Current Research on Plant–Pathogen Interactions

A special issue of Pathogens (ISSN 2076-0817).

Deadline for manuscript submissions: closed (31 December 2025) | Viewed by 702

Special Issue Editors


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Guest Editor
INIAV, I.P., National Institute for Agrarian and Veterinary Research, Quinta do Marquês, 2780-159 Oeiras, Portugal
Interests: plant–pathogen interactions; molecular diagnosis; plant immunity; plant resistance
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Guest Editor
Department of Biology, State University of New York at New Paltz, New Paltz, NY 12561, USA
Interests: mycology; plant pathology; microbiology; plant sciences

Special Issue Information

Dear Colleagues,

The intricate relationship between plants and microbes has shaped the evolution of plant defense mechanisms and refined pathogen strategies over millennia. This evolutionary arms race has led to the emergence of sophisticated defense responses, including effector-triggered immunity and the regulation of resistance genes. Conversely, pathogens have evolved equally complex strategies, such as effector secretion to suppress host immunity, the manipulation of host cellular processes, and rapid genetic diversification to evade recognition.

With global agricultural systems facing increasing challenges due to climate change and pathogen movement facilitated by global trade, we are launching this Special Issue to highlight cutting-edge research in plant–pathogen interactions, mainly at the molecular level. Understanding these intricate molecular interactions provides a foundation for developing pest-resistant crops. By leveraging insights into plant immune responses, researchers can design targeted strategies to enhance resistance, ensuring sustainable agricultural practices and global food security.

This Special Issue will explore the latest breakthroughs in understanding plant viral diseases at both the molecular and cellular levels, contributing to the development of new and effective disease management strategies and biotechnological innovations for crop protection.

Original research articles, review papers, and case studies related to these core themes are encouraged. Additionally, other relevant studies within this field are welcome. The scope of this Special Issue includes, but is not limited to, the following topics:

  • Molecular mechanisms behind plant immunity;
  • Pathogen strategies for overcoming plant defenses;
  • Advancements in pathogen detection: sensitivity and significance;
  • Impacts of environmental factors on plant–pathogen interactions;
  • Biotechnological and ecological strategies for disease management. 

Dr. Ana Rita Varela
Prof. Dr. Hon Ho
Guest Editors

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Keywords

  • plant–microbe interactions
  • plant immunity
  • biotechnological innovations in crop protection
  • pathogen virulence strategies

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Published Papers (1 paper)

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Research

17 pages, 6933 KB  
Article
TaERF109: A Novel ERF Transcription Factor Contributing to Enhanced Resistance to Puccinia graminis f. sp. tritici Infection in Wheat
by Binbin Si, Jiahui Lei, Wufen Zhang, Rong Ma and Yuanyin Cao
Pathogens 2026, 15(4), 387; https://doi.org/10.3390/pathogens15040387 - 4 Apr 2026
Viewed by 344
Abstract
Puccinia graminis f. sp. tritici (Pgt) is responsible for stem rust in wheat, a disease with worldwide occurrence. Ethylene response factors (ERFs), a group of transcription factors (TFs) responsive to ethylene, are essential for managing stress signaling under biotic and abiotic [...] Read more.
Puccinia graminis f. sp. tritici (Pgt) is responsible for stem rust in wheat, a disease with worldwide occurrence. Ethylene response factors (ERFs), a group of transcription factors (TFs) responsive to ethylene, are essential for managing stress signaling under biotic and abiotic challenges. However, our understanding of ERF TFs’ function in wheat (Triticum aestivum L.) resistance against the obligate biotrophic Puccinia graminis f. sp. tritici remains limited. In this work, we report our findings of the TaERF109 gene, which is transcriptionally up-regulated by ethylene or Pgt infection. TaERF109 is localized in the nucleus of rice protoplasts. Results obtained using the yeast one-hybrid (Y1H) assay support the conclusion that TaERF109 interacts with the AGCCGCC sequence (GCC-box). Transient knockdown of TaERF109 via virus-induced gene silencing (VIGS) increased wheat susceptibility to Pgt, accompanied by the down-regulation of three pathogenesis-related (PR) genes, TaPR1, TaPR2, and TaPR10, as confirmed via real-time quantitative PCR. In contrast, the Agrobacterium-mediated overexpression of TaERF109 potentiated resistance of transgenic wheat against Pgt. Overall, these results expand the current understanding of the TaERF109 gene’s function in wheat resistance to Pgt. Full article
(This article belongs to the Special Issue Current Research on Plant–Pathogen Interactions)
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