Host-Pathogen Interactions During Pathogenic Human Coronavirus Infection: 2nd Edition
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Viral Pathogens".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 5065
Special Issue Editor
Interests: host-pathogen interactions; RSV; SARS-CoV-2; cytoskeletal inflammation; respiratory diseases; live-attenuated vaacine; HMPV; HPIV; IAV; organ-on-chip; air-liquid interface
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, a causative agent of coronavirus disease 2019 (COVID-19)), is an enveloped virus responsible for the current never-ending pandemic, which began when the virus emerged in December 2019 in Wuhan, China. SARS-CoV-2 spreads from human to human through aerosol and respiratory droplet-based virus transmission. SARS-CoV-2 contains a non-segmented, positive-sense, single-strand RNA genome. With this genome, two-thirds of viral RNA is translated into large polyproteins, and a discontinuous transcription process transcribes the remainder of the viral genome into a nested set of subgenomic mRNAs, thus making it unique. Respiratory viruses appear to be diverse in cellular tropism, resulting in differences in virus-induced pathobiology, e.g., respiratory syncytial virus causes bronchiolitis, but SARS-COV-2 primarily causes pneumonia. Unlike many respiratory viruses, SARS-CoV-2 causes a systemic infection, resulting in multiorgan infection and severe pathophysiology.
This Special Issue will cover a broad understanding of SARS-CoV-2 infection, including cell tropism, strain and variants, pathophysiology, ARDS, vaccine and therapeutics, vaccine injury, treatment, animal models, viral protein characterization, genome, immune response, cytoskeletal signaling, and the convalescent stage of SARS-CoV-2 infection.
Dr. Masfique Mehedi
Guest Editor
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Keywords
- COVID-19
- spike
- mRNA
- goblet cell
- viremia
- pneumonia
- convalescent
- antibody
- transmission
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