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Pathogens publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Host-Pathogen Interactions During Pathogenic Human Coronavirus Infection: 2nd Edition

edited by

Masfique Mehedi

submission deadline 31 Dec 2025 | 3 articles | Viewed by 4615 | Submission Open

Keywords: COVID-19; spike; mRNA; goblet cell; viremia; pneumonia; convalescent; antibody; transmission

(This special issue belongs to the Section Viral Pathogens)

Hepatitis E Virus (HEV) Infection Among Humans and Animals: Epidemiology, Clinical Characteristics, Treatment and Prevention—2nd Edition

edited by

Jelena Prpić

and

Magdalena Baymakova

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4583 | Submission Open

Keywords: seroprevalence; molecular analysis; clinical characteristics; prevention; treatment

(This special issue belongs to the Section Viral Pathogens)

Laboratory Diagnostics in Epidemiological Diseases Caused by Animal Pathogens

edited by

Tomasz Grenda

and

Karol Stasiak

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4445 | Submission Open

Keywords: animal pathogens; laboratory diagnostics; epidemiology; infections; toxins

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Drug Resistant Pathogens: Diagnosis, Treatment, and Global Health Implications

edited by

Giuseppe Pipitone

Alberto Enrico Maraolo

and

Luigi Principe

submission deadline 31 Dec 2025 | 4 articles | Viewed by 4187 | Submission Open

Keywords: antibiotics; multi-drug-resistant microorganisms; difficult-to-treat infections

(This special issue belongs to the Section Bacterial Pathogens)

Leishmania & Leishmaniasis

edited by

Maria Inês Fernandes Pimentel

and

Liliane de Fátima Antonio Oliveira

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3963 | Submission Open

Keywords: leishmaniasis; visceral leishmaniasis; cutaneous leishmaniasis; mucosal leishmaniasis; mucocutaneous leishmaniasis; human visceral leishmaniasis; canine visceral leishmaniasis

(This special issue belongs to the Section Parasitic Pathogens)

Covalent Inhibitors of Pathogenic Bacterial, Protozoal, Viral, and Fungal Targets

edited by

Monika I. Konaklieva

and Balbina J. Plotkin

submission deadline 31 Dec 2025 | 3 articles | Viewed by 2513 | Submission Open

Keywords: covalent inhibitors; pathogenic bacterial and viral protein targets; protozoa; fragment-based drug discovery; chemical warheads; prodrugs; STD NMR; MS; SITE (single-injection thermal extinction)

HIV/AIDS Epidemiology, Prevention and Diagnostics: Current State of Research

edited by

Lars Henning

and Maria Castellanos

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2149 | Submission Open

Keywords: HIV; AIDS; diagnostics; epidemiology; prevention

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

One Health—Viral Zoonosis: Epidemiology, Pathogenesis, Surveillance and Early Warning, Novel Prevention and Control Technologies

edited by Xuejie Yu, Xuexing Zheng and Lina Yan

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2089 | Submission Open

Keywords: viral zoonoses; epidemiology; pathogenesis; surveillance; prevention and control technologies

(This special issue belongs to the Section Viral Pathogens)

Pseudovirus-Based Strategies for Understanding and Controlling Viral Infections

edited by

Jianhui Nie

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1313 | Submission Open

Keywords: pseudovirus; infectivity; neutralization; antigenicity; immunogenicity

(This special issue belongs to the Section Viral Pathogens)

Emerging Viral Pathogens: Diagnosis, Treatment, and Public Health Interventions

edited by

Jasper Fuk-Woo Chan

and Vivian Huiping Shuai

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1199 | Submission Open

Keywords: virus discovery; pathogenesis; antivirals; diagnostics; vaccines; public health

(This special issue belongs to the Section Emerging Pathogens)

Epidemiology, Diagnosis and Clinical Management of Human Parasitic Infections—2nd Edition

edited by

Marcia Aparecida Speranca

and

Aline Diniz Cabral

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1168 | Submission Open

Keywords: parasitic infectious diseases; eco-epidemiology; diagnosis; treatment; clinical management; prevention

(This special issue belongs to the Section Parasitic Pathogens)

Emerging Technologies and Approaches for the Prevention and Treatment of Zoonotic Diseases

edited by

Alejandra Capozzo

and

Jesús Hernández

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1142 | Submission Open

Keywords: one health; zoonotic diseases; vaccines; immunotherapy and biotherapeutics; cross-species disease prevention

(This special issue belongs to the Section Vaccines and Therapeutic Developments)

Respiratory Diseases in Swine: Epidemiology, Diagnosis and Control

edited by

Arkadiusz Dors

submission deadline 31 Dec 2025 | 1 articles | Viewed by 996 | Submission Open

Keywords: swine; respiratory diseases; diagnostics; surveillance; control strategies

Surveillance, Prevention and Control of Sexually Transmitted Infections

edited by

Miguel A. Sánchez-Alemán

submission deadline 31 Dec 2025 | Viewed by 939 | Submission Open

Keywords: sexually transmitted infections; syphilis; herpes; papillomavirus; HIV; sexual health; epidemiology; reproductive health; prevention; diagnosis; treatment

Ticks and Tick-Borne Diseases in Southeast Asia

edited by

Benoit Malleret

and Jean-Marc Chavette

submission deadline 31 Dec 2025 | Viewed by 435 | Submission Open

Keywords: ticks; tick-borne pathogens; tick-borne diseases; anti-tick; one health

(This special issue belongs to the Section Ticks)

Multidrug-Resistant Microorganisms’ (MDROs) Genomic Characteristics Integrated with Serum Biomarkers Measurement in the Diagnosis and Prognosis of Severe Infectious Disease as Sepsis

edited by

Silvia Spoto

and

Silvia Angeletti

submission deadline 31 Dec 2025 | Viewed by 355 | Submission Open

Keywords: procalcitonin (PCT); mid-regional-pro-adrenomedullin (MR-proADM); multidrug-resistant microorganisms (MDRO); active surveillance cultures (ACS); healthcare-associated infections (HCAIs)

Understanding Emerging and Re-Emerging Viral Infections

edited by

Jose Angel Regla Nava

submission deadline 31 Dec 2025 | Viewed by 344 | Submission Open

Keywords: diagnosis; pathogenesis; evolution; epidemiology; drugs; vaccines

(This special issue belongs to the Section Viral Pathogens)

Malaria: Updates on Prevention, Diagnosis, and Treatment

edited by Temi Lampejo and

Andrew Taylor-Robinson

submission deadline 31 Dec 2025 | Viewed by 340 | Submission Open

Keywords: malaria; plasmodium; prevention; vaccines; therapeutics

(This special issue belongs to the Section Parasitic Pathogens)

Monitoring and Management of Mosquito-Borne Pathogens in Mosquito Populations

edited by

Bethany Bolling

and Hannah Romo

submission deadline 31 Dec 2025 | Viewed by 337 | Submission Open

Keywords: mosquitoes; arboviruses; surveillance; mosquito collection; mosquito testing; integrated mosquito management; mosquito control; response plans; outbreak response

Vector-Borne Diseases and Transboundary Zoonoses: A One Health Perspective

edited by

Rafael Felipe da Costa Vieira

and

Richard de Campos Pacheco

submission deadline 31 Dec 2025 | Viewed by 316 | Submission Open

Keywords: zoonoses; one health approach; vector control; pathogen transmission; animal reservoirs; emerging infectious diseases; veterinary medicine; disease surveillance; epidemiology

Advances in Chlamydia-Related Diseases

edited by

Katalin Burián

submission deadline 31 Dec 2025 | Viewed by 255 | Submission Open

Keywords: chlamydia; pathomechanism; host interaction; host-specific immunity; in vitro persistence model; epidemiology; treatment; vaccination

(This special issue belongs to the Section Bacterial Pathogens)

Current Research on Plant–Pathogen Interactions

edited by Ana Rita Varela and

Hon Ho

submission deadline 31 Dec 2025 | Viewed by 219 | Submission Open

Keywords: plant– microbe interactions; plant immunity; biotechnological innovations in crop protection; pathogen virulence strategies

Emerging Trends in Arbovirus Research: Diagnosis, Transmission, and Therapeutic Development

edited by

Paulo Ricardo da Silva Sanches

submission deadline 31 Dec 2025 | Viewed by 219 | Submission Open

Keywords: arboviruses; vector-borne diseases; viral pathogenesis; molecular diagnostics; antiviral therapies; vaccine develop-ment; vector control; infectious diseases

(This special issue belongs to the Section Viral Pathogens)

Diagnosis of Tuberculosis and Mycobacteriosis—Focus on Extrapulmonary Forms

edited by Jacobus H. de Waard

submission deadline 31 Dec 2025 | Viewed by 143 | Submission Open

Keywords: molecular diagnostics; imaging innovations; biomarker discovery; AI applications

(This special issue belongs to the Section Bacterial Pathogens)

Influenza A Virus: Updates and Insights

edited by

Pawel Zmora

and

Elzbieta Kierzek

submission deadline 10 Jan 2026 | 1 articles | Viewed by 2658 | Submission Open

Keywords: influenza A virus; virus– host interactions; antivirals; vaccines; epidemiology; genetic diversity; RNA structure; RNA interactions; structural biology

(This special issue belongs to the Section Viral Pathogens)

The Dark Side of Fungi: Exploring Pathogenesis in Candida and Other Fungal Pathogens

edited by

Bruna Gonçalves

Stephen A. Klotz

and

Ana V. Espinel-Ingroff

submission deadline 15 Jan 2026 | 2 articles | Viewed by 2516 | Submission Open

Keywords: fungal pathogenesis; Candida species; virulence factors; fungi– host interaction; immune evasion; antifungal resistance

(This special issue belongs to the Section Fungal Pathogens)

Molecular and Cellular Research on Targets for Antimalarial Therapy Development

edited by

Sanjay Arvind Desai

submission deadline 15 Jan 2026 | 1 articles | Viewed by 1738 | Submission Open

Keywords: malaria; molecular biology; cellular biology; antimalarial drug discovery and development; malaria vaccines

(This special issue belongs to the Section Parasitic Pathogens)

Pathogens in Dentistry: Diversity, Virulence, Resistance, and Control

edited by

Gláuber Campos Vale

submission deadline 15 Jan 2026 | Viewed by 160 | Submission Open

Keywords: oral pathogens; biofilm; dental caries; periodontitis; virulence factors; antimicrobial resistance; microbiome; infection control; molecular diagnostics; host immunity

Biomarkers and Diagnostic Advances in Oral Pathogen Detection: Exploring Microbial Diversity and Clinical Applications

edited by

Aleksandar Jakovljevic

submission deadline 15 Jan 2026 | Viewed by 134 | Submission Open

Keywords: oral pathogens; biomarkers; diagnostic methods; microbial diversity; personalized medicine

New Insights into Rickettsia and Related Organisms

edited by

Alison Luce-Fedrow

and Kristin E. Mullins

submission deadline 20 Jan 2026 | 5 articles | Viewed by 7798 | Submission Open

Keywords: Rickettsia; Orientia; Ehrlichia; Anaplasma; Coxiella; Borrelia; Bartonella; Babesia

(This special issue belongs to the Section Bacterial Pathogens)

Hand–Foot–Mouth Disease

edited by

Kow-Tong Chen

submission deadline 20 Jan 2026 | 2 articles | Viewed by 5720 | Submission Open

Keywords: hand– foot– mouth disease; Coxsackie virus; epidemiology; pathogenesis; prevention

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Updates on Animal Papillomaviruses

edited by

Francesca De Falco

and Franco Roperto

submission deadline 20 Jan 2026 | 2 articles | Viewed by 4563 | Submission Open

Keywords: papillomavirus; trans-species transmission; environmental contamination

(This special issue belongs to the Section Viral Pathogens)

Current Research on Bacillus anthracis Infection

edited by Viviana Manzulli and

Domenico Galante

submission deadline 20 Jan 2026 | 2 articles | Viewed by 3692 | Submission Open

Keywords: Bacillus anthracis; epidemiology; pathogenesis; diagnostics; genomics

(This special issue belongs to the Section Bacterial Pathogens)

Immune Pathways and Mechanisms Involved in Viral Infections

edited by

Celina Monteiro Abreu

, Lendel Correia Da Costa, Ana Carolina Soares and

Isadora Alonso Corrêa

submission deadline 20 Jan 2026 | 1 articles | Viewed by 830 | Submission Open

Keywords: viral infections; host– virus interactions; immune pathways; viral evasion; antiviral therapies; vaccine development

(This special issue belongs to the Section Viral Pathogens)

Genomic Applications in Microbial Adaptation, Antimicrobial Resistance and One Health Perspectives

edited by

Wellington Rodrigues

Aristóteles Góes-Neto

and Siomar de Castro Soares

submission deadline 20 Jan 2026 | Viewed by 235 | Submission Open

Keywords: genomics; One Health; antimicrobial resistance; pathogen evolution; metagenomics; reverse vaccinology; zoonotic diseases; mobilome; genomic surveillance; predictive modeling

Emerging and Neglected Zoonotic Pathogens in Companion Animals

edited by Olga Szalus̈-Jordanow

submission deadline 20 Jan 2026 | 1 articles | Viewed by 230 | Submission Open

Keywords: zoonotic pathogens; host– pathogen interactions; companion animals; one Health; antimicrobial resistance; emerging infectious diseases; interspecies transmission; molecular epidemiology; pathogen surveillance

(This special issue belongs to the Section Emerging Pathogens)

Focus on Cervicovaginal Health: Microbiome, Sexually Transmitted Infections, and Beneficial Microbes: 2nd Edition

edited by

Antonella Marangoni

and

Claudio Foschi

submission deadline 25 Jan 2026 | 3 articles | Viewed by 7909 | Submission Open

Keywords: vaginal microbiome; vaginal metabolome; lactobacilli; host– pathogen interactions; sexually transmitted infections; Chlamydia; gonorrhea; vaginal dysbiosis; vulvovaginal candidiasis; animal models

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Leveraging Technological Advancement for Pandemic Preparedness

edited by Kai Sen Tan,

Chee Keng MOK

Yaw Shin Ooi

, Chee Wah Tan,

Mookkan Prabakaran

, Dahai Luo and Poying Chia

submission deadline 25 Jan 2026 | 2 articles | Viewed by 2936 | Submission Open

Keywords: pandemic preparedness; disease X; technological platforms; treatment and prevention; viral infectious diseases

New Insights Into Zoonotic Intracellular Pathogens

edited by

Tarka Raj Bhatta

, Stephen Graves and

John Stenos

submission deadline 25 Jan 2026 | 2 articles | Viewed by 2347 | Submission Open

Keywords: zoonotic intracellular pathogens; bacteria; viruses; sequencing; virulence factors; immune system; vaccine development; diagnostic tools; one health

Salmonella: A Global Health Threat and Food Safety Challenge

edited by

Chyer Kim

and

Yangjin Jung

submission deadline 31 Jan 2026 | 5 articles | Viewed by 8530 | Submission Open

Keywords: salmonellosis; virulence; surveillance; climate change; and prevention

(This special issue belongs to the Section Bacterial Pathogens)

Exploring Natural Products as Antiparasitic Agents: Efficacy Against Parasites of Veterinary and Public Health Significance

edited by

Agustín Olmedo-Juárez

and

Elke Von Son-De Fernex

submission deadline 31 Jan 2026 | 6 articles | Viewed by 8218 | Submission Open

Keywords: plant extracts; phytochemicals; fungi; parasites; anthelmintics; secondary metabolites; natural compounds; ethnoveterinary

(This special issue belongs to the Section Parasitic Pathogens)

Pets, Wildlife and Parasites—2nd Edition

edited by

Anastasia Diakou

Georgiana Deak

and

Fabrizia Veronesi

submission deadline 31 Jan 2026 | 4 articles | Viewed by 3884 | Submission Open

Keywords: pet animals; dog; cat; wildlife; wild animals; parasites; zoonosis

(This special issue belongs to the Section Parasitic Pathogens)

The Interplay of Microbiota and Polyomaviruses in Human Health and Disease

edited by

Valeria Pietropaolo

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3317 | Submission Open

Keywords: human polyomaviruses (HPyVs); microbiota; co-infection patterns; cancer; diagnostic markers; cellular pathways; immunosuppression

(This special issue belongs to the Section Viral Pathogens)

Advances in the Surveillance and Prevention of Healthcare-Associated Infections

edited by

Francesca J. Torriani

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2710 | Submission Open

Keywords: healthcare-associated infections (HAIs); nosocomial infections; HAI-associated pathogens; infection prevention and control; antimicrobial resistance and antimicrobial stewardship

Infectious Diseases in Aquatic Animals

edited by Roberto Bermúdez Pose

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2605 | Submission Open

Keywords: infectious diseases; aquatic animals; pathogens; host– pathogen interactions; immune response

Hospital-Acquired Infections: Risk Factors and Preventions—2nd Edition

edited by

Gabriele Messina

and

Davide Amodeo

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1766 | Submission Open

Keywords: surgical site infection; dialysis infection; burn infection; bacterial infections; Legionella; Clostridium difficile; ventilator-associated pneumonia prevention; female urinary catheter in urinary tract infection prevention; endoscope sterilisation and disinfection

Gut–Brain Axis in Neurodevelopment: Microbial Metabolites and Neurological Function

edited by

Xuesong Zhang

and

Ningning Li

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1227 | Submission Open

Keywords: microbiome; gut– brain axis; microbial metabolites; neurodevelopment; host– microbe interaction

Infectious Diseases in Pediatric Populations: Clinical Challenges and Emerging Perspectives

edited by Piero Pavone,

Roberta Leonardi

and Manuela Lo Bianco

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1173 | Submission Open

Keywords: pediatric infectious diseases and immune responses; post-infectious syndromes; diagnosis and treatment of pediatric infectious diseases; pediatric microbiome; viral; fungal; and bacterial infections in children

Advances in Molecular Characterization and Epidemiology of Plant Viruses

edited by