Vaccination for Patients with Respiratory Diseases

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Vaccines against Tropical and other Infectious Diseases".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 3503

Special Issue Editors


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Guest Editor
Department of Medicine, The University of Hong Kong, Hong Kong
Interests: COPD; asthma and bronchiectasis

E-Mail Website
Guest Editor
National Chung Hsing University, China Medical University of Taiwan, Taichung, Taiwan
Interests: COPD; asthma and interstitial lung disease

Special Issue Information

Dear Colleagues,

Respiratory diseases are common medical disorders worldwide. One of the classic clinical features of chronic respiratory diseases is exacerbation, which viral and bacterial infections can trigger. Preventing infections through vaccinations is an important way to prevent exacerbation of chronic respiratory diseases linked to adverse outcomes. We are pleased to invite you to submit articles on vaccination in patients with respiratory diseases. In this Special Issue, we welcome original research articles and reviews are welcome. Research areas may include, but are not limited to, the following: asthma, COPD, bronchiectasis, interstitial lung disease and vaccines.

Dr. Wang Chun Kwok
Prof. Pin-Kuei Fu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • asthma
  • COPD
  • bronchiectasis
  • ILD
  • vaccines

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Published Papers (2 papers)

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Review

15 pages, 266 KiB  
Review
Vaccination in Chronic Obstructive Pulmonary Disease
by Wang-Chun Kwok, Jin-Ning Clarabel Wong, Aaron Cheung and Terence Chi-Chun Tam
Vaccines 2025, 13(3), 218; https://doi.org/10.3390/vaccines13030218 - 22 Feb 2025
Viewed by 1249
Abstract
Chronic obstructive pulmonary disease (COPD) is often exacerbated by various viruses and bacteria, leading to acute episodes of worsening respiratory symptoms, which contribute significantly to the morbidity and mortality associated with COPD. Consequently, vaccination against these pathogens is recommended by numerous guidelines to [...] Read more.
Chronic obstructive pulmonary disease (COPD) is often exacerbated by various viruses and bacteria, leading to acute episodes of worsening respiratory symptoms, which contribute significantly to the morbidity and mortality associated with COPD. Consequently, vaccination against these pathogens is recommended by numerous guidelines to safeguard COPD patients from adverse health outcomes. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommendation advocates for vaccination against influenza, Streptococcus pneumoniae, respiratory syncytial virus (RSV), severe acute respiratory syndrome coronavirus (SARS-CoV2), pertussis, and varicella zoster. This review article will examine the current vaccination strategies recommended for adult COPD patients and will discuss the clinical benefits associated with these vaccines. Full article
(This article belongs to the Special Issue Vaccination for Patients with Respiratory Diseases)
22 pages, 1020 KiB  
Review
Immunological Insights and Therapeutic Advances in COPD: Exploring Oral Bacterial Vaccines for Immune Modulation and Clinical Improvement
by Sławomir Lewicki, Barbara Joanna Bałan, Marta Stelmasiak, Dorota Magdalena Radomska-Leśniewska, Łukasz Szymański, Natalia Rios-Turek, Justyna Bień-Kalinowska, Łukasz Szarpak and Bogdan Hajduk
Vaccines 2025, 13(2), 107; https://doi.org/10.3390/vaccines13020107 - 22 Jan 2025
Viewed by 1443
Abstract
Chronic obstructive pulmonary disease (COPD) is a prevalent chronic condition associated with substantial global morbidity and mortality. Primarily caused by prolonged exposure to harmful agents such as dust and gases, COPD is characterized by persistent airflow limitation, clinically manifesting as chronic cough, sputum [...] Read more.
Chronic obstructive pulmonary disease (COPD) is a prevalent chronic condition associated with substantial global morbidity and mortality. Primarily caused by prolonged exposure to harmful agents such as dust and gases, COPD is characterized by persistent airflow limitation, clinically manifesting as chronic cough, sputum production, and dyspnea. The disease course alternates between stable phases and exacerbations, with the latter often associated with pathogenic colonization of the respiratory tract. This review examines the immunological underpinnings of COPD, emphasizing the interplay between innate and adaptive immunity in disease pathogenesis. Dysregulated immune responses to environmental factors perpetuate chronic inflammation, resulting in progressive pulmonary epithelial damage and connective tissue hyperplasia, which compromise gas exchange. Exacerbations further exacerbate respiratory failure, aggravating patient symptoms and accelerating disease progression. Despite advances in COPD management, effective therapeutic options remain limited. Current treatments primarily aim to alleviate symptoms, reduce immune activation, and manage infections, yet many patients experience suboptimal outcomes. This review highlights the potential of novel therapeutic approaches targeting immune system cells and pathways. In particular, it explores the promise of oral bacterial vaccines as immunomodulatory agents to enhance immune responses and improve clinical outcomes in COPD, addressing critical gaps in current treatment paradigms. Full article
(This article belongs to the Special Issue Vaccination for Patients with Respiratory Diseases)
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