universal Coverage
edited by Pui Hong Chung
submission deadline 31 May 2026 | 2 articles | Viewed by 7366 | Submission Open
Keywords: Sustainable Development Goals (SDGs); global health; vaccines; vaccine equity; vaccine disparities; vaccine accessibility; vaccination literacy; vaccine innovation; disease prevention; vaccine policy and implementation; public health policy; health economics; healthcare disparities; universal health coverage; international health partnerships
(This special issue belongs to the Section Vaccines and Public Health)
Animal Infectious Diseases and Vaccinology in One Health
edited by and Elizabeth Loza-Rubio
submission deadline 31 May 2026 | 2 articles | Viewed by 2913 | Submission Open
Keywords: vaccinology; productive animals; one health; infectious diseases; zoonoses
(This special issue belongs to the Section Veterinary Vaccines)
Vaccine, Preventive Strategies and Antiviral Responses to Zoonotic Viruses
edited by , Shu Shen, Chen Peng and Ben Hu
submission deadline 31 May 2026 | 1 articles | Viewed by 2493 | Submission Open
Keywords: alphavirus; arenavirus; bunyavirus; coronavirus; flavivirus; filovirus; orthomyxovirus (e.g.; avian influenza virus); orthopoxvirus; paramyxovirus; rhabdovirus
(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
Innovative Vaccines That Modulate the Immune System to Enhance Cancer Therapy
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 1867 | Submission Open
Keywords: cancer vaccines; CAR T cell therapy; checkpoint-inhibitors; combination therapy; tumor microenvironment; tumor-infiltrating lymphocytes
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
Advances in the Use of Nanoparticles for Vaccine Platform Development: 2nd Edition
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 1497 | Submission Open
Keywords: nanoparticles; vaccine; immunotherapy; subunit vaccine; RNA vaccine; adjuvant; nanotechnology
(This special issue belongs to the Section Vaccine Design, Development, and Delivery)
Advances in ImmunoTherapy of Cancer
edited by Li Ye and Jiajun Fan
submission deadline 31 May 2026 | 1 articles | Viewed by 1380 | Submission Open
Keywords: cancer vaccines; neoantigen; immunotherapy; cancer microenviroment
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
Factors Affecting and Strategies Enhancing the Willingness to Receive and Uptake of Seasonal Influenza Vaccination submission deadline 31 May 2026 | 1 articles | Viewed by 874 | Submission Open
Keywords: factors; strategies; willingness; uptake; seasonal influenza vaccination
(This special issue belongs to the Section Vaccines and Public Health)
SARS-CoV-2 Pathogenesis, Vaccines and Therapeutics submission deadline 31 May 2026 | 1 articles | Viewed by 849 | Submission Open
Keywords: vaccine; SARS-CoV-2; COVID-19; antibodies; antivirals
(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)
Therapeutic Cancer Vaccines: Advances, Challenges, and Future Directions
edited by Erminia Massarelli and Victoria M. Villaflor
submission deadline 31 May 2026 | Viewed by 453 | Submission Open
Keywords: therapeutic cancer vaccines; clinical trials; solid tumors; malignant hematology; peptide vaccines; DNA vaccines; vector vaccines; dendritic cell vaccines; allogenic vaccines; mRNA vaccines
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
Vaccines Based on Dendritic Cells: Breaking Barriers to New Immune Response Approach submission deadline 31 May 2026 | Viewed by 443 | Submission Open
Keywords: plasmacytoid dendritic cells; myeloid dendritic cells; immunotolerance; regulatory T cells; cytotoxic T cells; NK cells; immunotherapies; nanovaccines; immunometabolism; delivery systems
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
Recent Research on Adenovirus-Vectored Vaccines submission deadline 31 May 2026 | 1 articles | Viewed by 331 | Submission Open
Keywords: adenovirus; replication competent; single cycle; replication defective; serotypes; targeting; structure; cryo-EM; vaccines
(This special issue belongs to the Section Vaccine Design, Development, and Delivery)
Avian Viruses and the Host Immune System
edited by , Junfeng Lv and
submission deadline 31 May 2026 | Viewed by 291 | Submission Open
Keywords: avian; waterfowl; viral diseases; vaccination strategies; viral vector development; host immune response
(This special issue belongs to the Section Veterinary Vaccines)
NK Cell-Mediated Immune Responses and Tumor Defense
edited by and Luc Van Kaer
submission deadline 31 May 2026 | Viewed by 278 | Submission Open
Keywords: innate immunity; metastasis; MHC class I; immunotherapy; cytokines; STING; IFNγ ; NK cell engager; CD8 T cell; chimeric antigen receptors (CARs)
(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)
Virus-Like Particle (VLP) Vaccines Against Emerging Infectious Diseases—2nd Edition
edited by
submission deadline 31 May 2026 | Viewed by 275 | Submission Open
Keywords: emerging infectious diseases (EIDs); virus-like particle (VLP); vaccines
(This special issue belongs to the Section Vaccine Design, Development, and Delivery)
Advances in Serologic Assays for Vaccination Monitoring and Assessment of Immune Protection
edited by Paul D. Olivo and Randolph F.R. Rasch
submission deadline 31 May 2026 | Viewed by 265 | Submission Open
Keywords: vaccines; vaccine-preventable diseases; antibodies; serology; correlates of protection; biomarkers of immunity; immunosurveillance
(This special issue belongs to the Section Epidemiology and Vaccination)
Vaccines and Immune-Modulators for Mammalian Livestock Species
edited by , Eliane Isabelle Marti, and Rupam Dutta
submission deadline 31 May 2026 | Viewed by 197 | Submission Open
Keywords: vaccines; mammalian species; adjuvants; immune-modulators
(This special issue belongs to the Section Veterinary Vaccines)
Vaccines Against Swine Respiratory Diseases
edited by Jairo Jaime
submission deadline 31 May 2026 | Viewed by 177 | Submission Open
Keywords: porcine respiratory disease complex (PRDC); vaccines; innate and adaptive immunity; viruses; bacteria; adjuvants; new vaccination strategies
(This special issue belongs to the Section Veterinary Vaccines)
Evaluating Immunisation Programmes to Optimise Vaccination Strategies and Strengthen Vaccines Impact
edited by Irina Kislaya and Ausenda Machado
submission deadline 31 May 2026 | Viewed by 166 | Submission Open
Keywords: immunisation programme; impact; evaluation; implementation
(This special issue belongs to the Section Epidemiology and Vaccination)
Novel Adjuvants and Delivery Technologies for Vaccine Development submission deadline 31 May 2026 | Viewed by 150 | Submission Open
Keywords: adjuvants; vaccine delivery systems; immunogenicity; nanotechnology; clinical trials; antigen presentation; formulation development; vaccine efficacy; mucosal immunity
(This special issue belongs to the Section Vaccine Design, Development, and Delivery)
Advances in Pneumococcal Vaccines: Efficacy, Implementation, and Coverage
edited by Jose María Marimón
submission deadline 31 May 2026 | Viewed by 92 | Submission Open
Keywords: pneumococcal conjugate vaccines; pneumococcal diseases; streptococcus pneumoniae serotypes; serotype replacement
(This special issue belongs to the Section Vaccines and Public Health)
Vaccines for Tuberculosis Control
edited by and Chinnaswamy Jagannath
submission deadline 15 Jun 2026 | Viewed by 154 | Submission Open
Keywords: tuberculosis vaccine; recombinant vaccines; mRNA vaccines; viral vector vaccines; peptide vaccines; DNA vaccines; live-attenuated vaccines; immunology of adjuvants; immunoinformatics; multi-omics integration
(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
Innovations in Immunotherapy and Cancer Vaccines: From Bench to Bedside
edited by
submission deadline 16 Jun 2026 | 1 articles | Viewed by 1029 | Submission Open
Keywords: cancer; immunotherapy; vaccine; preclinical and clinical studies
Peptide-Based Vaccines
edited by , and Ahmed O. Shalash
submission deadline 30 Jun 2026 | 4 articles | Viewed by 12851 | Submission Open
Keywords: peptide-based vaccines; infectious diseases; prophylactic vaccines; therapeutic vaccines; cancer; vaccine formulations; adjuvants
Host–Virus Interactions and Vaccine Development
edited by
submission deadline 30 Jun 2026 | 4 articles | Viewed by 12118 | Submission Open
Keywords: virus infection; host genes; immune regulation; innate immunity; immunological memory; vaccine efficacy
(This special issue belongs to the Section Pathogens-Host Immune Boundaries)
Immunization of Immunosuppressed Patients submission deadline 30 Jun 2026 | 6 articles | Viewed by 11271 | Submission Open
Keywords: COVID-19; vaccine efficacy; immunization
(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)
Vaccination for Patients with Respiratory Diseases
edited by and
submission deadline 30 Jun 2026 | 2 articles | Viewed by 9899 | Submission Open
Keywords: asthma; COPD; bronchiectasis; ILD; vaccines
(This special issue belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
State-of-the-Art Vaccine Design submission deadline 30 Jun 2026 | 2 articles | Viewed by 9721 | Submission Open
Keywords: vaccine; adjuvant; recombinant antigen; synthetic biology; vaccine delivery systems; universal vaccines; immunity
(This special issue belongs to the Section Vaccine Design, Development, and Delivery)
Vaccines for Porcine Viruses
edited by
submission deadline 30 Jun 2026 | 6 articles | Viewed by 6840 | Submission Open
Keywords: infections; vaccine; adaptive immune response; epidemiology
(This special issue belongs to the Section Veterinary Vaccines)
Bioengineering Strategies for Developing Vaccines
edited by Chen Zhao and Jiayi Shu
submission deadline 30 Jun 2026 | 2 articles | Viewed by 6442 | Submission Open
Keywords: vaccine platform; antigen design; targeted delivery; mRNA; nanoparticle; artificial intelligence
Mucosal Immunity and Vaccine submission deadline 30 Jun 2026 | 2 articles | Viewed by 3779 | Submission Open
Keywords: mucosal immunity; vaccine; mucosal adjuvant
(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)
Oral and Nucleic Acid Vaccines for Zoonotic and Animal Infectious Diseases
edited by Lei Shuai
submission deadline 30 Jun 2026 | 1 articles | Viewed by 3294 | Submission Open
Keywords: oral vaccines; nucleic acid vaccines; zoonotic diseases; animal infectious diseases; vaccine development; vaccine safety; vaccine efficacy; immunological mechanism
(This special issue belongs to the Section Veterinary Vaccines)
Vaccine-Induced Humoral Immunity: Mechanisms of Induction and Idiotypic Network Interactions submission deadline 30 Jun 2026 | 2 articles | Viewed by 2383 | Submission Open
Keywords: vaccines; immunoglobulin G (IgG); idiotypic network; humoral immunity; adaptive immune response
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